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  • 1. Ahlgren, Camilla
    et al.
    Molin, Margareta
    Umeå universitet, Medicinsk fakultet, Odontologi, Protetik. Umeå universitet, Medicinsk fakultet, Odontologi.
    Lundh, Thomas
    Nilner, Krister
    Levels of gold in plasma after dental gold inlay insertion.2007Inngår i: Acta odontologica Scandinavica, ISSN 1502-3850, Vol. 65, nr 6, 331-4 s.Artikkel i tidsskrift (Fagfellevurdert)
    Abstract [en]

    OBJECTIVE: Several studies have reported increased levels of gold (Au) in the blood of patients with dental gold restorations. This study analyzed gold levels in blood plasma before dental gold inlay insertion, 0-12 months after, and 15 years after. MATERIAL AND METHODS: Plasma samples from 9 patients were taken before and 0-10 months after gold inlay insertion. Fifteen years after gold inlay insertion, further blood samples taken from 8 of these patients were analyzed for gold using inductively coupled plasma mass spectrometry. An oral examination was also carried out before and 15 years after gold inlay insertion. RESULTS: Gold levels in plasma were significantly higher 0-12 months after gold inlay insertion than before treatment (p=0.008). No significant difference in gold plasma levels was found between 0-12 months after and 15 years after insertion (p=0.109), although there was a significant correlation between the number of gold alloy surfaces and the amount of gold in plasma 15 years after insertion (p=0.028). CONCLUSIONS: This study supports a dose-related release of gold into plasma from dental gold restorations, a release that appears to be stable over time.

  • 2. Berglund, A
    et al.
    Molin, M
    Umeå universitet, Medicinsk fakultet, Odontologi, Protetik.
    Mercury levels in plasma and urine after removal of all amalgam restorations: the effect of using rubber dams.1997Inngår i: Dental Materials, ISSN 0109-5641, Vol. 13, nr 5, 297-304 s.Artikkel i tidsskrift (Fagfellevurdert)
    Abstract [en]

    OBJECTIVE: The aim of the present study was to determine whether removal of all amalgam restorations might significantly affect mercury levels in plasma and urine and whether the use of rubber dams might reduce patient exposure to mercury during amalgam removal. METHODS: All amalgam restorations were removed from 18 subjects during a single treatment session in which a rubber dam was used and from 10 subjects when a rubber dam was not used. All amalgam restorations were removed by the same dentist using high-speed cutting, water coolant, and high-volume evacuation. The levels of mercury in plasma and urine were analyzed both before and during the subsequent twelve months after amalgam removal. In order to determine whether removal of all amalgam restorations might cause an exposure large enough to significantly increase the mercury levels in two indicator media for mercury exposure, i.e., plasma and urine, and to determine if the removal might cause a significant decrease in the mercury levels found over time, the one-tailed, paired Students' t-test was used. For each individual, the pre-removal levels were compared with both the levels found in plasma on d 1 and in urine on d 10, and also with the levels found 1 y after removal. Furthermore, in order to examine whether the use of rubber dams had any effect on the mercury levels found after removal, the changes in the mercury levels found were compared between the groups using the Wilcoxon-Mann-Whitney rank sum test. RESULTS: After removal of all amalgam restorations, only the non-rubber dam group showed significant increases in the mercury levels found in plasma (p = 0.012) and urine (p = 0.037). However, one year later, the mercury levels in plasma and urine had sunk significantly below the pre-removal levels for both groups. When the changes in the mercury levels found were compared between the groups, the non-rubber dam group showed a significantly higher increase of mercury in plasma than the rubber dam group the day after removal (p = 0.0010). Compared to the pre-removal mercury levels in plasma and urine, the levels found 1 y after removal of all amalgam restorations were on average 52 +/- 23% (range 4-89%) lower in plasma and 76 +/- 21% (range 20-94%) lower in urine. SIGNIFICANCE: The study showed that dental amalgam had a statistically significant impact on the mercury levels found in plasma and urine in the patients tested, and that the use of a rubber dam during removal of all amalgam restorations significantly reduced the peak of mercury in plasma following removal.

