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  • 1.
    Burstedt, Marie S I
    et al.
    Umeå University, Faculty of Medicine, Department of Clinical Sciences, Ophthalmology.
    Sandgren, Ola
    Umeå University, Faculty of Medicine, Department of Clinical Sciences, Ophthalmology.
    Golovleva, Irina
    Umeå University, Faculty of Medicine, Department of Medical Biosciences.
    Wachtmeister, Lillemor
    Umeå University, Faculty of Medicine, Department of Clinical Sciences, Ophthalmology.
    Retinal function in Bothnia dystrophy. An electrophysiological study.2003In: Vision Research, ISSN 0042-6989, E-ISSN 1878-5646, Vol. 43, no 24, p. 2559-2571Article in journal (Refereed)
    Abstract [en]

    Using prolonged dark adaptometry, standard dark adaptation (DA) and prolonged DA full-field electroretinograms (ERGs), we analysed the retinal function in patients with Bothnia dystrophy (BD), a variant of recessive retinitis punctata albescens (RPA). A compromised rod and cone function, a likely dysfunction of the Müller cells, and indications of disturbed neuronal function of the inner retina, were found. With prolonged DA, a gradual increase in retinal sensitivity to light and an improvement of the ERG components occurred. The findings indicate a prolonged synthesis of photopigments, retardation of the visual process in the retinal pigment epithelium (RPE), and a loss of retinal cells, probably starting at a relatively early age in BD.

  • 2.
    Fagard, Jacqueline
    et al.
    Laboratoire Psychologie de la Perception (CNRS UMR 8158), Université Paris Descartes, Centre Biomédical des Saints Pères, 45 rue des Sts Pères, 75006 Paris, France.
    Sacco, Silvia
    Laboratoire Psychologie de la Perception (CNRS UMR 8158), Université Paris Descartes, Centre Biomédical des Saints Pères, 45 rue des Sts Pères, 75006 Paris, France.
    Yvenou, Chantal
    Hôpital Sud Rennes, Maternité, 16 Boulevard de Bulgarie, 35203 Rennes Cedex 2, France.
    Domellöf, Erik
    Umeå University, Faculty of Social Sciences, Department of Psychology.
    Kieffer, Virginie
    Institut Gustave Roussy, Département de cancérologie de l’enfant et de l’adolescent, 39 rue Camille Desmoulins, 94805 Villejuif, France.
    Tordjman, Sylvie
    Laboratoire Psychologie de la Perception (CNRS UMR 8158), Université Paris Descartes, Centre Biomédical des Saints Pères, 45 rue des Sts Pères, 75006 Paris, France.
    Moutard, Marie-Laure
    Hôpital Armand Trousseau, Service de Neuropédiatrie, 26, avenue du Docteur Arnold-Netter, 75012 Paris, France.
    Mamassian, Pascal
    Laboratoire Psychologie de la Perception (CNRS UMR 8158), Université Paris Descartes, Centre Biomédical des Saints Pères, 45 rue des Sts Pères, 75006 Paris, France.
    The role of the corpus callosum in the perception of reversible figures in children2008In: Vision Research, ISSN 0042-6989, E-ISSN 1878-5646, Vol. 48, p. 2451-2455Article in journal (Refereed)
    Abstract [en]

    To test the role of interhemispheric competition through the corpus callosum in the perceptual alternation of reversible figures, we compared children with callosal pathology and typically developing children on a bistable stimulus task. The children with corpus callosum pathology reported significantly less changes of percepts per minute than the age-matched typically developing children. In addition, older typically developing children reported significantly more changes of percepts than the younger ones. These results support the hypothesis that the rate of reversal between two interpretations of a bistable stimulus may be partly mediated by the corpus callosum.

  • 3.
    Mönestam, Eva
    et al.
    Umeå University, Faculty of Medicine, Department of Clinical Sciences, Ophthalmology.
    Andersson, Mikael
    Umeå University, Faculty of Medicine, Department of Clinical Sciences, Ophthalmology.
    Åström, Siv
    Umeå University, Faculty of Medicine, Department of Clinical Sciences, Ophthalmology.
    Associations between subjective and objective visual function in patients with unilateral macular holes2008In: Vision Research, ISSN 0042-6989, E-ISSN 1878-5646, Vol. 48, no 1, p. 104-108Article in journal (Refereed)
    Abstract [en]

    Forty-six patients with uniocular macular holes and unaffected, fellow eyes were studied to evaluate inter- and intraocular associations between various objective tests of visual function and perceived visual ability. The affected eye had significant associations between visual acuity (VA) and the fovea threshold test, but for the fellow eye only VA and low-contrast VA 10% were associated. The reduction in visual acuity under low-contrast conditions relative to high-contrast did not differ between the affected eye and the healthy eye. Subjective visual ability seems to depend more on the visual acuity of the affected eye than the healthy eye.

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