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  • 51.
    Aasa, Ulrika
    et al.
    Umeå University, Faculty of Medicine, Department of Community Medicine and Rehabilitation, Physiotherapy. Umeå University, Faculty of Social Sciences, Umeå Sport Sciences Center.
    Svartholm, Ivar
    Umeå University, Faculty of Medicine, Department of Community Medicine and Rehabilitation, Physiotherapy.
    Andersson, Fredrik
    Umeå University, Faculty of Medicine, Department of Community Medicine and Rehabilitation, Physiotherapy.
    Berglund, Lars
    Umeå University, Faculty of Medicine, Department of Community Medicine and Rehabilitation, Physiotherapy. Umeå University, Faculty of Social Sciences, Umeå Sport Sciences Center.
    Injuries among weightlifters and powerlifters: a systematic review2017In: British Journal of Sports Medicine, ISSN 0306-3674, E-ISSN 1473-0480, Vol. 51, no 4, p. 211-219Article in journal (Refereed)
    Abstract [en]

    Background Olympic weightlifting and powerlifting are two sports that expose the body to great forces. Injury characteristics have not been systematically reviewed for these two growing sports.

    Objective The purpose of this study was to systematically review the literature regarding various definitions of injuries used, injury localisation, the prevalence and incidence of injuries and the associated risk factors for injuries in weightlifting and powerlifting.

    Design Systematic review.

    Data sources Five databases, PubMed, MEDLINE, SPORTDiscus, Scopus and Web of Science, were searched between 9 March and 6 April 2015.

    Eligibility criteria for selecting studies Studies assessing injury incidence and prevalence in Olympic weightlifting and powerlifting were included. The Quality assessment tool for observational cohort and cross-sectional studies was used to assess methodological quality.

    Results 9 studies were included in the review. Injury was defined fairly consistently across studies. Most studies were of low methodological quality. The spine, shoulder and the knee were the most common injury localisations in both sports. The injury incidence in weightlifting was 2.4–3.3 injuries/1000 hours of training and 1.0–4.4 injuries/1000 hours of training in powerlifting. Only one retrospective study had analysed possible risk factors.

    Summary/conclusions The risk of injury in both sports were similar to other non-contact sports also requiring strength/power, but low compared to contact sports. The severity of injuries differed in the included studies. Since little has been studied regarding possible risk factors to injuries, further research is therefore warranted to explain why athletes get injured and how to prevent injuries.

    Trial registration number PROSPERO CRD42015014805.

  • 52.
    Aasa, Ulrika
    et al.
    Umeå University, Faculty of Medicine, Department of Community Medicine and Rehabilitation, Physiotherapy.
    Westerståhl, Maria
    Institutionen för laboratoriemedicin avd för klinisk fysiologi Karolinska institutet .
    Barnekow-Bergkvist, Margareta
    Umeå University, Faculty of Medicine, Department of Public Health and Clinical Medicine, Epidemiology and Global Health.
    Jansson, Eva
    Institutionen för laboratoriemedicin avd för klinisk fysiologi Karolinska institutet .
    Hälsoresan till medelåldern2011In: Svensk Idrottsforskning: Organ för Centrum för Idrottsforskning, ISSN 1103-4629, no 2, p. 4p. 40-43Article in journal (Other academic)
    Abstract [sv]

    Vad är viktigast för att få en god hälsa som vuxen? Sedan 1974 har vi följt samma personer från 16 års ålder in i medelåldern och studerat deras hälsa från flera olika synvinklar. Nu pågår den tredje mätomgången.

  • 53.
    Aasa, Ulrika
    et al.
    Umeå University, Faculty of Medicine, Department of Community Medicine and Rehabilitation, Physiotherapy.
    Wiitavaara, Birgitta
    Högskolan i Gävle.
    Personalens hälsa och arbetsmiljö2009In: Prehospital akutsjukvård / [ed] Björn-Ove Suserud och Leif Svensson, Stockholm: Liber, 2009, p. 33-38Chapter in book (Other (popular science, discussion, etc.))
  • 54.
    Aasa, Ulrika
    et al.
    Umeå University, Faculty of Medicine, Department of Community Medicine and Rehabilitation, Physiotherapy.
    Ängquist, Karl-Axel
    Umeå University, Faculty of Medicine, Department of Surgical and Perioperative Sciences. Umeå University, Faculty of Medicine, Department of Surgical and Perioperative Sciences, Surgery.
    Barnekow-Bergkvist, Margareta
    The effects of a 1-year physical exercise programme on development of fatigue during a simulated ambulance work task.2008In: Ergonomics, ISSN 0014-0139, E-ISSN 1366-5847, Vol. 51, no 8, p. 1179-94Article in journal (Refereed)
    Abstract [en]

    The aim of the study was to evaluate the effects of individually prescribed physical exercise programmes on development of fatigue during the carrying of a loaded stretcher up and down the stairs. Nineteen ambulance personnel performed the training for 1 year. Testing occurred before and after 1 year of the training. Both the training group (n = 19) and the control group (n = 15) were assessed for physical capacity and lactate concentration in blood and ratings of perceived exertion during carrying a stretcher on the stairs. When comparisons were made between those who had been training three times/week for 1 year and the control group, lactate concentration was significantly decreased. In conclusion, markers of fatigue during stretcher carrying can be reduced by the use of individually prescribed physical exercise programmes.

  • 55.
    Aase, Zandra
    Umeå University, Faculty of Arts, Department of language studies.
    Collage etnolingüístico en la poesía mapuche2015Independent thesis Basic level (degree of Bachelor), 10 credits / 15 HE creditsStudent thesis
    Abstract [en]

    This study has the goal to analyze the strategy used by the Mapuche poets so called collage ethno-linguistic and to reveal how it is used by their authors. Given that we will analyze poems in which its authors are Mapuche, we want to investigate whether their own worldview, culture and religiosity is reflected into the poem.

     

    For this purpose we will analyze three poems written by the Chilean Mapuche poets in order to have the proper overview of their lyrical poetry. Those poems are “Huida”, by Maribel Mora Curriao, “Quila” from Pedro Alonzo Retamal, and “Desde aquí” from the poet Jaqueline Caniguán.  On the other hand we will also inquire into other papers of several researchers that have studied the ethno-literature, such as Iván and Hugo Carrasco Muñoz and the paper written by the researcher Maria Ester Greve  in order to support our investigation.

     

     

    Key words: ethnolinguistic collage, Maribel Mora Curriao, Pedro Alonzo Retamal, Jaqueline Caniguán, Mapuche poetry, world view, Mapuche religiosity. 

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  • 56.
    Aasted, Evelina
    et al.
    Umeå University, Faculty of Medicine, Department of Community Medicine and Rehabilitation, Physiotherapy.
    Danielsson, Johanna
    Umeå University, Faculty of Medicine, Department of Community Medicine and Rehabilitation, Physiotherapy.
    Den laddade gymspegeln: - Unga styrketränande kvinnors förhållande till speglar på gymmet2015Independent thesis Basic level (degree of Bachelor), 10 credits / 15 HE creditsStudent thesis
    Abstract [sv]

    Introduktion: Spegeln har en lång historia som en väsentlig del i rehabilitering och används med varierade syften inom olika fysioterapeutiska områden. Forskning har dock visat att träning i speglade miljöer kan ge en negativ påverkan på självkänslan. Det är därför av stor vikt för fysioterapeuter att vara medveten om och inventera speglarnas olika påverkan.

    Syfte: Syftet med studien var att utforska unga styrketränande kvinnors förhållande till speglar på gymmet och hur det påverkar deras kroppsuppfattning och självkänsla.

    Metod: Studien baseras på kvalitativa intervjuer med fyra unga kvinnor. Inkluderingskriterierna är var unga styrketränande kvinnor i åldrarna 20-25 år. Intervjuguiden som användes är var semistrukturerade och analysmetoden är var Grounded Theory.

    Resultat: Resultatet av analysen utmynnade i kärnkategorin ”Den laddade gymspegeln” och kategorier med tillhörande underkategorier. De kategorier som formulerades fram var: ”Speglad trygghet och motivation”, ”Reflekterad osäkerhet”, ”Den dömande gymspegeln”, ”Gymspegeln skapar bidrar till stressig gymmiljö”, ”Gymspegeln som förstärkare av krävande kroppsideal”. Som sista steg i analysen skapades en modell.

    Konklusion: Unga styrketränande kvinnor upplevdeer att det finns en såväl positiv som negativ laddning med speglar på gymmet. Det var viktigt med speglar ur teknik- och skadepreventionssyfte. Samtidigt bidrog den speglade miljön till ett jämförande och ökat dömande. Det är fördelaktigt för fysioterapeuter att vara medvetna om speglarnas påverkan på unga styrketränande kvinnors självkänsla och kroppsuppfattning. Mer forskning krävs inom området.

  • 57.
    Aava Olsson, Emma
    et al.
    Umeå University, Faculty of Social Sciences, Umeå School of Business and Economics (USBE), Business Administration.
    Björnehall, Oskar
    Umeå University, Faculty of Social Sciences, Umeå School of Business and Economics (USBE), Business Administration.
    Förändring i pandemitider: En kvalitativ studie om covid-19s påverkan på svenska industriföretags arbete med riskidentifiering och begränsningsstrategier2023Independent thesis Advanced level (professional degree), 20 credits / 30 HE creditsStudent thesis
    Abstract [sv]

    Det här examensarbetet utforskar hur covid-19 har förändrat sättet för industriföretag i norra Sverige att arbeta med supply chain risk management, där fokus ligger på de två processerna riskidentifiering och begränsningsstrategier. Supply chain risk management är ett växande ämne som fått allt mer uppmärksamhet hos forskare. Fortsättningsvis har existerande litteratur visat att covid-19 fick stora effekter på företags försörjningskedjor i form av störningar och att förändringar inom arbetet med risker tagit sin början. Däremot saknas forskning på hur förändringarna fortsatt utvecklas fram till idag som en konsekvens av pandemin. Därav saknas ett helhetsperspektiv över vilka förändringar som har skett från innan covid-19 fram tills idag. Vidare har existerande litteratur framhållit riskidentifiering och begränsningsstrategier som de två mest kritiska processerna i supply chain risk management och därför valde vi att rikta in studien på just dem. Fortsättningsvis har norra Sverige valts som geografisk kontext för studien eftersom det hittills varit ett outforskat område. Dessutom har industriföretag varit föremål för studien då de ofta har globala och komplexa försörjningskedjor. Syftet med den här studien är att undersöka och skapa en djupare förståelse för hur industriföretag belägna i norra Sverige har förändrat arbetet med riskidentifiering och riskbegränsning inom processen supply chain risk management från tidsperioden innan covid-19, under covid-19 och tiden efter covid-19. I studien genomfördes 6 semi-strukturerade intervjuer med respondenter från olika industriföretag i norra Sverige. En kvalitativ metod valdes för den här studien, tillsammans med ett induktivt synsätt, vilket har gett oss flera insikter om hur industriföretag förändrat sitt sätt att arbeta med risker från innan covid-19 till efter. 

