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  • 151. Wehling, Eike
    et al.
    Naess, Halvor
    Wollschlaeger, Daniel
    Hofstad, Hakon
    Bramerson, Annika
    Bende, Mats
    Nordin, Steven
    Umeå universitet, Samhällsvetenskapliga fakulteten, Institutionen för psykologi.
    Olfactory dysfunction in chronic stroke patients2015Ingår i: BMC Neurology, ISSN 1471-2377, E-ISSN 1471-2377, Vol. 15, artikel-id 199Artikel i tidskrift (Refereegranskat)
    Abstract [en]

    Background: The aim of the study was to investigate odor identification performance in patients one year after hospital admittance due to stroke. Predictors for olfactory dysfunction were investigated as well as self-reported olfactory function and pleasantness of olfactory items.

    Methods: A 1-year prospective study was performed. Stroke location, classification and comorbidities were registered at hospital admission. One year after admission, olfactory function was assessed using standardized olfactory methods (screening for loss of detection sensitivity and an odor identification test). A group of matched controls was derived from a population-based study to compare odor identification performance between groups. Patients were asked for their personal judgment regarding their olfactory function and pleasantness of odorous items. In addition, global cognitive function and symptoms of depression were assessed.

    Results: A total of 78 patients were enrolled (46 males, 32 females; mean age 68 years) of which 28.2 % exhibited reduced olfactory function (hyposmia) and 15.4 % exhibited loss of olfactory function (10.3 % functional anosmia, 5.1 % complete anosmia). Patients showed significantly lower olfactory performance compared to age- and sex-mated matched controls. Predictors of impaired olfactory function were age and NIHSS score. Self-reports indicated no significant differences between patients with normal olfactory function and those with reduced function. Yet, patients having an olfactory dysfunction rated odorous items as significantly less pleasant compared to patients without dysfunction.

    Conclusions: Olfactory dysfunction seems to occur frequently after stoke even one year after initial admission. The deficits seem to relate to hyposmia and functional anosmia, and less to a complete loss of smell sensitivity.

  • 152.
    Wehling, Eike
    et al.
    Department of Biological and Medical Psyvhology, University of Bergen, Norway, Kavli Research Centre for Aging and Dementia, Haraldsplass Deaconesses Hospital, Bergen, Norway.
    Nordin, Steven
    Umeå universitet, Samhällsvetenskapliga fakulteten, Institutionen för psykologi.
    Espeseth, Thomas
    Department of Psychology, University of Oslo, Norway.
    Reinvang, Ivar
    Department of Psychology, University of Oslo, Sweden.
    Lundervold, Astri J.
    Haraldsplass Deaconesses Hospital, Bergen, Norway.
    Unawareness of olfactory dysfunction and its association with cognitive functioning in middle aged and old adults2011Ingår i: Archives of clinical neuropsychology, ISSN 0887-6177, E-ISSN 1873-5843, Vol. 26, nr 3, s. 260-269Artikel i tidskrift (Refereegranskat)
    Abstract [en]

    The objective of this study was (a) to investigate the accordance of self-reported and objectively assessed olfactory functioning and (b) to compare performance on cognitive tests of individuals unaware of their olfactory dysfunction with individuals aware of their olfactory status. Two hundred forty participants, constituting two age groups, were evaluated with the Scandinavian Odor Identification Test, a question of self-evaluated olfactory function, tests of cognitive function, and a memory questionnaire. The proportion of individuals being unaware of an olfactory dysfunction was high in both middle aged (86%) and old (78%) participants. Performance on neuropsychological tests showed that persons unaware of their olfactory dysfunction performed poorer on tests of verbal learning and memory and attention/processing speed compared to individuals aware of a normal olfactory status as well as individuals aware of their olfactory dysfunction. The clinical relevance of unawareness of olfactory dysfunction, as suggested earlier, needs further investigation and stresses the need of an extensive multi-modal and longitudinal assessment of unawareness of sensory and cognitive function to learn more about the facets of the concept of unawareness.

  • 153.
    Öhman, Lena
    et al.
    Umeå universitet, Samhällsvetenskaplig fakultet, Psykologi.
    Nordin, Steven
    Umeå universitet, Samhällsvetenskaplig fakultet, Psykologi.
    Bergdahl, Jan
    Umeå universitet, Samhällsvetenskaplig fakultet, Psykologi.
    Slunga Birgander, Lisbeth
    Umeå universitet, Medicinsk fakultet, Folkhälsa och klinisk medicin, Yrkes- och miljömedicin.
    Stigsdotter-Neely, Anna
    Umeå universitet, Samhällsvetenskaplig fakultet, Psykologi.
    Cognitive function in outpatients with perceived chronic stress2007Ingår i: Scand J Work Environ Health, ISSN 0355-3140, Vol. 33, nr 3, s. 223-232Artikel i tidskrift (Refereegranskat)
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