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  • 1. Andersson, Linus
    et al.
    Claeson, Anna-Sara
    Umeå universitet, Samhällsvetenskapliga fakulteten, Institutionen för psykologi.
    Sandberg, Petra
    Umeå universitet, Samhällsvetenskapliga fakulteten, Institutionen för psykologi.
    Highlighting the large variation in perceived properties of odors over time2017Ingår i: Chemical Senses, ISSN 0379-864X, E-ISSN 1464-3553, Vol. 42, nr 2, s. E26-E26Artikel i tidskrift (Refereegranskat)
  • 2.
    Andersson, Linus
    et al.
    Umeå universitet, Samhällsvetenskapliga fakulteten, Institutionen för psykologi. Department of Occupational and Public Health Sciences, University of Gävle, Box 7629, SE-90712 Umeå, Sweden.
    Sandberg, Petra
    Umeå universitet, Samhällsvetenskapliga fakulteten, Institutionen för psykologi.
    Olofsson, Jonas K.
    Nordin, Steven
    Umeå universitet, Samhällsvetenskapliga fakulteten, Institutionen för psykologi.
    Effects of Task Demands on Olfactory, Auditory, and Visual Event-Related Potentials Suggest Similar Top-Down Modulation Across Senses2018Ingår i: Chemical Senses, ISSN 0379-864X, E-ISSN 1464-3553, Vol. 43, nr 2, s. 129-134Artikel i tidskrift (Refereegranskat)
    Abstract [en]

    A widely held view is that top-down modulation of sensory information relies on an amodal control network that acts through the thalamus to regulate incoming signals. Olfaction lacks a direct thalamic projection, which suggests that it may differ from other modalities in this regard. We investigated the late positive complex (LPC) amplitudes of event-related potentials (ERP) from 28 participants, elicited by intensity-matched olfactory, auditory and visual stimuli, during a condition of focused attention, a neutral condition, and a condition in which stimuli were to be actively ignored. Amplitudes were largest during the attend condition, lowest during the ignore condition, with the neutral condition in between. A Bayesian analysis resulted in strong evidence for similar effects of task across sensory modalities. We conclude that olfaction, despite its unique neural projections, does not differ from audition and vision in terms of task-dependent neural modulation of the LPC.

  • 3.
    Claeson, Anna-Sara
    et al.
    Umeå universitet, Samhällsvetenskapliga fakulteten, Institutionen för psykologi.
    Gouveia-Figueira, Sandra
    Umeå universitet, Teknisk-naturvetenskapliga fakulteten, Kemiska institutionen.
    Fowler, Christopher J.
    Umeå universitet, Medicinska fakulteten, Institutionen för farmakologi och klinisk neurovetenskap, Farmakologi.
    Nording, Malin L.
    Umeå universitet, Teknisk-naturvetenskapliga fakulteten, Kemiska institutionen.
    Perceived stress, sensory irritation and levels of prostaglandin F2 alpha in plasma after acrolein exposure: a pilot study2017Ingår i: Chemical Senses, ISSN 0379-864X, E-ISSN 1464-3553, Vol. 42, nr 2, s. E28-E28Artikel i tidskrift (Refereegranskat)
  • 4.
    Croy, Ilona
    et al.
    Department of Occupational and Environmental Medicine, Gothenburg University, Göteborg, Sweden and Smell & Taste Clinic, Department of Otorhinolaryngology, University of Dresden Medical School, Dresden, Germany.
    Nordin, Steven
    Umeå universitet, Samhällsvetenskapliga fakulteten, Institutionen för psykologi. Smell & Taste Clinic, Department of Otorhinolaryngology, University of Dresden Medical School, Dresden, Germany.
    Hummel, Thomas
    Smell & Taste Clinic, Department of Otorhinolaryngology, University of Dresden Medical School, Germany.
    Olfactory Disorders and Quality of Life-An Updated Review2014Ingår i: Chemical Senses, ISSN 0379-864X, E-ISSN 1464-3553, Vol. 39, nr 3, s. 185-194Artikel i tidskrift (Refereegranskat)
    Abstract [en]

    Olfactory disorders are common and affect about one-fifth of the general population. The main causes of olfactory loss are post viral upper respiratory infection, nasal/sinus disease, and head trauma and are therefore very frequent among patients in ear, nose, and throat clinics. We have systematically reviewed the impact of quantitative, qualitative, and congenital olfactory disorders on daily life domains as well as on general quality of life and depression. From the extensive body of literature, it can be concluded that loss of the sense of smell leads to disturbances in important areas, mainly in food enjoyment, detecting harmful food and smoke, and to some extent in social situations and working life. Most patients seem to deal well and manage those restrictions. However, a smaller proportion has considerable problems and expresses a noticeable reduction in general quality of life and enhanced depression. The impact of coping strategies is discussed.