    För det första indikerar våra resultat att en förändring som har skett är att förståelsen har ökat under covid-19, för hur pandemier fungerar och vilka konsekvenser en pandemi kan orsaka för företagens verksamhet, från att knappt ha existerat innan covid-19. Det här medförde att företagen implementerade en mer strukturerad riskidentifiering och började arbeta mer konsekvent med riskidentifiering under covid-19. För det andra observerades en förändring där en övergång skett från fysiska riskidentifierings möten till digitala riskidentifierings möten, vilket berodde på social distansering. Samtidigt som mötensfrekvensen ökade för att kunna identifiera kritiska komponenter för verksamheten. För det tredje kunde resultatet visa att det har skett en förändring från att företag haft liten kunskap om leverantörer och avancerade datasystem under covid-19, till att de efter covid-19 införde verktyg för att förstå leverantörer tillsammans med avancerade datasystem. För det fjärde visar resultatet att företagen arbetade med leverantörer utifrån just-in-time innan covid-19, vilket förändrades under covid-19 då företagen blev medvetna om just-in-times utsatthet. För det femte påvisar resultatet att företag arbetade med endast en eller ett fåtal leverantörer innan covid-19 vilket förändrades under covid-19 då second sourcing infördes som begränsningsstrategi. För det sjätte användes inte strategin säkerhetslager under covid-19, men infördes efter covid-19. Slutligen bidrar studien med praktiska bidrag till industriföretag och personal. För det första, framkommer vikten av att ha kunskap och struktur för riskidentifiering och begränsningsstrategier hos industriföretag. För det andra, behöver företag arbeta mer med samarbeten och öka sin förståelse för olika intressenter för att hantera risker. För det tredje bör industriföretag införa säkerhetslager och second-sourcing för att hantera risker. För det fjärde, bör industriföretags personal få ökad möjlighet till information och kunskap om risker och hur dessa hanteras. Vårt teoretiska bidrag skapar en helhetsbild för hur riskidentifiering och begränsningsstrategier har förändrats på grund av covid-19 inom geografiska kontexten norra Sverige. Därutöver har studien bidragit med kvalitativ forskning på ämnet och gett en ökad förståelse för att det behövs mer forskning gällande makro-riskers påverkan på företags verksamhet och försörjningskedja. 

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  • 58.
    Aavik, Ida
    Umeå University, Faculty of Science and Technology, Department of Applied Physics and Electronics.
    Onboarding New Users for Initial Creation of Photo Book in Mobile Application2024Independent thesis Advanced level (professional degree), 20 credits / 30 HE creditsStudent thesis
    Abstract [en]

    Photography holds great significance by capturing memories and sharing stories. Today, the average user has around 2,000 photos on their smartphone, many of which go unnoticed. Once Upon is a mobile application launched in 2017, where users can create photo books to collect their memories in a physical book. Observations and previous data from Once Upon show that new users encounter certain challenges when creating their first photo book with the application. This has sparked interest in exploring how onboarding can be used to help new users. Onboarding is a broad term that includes introducing users to a new product or service.

    This study followed the Design Thinking process to create a prototype of an onboarding process that facilitates understanding for new users how to get started with creating their first photo book using the Once Upon mobile application. In the first phase, Empathize, research methods were conducted to identify how users interact with the Once Upon mobile application. The data was further analyzed in order to narrow down the topic and define the problems in the Define phase, employing methods such as personas, user flow diagrams and mind mapping. Subsequently, ideas began to be generated in the next phase, Ideate, where How Might We statements were formulated. These were utilized in two workshops for brainstorming, and then contributed to the initial sketching of different design proposals. The last two phases, Prototype and Test, were performed iteratively to produce prototypes and test them with usability testing.

    It was observed that new users experienced some challenges when creating a photo book for the first time in the application. Among other things, they lacked inspiration, looked in the wrong place for certain functions or did not know how to start from scratch. With this, the focus was placed on the onboarding flow being about introducing users to creating their first photo book with the Once Upon mobile application. Different strategies and types of onboarding had been analyzed, and then some that were deemed suitable for the application were chosen to proceed with. During the tests of the prototypes, a flow was finally chosen that the participants appreciated the most. The result contributed to helping new users get started and get inspired to create their first photo book with the Once Upon mobile application, through the creation of a design proposal of an onboarding process.

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  • 59. Aazh, Hashir
    et al.
    Knipper, Marlies
    Danesh, Ali A.
    Cavanna, Andrea E.
    Andersson, Linus
    Umeå University, Faculty of Social Sciences, Department of Psychology.
    Paulin, Johan
    Umeå University, Faculty of Social Sciences, Department of Psychology.
    Schecklmann, Martin
    Heinonen-Guzejev, Marja
    Moore, Brian C. J.
    Insights from the Third International Conference on Hyperacusis: Causes, Evaluation, Diagnosis, and Treatment2018In: Noise & Health, ISSN 1463-1741, E-ISSN 1998-4030, Vol. 20, no 95, p. 162-170Article in journal (Refereed)
    Abstract [en]

    Background: Hyperacusis is intolerance of certain everyday sounds that causes significant distress and impairment in social, occupational, recreational, and other day-to-day activities. 

    Objective: The aim of this report is to summarize the key findings and conclusions from the Third International Conference on Hyperacusis.

    Topics covered: The main topics discussed comprise (1) diagnosis of hyperacusis and audiological evaluations, (2) neurobiological aspect of hyperacusis, (3) misophonia, (4) hyperacusis in autism spectrum disorder, (5) noise sensitivity, (6) hyperacusis-related distress and comorbid psychiatric illness, and (7) audiologist-delivered cognitive behavioral therapy for hyperacusis.

    Conclusions: Implications for research and clinical practice are summarised.

  • 60. Abafe, Ovokeroye A.
    et al.
    Späth, Jana
    Umeå University, Faculty of Science and Technology, Department of Chemistry.
    Fick, Jerker
    Umeå University, Faculty of Science and Technology, Department of Chemistry.
    Jansson, Stina
    Umeå University, Faculty of Science and Technology, Department of Chemistry.
    Buckley, Chris
    Stark, Annegret
    Pietruschka, Bjoern
    Martincigh, Bice S.
    LC-MS/MS determination of antiretroviral drugs in influents and effluents from wastewater treatment plants in KwaZulu-Natal, South Africa2018In: Chemosphere, ISSN 0045-6535, E-ISSN 1879-1298, Vol. 200, p. 660-670Article in journal (Refereed)
    Abstract [en]

    South Africa has the largest occurrence of the human immune deficiency virus (HIV) in the world but has also implemented the largest antiretroviral (ARV) treatment programme. It was therefore of interest to determine the presence and concentrations of commonly used antiretroviral drugs (ARVDs) and, also, to determine the capabilities of wastewater treatment plants (WWTPs) for removing ARVDs. To this end, a surrogate standard based LC-MS/MS method was optimized and applied for the detection of thirteen ARVDs used in the treatment and management of HIV/acquired immune deficiency syndrome (HIV/AIDS) in two major and one modular WWTP in the eThekwini Municipality in KwaZulu-Natal, South Africa. The method was validated and the detection limits fell within the range of 2–20 ng L−1. The analytical recoveries for the ARVDs were mainly greater than 50% with acceptable relative standard deviations. The concentration values ranged from <LOD – 53000 ng L−1 (influent), <LOD – 34000 ng L−1 (effluent) in a decentralized wastewater treatment facility (DEWATS); <LOD – 24000 ng L−1 (influent), <LOD – 33000 ng L−1 (effluent) in Northern WWTP and 61–34000 ng L−1 (influent), <LOD – 20000 ng L−1 (effluent) in Phoenix WWTP. Whilst abacavir, lamivudine and zidovudine were almost completely removed from the effluents, atazanavir, efavirenz, lopinavir and nevirapine persisted in the effluents from all three WWTPs. To estimate the ecotoxicological risks associated with the discharge of ARVDs, a countrywide survey focussing on the occurrence of ARVDs in WWTPs, surface and fresh water bodies, and aquatic organisms, is necessary.

  • 61.
    Abai Luelseged, Solomon
    Umeå University, Faculty of Social Sciences, Department of applied educational science.
    Samarbete mellan studiehandledare och ämneslärare: En kvalitativ studie om samarbetet mellan studiehandledare och ämneslärare kring studiehandledning på modersmålet2019Independent thesis Basic level (professional degree), 10 credits / 15 HE creditsStudent thesis
    Abstract [sv]

    Studiehandledning på modersmålet är ett sätt att stödja nyanlända elevers kunskapsutveckling i alla ämnen samtidigt som de lär sig det svenska språket. Studiehandledning på modersmålet har funnits i förordningarna för grund- och gymnasieskolan sedan 1997. Ämneslärarens och studiehandledarens roll är av stor vikt när det gäller studiehandledning på modersmålet. Ämneslärare planerar undervisningen och studiehandledaren följer planeringen.

    Syftet med denna studie är att undersöka samarbetet mellan ämneslärare och studiehandledare, vad som framträder i studiehandledarens respektive ämneslärarens yrkesroll och hur ämnesläraren och studiehandledaren beskriver samarbetet när det gäller studiehandledning på modersmålet. Dessutom lyfts vilken betydelse samarbetet har för nyanlända elever i skolan.

    Studien har genomförts på en gymnasieskola som undervisar nyanlända elever och informanterna är ämneslärare och studiehandledare. Sammanlagt genomfördes sex intervjuer: tre ämneslärare och tre studiehandledare deltog.

    Resultaten av denna studie visar att ämneslärare och studiehandledare samarbetar för att stötta nyanlända elever i deras lärande. Det visar att tidsbristen är ett hinder för samarbetet och att kompetensutveckling inom området studiehandledning på modersmålet är en förutsättning för samarbetet mellan ämneslärare och studiehandledare.

  • 62. Abalaka, J. L.
    et al.
    Ottosson, Ulf
    Tende, Talatu
    Larson, Keith W.
    Rock Firefinch Lagonosticta sanguinodorsalis in the Mandara Mountains, north-east Nigeria: a new subspecies?2010In: African Bird Club Bulletin, ISSN 1352-481X, Vol. 17, no 2, p. 210-211Article in journal (Refereed)
    Abstract [fr]

    L’Amarante des rochers Lagonosticta sanguinodorsalis dans les Monts Mandara, Nigeria du sud-est: une nouvelle sous-espèce ? Nous fournissons une description d’un mâle et d’une femelle, ainsi que desphotos d’un mâle, d’un amarante capturé dans les Monts Mandara, au nord-est du Nigeria. Le plumage et le cri de cet amarante sont identiques à ceux de l’Amarante des rochers Lagonosticta sanguinodorsalis, une espèce précédemment rapportée de la zone, excepté que le mâle n’a pas la couronne grise typique de l’espèce. Des travaux supplémentaires sur le terrain sont nécessaires pour déterminer s’il agit d’un individu aberrant ou d’une population de l’Amarante des rochers morphologiquement distincte.

  • 63.
    Abassi, Marwa
    Umeå University, Faculty of Medicine, Department of Pharmacology and Clinical Neuroscience, Pharmacology.
    Effektivitet av kognitiv beteendeterapi vid Irritable bowel syndrome2019Independent thesis Basic level (professional degree), 10 credits / 15 HE creditsStudent thesis
  • 64. Abat, F
    et al.
    Alfredson, Håkan
    Umeå University, Faculty of Medicine, Department of Community Medicine and Rehabilitation, Sports medicine. Alfredson Tendon Clinic Inc, Umeå, Sweden; Pure Sports Medicine Clinic, ISEH, UCLH, London, UK.
    Cucchiarini, M
    Madry, H
    Marmotti, A
    Mouton, C
    Oliveira, J M
    Pereira, H
    Peretti, G M
    Spang, Christoph
    Umeå University, Faculty of Medicine, Department of Integrative Medical Biology (IMB), Anatomy.
    Stephen, J
    van Bergen, C J A
    de Girolamo, L
    Current trends in tendinopathy: consensus of the ESSKA basic science committee. Part II2018In: Journal of experimental orthopaedics, ISSN 2197-1153, Vol. 5, no 38Article in journal (Refereed)
    Abstract [en]

    The treatment of painful chronic tendinopathy is challenging. Multiple non-invasive and tendon-invasive methods are used. When traditional non-invasive treatments fail, the injections of platelet-rich plasma autologous blood or cortisone have become increasingly favored. However, there is little scientific evidence from human studies supporting injection treatment. As the last resort, intra- or peritendinous open or endoscopic surgery are employed even though these also show varying results. This ESSKA basic science committee current concepts review follows the first part on the biology, biomechanics and anatomy of tendinopathies, to provide a comprehensive overview of the latest treatment options for tendinopathy as reported in the literature.

