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  • 1.
    Han, Jing
    et al.
    College of Public Health, Health Science Center, Xi'an Jiaotong University, Xi'an, China.
    Yu, Fang Fang
    College of Public Health, Health Science Center, Xi'an Jiaotong University, Xi'an, China.
    Chang, Zai Ping
    Department of Surgery, The Second Hospital of Weinan City, Weinan, China.
    Yang, Bo
    Department of Laboratory Medicine, The First Affiliated Hospital of Xi'an Jiaotong University, Xi'an, China.
    Qu, Cheng Juan
    Department of Applied Physics, University of Eastern Finland, Kuopio, Finland.
    Zhou, Tian Tian
    College of Public Health, Health Science Center, Xi'an Jiaotong University, Xi'an, China.
    Liu, Rui Yu
    Department of Orthopedics, The Second Affiliated Hospital of Xi'an Jiaotong University, Xi'an, China.
    Guo, Xiong
    College of Public Health, Health Science Center, Xi'an Jiaotong University, Xi'an, China.
    Changing grains for the prevention and treatment of Kashin-Beck disease in children: a Meta-analysis2015In: Biomedical and environmental sciences, ISSN 0895-3988, E-ISSN 2214-0190, Vol. 28, no 4, p. 308-311Article in journal (Refereed)
    Abstract [en]

    To evaluate the efficacy of changing grains on the prevention and treatment of Kashin-Beck Disease (KBD) in children, community-based trials were acquired from seven electronic databases (up to July 2014). As a result, the methodological quality of the six trials that have been included into our analysis was low. The pooled ORs favoring the prevention and treatment effects of changing grains were 0.15 (95% CI: 0.03-0.70) and 2.13 (95% CI: 1.44-3.16) respectively by meta-analysis. Subgroup analysis demonstrated the pooled OR favoring treatment effect of exchanging grains rather than drying grains both compared with endemic grains. The results showed that changing grains had obvious effects on the prevention and treatment of KBD in children. However, the evidences were limited by the potential biases and confounders. Large and well-designed trials are still needed.

  • 2. Yu, Fang Fang
    et al.
    Lin, Xia Lu
    Yang, Lei
    Liu, Huan
    Wang, Xi
    Fang, Hua
    Lammi, Mikko J.
    Umeå University, Faculty of Medicine, Department of Integrative Medical Biology (IMB). Institute of Endemic Diseases, School of Public Health of Health Science Center, Xi’an Jiaotong University, Key Laboratory of Trace Elements and Endemic Diseases, National Health and Family Planning Commission, Xi’an 710061, Shaanxi, China.
    Guo, Xiong
    Comparison of T-2 Toxin and HT-2 Toxin Distributed in the Skeletal System with That in Other Tissues of Rats by Acute Toxicity Test2017In: Biomedical and environmental sciences, ISSN 0895-3988, E-ISSN 2214-0190, Vol. 30, no 11, p. 851-854Article in journal (Refereed)
    Abstract [en]

    Twelve healthy rats were divided into the T-2 toxin group receiving gavage of 1 mg/kg T-2 toxin and the control group receiving gavage of normal saline. Total relative concentrations of T-2 toxin and HT-2 toxin in the skeletal system (thighbone, knee joints, and costal cartilage) were significantly higher than those in the heart, liver, and kidneys (P < 0.05). The relative concentrations of T-2 toxin and HT-2 toxin in the skeletal system (thighbone and costal cartilage) were also significantly higher than those in the heart, liver, and kidneys. The rats administered T-2 toxin showed rapid metabolism compared with that in rats administered HT-2 toxin, and the metabolic conversion rates in the different tissues were 68.20%-90.70%.

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