umu.sePublications
Change search
Refine search result
1 - 9 of 9
CiteExportLink to result list
Permanent link
Cite
Citation style
  • apa
  • ieee
  • modern-language-association-8th-edition
  • vancouver
  • Other style
More styles
Language
  • de-DE
  • en-GB
  • en-US
  • fi-FI
  • nn-NO
  • nn-NB
  • sv-SE
  • Other locale
More languages
Output format
  • html
  • text
  • asciidoc
  • rtf
Rows per page
  • 5
  • 10
  • 20
  • 50
  • 100
  • 250
Sort
  • Standard (Relevance)
  • Author A-Ö
  • Author Ö-A
  • Title A-Ö
  • Title Ö-A
  • Publication type A-Ö
  • Publication type Ö-A
  • Issued (Oldest first)
  • Issued (Newest first)
  • Created (Oldest first)
  • Created (Newest first)
  • Last updated (Oldest first)
  • Last updated (Newest first)
  • Disputation date (earliest first)
  • Disputation date (latest first)
  • Standard (Relevance)
  • Author A-Ö
  • Author Ö-A
  • Title A-Ö
  • Title Ö-A
  • Publication type A-Ö
  • Publication type Ö-A
  • Issued (Oldest first)
  • Issued (Newest first)
  • Created (Oldest first)
  • Created (Newest first)
  • Last updated (Oldest first)
  • Last updated (Newest first)
  • Disputation date (earliest first)
  • Disputation date (latest first)
Select
The maximal number of hits you can export is 250. When you want to export more records please use the Create feeds function.
  • 1. Beghi, Ettore
    et al.
    Carpio, Arturo
    Forsgren, Lars
    Umeå University, Faculty of Medicine, Department of Pharmacology and Clinical Neuroscience, Neurology.
    Hesdorffer, Dale C
    Malmgren, Kristina
    Sander, Josemir W
    Tomson, Torbjorn
    Hauser, W Allen
    Recommendation for a definition of acute symptomatic seizure2010In: Epilepsia, ISSN 0013-9580, E-ISSN 1528-1167, Vol. 51, no 4, p. 671-675Article in journal (Refereed)
    Abstract [en]

    Acute symptomatic seizures must be distinguished from unprovoked seizures and separately categorized for epidemiologic purposes. These recommendations are based upon the best available data at the time of this report. Systematic studies should be undertaken to better define the associations in question, with special reference to metabolic and toxic insults, for which the time window for the occurrence of an acute symptomatic seizure and the absolute values for toxic and metabolic dysfunction still require a clear identification.

  • 2. Fisher, Robert S.
    et al.
    Acevedo, Carlos
    Arzimanoglou, Alexis
    Bogacz, Alicia
    Cross, J. Helen
    Elger, Christian E.
    Engel, Jerome, Jr.
    Forsgren, Lars
    Umeå University, Faculty of Medicine, Department of Pharmacology and Clinical Neuroscience, Clinical Neuroscience.
    French, Jacqueline A.
    Glynn, Mike
    Hesdorffer, Dale C.
    Lee, B. I.
    Mathern, Gary W.
    Moshe, Solomon L.
    Perucca, Emilio
    Scheffer, Ingrid E.
    Tomson, Torbjorn
    Watanabe, Masako
    Wiebe, Samuel
    ILAE official report: a practical clinical definition of epilepsy2014In: Epilepsia, ISSN 0013-9580, E-ISSN 1528-1167, Vol. 55, no 4, p. 475-482Article in journal (Refereed)
    Abstract [en]

    Epilepsy was defined conceptually in 2005 as a disorder of the brain characterized by an enduring predisposition to generate epileptic seizures. This definition is usually practically applied as having two unprovoked seizures >24h apart. The International League Against Epilepsy (ILAE) accepted recommendations of a task force altering the practical definition for special circumstances that do not meet the two unprovoked seizures criteria. The task force proposed that epilepsy be considered to be a disease of the brain defined by any of the following conditions: (1) At least two unprovoked (or reflex) seizures occurring >24h apart; (2) one unprovoked (or reflex) seizure and a probability of further seizures similar to the general recurrence risk (at least 60%) after two unprovoked seizures, occurring over the next 10years; (3) diagnosis of an epilepsy syndrome. Epilepsy is considered to be resolved for individuals who either had an age-dependent epilepsy syndrome but are now past the applicable age or who have remained seizure-free for the last 10years and off antiseizure medicines for at least the last 5years. "Resolved" is not necessarily identical to the conventional view of "remission or "cure." Different practical definitions may be formed and used for various specific purposes. This revised definition of epilepsy brings the term in concordance with common use. A PowerPoint slide summarizing this article is available for download in the Supporting Information section.