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  • 65.
    Abat, F.
    et al.
    Department of Orthopaedic Sports Medicine, ReSport Clinic, Passeig Fabra i Puig 47, Barcelona, Spain.
    Alfredson, Håkan
    Umeå University, Faculty of Medicine, Department of Community Medicine and Rehabilitation, Sports Medicine. Alfredson Tendon Clinic Inc, Umeå, Sweden; Pure Sports Medicine Clinic, ISEH, UCLH, London, United Kingdom.
    Cucchiarini, M.
    Molecular Biology, Center of Experimental Orthopaedics, Saarland University Medical Center, Kirrbergerstr Bldg 37, Homburg/Saar, Germany.
    Madry, H.
    Lehrstuhl für Experimentelle Orthopädie und Arthroseforschung, Universität des Saarlandes, Gebäude 37, Kirrbergerstr 1, Homburg, Germany.
    Marmotti, A.
    Department of Orthopaedics and Traumatology, San Luigi Gonzaga Hospital, Orbassano, University of Turin, Turin, Italy.
    Mouton, C.
    Department of Orthopedic Surgery, Clinique d’Eich-Centre Hospitalier de Luxembourg, 76, rue d’Eich, Luxembourg, Luxembourg.
    Oliveira, J.M.
    3B’s Research Group – Biomaterials, Biodegradables and Biomimetics, University of Minho, Headquarters of the European Institute of Excellence on Tissue Engineering and Regenerative Medicine, AvePark, Zona Industrial da Gandra, GMR, Barco, Portugal; ICVS/3B’s - PT Government Associate Laboratory, Braga, Guimarães, Portugal.
    Pereira, H.
    3B’s Research Group University of Minho, ICVS/3B’s–PT Government Associate Laboratory, Braga, Guimarães, Portugal; Orthopedic Department Centro Hospitalar Póvoa de Varzim, Vila do Conde, Portugal; Ripoll y De Prado Sports Clinic – FIFA Medical Centre of Excellence, Madrid, Murcia, Spain.
    Peretti, G.M.
    IRCCS Istituto Ortopedico Galeazzi, Department of Biomedical Sciences for Health, University of Milan, Milan, Italy.
    Romero-Rodriguez, D.
    Department of Physical Therapy and Sports Rehabilitation, ReSport Clinic Barcelona, Barcelona, Spain; EUSES Sports Science, University of Girona, Girona, Spain.
    Spang, Christoph
    Umeå University, Faculty of Medicine, Department of Integrative Medical Biology (IMB), Anatomy.
    Stephen, J.
    Fortius Clinic, 17 Fitzhardinge St, London, United Kingdom; The Biomechanics Group, Department of Mechanical Engineering, Imperial College, London, United Kingdom.
    van Bergen, C.J.A.
    Department of Orthopedic Surgery, Amphia Hospital Breda, Breda, Netherlands.
    de Girolamo, L.
    Orthopaedic Biotechnology Laboratory, Galeazzi Orthopaedic Institute, Milan, Italy.
    Current trends in tendinopathy: consensus of the ESSKA basic science committee. Part I: biology, biomechanics, anatomy and anexercise-based approach2017In: Journal of Experimental Orthopaedics, E-ISSN 2197-1153, Vol. 4, no 1, article id 18Article, review/survey (Refereed)
    Abstract [en]

    Chronic tendinopathies represent a major problem in the clinical practice of sports orthopaedic surgeons, sports doctors and other health professionals involved in the treatment of athletes and patients that perform repetitive actions. The lack of consensus relative to the diagnostic tools and treatment modalities represents a management dilemma for these professionals. With this review, the purpose of the ESSKA Basic Science Committee is to establish guidelines for understanding, diagnosing and treating this complex pathology.

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  • 66.
    Abat, Ferran
    et al.
    ReSport Clinic Barcelona, Blanquerna-Ramon Llull University School of Health Science, Rosselló, Barcelona, Spain.
    Alfredson, Håkan
    Umeå University, Faculty of Medicine, Department of Community Medicine and Rehabilitation, Section of Sports Medicine.
    Sonosurgery ultrasound-guided arthroscopic shaving for the treatment of patellar tendinopathy when conservative treatment fails2023In: Anterior knee pain and patellar instability / [ed] Vicente Sanchis-Alfonso, Cham: Springer Nature, 2023, 3, p. 403-413Chapter in book (Refereed)
    Abstract [en]

    Proximal patellar Tendinopathy, commonly denominated as Jumper´s Knee, is widely considered to be a challenge to treat (Abat et al. in J Exp Orthop. 3:34, 2016). The treatment of patellar tendinopathy focuses on reducing if not eliminating the pain and improving function. At present, there are a several distinct treatments oriented to that end, and a “gold-standard” treatment might be in sight. (Abat F, Alfredson H, Cucchiarini M, Madry H, Marmotti A, Mouton C, Oliveira JM, Pereira H, Peretti GM, Spang C, Stephen J, van Bergen CJA, de Girolamo L. Current trends in tendinopathy: consensus of the ESSKA basic science committee. Part II: treatment options. J Exp Orthop. 2018 Sep 24;5(1):38. https://doi.org/10.1186/s40634-018-0145-5.)

  • 67. Abat, Ferran
    et al.
    Alfredson, Håkan
    Umeå University, Faculty of Medicine, Department of Community Medicine and Rehabilitation, Section of Sports Medicine.
    Campos, Jocelio
    Planells, Gabriel
    Torras, Jordi
    Madruga-Parera, Marc
    Rodriguez-Baeza, Alfonso
    Ultrasound-guided versus blind interventions in patellar tendon lesions: a cadaveric study2021In: Skeletal Radiology, ISSN 0364-2348, E-ISSN 1432-2161, Vol. 50, no 5, p. 967-972Article in journal (Refereed)
    Abstract [en]

    Purpose: The present study aims to analyze the accuracy of injections aimed to hit the proximal and depth part of the patellar tendon "target point" in patellar tendinopathy, comparing ultrasound-guided or non-ultrasound-guided (blind) injections.

    Methods: A cadaver randomized study was carried out. Injections were performed under ultrasound control, as well as blinded. There were 26 knees from fresh cadavers and injections were placed by 26 practitioners with experience in the use of musculoskeletal ultrasound and injection treatment. Each participant performed 6 ultrasound-guided and 6 blind punctures in different cadaveric specimens. This provided 312 injections that were analyzed in 2 different anatomical cuts, thus providing a database of 624 measurements for statistical analysis.

    Results: Statistically significant differences were observed (p < 0.0001) in the distance from the target point between the ultrasound-guided and the non-guided infiltrations. The "unguided" injections were considered to have been performed on average 10 mm away from the target point compared to the "ultrasound-guided" injections. The ultrasound-guided injections obtained an accuracy of 74.36% while the "non-ultrasound-guided" injections obtained an accuracy of 11.54% (p < 0.0001).

    Conclusion: The use of ultrasound to guide the positioning of injections on the dorsal side of the proximal patellar tendon had a significantly higher accuracy compared to blind injections. The finding provides knowledge of importance for injection treatment.

  • 68.
    Abat, Ferran
    et al.
    Department of Sports Orthopaedic, ReSport Clinic Barcelona, Barcelona, Spain.
    Maffulli, Nicola
    Centre for Sports and Exercise Medicine, Queen Mary University of London Barts and The London School of Medicine, London, United Kingdom.
    Alfredson, Håkan
    Umeå University, Faculty of Medicine, Department of Community Medicine and Rehabilitation, Section of Sports Medicine.
    Lopez-Vidriero, E.
    Department of Orthopaedic, International Sports Medicine Clinic and Ibermutuamur Sevilla, Sevilla, Spain.
    Myers, C.
    Complete Physio, Tendon Performance, Sports Medicine Ultrasound Group (SMUG), London, United Kingdom.
    Gomes, S.
    Department of MSK Radiology, Clinica do Dragao Espregueira Mendes Sports Centre – FIFA Medical Centre of Excellence, Porto, Portugal.
    Chan, O.
    Department of MSK Radiology, BMI London Independent Hospital, London, United Kingdom.
    Clinical utility of diagnostic ultrasound in athletes with tendinopathy (ICL 22)2016In: Esska instructional course lecture book: Barcelona 2016 / [ed] Roland Becker; Gino M.M.J. Kerkhoffs; Pablo E. Gelber; Matteo Denti; Romain Seil, Springer Berlin/Heidelberg, 2016, p. 217-223Chapter in book (Refereed)
    Abstract [en]

    Chronic painful tendinopathy is common in elite and recreational athletes and in sedentary subjects; all may have to stop or decrease their level of physical activity [1, 2]. Midportion Achilles tendinopathy and for the younger and heavy loading population also patellar tendinopathy are problematic injuries. However, recent research on innervation patterns histopathology and pain mechanisms in Achilles and patellar tendons has led to an increased knowledge about the chronic painful tendon [3–6].

  • 69.
    Abate, Marco
    et al.
    Umeå University, Faculty of Social Sciences, Umeå School of Business and Economics (USBE), Business Administration.
    Biei, Massimo
    Umeå University, Faculty of Social Sciences, Umeå School of Business and Economics (USBE), Business Administration.
    Role of adopting response strategies to manage the Front-End phase of a project.: An exploratory study of the Italian Innovative SMEs.2016Independent thesis Advanced level (degree of Master (Two Years)), 10 credits / 15 HE creditsStudent thesis
    Abstract [en]

    The present study investigates the role of the Front-End phase within the context of Innovative Small and Medium-sized Enterprises through the project management lens, focusing on what practitioners can do to manage this phase. Taking a cue from the assumption that the Front-End phase of a project is a very critical and important stage, this study begins with a literature review on innovation and on its role among the Small and Medium-sized Enterprises, and moves to the identification of the main challengesthat an Innovative Italian Small and Medium Enterprise has to face in the Front-End phase. Particularly, the research focuses on the strategies that a project manager can implement to deal with the fuzzy nature of the Front-End phase, originated by uncertainty, equivocality and complexity. The study has an inductive approach and a cross-sectional time-horizon. A case study strategy has been employed, together with semi-structured interviews as data collection technique, involving six Italian Innovative Small and Medium-sized Enterprises identified through the framework of legal requirements provided by the European Union. Although literature poses on the same level all three elements, results show that there is a general consensus about the main role played by uncertainty. Practitioners identify several strategies to employ in order to deal with uncertainty, while the number of strategies identified to reduce equivocality and complexity is limited. Furthermore, this study identifies a correlation between the size of a company and the type of strategies employed to deal with the fuzziness. The more resource a company allocates on a project, the wider is the range of possible strategies project managers can adapt.

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  • 70.
    Abazaj, Kenneth
    Umeå University, Faculty of Social Sciences, Basic training programme for Police Officers.
    Våld i nära relationer: Polisens initiala åtgärder vid brott i nära relationer2007Independent thesis Basic level (professional degree), 5 credits / 7,5 HE creditsStudent thesis
    Abstract [sv]

    Detta arbete handlar om våld i nära relationer och avgränsar sig till mestadels kring kvinnornas situation i fråga. Mitt syfte med denna rapport är att, dels förhöja mina kunskapsnivåer inom problemområdet samt dels att utvidga och förhoppningsvis förbättra mina initiala åtgärder i mitt framtida polisiära arbete. Visserligen döms gärningsmännen idag enligt drygare dom vid brott i nära relationer än tidigare. Men de största problemen är dock fortfarande att målsägande inte vågar anmäla att de har blivit utsatta för sådana brott samt att de drar tillbaka anmälningar innan brotten hunnits utredas. Detta medför stora problem för polisens brottsbekämpning inom detta område men utgör samtidigt en oerhört viktig informationskälla för en del av den siffra över hur många sådana ouppklarade brott som årligen begås. För att sammanställa denna information i rapporten har jag tagit hjälp av litterära samlingar ur polisutbildningen termin 4, respektive fältstudier hos polismyndigheten i Skåne samt rapporter från brottsförebyggande rådet. Resultaten förblir tydliga, polisens initiala åtgärder är avgörande för hur hela utredningen bearbetas och uppklaras i slutändan. Samtidigt är samarbetet av de olika aktörerna i en kommun för brottbekämpningen och förebyggandet oerhört viktigt. Därmed säger slutsatsen i denna rapport tydligen att en skärpt disciplin inom rättsväsendet är av behov och att fullfölja dess skyldigheter i deras initiala utredningsarbeten.

