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Rheological characterization of vocal folds after injection augmentation in a preliminary animal study
Umeå University, Faculty of Medicine, Department of Clinical Sciences, Otorhinolaryngology.
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2004 (English)In: Journal of bioactive and compatible polymers (Print), ISSN 0883-9115, E-ISSN 1530-8030, Vol. 19, no 4, 331-341 p.Article in journal (Refereed) PublishedText
Abstract [en]

The investigation of vocal folds viscoelastic properties in an animal model (rabbit) after injection of various augmentation substances, 6 months after injection, is reported. The injected materials were: hyaluronan-based materials (Hylan B gel and Deflux(R)), cross-linked collagen (Zyplast(R)) and polytetrafluoroethylene (Teflon(R)). Rheological properties of the augmentation substances were also evaluated. The results from these animal experiments indicate that the viscoelastic properties of the vocal folds injected with Deflux(R), Zyplast(R) and Hylan B gel are similar to the healthy vocal folds (non-injected samples) used as control, thus demonstrating that these materials are good candidates for further studies aimed at restoring/preserving the vibratory capacity of the vocal folds with injection treatment in glottal insufficiency.

Place, publisher, year, edition, pages
London: Sage Publications, 2004. Vol. 19, no 4, 331-341 p.
Keyword [en]
viscoelasticity, vocal folds, injection, augmentation, hyaluronan
National Category
Medical Biotechnology Medical Biotechnology (with a focus on Cell Biology (including Stem Cell Biology), Molecular Biology, Microbiology, Biochemistry or Biopharmacy)
Identifiers
URN: urn:nbn:se:umu:diva-122164DOI: 10.1177/0883911504045229ISI: 000222856900006OAI: oai:DiVA.org:umu-122164DiVA: diva2:940846
Available from: 2016-06-21 Created: 2016-06-15 Last updated: 2016-06-21Bibliographically approved

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Mayol, LGärskog, OlaDahlqvist, Åke
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Journal of bioactive and compatible polymers (Print)
Medical BiotechnologyMedical Biotechnology (with a focus on Cell Biology (including Stem Cell Biology), Molecular Biology, Microbiology, Biochemistry or Biopharmacy)

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