  • 3. Fisher, Robert S.
    et al.
    Acevedo, Carlos
    Arzimanoglou, Alexis
    Bogacz, Alicia
    Cross, J. Helen
    Elger, Christian E.
    Engel, Jerome, Jr.
    Forsgren, Lars
    Umeå University, Faculty of Medicine, Department of Pharmacology and Clinical Neuroscience, Clinical Neuroscience.
    French, Jacqueline A.
    Hesdorffer, Dale C.
    Lee, Byung-In
    Mathern, Gary W.
    Moshe, Solomon L.
    Perucca, Emilio
    Scheffer, Ingrid E.
    Tomson, Torbjorn
    Watanabe, Masako
    Wiebe, Samuel
    How long for epilepsy remission in the ILAE definition?2017In: Epilepsia, ISSN 0013-9580, E-ISSN 1528-1167, Vol. 58, no 8, p. 1486-1487Article in journal (Refereed)
  • 4.
    Ibinda, Fredrick
    et al.
    KEMRI Wellcome Trust Res Programme, Ctr Geog Med Res Coast, Kilifi, Kenya.
    Wagner, Ryan
    Umeå University, Faculty of Medicine, Department of Public Health and Clinical Medicine. MRC/Wits Rural Public Health and Health Transitions Research Unit (Agincourt), Faculty of Health Sciences, School of Public Health, University of the Witwatersrand, Acornhoek, South Africa.
    Bertram, Melanie Y.
    WHO, CH-1211 Geneva, Switzerland.
    Ngugi, Anthony K.
    KEMRI Wellcome Trust Res Programme, Ctr Geog Med Res Coast, Kilifi, Kenya.
    Bauni, Evasius
    KEMRI Wellcome Trust Res Programme, Ctr Geog Med Res Coast, Kilifi, Kenya.
    Vos, Theo
    Univ Washington, Inst Hlth Metr & Evaluat, Seattle, USA.
    Sander, Josemir W.
    UCL Inst Neurol, NIHR Univ Coll London Hosp Biomed Res Ctr, Dept Clin & Expt Epilepsy, London, England.
    Newton, Charles R.
    KEMRI Wellcome Trust Res Programme, Ctr Geog Med Res Coast, Kilifi, Kenya.
    Burden of epilepsy in rural Kenya measured in disability-adjusted life years2014In: Epilepsia, ISSN 0013-9580, E-ISSN 1528-1167, Vol. 55, no 10, p. 1626-1633Article in journal (Refereed)
    Abstract [en]

    Objectives

    The burden of epilepsy, in terms of both morbidity and mortality, is likely to vary depending on the etiology (primary [genetic/unknown] vs. secondary [structural/metabolic]) and with the use of antiepileptic drugs (AEDs). We estimated the disability-adjusted life years (DALYs) and modeled the remission rates of active convulsive epilepsy (ACE) using epidemiologic data collected over the last decade in rural Kilifi, Kenya.

    Methods

    We used measures of prevalence, incidence, and mortality to model the remission of epilepsy using disease-modeling software (DisMod II). DALYs were calculated as the sum of Years Lost to Disability (YLD) and Years of Life Lost (YLL) due to premature death using the prevalence approach, with disability weights (DWs) from the 2010 Global Burden of Disease (GBD) study. DALYs were calculated with R statistical software with the associated uncertainty intervals (UIs) computed by bootstrapping.

    Results

    A total of 1,005 (95% UI 797-1,213) DALYs were lost to ACE, which is 433 (95% UI 393-469) DALYs lost per 100,000 people. Twenty-six percent (113/100,000/year, 95% UI 106-117) of the DALYs were due to YLD and 74% (320/100,000/year, 95% UI 248-416) to YLL. Primary epilepsy accounted for fewer DALYs than secondary epilepsy (98 vs. 334 DALYs per 100,000 people). Those taking AEDs contributed fewer DALYs than those not taking AEDs (167 vs. 266 DALYs per 100,000 people). The proportion of people with ACE in remission per year was estimated at 11.0% in males and 12.0% in females, with highest rates in the 0-5year age group.

    Significance

    The DALYs for ACE are high in rural Kenya, but less than the estimates of 2010 GBD study. Three-fourths of DALYs resulted from secondary epilepsy. Use of AEDs was associated with 40% reduction of DALYs. Improving adherence to AEDs may reduce the burden of epilepsy in this area.