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  • 71. Abbara, Aula
    et al.
    Al-Harbat, Nizar
    Karah, Nabil
    Umeå University, Faculty of Medicine, Department of Molecular Biology (Faculty of Medicine).
    Abo-Yahya, Bashar
    El-Amin, Wael
    Hatcher, James
    Gabbar, Omar
    Antimicrobial Drug Resistance among Refugees from Syria, Jordan2017In: Emerging Infectious Diseases, ISSN 1080-6040, E-ISSN 1080-6059, Vol. 23, no 5, p. 885-886Article in journal (Refereed)
  • 72.
    Abbara, Aula
    et al.
    Imperial College, London, United Kingdom.
    Almalla, Mohamed
    American University of Beirut, Beirut, Lebanon.
    AlMasri, Ibrahim
    O'Brien Institute for Public Health, Cumming School of Medicine, University of Calgary, Calgary, Canada.
    AlKabbani, Hussam
    Department of Health and Nutrition Al-Ameen for Humanitarian Support, Gaziantep, Turkey.
    Karah, Nabil
    Umeå University, Faculty of Medicine, Molecular Infection Medicine Sweden (MIMS). Umeå University, Faculty of Medicine, Umeå Centre for Microbial Research (UCMR). Umeå University, Faculty of Medicine, Department of Molecular Biology (Faculty of Medicine).
    El-Amin, Wael
    King's College Hospital London, United Arab Emirates.
    Rajan, Latha
    Tulane University School of Public Health and Tropical Medicine, Tulane University, LA, New Orleans, United States.
    Rahhal, Ibrahim
    Hand in Hand for Aid and Development, Gaziantep, Turkey.
    Alabbas, Mohammad
    Hand in Hand for Aid and Development, Gaziantep, Turkey.
    Sahloul, Zaher
    Department of Pulmonology and Critical Care, University of Illinois, IL, Chicago, United States.
    Tarakji, Ahmad
    Syrian American Medical Society, Washington DC, United States.
    Sparrow, Annie
    Department of Population Health Sciences and Policy, Icahn School of Medicine at Mount Sinai, New York, United States.
    The challenges of tuberculosis control in protracted conflict: The case of Syria2020In: International Journal of Infectious Diseases, ISSN 1201-9712, E-ISSN 1878-3511, International Journal of Infectious Diseases, ISSN 1201-9712, Vol. 90, p. 53-59Article, review/survey (Refereed)
    Abstract [en]

    Objectives: Syria's protracted conflict has resulted in ideal conditions for the transmission of tuberculosis (TB) and the cultivation of drug-resistant strains. This paper compares TB control in Syria before and after the conflict using available data, examines the barriers posed by protracted conflict and those specific to Syria, and discusses what measures can be taken to address the control of TB in Syria.

    Results: Forced mass displacement and systematic violations of humanitarian law have resulted in overcrowding and the destruction of key infrastructure, leading to an increased risk of both drug-sensitive and resistant TB, while restricting the ability to diagnose, trace contacts, treat, and follow-up. Pre-conflict, TB in Syria was officially reported at 22 per 100 000 population; the official figure for 2017 of 19 per 100 000 is likely a vast underestimate given the challenges and barriers to case detection. Limited diagnostics also affect the diagnosis of multidrug- and rifampicin-resistant TB, reported as comprising 8.8% of new diagnoses in 2017.

    Conclusions: The control of TB in Syria requires a multipronged, tailored, and pragmatic approach to improve timely diagnosis, increase detection, stop transmission, and mitigate the risk of drug resistance. Solutions must also consider vulnerable populations such as imprisoned and besieged communities where the risk of drug resistance is particularly high, and must recognize the limitations of national programming. Strengthening capacity to control TB in Syria with particular attention to these factors will positively impact other parallel conditions; this is key as attention turns to post-conflict reconstruction.

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  • 73.
    Abbara, Aula
    et al.
    Department of Infection, Imperial College, St Marys Hospital, London, United Kingdom; Syria Public Health Network, London, United Kingdom.
    Almhawish, Naser
    Assistance Coordination Unit, Gaziantep, Turkey.
    Aladhan, Ibrahim
    Environmental Protection Agency of Syria, Gaziantep, Turkey.
    Alobaid, Redwan
    Assistance Coordination Unit, Gaziantep, Turkey.
    Karah, Nabil
    Umeå University, Faculty of Medicine, Department of Molecular Biology (Faculty of Medicine).
    Weaponisation of water2022In: The Lancet, ISSN 0140-6736, E-ISSN 1474-547X, Vol. 400, no 10367, p. 1925-1925Article in journal (Refereed)
  • 74. Abbara, Aula
    et al.
    Rawson, Timothy M.
    Karah, Nabil
    Umeå University, Faculty of Medicine, Department of Molecular Biology (Faculty of Medicine). Umeå University, Faculty of Medicine, Molecular Infection Medicine Sweden (MIMS). Umeå University, Faculty of Medicine, Umeå Centre for Microbial Research (UCMR).
    El-Amin, Wael
    Hatcher, James
    Tajaldin, Bachir
    Dar, Osman
    Dewachi, Omar
    Abu Sitta, Ghassan
    Uhlin, Bernt Eric
    Umeå University, Faculty of Medicine, Umeå Centre for Microbial Research (UCMR). Umeå University, Faculty of Medicine, Molecular Infection Medicine Sweden (MIMS). Umeå University, Faculty of Medicine, Department of Molecular Biology (Faculty of Medicine).
    Sparrow, Annie
    A summary and appraisal of existing evidence of antimicrobial resistance in the Syrian conflict2018In: International Journal of Infectious Diseases, ISSN 1201-9712, E-ISSN 1878-3511, Vol. 75, p. 26-33Article, review/survey (Refereed)
    Abstract [en]

    Antimicrobial resistance (AMR) in populations experiencing war has yet to be addressed, despite the abundance of contemporary conflicts and the protracted nature of twenty-first century wars, in combination with growing global concern over conflict-associated bacterial pathogens. The example of the Syrian conflict is used to explore the feasibility of using existing global policies on AMR in conditions of extreme conflict. The available literature on AMR and prescribing behaviour in Syria before and since the onset of the conflict in March 2011 was identified. Overall, there is a paucity of rigorous data before and since the onset of conflict in Syria to contextualize the burden of AMR. However, post onset of the conflict, an increasing number of studies conducted in neighbouring countries and Europe have reported AMR in Syrian refugees. High rates of multidrug resistance, particularly Gram-negative organisms, have been noted amongst Syrian refugees when compared with local populations. Conflict impedes many of the safeguards against AMR, creates new drivers, and exacerbates existing ones. Given the apparently high rates of AMR in Syria, in neighbouring countries hosting refugees, and in European countries providing asylum, this requires the World Health Organization and other global health institutions to address the causes, costs, and future considerations of conflict-related AMR as an issue of global governance. (c) 2018 The Authors. Published by Elsevier Ltd on behalf of International Society for Infectious Diseases.

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  • 75. Abbara, Aula
    et al.
    Rawson, Timothy M.
    Karah, Nabil
    Umeå University, Faculty of Medicine, Department of Molecular Biology (Faculty of Medicine). Umeå University, Faculty of Medicine, Molecular Infection Medicine Sweden (MIMS). Umeå University, Faculty of Medicine, Umeå Centre for Microbial Research (UCMR).
    El-Amin, Wael
    Hatcher, James
    Tajaldin, Bachir
    Dar, Osman
    Dewachi, Omar
    Abu Sitta, Ghassan
    Uhlin, Bernt Eric
    Umeå University, Faculty of Medicine, Umeå Centre for Microbial Research (UCMR). Umeå University, Faculty of Medicine, Molecular Infection Medicine Sweden (MIMS). Umeå University, Faculty of Medicine, Department of Molecular Biology (Faculty of Medicine).
    Sparrow, Annie
    Antimicrobial resistance in the context of the Syrian conflict: Drivers before and after the onset of conflict and key recommendations2018In: International Journal of Infectious Diseases, ISSN 1201-9712, E-ISSN 1878-3511, Vol. 73, p. 1-6Article, review/survey (Refereed)
    Abstract [en]

    Current evidence describing antimicrobial resistance (AMR) in the context of the Syrian conflict is of poor quality and sparse in nature. This paper explores and reports the major drivers of AMR that were present in Syria pre-conflict and those that have emerged since its onset in March 2011. Drivers that existed before the conflict included a lack of enforcement of existing legislation to regulate over-the-counter antibiotics and notification of communicable diseases. This contributed to a number of drivers of AMR after the onset of conflict, and these were also compounded by the exodus of trained staff, the increase in overcrowding and unsanitary conditions, the increase in injuries, and economic sanctions limiting the availability of required laboratory medical materials and equipment. Addressing AMR in this context requires pragmatic, multifaceted action at the local, regional, and international levels to detect and manage potentially high rates of multidrug-resistant infections. Priorities are (1) the development of a competent surveillance system for hospital-acquired infections, (2) antimicrobial stewardship, and (3) the creation of cost-effective and implementable infection control policies. However, it is only by addressing the conflict and immediate cessation of the targeting of health facilities that the rehabilitation of the health system, which is key to addressing AMR in this context, can progress. 

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  • 76.
    Abbara, Aula
    et al.
    Imperial College, London, United Kingdom; Syria Public Health Network, United Kingdom.
    Zakieh, Omar
    Imperial College, London, United Kingdom.
    Rayes, Diana
    Syria Public Health Network, United Kingdom; Johns Hopkins, United States.
    Collin, Simon M.
    Public Health England, United Kingdom.
    Almhawish, Naser
    Assistance Coordination Unit, Turkey.
    Sullivan, Richard
    King's College, London, United Kingdom.
    Aladhan, Ibrahim
    Assistance Coordination Unit, Turkey.
    Tarnas, Maia
    Community Research Initiative, MA, Charlestown, United States.
    Whalen-Browne, Molly
    University of Alberta, Edmonton, Canada.
    Omar, Maryam
    St Bartholomew's Hospital, London, United Kingdom.
    Tarakji, Ahmad
    Syrian American Medical Society, United States.
    Karah, Nabil
    Umeå University, Faculty of Medicine, Department of Molecular Biology (Faculty of Medicine).
    Weaponizing water as an instrument of war in Syria: Impact on diarrhoeal disease in Idlib and Aleppo governorates, 2011–20192021In: International Journal of Infectious Diseases, ISSN 1201-9712, E-ISSN 1878-3511, Vol. 108, p. 202-208Article in journal (Refereed)
    Abstract [en]

    Objectives: Investigate the weaponization of water during the Syrian conflict and the correlation of attacks on water, sanitation, and hygiene (WASH) infrastructure in Idlib and Aleppo governorates with trends in waterborne diseases reported by Early Warning and Response surveillance systems.

    Methods: We reviewed literature and databases to obtain information on attacks on WASH in Aleppo and Idlib governorates between 2011 and 2019. We plotted weekly trends in waterborne diseases from two surveillance systems operational in Aleppo and Idlib governorates between 2015 and early 2020.