  • 5. Ekström, Ingrid
    et al.
    Josefsson, Maria
    Umeå universitet, Samhällsvetenskapliga fakulteten, Enheten för demografi och åldrandeforskning (CEDAR). Umeå universitet, Medicinska fakulteten, Umeå centrum för funktionell hjärnavbildning (UFBI).
    Larsson, Maria
    Rönnlund, Michael
    Umeå universitet, Samhällsvetenskapliga fakulteten, Institutionen för psykologi.
    Nordin, Steven
    Umeå universitet, Samhällsvetenskapliga fakulteten, Institutionen för psykologi.
    Olofsson, Jonas K.
    Subjective olfactory loss in older adults concurs with long-term odor identification decline2019Ingår i: Chemical Senses, ISSN 0379-864X, E-ISSN 1464-3553, Vol. 44, nr 2, s. 105-112Artikel i tidskrift (Refereegranskat)
    Abstract [en]

    Olfactory impairments may provide early indications of future health outcomes in older adults. Thus, an important question concerns whether these impairments can be self-assessed. Previous findings of cross-sectional studies indicate low correlations between self-reported olfactory function and objective olfactory performance. On the other hand, subjective olfactory impairments predict future dementia and mortality in longitudinal settings. No previous study has assessed the relationship between subjectively and objectively measured decline in olfaction over time. Based on data for 903 older adults derived from the Betula Study, a Swedish population-based prospective study, we tested whether rate-of-change in odor identification could be predicted from subjective olfactory decline over a time span of 10 years during which subjective and objective odor functions were assessed on 2 or 3 test occasions. Indeed, we found that participants who experienced subjective olfactory decline over the study period also had significantly steeper rates of decline in odor identification, even after adjusting for demographic, cognitive, and genetic factors that previously have been associated with performance in odor identification. This association was, however, not present in a subsample with baseline cognitive impairment. We interpret these results as evidence that when asked about whether they have an olfactory impairment or not, older persons are assessing intraindividual olfactory changes, rather than interindividual differences. Our results indicate that subjective olfactory loss reflects objective olfactory decline in cognitively intact older adults. This association might be harnessed to predict health outcomes and highlights the need to develop effective olfactory self-assessments.

  • 6.
    Nordin, Steven
    et al.
    Umeå universitet, Samhällsvetenskapliga fakulteten, Institutionen för psykologi.
    Broman, Daniel A
    Umeå universitet, Samhällsvetenskapliga fakulteten, Institutionen för psykologi.
    Olofsson, Jonas K
    Umeå universitet, Samhällsvetenskapliga fakulteten, Institutionen för psykologi.
    Wulff, Marianne
    Umeå universitet, Medicinska fakulteten, Institutionen för klinisk vetenskap, Obstetrik och gynekologi.
    A longitudinal descriptive study of self-reported abnormal smell and taste perception in pregnant women2004Ingår i: Chemical Senses, ISSN 0379-864X, E-ISSN 1464-3553, Vol. 29, nr 5, s. 391-402Artikel i tidskrift (Refereegranskat)
    Abstract [en]

    Self-reported abnormal sensitivity, qualitative distortions and phantom sensations with respect to smell and taste was assessed with a longitudinal design, based on questions referring to gestational weeks 13–16 and 31–34 of pregnancy in comparison with 9–12 weeks post partum and with non-pregnant women with corresponding time durations and intervals. The results show that abnormal smell and/or taste perception was reported by 76% of the pregnant women, typically believed to be caused by their pregnancy. Increased smell sensitivity was found to be very common at the early stage of pregnancy (67% of all pregnant respondents) and occasionally accompanied by qualitative smell distortions (17%) and phantom smells (14%). The smell abnormalities were less common at the late pregnancy stage and almost absent post partum. Abnormal taste sensitivity was fairly commonly reported (26%), often described as increased bitter sensitivity and decreased salt sensitivity. These results, suggesting that abnormal smell and/or taste perception is experienced by a large majority of pregnant women, imply that further research is needed to understand to what extent these chemosensory changes may underlie food aversions and craving with implications for food intake during pregnancy.

