umu.sePublications
Change search
ReferencesLink to record
Permanent link

Direct link
Debridement, antibiotics and implant retention in early periprosthetic joint infection
Umeå University, Faculty of Medicine, Department of Surgical and Perioperative Sciences.
Show others and affiliations
2016 (English)In: HIP International, ISSN 1120-7000, E-ISSN 1724-6067, Vol. 26, no 2, 138-143 p.Article in journal (Refereed) PublishedText
Abstract [en]

Introduction: Periprosthetic joint infection (PJI) is a devastating complication in hip arthroplasty surgery. Debridement, antibiotics (AB) and implant retention (DAIR) is recommended in early PJI in association with stable implants. The aim of this study was to evaluate the success rate of DAIR in early PJI (<4 weeks) and to identify factors predicting the outcome. Methods: This cohort study included a consecutive series of 35 patients (median age 74 years, 25 women, 26 primary arthroplasties) treated with DAIR for an early PJI in a regional hospital. Results: 28 patients (80%) had their infection eradicated. DAIR-only eradicated the PJI in 22 (63%) patients with a median follow-up of 50 (24-84) months. In 17 (49%) patients, oral AB had been given prior to intraoperative cultures, which delayed first debridement with average 6 days and delayed hospital stay. Primary surgery for a hip fracture increased the risk of DAIR-failure. Surgical experience did not affect the outcome. 17% (n = 6) of the patients sustained a secondary infection during their hospital stay; the majority was beta-lactam resistant coagulase negative Staphylococcus aureus. Conclusions: The success rate of DAIR was inferior to pervious controls from experienced revision centers. Hip fracture patients should be informed about the increased risk of DAIR treatment failure. In order not to delay surgery, empirically based oral AB should not be administered prior to deep cultures.

Place, publisher, year, edition, pages
2016. Vol. 26, no 2, 138-143 p.
Keyword [en]
Antibiotics, Debridement, Hip arthroplasty, Implant retention, Outcome, Periprosthetic joint infection
National Category
Surgery
Identifiers
URN: urn:nbn:se:umu:diva-121602DOI: 10.5301/hipint.5000328ISI: 000375128300009PubMedID: 26868114OAI: oai:DiVA.org:umu-121602DiVA: diva2:940686
Available from: 2016-06-21 Created: 2016-06-03 Last updated: 2016-06-21Bibliographically approved

Open Access in DiVA

No full text

Other links

Publisher's full textPubMed

Search in DiVA

By author/editor
Mukka, Sebastian S.Sayed-Noor, Arkan S.
By organisation
Department of Surgical and Perioperative Sciences
In the same journal
HIP International
Surgery

Search outside of DiVA

GoogleGoogle Scholar
The number of downloads is the sum of all downloads of full texts. It may include eg previous versions that are now no longer available

Altmetric score

Total: 11 hits
ReferencesLink to record
Permanent link

Direct link