    Results: The literature review noted several attacks on water and related infrastructure in both governorates, suggesting that WASH infrastructure was weaponized by state and non-state actors. Most interference with WASH in the Aleppo governorate occurred before 2019 and in the Idlib governorate in the summer of 2020. Other acute diarrhea represented >90% of cases of diarrhea; children under 5 years contributed 50% of cases. There was substantial evidence (p < 0.001) of an overall upward trend in cases of diarrheal disease.

    Conclusions: Though no direct correlation can be drawn between the weaponization of WASH and the burden of waterborne infections due to multiple confounders, this research introduces important concepts on attacks on WASH and their potential impacts on waterborne diseases.

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  • 77.
    Abbas, Ali
    Umeå University, Faculty of Social Sciences, Umeå School of Business and Economics (USBE), Economics.
    Determinants of women's labour supply in Bangladesh and Pakistan2013Independent thesis Advanced level (degree of Master (Two Years)), 10 credits / 15 HE creditsStudent thesis
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    Determinants of women's labour supply in Bangladesh and Pakistan
  • 78.
    Abbas, Ali
    Umeå University, Faculty of Social Sciences, Umeå School of Business and Economics (USBE), Economics.
    The European Union’s Technological and Economic Development: A Study on Production of Renewable Energy2018Independent thesis Advanced level (degree of Master (Two Years)), 10 credits / 15 HE creditsStudent thesis
    Abstract [en]

    This thesis answer the two main questions, firstly, the role of technological development in the production of RE with special reference to investment subsidy in supporting schemes and research and development (R&D). Investment subsidies in supporting schemes and R&D are widely used to promote RE technology and considered economical, efficient instruments than regulation approach. Secondly, the study investigates the relationship between the production of RE and the economic development. Panel data for twelve European Union (EU) countries are analysed for the period 1990 to 2013. The study uses a Cobb Douglas production function to estimate the EU's rational behaviour of investment subsidy between supporting schemes and R&D. For the estimation techniques, the study uses the unit root test, cointegration test, and dynamic pooling average group (PMG) model. The selection of the PMG model is based on the results of diagnostic tests, i.e. cross-sectional dependence, heteroskedasticity, serial correlation, and Hausman. Furthermore, the cointegration test confirms that in the long-run all the variables move together to achieve equilibrium. The PMG model confirms the effect of the independent variables on the dependent variable. Thus, it is concluded that the investment subsidies in supporting schemes have a positive and significant effect on the production of renewable energy in the long-run. However, the investment subsidy in research and development also has a positive but insignificant effect on the production of renewable energy in the long-run. Based on the long-run result, thus the study suggests that it is more rational to invest subsidy in supporting schemes than in R&D. In order to find the relationship between the production of RE and economic development, the result of the study confirms that economic development has a positive and significant impact on the production of renewable energy both in the short-and long-run. In addition, the test of the causality confirms the bidirectional relationship between production of RE and economic development. The bidirectional relationship states that both energy and economic growth are associated and complement each other.

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    The European Union’s Technological and Economic Development: A Study on Production of Renewable Energy
  • 79. Abbas, S
    et al.
    Linseisen, J
    Rohrmann, S
    Beulens, JWJ
    Buijsse, B
    Amiano, P
    Ardanaz, E
    Balkau, B
    Boeing, H
    Clavel-Chapelon, F
    Fagherazzi, G
    Franks, Paul W
    Umeå University, Faculty of Medicine, Department of Public Health and Clinical Medicine, Medicine.
    Gavrila, D
    Grioni, S
    Kaaks, R
    Key, TJ
    Khaw, KT
    Kuehn, T
    Mattiello, A
    Molina-Montes, E
    Nilsson, PM
    Overvad, K
    Quiros, JR
    Rolandsson, Olov
    Umeå University, Faculty of Medicine, Department of Public Health and Clinical Medicine, Family Medicine.
    Sacerdote, C
    Saieva, C
    Slimani, N
    Sluijs, I
    Spijkerman, AMW
    Tjonneland, A
    Tumino, R
    van der A, DL
    Zamora-Ros, R
    Sharp, SJ
    Langenberg, C
    Forouhi, NG
    Riboli, E
    Wareham, NJ
    Dietary vitamin D intake and risk of type 2 diabetes in the European Prospective Investigation into Cancer and Nutrition: the EPIC-InterAct study2014In: European Journal of Clinical Nutrition, ISSN 0954-3007, E-ISSN 1476-5640, Vol. 68, no 2, p. 196-202Article in journal (Refereed)
    Abstract [en]

    BACKGROUND/OBJECTIVES: Prospective cohort studies have indicated that serum vitamin D levels are inversely related to risk of type 2 diabetes. However, such studies cannot determine the source of vitamin D. Therefore, we examined the association of dietary vitamin D intake with incident type 2 diabetes within the European Prospective Investigation into Cancer and Nutrition (EPIC)-InterAct study in a heterogeneous European population including eight countries with large geographical variation.

    SUBJECTS/METHODS: Using a case-cohort design, 11 245 incident cases of type 2 diabetes and a representative subcohort (N = 15 798) were included in the analyses. Hazard ratios (HR) and 95% confidence intervals (CIs) for type 2 diabetes were calculated using a Prentice-weighted Cox regression adjusted for potential confounders. Twenty-four-hour diet-recall data from a subsample (N = 2347) were used to calibrate habitual intake data derived from dietary questionnaires.

    RESULTS: Median follow-up time was 10.8 years. Dietary vitamin D intake was not significantly associated with the risk of type 2 diabetes. HR and 95% CIs for the highest compared to the lowest quintile of uncalibrated vitamin D intake was 1.09 (0.97-1.22) (P-trend = 0.17). No associations were observed in a sex-specific analysis. The overall pooled effect (HR (95% CI)) using the continuous calibrated variable was 1.00 (0.97-1.03) per increase of 1 mg/day dietary vitamin D.

    CONCLUSIONS: This observational study does not support an association between higher dietary vitamin D intake and type 2 diabetes incidence. This result has to be interpreted in light of the limited contribution of dietary vitamin D on the overall vitamin D status of a person.

  • 80. Abbas, Sascha
    et al.
    Linseisen, Jakob
    Rohrmann, Sabine
    Chang-Claude, Jenny
    Peeters, Petra H
    Engel, Pierre
    Brustad, Magritt
    Lund, Eiliv
    Skeie, Guri
    Olsen, Anja
    Tjønneland, Anne
    Overvad, Kim
    Boutron-Ruault, Marie-Christine
    Clavel-Chapelon, Francoise
    Fagherazzi, Guy
    Kaaks, Rudolf
    Boeing, Heiner
    Buijsse, Brian
    Adarakis, George
    Ouranos, Vassilis
    Trichopoulou, Antonia
    Masala, Giovanna
    Krogh, Vittorio
    Mattiello, Amalia
    Tumino, Rosario
    Sacerdote, Carlotta
    Buckland, Genevieve
    Suárez, Marcial Vicente Argüelles
    Sánchez, Maria-José
    Chirlaque, Maria-Dolores
    Barricarte, Aurelio
    Amiano, Pilar
    Manjer, Jonas
    Wirfält, Elisabet
    Lenner, Per
    Umeå University, Faculty of Medicine, Department of Radiation Sciences, Oncology.
    Sund, Malin
    Umeå University, Faculty of Medicine, Department of Surgical and Perioperative Sciences, Surgery.
    Bueno-de-Mesquita, H B
    van Duijnhoven, Fränzel J B
    Khaw, Kay-Tee
    Wareham, Nick
    Key, Timothy J
    Fedirko, Veronika
    Romieu, Isabelle
    Gallo, Valentina
    Norat, Teresa
    Wark, Petra A
    Riboli, Elio
    Dietary intake of vitamin D and calcium and breast cancer risk in the European prospective investigation into cancer and nutrition2013In: Nutrition and Cancer, ISSN 0163-5581, E-ISSN 1532-7914, Vol. 65, no 2, p. 178-187Article in journal (Refereed)
    Abstract [en]

    Studies assessing the effects of vitamin D or calcium intake on breast cancer risk have been inconclusive. Furthermore, few studies have evaluated them jointly. This study is the largest so far examining the association of dietary vitamin D and calcium intake with breast cancer risk in the European Prospective Investigation into Cancer and Nutrition. During a mean follow-up of 8.8 yr, 7760 incident invasive breast cancer cases were identified among 319,985 women. Multivariable Cox proportional hazards regression was used to estimate hazard ratios (HR) and 95% confidence intervals (CI) for pre- and postmenopausal breast cancer risk. Comparing the highest with the lowest quintile of vitamin D intake, HR and 95% CI were 1.07 (0.87-1.32) and 1.02 (0.90-1.16) for pre- and postmenopausal women, respectively. The corresponding HR and 95% CIs for calcium intake were 0.98 (0.80-1.19) and 0.90 (0.79-1.02), respectively. For calcium intake in postmenopausal women, the test for trend was borderline statistically significant (P(trend) = 0.05). There was no significant interaction between vitamin D and calcium intake and cancer risk (P(interaction) = 0.57 and 0.22 in pre- and postmenopausal women, respectively). In this large prospective cohort, we found no evidence for an association between dietary vitamin D or calcium intake and breast cancer risk.

  • 81.
    Abbasi, Ahtisham Fazeel
    et al.
    German Research Center for Artificial Intelligence (DFKI), Kaiserslautern, Germany; University of Kaiserslautern-Landau, Kaiserslautern (RPTU), Germany.
    Asim, Muhammad Nabeel
    German Research Center for Artificial Intelligence (DFKI), Kaiserslautern, Germany.
    Trygg, Johan
    Umeå University, Faculty of Science and Technology, Department of Chemistry. Sartorius Corporate Research, Sartorius Stedim Data Analytics, Umeå, Sweden.
    Dengel, Andreas
    German Research Center for Artificial Intelligence (DFKI), Kaiserslautern, Germany; University of Kaiserslautern-Landau, Kaiserslautern (RPTU), Germany.
    Ahmed, Sheraz
    German Research Center for Artificial Intelligence (DFKI), Kaiserslautern, Germany.
    Deep learning architectures for the prediction of YY1-mediated chromatin loops2023In: Bioinformatics research and applications: 19th international symposium, ISBRA 2023, Wrocław, Poland, October 9–12, 2023, proceedings / [ed] Xuan Guo; Serghei Mangul; Murray Patterson; Alexander Zelikovsky, Springer, 2023, p. 72-84Conference paper (Refereed)
    Abstract [en]

    YY1-mediated chromatin loops play substantial roles in basic biological processes like gene regulation, cell differentiation, and DNA replication. YY1-mediated chromatin loop prediction is important to understand diverse types of biological processes which may lead to the development of new therapeutics for neurological disorders and cancers. Existing deep learning predictors are capable to predict YY1-mediated chromatin loops in two different cell lines however, they showed limited performance for the prediction of YY1-mediated loops in the same cell lines and suffer significant performance deterioration in cross cell line setting. To provide computational predictors capable of performing large-scale analyses of YY1-mediated loop prediction across multiple cell lines, this paper presents two novel deep learning predictors. The two proposed predictors make use of Word2vec, one hot encoding for sequence representation and long short-term memory, and a convolution neural network along with a gradient flow strategy similar to DenseNet architectures. Both of the predictors are evaluated on two different benchmark datasets of two cell lines HCT116 and K562. Overall the proposed predictors outperform existing DEEPYY1 predictor with an average maximum margin of 4.65%, 7.45% in terms of AUROC, and accuracy, across both of the datases over the independent test sets and 5.1%, 3.2% over 5-fold validation. In terms of cross-cell evaluation, the proposed predictors boast maximum performance enhancements of up to 9.5% and 27.1% in terms of AUROC over HCT116 and K562 datasets.