  • 5. Kahlow, H.
    et al.
    Olivecrona, Magnus
    Umeå University, Faculty of Medicine, Department of Pharmacology and Clinical Neuroscience, Clinical Neuroscience.
    Surgical and hardware complications to vagal nerve stimulation for drug resistant epilepsy. A longitudinal single centre study of 143 patients2012In: Epilepsia, ISSN 0013-9580, E-ISSN 1528-1167, Vol. 53, no s5, p. 33-33Article in journal (Other academic)
  • 6. Ozanne, A.
    et al.
    Hällgren Graneheim, Ulla
    Umeå University, Faculty of Medicine, Department of Nursing.
    Ekstedt, G.
    Malmgren, K.
    Patient experiences of epilepsy surgery - a longitudinal qualitative study2014In: Epilepsia, ISSN 0013-9580, E-ISSN 1528-1167, Vol. 55, no Supplement 2, p. 174-174Article in journal (Other academic)
  • 7. Ozanne, Anneli
    et al.
    Hällgren Graneheim, Ulla
    Umeå University, Faculty of Medicine, Department of Nursing. Department of Health Sciences, University West, Trollhättan, Sweden.
    Ekstedt, Gerd
    Malmgren, Kristina
    Patients' expectations and experiences of epilepsy surgery - A population-based long-term qualitative study2016In: Epilepsia, ISSN 0013-9580, E-ISSN 1528-1167, Vol. 57, no 4, p. 605-611Article in journal (Refereed)
    Abstract [en]

    Objective: The aim of this prospective and population-based longitudinal study was to explore patients' expectations before surgery and their experiences both short and long term after epilepsy surgery.

    Methods: A national sample of adult patients answered open-ended questions preoperatively, 2 years after surgery and at a cross-sectional long-term follow-up (mean 13 years, standard deviation [SD] 1.85). The answers were analyzed by qualitative content analysis.

    Results: Eighty patients participated in the study. Before surgery, patients experienced a belief in a "normal" life; they hoped for reduction of seizures and medication, a richer social life, and more self-confidence. However, they also experienced anxiety of the unknown. They were afraid of the operation, of continued seizures, and of complications. At both postoperative follow-ups patients experienced increased independence. They had symptom reduction, felt relief from worries and fears, and felt that they had a new life. However, some patients experienced that the operation had changed their life to the worse due to both psychological and neurologic adverse effects, regardless of whether they had obtained seizure freedom or improvement.

    Significance: Positive experiences of epilepsy surgery dominated, both in the short and long term. However, attention must be paid to negative expectations before and negative experiences after surgery in order to provide individual support and information. This should increase the possibility for patients to have realistic hopes before surgery and to find coping strategies in the new life situation after surgery.

  • 8. Pugliatti, Maura
    et al.
    Beghi, Ettore
    Forsgren, Lars
    Umeå University, Faculty of Medicine, Pharmacology and Clinical Neuroscience, Neurology.
    Ekman, Mattias
    Sobocki, Patrik
    Estimating the cost of epilepsy in Europe: a review with economic modeling.2007In: Epilepsia, ISSN 0013-9580, E-ISSN 1528-1167, Vol. 48, no 12, p. 2224-2233Article in journal (Other academic)
  • 9.
    Wagner, Ryan G
    et al.
    Umeå University, Faculty of Medicine, Department of Public Health and Clinical Medicine. University of the Witwatersrand, MRC/Wits Rural PublicHealth & Health Transitions Research Unit (Agincourt), Johannesburg, South Africa.
    Bertram, M
    Gomez-Olive, F X
    Tollman, S
    Lindholm, Lars
    Umeå University, Faculty of Medicine, Department of Public Health and Clinical Medicine.
    Newton, C
    Hofman, K
    Health care utilization and out-of-pocket costs of people with epilepsy in rural South Africa: a cross-sectional survey2015In: Epilepsia, ISSN 0013-9580, E-ISSN 1528-1167, Vol. 56, p. 141-141Article in journal (Other academic)
1 - 9 of 9
CiteExportLink to result list
Permanent link
Cite
Citation style
  • apa
  • ieee
  • modern-language-association-8th-edition
  • vancouver
  • Other style
More styles
Language
  • de-DE
  • en-GB
  • en-US
  • fi-FI
  • nn-NO
  • nn-NB
  • sv-SE
  • Other locale
More languages
Output format
  • html
  • text
  • asciidoc
  • rtf