  • 7.
    Olofsson, Jonas
    et al.
    Umeå universitet, Samhällsvetenskapliga fakulteten, Institutionen för psykologi.
    Broman, Daniel
    Umeå universitet, Samhällsvetenskapliga fakulteten, Institutionen för psykologi.
    Gilbert, Paul
    Department of Psychology, San Diego State University, San Diego, CA, USA .
    Dean, Pamela
    Department of Psychology, San Diego State University, San Diego, CA, USA .
    Nordin, Steven
    Umeå universitet, Samhällsvetenskapliga fakulteten, Institutionen för psykologi.
    Murphy, Claire
    Department of Psychology, San Diego State University, San Diego, CA, USA .
    Laterality of the olfactory event-related potential response2006Ingår i: Chemical Senses, ISSN 0379-864X, E-ISSN 1464-3553, Vol. 31, nr 7, s. 699-704Artikel i tidskrift (Refereegranskat)
  • 8. Olofsson, Jonas K.
    et al.
    Josefsson, Maria
    Umeå universitet, Samhällsvetenskapliga fakulteten, Handelshögskolan vid Umeå universitet, Statistik.
    Stanciu, Ingrid
    Wilson, Donald
    Nordin, Steven
    Umeå universitet, Samhällsvetenskapliga fakulteten, Institutionen för psykologi.
    Nilsson, Lars-Goran
    Nyberg, Lars
    Umeå universitet, Medicinska fakulteten, Institutionen för strålningsvetenskaper.
    Larsson, Maria
    ApoE-e4 Mediates the Association Between Episodic Memory Decline and Olfactory Identification Deficit2015Ingår i: Chemical Senses, ISSN 0379-864X, E-ISSN 1464-3553, Vol. 40, nr 7, s. 667-667Artikel i tidskrift (Övrigt vetenskapligt)
  • 9. Stanciu, Ingrid
    et al.
    Larsson, Maria
    Nordin, Steven
    Umeå universitet, Samhällsvetenskapliga fakulteten, Institutionen för psykologi.
    Adolfsson, Rolf
    Umeå universitet, Medicinska fakulteten, Institutionen för klinisk vetenskap, Psykiatri.
    Nilsson, Lars-Göran
    Olofsson, Jonas K
    Olfactory impairment and subjective olfactory complaints independently predict conversion to dementia2015Ingår i: Chemical Senses, ISSN 0379-864X, E-ISSN 1464-3553, Vol. 40, nr 3, s. 260-260Artikel i tidskrift (Övrigt vetenskapligt)
  • 10. Wehling, Eike I.
    et al.
    Lundervold, Astri J.
    Nordin, Steven
    Umeå universitet, Samhällsvetenskapliga fakulteten, Institutionen för psykologi.
    Wollschlaeger, Daniel
    Longitudinal Changes in Familiarity, Free and Cued Odor Identification, and Edibility Judgments for Odors in Aging Individuals2016Ingår i: Chemical Senses, ISSN 0379-864X, E-ISSN 1464-3553, Vol. 41, nr 2, s. 155-161Artikel i tidskrift (Refereegranskat)
    Abstract [en]

    This longitudinal study investigated changes in olfaction as assessed by a set of tasks requiring different aspects of semantic information in normal aging individuals. Using 16 odorous items from a standardized olfactory test, the Scandinavian Odor Identification Test, 107 middle aged and older adults were assessed up to three times over a period of 6.5 years, requesting them to rate familiarity and edibility for each odorous item before identifying it with or without presenting verbal cues. Using linear mixed models, the longitudinal analyses revealed significant correlations between all olfactory measures. Furthermore, we found an almost parallel age-related decline in all olfactory tasks, although free identification performance indicated a trend toward faster decline with age. Women showed less decline compared with men, in particular for edibility judgments. The results corroborate earlier cross-sectional findings showing significant correlations between the olfactory tasks. In the present study of healthy middle-aged and older adults, we found a parallel longitudinal decline across different tests of olfaction.

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