  • 82. Abbasi, Arshad Mehmood
    et al.
    Khan, Mir Ajab
    Khan, Nadeem
    Umeå University, Faculty of Science and Technology, Department of Plant Physiology. Umeå University, Faculty of Science and Technology, Umeå Plant Science Centre (UPSC).
    Shah, Munir H
    Ethnobotanical survey of medicinally important wild edible fruits species used by tribal communities of Lesser Himalayas-Pakistan2013In: Journal of Ethnopharmacology, ISSN 0378-8741, E-ISSN 1872-7573, Vol. 148, no 2, p. 528-536Article in journal (Refereed)
    Abstract [en]

    Ethnopharmacological relevance: Present survey was conducted to explore ethnomedicinal uses and cultural importance of wild edible fruits species by the inhabitants of Lesser Himalayas-Pakistan. Materials and methods: Information was obtained through informed consent semi-structured interviews, questionnaires, market survey, focus group conversation, unceremonious dialogue and village walks with key informants. Cultural significance of each species was calculated based on use report by participants at each study site. Results: A total of 35 wild edible fruits belonging to 21 genera and 17 families were used for the treatment of various ailments and consumed. Rosaceae was found dominating family with (8 spp.), followed by Moraceae (6 spp.), Rhamnaceae (5 spp.), Palmae and Vitaceae (2 spp. each) and remaining families were represented by one species each. Fruits (48%) were found highly utilized plant parts, followed by leaves (34%), bark, flowers and seeds (4% each), branches, latex and roots (2% each). Water was used as a medium for preparation while milk, ghee, oil, egg and butter are used for application. Modes of preparation were fall into seven categories like fresh parts eaten raw (38%), powder (24%), decoction (20%), extract (12 %), paste (4%), juice and latex (2% each). Based on cultural important index (CI) Morus nigra was found most significant species within top ten fruit plants followed by Morus alba, Olea ferruginea, Berberis lycium, Pyrus pashia, Ficus carica, Ficus palmata, Ziziphus mauritiana, Diospyros lotus and Ziziphus nummularia. Conclusions: Traditional uses of wild edible plant depend mainly on socio-economic factors rather than climatic conditions or wealth of flora. Use reports and citation demonstrated that there is a common cultural heritage regarding the gathered food plants. Further investigation is required for Antioxidant study, essential and toxic components, pharmacological applications; dietary requirements and biotechnological techniques to improve yields.

    (C) 2013 Elsevier Ireland Ltd. All rights reserved.

  • 83.
    Abbasi, Farid
    Umeå University, Faculty of Science and Technology, Umeå School of Architecture.
    The High Garden: An architectural exploration on how to integrate vertical farming and modular architecture inside city centres2020Independent thesis Advanced level (degree of Master (Two Years)), 20 credits / 30 HE creditsStudent thesis
    Abstract [en]

    The state of the world is changing. By 2050, The earth’s population will increase by 3 billion and building sector is asked to construct 3 billion new housing units inside urban centres. Since one of the fundamental needs is food, agriculture sector also needs to adjust itself to this growing number of people. Nevertheless, in 2019, Agriculture used 50 per cent of all earth’s habitable land and experts estimate that we need 109 hectares more land to cultivate however this amount of habitable land is approximately the land which is represented by the country of Brazil and 20 per cent more. Moreover, the Food and Agriculture Organization of the United Nations states that water use grew twice as much as population increase and agriculture already is using approximately 70 per cent of the global freshwater. At this point, experts like Professor Dickinson Despommier suggests that the only way humanity can tackle its future food safety issues is to find ways to introduce vertical farming inside Urban centres. The High Garden project is resulted by the world state today and is trying to find an architectural solution to the mentioned issues. It starts firstly by studying the issues more thoroughly and then tries to form a framework which includes and transcends them. It studies how the construction sector is acting now and how it can reorient itself to the situation whilst limiting its negative environmental impact. Then the thesis tries to understand the basics of vertical farming methods compared to the conventional geoponics farming as it is practised today and how it can integrate the better cultivation solution inside city centres. The last step of the theoretical studies of the project is to look at the history of integrated farming and EcoArchitecture. After understanding the theories of the issue, then the thesis starts to form itself as an architectural intervention using the architectural tools and methods and combining the studied disciplines. The result of the thesis is a modular configuration which can accommodate various activities such as aeroponic farming, local markets, zen areas, and drone subscription deliveries etc. Because of the modular construction of the project, it can adapt and adjust itself to different situations and it uses an algorithmic tool to analyse and study existing cities to find proper intervention points. Then it is attached to the existing buildings as a sustainable green extension solving some issues and revitalizing the dead city edges. Keywords: State of the World, rapid urbanization, population growth, geoponic agriculture, Co2 emission, greenhouse gas emission, aeroponic farming, modular architecture, sustainable architecture, EcoArchitecture

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    The High Garden: An architectural exploration on how to integrate vertical farming and modular architecture inside city centres
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    The High Garden Design Portfolio
  • 84.
    Abbasi, Jasim Aftab
    Umeå University, Faculty of Science and Technology, Department of Applied Physics and Electronics.
    Test of Rapid Control System Development using TargetLink2012Independent thesis Advanced level (degree of Master (Two Years)), 20 credits / 30 HE creditsStudent thesis
    Abstract [en]

    The aim of this thesis is to employ and evaluate an evaluation board with the standard microprocessor freescale MPC5554EVB board for implementation of control algorithms which are created in Matlab/Simulink instead of using dSPACE prototyping hardware. The Simulink real-time model shall be compiled to the MPC5554EVB board. TargetLink is a powerful software tool which allows an automatic generation of efficient C code from Simulink and facilitates model-based control design. The goal of this thesis is to learn how to use TargetLink in a control design workflow from model to real code and what are the limitations of a microprocessor platform and to evaluate the capabilities of TargetLink to generate a working code for a generic microprocessor.

  • 85. Abbasian, Saeid
    et al.
    Müller, Dieter K.
    Umeå University, Faculty of Social Sciences, Department of Geography.
    Displaced diaspora second-home tourism: an explorative study of Swedish-Iranians and their second-home purchases in Turkey2019In: Tourism, ISSN 1332-7461, E-ISSN 1849-1545, Vol. 67, no 3, p. 239-252Article in journal (Refereed)
    Abstract [en]

    This explorative study aims to gain more insight into Swedish-Iranians' purchase of second homes in Turkey. The study is based on 22 questionnaires (19 of them from owners and buyers), field observation, and participant observation. Motives behind owners' and buyers' purchases are: other Swedish-Iranian friends/relatives bought there; cultural proximity; absence of visa restriction for Iranian citizens; geographical proximity to Iran and relatives living in Iran; economic factors, including the low prices and costs and investment for retirement; and the climate. The respondents are well-integrated into Swedish society and have access to different types of resources which facilitate the purchase, but they also show the potential to partially become integrated socioculturally into their Turkish communities. A meaningful proportion of them are seriously planning to live permanently in Turkey after retirement, but the majority stay there for longer periods or semi-permanently. Despite some limitations, this study makes an important contribution to the area of diaspora second-home tourism and to the field of diaspora studies.

  • 86.
    Abbevik, Julia
    Umeå University, Faculty of Science and Technology, Umeå School of Architecture.
    A city for youths: An urban strategy to encourage and enhance existing activities and activate social space to strengthen youths leisure time in Lycksele2020Independent thesis Advanced level (degree of Master (Two Years)), 20 credits / 30 HE creditsStudent thesis
    Abstract [en]

    On a national scale, statistics relating to moving patterns shows that youths and young adults are the ones who tend to move the most. The case in Västerbotten is similar as in the rest of Sweden and many municipalities are experiencing a population decline. This thesis aims to look into the motives behind moving from the perspective of youths and young adults and through that propose a strategy to strengthen the place attachment youths and young adults feel to their home municipality. The research is centered around Lycksele in Västerbotten.

    The research questions that the thesis aims to seek answers for are; What could an architectural strategy that aims to support youths in their leisure time and also strengthen their connection to the area look like? and What programmatic aspects are important to consider in such a strategy?

    The thesis investigates spatial needs from the perspective of youths and young adults which have been investigated through literature studies and action based research focused on interviews and a workshop. Four themes were common in both interviews and the workshop, these were; closeness to nature, possibility of work, valuable leisure time and a sense of home. To understand how an urban strategy can respond to the themes, strategies applied in other municipalities have been analysed. A finding was that in order for strategies to attract more inhabitants, they need to have a holistic approach and offer a complete lifestyle. Creativity is a theme which came up during interviews and literature studies as a possible platform around which an area can become considered as more attractive.

    The proposal is an urban strategy which aims to respond to the common themes from interviews and the workshop by enhancing and encouraging activities taking place and activating social space. This proposal suggests a strategy which aims to strengthen the notion of sense of place to enhance place attachment and through that possibly invite more young adults to move back in the future.

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    Thesis text
  • 87.
    Abbevik, Julia
    Umeå University, Faculty of Science and Technology, Umeå School of Architecture.
    Open Music2017Independent thesis Basic level (degree of Bachelor of Fine Arts), 10 credits / 15 HE creditsStudent thesis
  • 88.
    Abbood, Maab Mohammed Abbood
    Umeå University, Faculty of Medicine, Department of Integrative Medical Biology (IMB).
    Bildning av ett elektroaktivt lipiddubbelskikt för studie av membranfördelningsbeteendet hos joniska läkemedel_ En laborativ studie2023Independent thesis Advanced level (professional degree), 20 credits / 30 HE creditsStudent thesis
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  • 89. Abbott, Benjamin W.
    et al.
    Jones, Jeremy B.
    Schuur, Edward A. G.
    Chapin, F. Stuart, III
    Bowden, William B.
    Bret-Harte, M. Syndonia
    Epstein, Howard E.
    Flannigan, Michael D.
    Harms, Tamara K.
    Hollingsworth, Teresa N.
    Mack, Michelle C.
    McGuire, A. David
    Natali, Susan M.
    Rocha, Adrian V.
    Tank, Suzanne E.
    Turetsky, Merritt R.
    Vonk, Jorien E.
    Wickland, Kimberly P.
    Aiken, George R.
    Alexander, Heather D.
    Amon, Rainer M. W.
    Benscoter, Brian W.
    Bergeron, Yves
    Bishop, Kevin
    Blarquez, Olivier
    Bond-Lamberty, Ben
    Breen, Amy L.
    Buffam, Ishi
    Cai, Yihua
    Carcaillet, Christopher
    Carey, Sean K.
    Chen, Jing M.
    Chen, Han Y. H.
    Christensen, Torben R.
    Cooper, Lee W.
    Cornelissen, J. Hans C.
    de Groot, William J.
    DeLuca, Thomas H.
    Dorrepaal, Ellen
    Umeå University, Faculty of Science and Technology, Department of Ecology and Environmental Sciences.
    Fetcher, Ned
    Finlay, Jacques C.
    Forbes, Bruce C.
    French, Nancy H. F.
    Gauthier, Sylvie
    Girardin, Martin P.
    Goetz, Scott J.
    Goldammer, Johann G.
    Gough, Laura
    Grogan, Paul
    Guo, Laodong
    Higuera, Philip E.
    Hinzman, Larry
    Hu, Feng Sheng
    Hugelius, Gustaf
    Jafarov, Elchin E.
    Jandt, Randi
    Johnstone, Jill F.
    Karlsson, Jan
    Umeå University, Faculty of Science and Technology, Department of Ecology and Environmental Sciences.
    Kasischke, Eric S.
    Kattner, Gerhard
    Kelly, Ryan
    Keuper, Frida
    Umeå University, Faculty of Science and Technology, Department of Ecology and Environmental Sciences.
    Kling, George W.
    Kortelainen, Pirkko
    Kouki, Jari
    Kuhry, Peter
    Laudon, Hjalmar
    Laurion, Isabelle
    Macdonald, Robie W.
    Mann, Paul J.
    Martikainen, Pertti J.
    McClelland, James W.
    Molau, Ulf
    Oberbauer, Steven F.
    Olefeldt, David
    Pare, David
    Parisien, Marc-Andre
    Payette, Serge
    Peng, Changhui
    Pokrovsky, Oleg S.
    Rastetter, Edward B.
    Raymond, Peter A.
    Raynolds, Martha K.
    Rein, Guillermo
    Reynolds, James F.
    Robards, Martin
    Rogers, Brendan M.
    Schaedel, Christina
    Schaefer, Kevin
    Schmidt, Inger K.
    Shvidenko, Anatoly
    Sky, Jasper
    Spencer, Robert G. M.
    Starr, Gregory
    Striegl, Robert G.
    Teisserenc, Roman
    Tranvik, Lars J.
    Virtanen, Tarmo
    Welker, Jeffrey M.
    Zimov, Sergei
    Biomass offsets little or none of permafrost carbon release from soils, streams, and wildfire: an expert assessment2016In: Environmental Research Letters, E-ISSN 1748-9326, Vol. 11, no 3, article id 034014Article in journal (Refereed)
    Abstract [en]