  • 3. Berglund, A
    et al.
    Molin, M
    Umeå universitet, Medicinsk fakultet, Odontologi, Protetik.
    Mercury vapor release from dental amalgam in patients with symptoms allegedly caused by amalgam fillings.1996Inngår i: European Journal of Oral Sciences, ISSN 0909-8836, Vol. 104, nr 1, 56-63 s.Artikkel i tidsskrift (Fagfellevurdert)
    Abstract [en]

    The aim of this study was to determine whether a group of patients with symptoms, self-related to their amalgam restorations, experienced an exposure to mercury vapor from their amalgam restorations that reached the range at which subtle symptoms have been reported in the literature. Furthermore, the aim was to determine whether the mercury exposure for these patients was significantly higher than for controls with no reported health complaints. The symptom group consisted of 10 consecutively selected patients from a larger group, referred by their physicians for investigation into any correlation between subjective symptoms and amalgam restorations. The control group consisted of 8 persons with no reported health complaints. The intra-oral release of mercury vapor was measured between 7:45 a.m. and 9:00 p.m. at intervals of 30-45 min, following a standardized schedule. The mercury levels in plasma, erythrocytes, and urine were also determined. The calculated daily uptake of inhaled mercury vapor, released from the amalgam restorations, was less than 5% of the daily uptake calculated at the lower concentration range given by the WHO (1991), at which subtle symptoms have been found in particularly sensitive individuals. The symptom group had neither a higher estimated daily uptake of inhaled mercury vapor, nor a higher mercury concentration in blood and urine than in the control group. The study provides no scientific support for the belief that the symptoms of the patients examined originated from an enhanced mercury release from their amalgam restorations.

  • 4. Bessing, C
    et al.
    Molin, M
    Umeå universitet, Medicinsk fakultet, Odontologi, Protetik.
    An in vivo study of glass ceramic (Dicor) inlays. Preliminary report.1990Inngår i: Acta Odontologica Scandinavica, ISSN 0001-6357, Vol. 48, nr 5, 351-7 s.Artikkel i tidsskrift (Fagfellevurdert)
    Abstract [en]

    For the purpose of evaluating the clinical quality of glass ceramic (Dicor) inlays 15 patients with 37 inlays were examined 1 to 22 months after placement. In addition to certain periodontal variables, the inlays were rated by two independent examiners using the California Dental Association (CDA) quality evaluation system. The results of the present study showed that dental plaque was seen less often on proximal surfaces with inlays than on homologous proximal surfaces. Three patients reported hypersensitivity of the dental pulp. The examination using the CDA criteria showed that 54% of the inlays had a slight color mismatch, and slightly roughened surfaces were occasionally seen (35.5%). In nearly 30% of the inlays there was visible evidence of ditching along the margins. At present, no judgement can be made about the longevity of ceramic inlays.

  • 5.
    Börlin, Niclas
    et al.
    Umeå universitet, Teknisk-naturvetenskapliga fakulteten, Institutionen för datavetenskap.
    Lindh, Tomas
    Umeå universitet, Medicinska fakulteten, Institutionen för odontologi, Protetik.
    An Implant-oriented method for dental digital subtraction radiography1999Inngår i: Computer Methods in Biomechanics & Biomedical Engineering — 2 / [ed] Middleton, J., Gordon and Breach Science Publishers , 1999, 705-712 s.Konferansepaper (Annet vitenskapelig)
  • 6.
    Börlin, Niclas
    et al.
    Umeå universitet, Teknisk-naturvetenskapliga fakulteten, Institutionen för datavetenskap.
    Lindh, Tomas
    Umeå universitet, Medicinska fakulteten, Institutionen för odontologi, Protetik.
    The threaded dental implant as a reference object for image alignment2001Inngår i: Computer Methods in Biomechanics and Biomedical Engineering, ISSN 1025-5842, Vol. 4, nr 5, 421-431 s.Artikkel i tidsskrift (Fagfellevurdert)
    Abstract [en]

    This paper presents a method that uses the threaded dental implant as a reference object for the inter-image alignment necessary for digital subtraction radiography. The implant is furthermore used to define a measurement coordinate system and to automate the placement of reference areas used for contrast correction. The method is intended for studies of diffuse bone density changes in the vicinity of the implant. The method is shown to be insensitive to large variations in exposure time and geometry, and is together with the contrast correction method of Ruttimann et al., able to detect clinically invisible simulated bone density changes.