    As the permafrost region warms, its large organic carbon pool will be increasingly vulnerable to decomposition, combustion, and hydrologic export. Models predict that some portion of this release will be offset by increased production of Arctic and boreal biomass; however, the lack of robust estimates of net carbon balance increases the risk of further overshooting international emissions targets. Precise empirical or model-based assessments of the critical factors driving carbon balance are unlikely in the near future, so to address this gap, we present estimates from 98 permafrost-region experts of the response of biomass, wildfire, and hydrologic carbon flux to climate change. Results suggest that contrary to model projections, total permafrost-region biomass could decrease due to water stress and disturbance, factors that are not adequately incorporated in current models. Assessments indicate that end-of-the-century organic carbon release from Arctic rivers and collapsing coastlines could increase by 75% while carbon loss via burning could increase four-fold. Experts identified water balance, shifts in vegetation community, and permafrost degradation as the key sources of uncertainty in predicting future system response. In combination with previous findings, results suggest the permafrost region will become a carbon source to the atmosphere by 2100 regardless of warming scenario but that 65%-85% of permafrost carbon release can still be avoided if human emissions are actively reduced.

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  • 90.
    Abd Alrahman, Chadi
    et al.
    Umeå University, Faculty of Science and Technology, Department of Physics.
    Khodabakhsh, Amir
    Umeå University, Faculty of Science and Technology, Department of Physics.
    Schmidt, Florian M.
    Umeå University, Faculty of Science and Technology, Department of Applied Physics and Electronics.
    Qu, Zhechao
    Umeå University, Faculty of Science and Technology, Department of Applied Physics and Electronics.
    Foltynowicz, Aleksandra
    Umeå University, Faculty of Science and Technology, Department of Physics.
    Cavity-enhanced optical frequency comb spectroscopy of high-temperature H2O in a flame2014In: Optics Express, E-ISSN 1094-4087, Vol. 22, no 11, p. 13889-13895Article in journal (Refereed)
    Abstract [en]

    We demonstrate near-infrared cavity-enhanced optical frequency comb spectroscopy of water in a premixed methane/air flat flame. The detection system is based on an Er:fiber femtosecond laser, a high finesse optical cavity containing the flame, and a fast-scanning Fourier transform spectrometer (FTS). High absorption sensitivity is obtained by the combination of a high-bandwidth two-point comb-cavity lock and auto-balanced detection in the FTS. The system allows recording high-temperature water absorption spectra with a resolution of 1 GHz and a bandwidth of 50 nm in an acquisition time of 0.4 s, with absorption sensitivity of 4.2 x 10 (9) cm(-1) Hz(-1/2) per spectral element.

  • 91.
    Abd Mohammed, Mena
    Umeå University, Faculty of Medicine, Department of Odontology.
    Dental treatment under general anesthesia for children in the county of Västerbotten2012Independent thesis Advanced level (degree of Master (Two Years)), 20 credits / 30 HE creditsStudent thesis
  • 92.
    Abdali Cabrera, Nadia
    et al.
    Umeå University, Faculty of Social Sciences, Department of Social Work.
    Eriksson, Linn
    Umeå University, Faculty of Social Sciences, Department of Social Work.
    Socionomstudenters välbefinnande: En studie om studenternas psykosociala välbefinnande vid Umeå Universitet2014Independent thesis Basic level (degree of Bachelor), 10 credits / 15 HE creditsStudent thesis
    Abstract [sv]

    Sammanfattning

    Studien syftade till att kartlägga och beskriva hur det psykosociala välbefinnandet såg ut bland socionomstudenterna vid Umeå universitet.  Tidigare forskning visar på att nedsatt välbefinnande är vanligt bland studenter.  Genom att undersöka studenternas psykosociala studiesituation i relation till deras subjektiva och objektiva välbefinnande kartlades en bild av hur det ser ut på socionomprogrammet. Studien omfattar alla campusstuderande terminer vid Umeå universitet. Krav-, kontroll- och stödmodellen har använts för att beskriva studenternas psykosociala arbetsmiljö och General Health Questionnaire 12 (GHQ-12) användes för att mäta studenternas välbefinnande. En enkät skickades ut till samtliga studenter, vilken innehöll kvantitativa och kvalitativa inslag. Resultaten visar att 47,2% av studenterna har ett nedsatt välbefinnande samt att 64,2 % upplevde lätta eller svåra upplevelser av ångest, oro eller ängslan. Majoriteten av studenterna hade besvär med sömnen och visade på trötthetstecken som huvudvärk samt upplevde stress i relation till sina studier. Ju högre stress studenten upplever desto sämre välbefinnande. Studenterna visade på högt eget inflytande över sina studier (94,6%) samt att de kan hantera de krav som ställs på dem (97,3%).

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    Studenters välbefinnande
  • 93.
    Abdalla, Lahood
    et al.
    Umeå University, Faculty of Medicine, Wallenberg Centre for Molecular Medicine at Umeå University (WCMM). Umeå University, Faculty of Medicine, Department of Odontology, School of Dentistry.
    Soltani, Bagir
    Umeå University, Faculty of Medicine, Department of Odontology, School of Dentistry.
    The effect of calcium silicate-based cements on viability and differentiation of human stem cells from the dental apical papilla.: Future aspects in endodontic regeneration.2023Independent thesis Advanced level (degree of Master (Two Years)), 20 credits / 30 HE creditsStudent thesis
    Abstract [en]

    Introduction:

    Pulp necrosis in immature permanent teeth stops root development and may lead to higher risk of cervical fractures and a challenging treatment. Regenerative endodontic treatment (RET) aims to continue tooth development and implies the use of calcium silicate-based cements, such as Mineral trioxide aggregate (MTA) and Biodentine to seal the root canal. However, its effect on stem cells has been poorly explored. 

    Aims: Examine the effect of two different calcium silicate-based cements on the viability and the odonto-/osteogenic potential of Stem Cells from Apical Papilla (SCAP).

    Material and method: 

    Isolated SCAPs from three healthy donors (donor I, II and III) were used and exposed for different concentration extracts of ProRoot® MTA and BiodentineTM for 21 days. Cell viability was studied using the neutral red cytotoxicity test. Osteogenic differentiation was analyzed by the alkaline phosphatase test (ALP).

    Results: 

    No difference in SCAPs viability was detected by the type of cements used, Biodentine or ProRoot MTA. However, material concentration could be associated with cells cytotoxicity.  Osteogenic differentiation was not based on the type of cement used but the environment conditions (aerobic/anaerobic) and the genetical background.

    Conclusions:

    The type of cement used in RET, Biodentine or MTA, showed similar effect on SCAPs viability and differentiation potential in vitro. Further studies should be performed to analyze their effect -in -vivo.

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  • 94.
    Abdalla, Souad
    Umeå University, Faculty of Medicine, Department of Medical and Translational Biology.
    HEALTH ECONOMIC EVALUATION OF THE IMPLEMENTATION OF FARICIMAB IN WET AGE-RELATED MACULAR DEGENERATION2024Independent thesis Advanced level (degree of Master (Two Years)), 20 credits / 30 HE creditsStudent thesis
  • 95.
    Abdallah Mohammed, Sara Abbas
    et al.
    Umeå University, Faculty of Social Sciences, Umeå School of Business and Economics (USBE), Business Administration.
    Parvin, Shaila
    Umeå University, Faculty of Social Sciences, Umeå School of Business and Economics (USBE), Business Administration.
    A Road to be Paved: How Can Foreign Born Women Entrepreneurs be Included in the Swedish Entrepreneurial Ecosystem: A Case Study on Novice Foreign Born Entrepreneurs in Sweden2021Independent thesis Advanced level (degree of Master (Two Years)), 20 credits / 30 HE creditsStudent thesis
    Abstract [en]

    Entrepreneurial ecosystem is made up of multiple participants, components, and actors. The entrepreneurial ecosystem in Sweden consists of various components, all of which contribute to the creation and enhancement of entrepreneurial experiences for novice entrepreneurs. Research on immigrants has been carried and published, emphasizing men as the primary group within the immigrant population. The contradictory point about women remaining in the shadows is still vital and valid. This research tries to describe and explain the inclusion of these novice immigrant female entrepreneurs into the entrepreneurial ecosystem. Based on a literature review on the entrepreneurial ecosystem, women's motives for starting a new venture, and the breakthrough process, a qualitative approach was deemed appropriate to understand the flow and dynamics of this inclusion process. The case study method was used as the research strategy for two different groups of actors in the entrepreneurial ecosystem. In-depth semi-structured interviews were conducted with two groups of people: The first group, business coaches, business developers, business consultants, and general managers who work on consulting and support projects for entrepreneurs. The second group consisted of foreign-born novice female entrepreneurs. The findings indicate that the obstacles to inclusion are more than just road paves. The most frequently addressed obstacles were those related to communication, cultural backgrounds, knowledge and training. Communication barriers prevent these entrepreneurs from engaging with other entrepreneurial ecosystem actors, resulting in exclusion. Another obstacle was the cultural background, which included social factors, language, norms, and beliefs. The final barrier was knowledge and training, which facilitated network building and provided entrepreneurs with the necessary information to establish and run their businesses. The analysis identified that obstacles and road pavers for the inclusion process are extending to all the actors included in this research; novice entrepreneurs must identify and build multiple ties that connect them to the other ecosystem actors, and the other actors must do the same to include these novice foreign born female entrepreneurs in the ecosystem. Communication for novice foreign-born female entrepreneurs, on the other hand, is to establish ties with other ecosystem actors, which will promote access to financing, consultancy, government rules and regulations, and training sessions. However, it was noted that ecosystem actors play an important role in the communication process and can turn it into a road paver. Another obstacle found through the study is the social and cultural influences that impede the communication process. For example, the paper identified language as a significant obstacle and the beliefs and norms that form these women's attitudes, and one of the significant attitudes is a lack of trust in government rules and regulations. Finally, knowledge and training are regarded as a communication tool that connects these novice immigrant female entrepreneurs to the other ecosystem actors, besides introducing them to the components of the entrepreneurial ecosystem like financing and funding. Since the paper focused on a small number of actors and ecosystem components, it was not easy to thoroughly define and justify the inclusion process. Further research could investigate the steps of the process and the participants, including other actors and ecosystem components not covered in this paper.

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    Diva Form
  • 96.
    Abdallah, Wissam
    Umeå University, Faculty of Arts, Department of historical, philosophical and religious studies.
    Det sistakorståget: Operation Barbarossa: En historiografisk studie om orsakerna till den tyska invasionen av Sovjetunionen2010Independent thesis Advanced level (degree of Master (One Year)), 10 credits / 15 HE creditsStudent thesis
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  • 97.
    Abdallah, Wissam
    Umeå University, Faculty of Arts, Department of historical, philosophical and religious studies.
    Vad är rättvisa?: En undersökning om vem eller vilka Platons teori riktar sig till2017Independent thesis Advanced level (degree of Master (One Year)), 10 credits / 15 HE creditsStudent thesis
    Abstract [en]

    Plato´s Republic is maybe the most widely read philosophical work of all times. It is the earliest surviving, systematic utopia in Europe´s history and continues to inspire people today. But who did Plato want to address with his work and why? In this paper I will discuss these issues. My thesis is that Plato wanted to direct his Republic to people, men and women, who have a good character and love wisdom in order to make them to think radically differently from the traditional norms. If these would-be philosophers could challenge the old-fashioned way of seeing things they could take the lead to establish a just society. I will also discuss critically two alternative approaches from other philosophers.

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  • 98.
    Abdelaziz, Amr Abdelaziz Badrawy
    et al.
    Umeå University, Faculty of Medicine, Department of Epidemiology and Global Health.
    Troeller, Kenan Craig
    Umeå University, Faculty of Medicine, Department of Epidemiology and Global Health.
    Cost-Effectiveness Analysis of Endovascular versus Open Repair of Ruptured Abdominal Aortic Aneurysm in Sweden2018Independent thesis Advanced level (degree of Master (Two Years)), 10 credits / 15 HE creditsStudent thesis
    Abstract [en]

    Background: Approximately 600 people die from ruptured abdominal aortic aneurism annually in Sweden. Abdominal aortic aneurysm (AAA) is a widening of the abdominal aorta. If a ruptured aortic aneurysm occurs (RAAA), it is a medical emergency and it is a life-threatening condition. The two interventions used to treat RAAA patients are known as the endovascular strategy (EVAR) and the open repair method (OR). Given the life-threatening nature of RAAA, mortality rates are quite high especially considering that this medical condition affects predominantly the elderly. Determining whether a patient is more suitable for EVAR or OR depends on —among other clinical factors— whether technical expertise and resources are available to perform EVAR. The Swedish Agency for Health and Technology Assessment (SBU) explain that it is currently unclear as to which of the two intervention is the cost-effective alternative in treating RAAA in Sweden. 

    Objective: The aim of this study is to evaluate whether the non-invasive EVAR (endovascular) or traditional surgery known as OR (open repair) is more cost-effective in treating RAAA in Sweden.

    Methods: A Cost-effectiveness analysis with healthcare provider perspective using secondary data from relevant peer-reviewed literature from Sweden, other European countries, Swedvascs' and Socialstyrelsens' registries. The model of choice for this evaluation is a decision tree. The target population is males and females who suffer from RAAA in Sweden ranging from ages 50 – 90+, the majority of which were >65. Two subgroups were analyzed; RAAA patients treated with EVAR  and RAAA patients treated with OR. Total RAAA patients n=178. EVAR n= 73. OR n= 105. The time horizon in the base-case is 90 days. The outcome measures are incremental cost-effectiveness ratio (ICER), QALYs and cost/QALY. A one-way deterministic sensitivity analyses, in addition to a probabilistic sensitivity analysis were performed in order to assess the level of confidence that may be associated with the conclusion of this economic evaluation

    Results: Results from the base-case analysis shows that EVAR's cost per QALY gained is SEK 715,823.82 with an ICER of SEK 1,113,499.44 per QALY gained. Results of the base-case analysis shows that EVAR is not cost-effective when considering the commonly accepted threshold of SEK 500,000 per QALY gained. Results of the deterministic sensitivity analyses show that under all suggested scenarios EVAR was not cost-effective. However, results of the probabilistic sensitivity analysis result shows that there is a considerable uncertainty around the cost-effectiveness of EVAR.

    Conclusion: EVAR is not cost-effective with marginal clinical benefits compared to OR. Since it is a high cost intervention which lacks national guidelines from "Socialstyrelsen", individual county councils in Sweden will likely have to make the decision individually if they want to adopt EVAR as a treatment method for RAAA. While RAAA is a very severe health condition it also has a low prevalence in Sweden meaning county councils with larger population centers, budgets and availability of technical expertise/equipment can still introduce EVAR to treat RAAA even if the cost-effectiveness analysis results exceed the commonly accepted threshold value of SEK 500,000 per QALY gained. Due to uncertainties vis-à-vis a lack of more conclusive data in a Swedish context, further investigation is required before recommending EVAR for subsidization. It would however be worth pursuing this end given the promise of EVAR as a non-invasive and more benign treatment method for patients. 

  • 99.
    Abdel-Aziz, Mahmoud I.
    et al.
    Dept of Respiratory Medicine, Amsterdam UMC, University of Amsterdam, Amsterdam, Netherlands; Dept of Clinical Pharmacy, Faculty of Pharmacy, Assiut University, Assiut, Egypt.
    Vijverberg, Susanne J.H.
    Dept of Respiratory Medicine, Amsterdam UMC, University of Amsterdam, Amsterdam, Netherlands.
    Neerincx, Anne H.
    Dept of Respiratory Medicine, Amsterdam UMC, University of Amsterdam, Amsterdam, Netherlands.
    Brinkman, Paul
    Dept of Respiratory Medicine, Amsterdam UMC, University of Amsterdam, Amsterdam, Netherlands.
    Wagener, Ariane H.
    Dept of Respiratory Medicine, Amsterdam UMC, University of Amsterdam, Amsterdam, Netherlands.
    Riley, John H.
    Respiratory Therapeutic Unit, GlaxoSmithKline, Stockley Park, United Kingdom.
    Sousa, Ana R.
    Respiratory Therapeutic Unit, GlaxoSmithKline, Stockley Park, United Kingdom.
    Bates, Stewart
    Respiratory Therapeutic Unit, GlaxoSmithKline, Stockley Park, United Kingdom.
    Wagers, Scott S.
    BioSci Consulting, Maasmechelen, Belgium.
    De Meulder, Bertrand
    European Institute for Systems Biology and Medicine, CIRI UMR5308, CNRS-ENS-UCBLINSERM, Lyon, France.
    Auffray, Charles
    European Institute for Systems Biology and Medicine, CIRI UMR5308, CNRS-ENS-UCBLINSERM, Lyon, France.
    Wheelock, Åsa M.
    Respiratory Medicine Unit, Dept of Medicine and Center for Molecular Medicine, Karolinska Institutet, Stockholm, Sweden; Dept of Respiratory Medicine and Allergy, Karolinska University Hospital, Stockholm, Sweden.
    Bansal, Aruna T.
    Acclarogen Ltd, St John’s Innovation Centre, Cambridge, United Kingdom.
    Caruso, Massimo
    Dept of Biomedical and Biotechnological Sciences, University of Catania, Catania, Italy.
    Chanez, Pascal
    Département des Maladies Respiratoires APHM, U1067 INSERM, Aix Marseille Université Marseille, Marseille, France.
    Uddin, Mohib
    AstraZeneca BioPharmaceuticals R&D, Gothenburg, Sweden.
    Corfield, Julie
    AstraZeneca R&D, Molndal, Sweden; Areteva R&D, Nottingham, United Kingdom.
    Horvath, Ildiko
    Dept of Public Health, Semmelweis University, National Koranyi Institute for Pulmonology, Budapest, Hungary.
    Krug, Norbert
    Fraunhofer Institute for Toxicology and Experimental Medicine Hannover, Hannover, Germany.
    Musial, Jacek
    Dept of Medicine, Jagiellonian University Medical College, Krakow, Poland.
    Sun, Kai
    Data Science Institute, South Kensington Campus, Imperial College London, London, United Kingdom.
    Shaw, Dominick E.
    Respiratory Research Unit, University of Nottingham, Nottingham, United Kingdom.
    Sandström, Thomas
    Umeå University, Faculty of Medicine, Department of Public Health and Clinical Medicine, Section of Medicine.
    Montuschi, Paolo
    Pharmacology, Faculty of Medicine, Catholic University of the Sacred Heart, Rome, Italy.
    Fowler, Stephen J.
    Division of Infection, Immunity and Respiratory Medicine, School of Biological Sciences, Faculty of Biology, Medicine and Health, University of Manchester, Manchester Academic Health Science Centre and NIHR Biomedical Research Centre, Manchester University Hospitals NHS Foundation Trust, Manchester, United Kingdom.
    Lutter, René
    Dept of Respiratory Medicine, Amsterdam UMC, University of Amsterdam, Amsterdam, Netherlands; Dept of Experimental Immunology, Amsterdam UMC, University of Amsterdam, Amsterdam, Netherlands.
    Djukanovic, Ratko
    NIHR Southampton Respiratory Biomedical Research Unit, Clinical and Experimental Sciences, and Human Development and Health, University of Southampton, Southampton, United Kingdom.
    Howarth, Peter
    NIHR Southampton Respiratory Biomedical Research Unit, Clinical and Experimental Sciences, and Human Development and Health, University of Southampton, Southampton, United Kingdom.
    Skipp, Paul
    Centre for Proteomic Research, Biological Sciences, University of Southampton, Southampton, United Kingdom.
    Sanak, Marek
    Dept of Internal Medicine, Jagiellonian University Medical College, Krakow, Poland.
    Adcock, Ian M.
    National Heart and Lung Institute, Imperial College London, Royal Brompton and Harefield NHS Trust, London, United Kingdom.
    Chung, Kian Fan
    National Heart and Lung Institute, Imperial College London, Royal Brompton and Harefield NHS Trust, London, United Kingdom.
    Sterk, Peter J.
    Dept of Respiratory Medicine, Amsterdam UMC, University of Amsterdam, Amsterdam, Netherlands.
    Kraneveld, Aletta D.
    Division of Pharmacology, Utrecht Institute for Pharmaceutical Sciences, Faculty of Science, Utrecht University, Utrecht, Netherlands.
    Maitland-Van der Zee, Anke H.
    Dept of Respiratory Medicine, Amsterdam UMC, University of Amsterdam, Amsterdam, Netherlands; Dept of Pediatric Respiratory Medicine, Emma Children’s Hospital, Amsterdam UMC, Amsterdam, Netherlands.
    A multi-omics approach to delineate sputum microbiome-associated asthma inflammatory phenotypes2022In: European Respiratory Journal, ISSN 0903-1936, E-ISSN 1399-3003, Vol. 59, no 1, article id 2102603Article in journal (Refereed)
    Abstract [en]

    A multi-omics approach revealed the underlying biological pathways in the microbiome-driven severe asthma phenotypes. This may help to elucidate new leads for treatment development, particularly for the therapeutically challenging neutrophilic asthma.

  • 100.
    Abdelhay, Amro Gaber
    Umeå University, Faculty of Medicine, Department of Epidemiology and Global Health.
    Antibiotic misuse in Egypt from the community pharmacists' perspective.: A study protocol.2019Independent thesis Advanced level (degree of Master (One Year)), 10 credits / 15 HE creditsStudent thesis
    Abstract [en]

    Introduction/Background: Antibiotic resistance (AR) has become a danger threats to all countries and regions in the world. Decreased effectiveness of antibiotics in treating some infections due to antibiotic resistance is leading to more suffering for patients, increased treatment costs, increased days of hospitalization as well as increasing morbidity and mortality. In order to tackle AR, a much more responsible use of antibiotics is needed including avoidance of overuse, overprescribing and any other type of inappropriate use of antibiotics. Egypt is one of the countries with high rate of antibiotic misuse- In the study that this study protocol is outlining, the reasons for misuse will be explored from the community pharmacists’ perspectives in order to suggest possible solutions.

    Objective: The general objective is to study factors contributing to antibiotic misuse in Egypt from the perspective of community pharmacists.

    Method: A cross sectional study will be conducted using structured questionnaire. Answers will be collected from community pharmacists in Fayoum governorate in Egypt whereafter data analysis will be done.

    Study work plan: It is intended that the study period altogether will be six months.

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