  • 7.
    Danielsson, Karin
    et al.
    Umeå universitet, Medicinska fakulteten, Institutionen för odontologi, Oral diagnostik.
    Ebrahimi, Majid
    Umeå universitet, Medicinska fakulteten, Institutionen för odontologi, Oral diagnostik. Umeå universitet, Medicinska fakulteten, Institutionen för odontologi, Endodonti.
    Wahlin, Ylva-Britt
    Umeå universitet, Medicinska fakulteten, Institutionen för odontologi, Oral diagnostik. Umeå universitet, Medicinska fakulteten, Institutionen för odontologi, Protetik.
    Nylander, Karin
    Umeå universitet, Medicinska fakulteten, Institutionen för medicinsk biovetenskap, Patologi.
    Boldrup, Linda
    Umeå universitet, Medicinska fakulteten, Institutionen för medicinsk biovetenskap, Patologi.
    Reply to increased levels of COX-2 and oral lichen planus by P.D. Pigatto, F. Spaderi, G.P. Bombeccari, G. Guzzi by Danielsson et al2013Inngår i: Journal of the European Academy of Dermatology and Venereology, ISSN 0926-9959, E-ISSN 1468-3083, Vol. 27, nr 3, 395-396 s.Artikkel i tidsskrift (Fagfellevurdert)
  • 8.
    Danielsson, Karin
    et al.
    Umeå universitet, Medicinska fakulteten, Institutionen för odontologi, Oral diagnostik.
    Wahlin, Ylva-Britt
    Umeå universitet, Medicinska fakulteten, Institutionen för odontologi, Oral diagnostik. Umeå universitet, Medicinska fakulteten, Institutionen för odontologi, Protetik.
    Boldrup, Linda
    Umeå universitet, Medicinska fakulteten, Institutionen för medicinsk biovetenskap, Patologi.
    Nylander, Karin
    Umeå universitet, Medicinska fakulteten, Institutionen för medicinsk biovetenskap, Patologi.
    Decreased expression of ELF-3 indicating disturbed differentiation in oral lichen planus2012Inngår i: Oral Diseases, ISSN 1354-523X, E-ISSN 1601-0825, Vol. 18, nr Special Issue, Suppl. 1, 20-20 s.Artikkel i tidsskrift (Annet vitenskapelig)
  • 9. Derand, T
    et al.
    Molin, M
    Umeå universitet, Medicinska fakulteten, Institutionen för odontologi, Protetik.
    Kleven, E
    Haag, P
    Karlsson, S
    Bond strength of luting materials to ceramic crowns after different surface treatments2008Inngår i: European Journal of Prosthodontics and Restorative Dentistry, ISSN 0965-7452, Vol. 16, nr 1, 35-38 s.Artikkel i tidsskrift (Fagfellevurdert)
    Abstract [en]

    The aim of present study was to evaluate the effect of different pre-treatments of alumina and zirconia copings on the bond strength of different luting materials. Pull out tests was performed on 60 alumina and 80 zirconia copings. Randomly selected, copings were divided in groups of; i) un-treated alumina and zirconia copings, (n=20) ii) alumina and zirconia copings sandblasted with 50 or 110 µm alumina particles respectively (n=20), iii) zirconia copings treated with monolayer of glass pearls fused to the inner surface (n=20) , iv) zirconia copings treated with silanized glass pearls (n=10). Zinc phosphate, Panavia 21 and VarioLink II were used for cementation. Pull out tests were done in an Instron universal testing machine with a speed of 0.5 mm/min and fracture loads was measured in N. Untreated zirconia copings cemented with zinc phosphate showed significantly higher bond strength values compared to those with sandblasted surfaces. No difference was seen between untreated alumina copings and those with sandblasted surfaces. Sandblasting decreased bond strength of zirconia and alumina copings. Glass pearls increased bond strength of zirconia copings, which was even better after silanization. Variolink II in combination with alumina gave significantly lower bond strength.

  • 10. Derand, Tore
    et al.
    Molin, Margareta
    Umeå universitet, Medicinska fakulteten, Institutionen för odontologi, Protetik.
    Kvam, Ketil
    Bond strength of a composite luting agent to alumina ceramic surfaces.2006Inngår i: Acta Odontologica Scandinavica, ISSN 0001-6357, Vol. 64, nr 4, 227-30 s.Artikkel i tidsskrift (Fagfellevurdert)
    Abstract [en]

    OBJECTIVE: The purpose of this study was to evaluate the shear bond strength (SBS) of a dental luting agent to alumina ceramics after different surface pretreatment. MATERIAL AND METHODS: Specimens (n=50) of pressed blocks (10 x 0 x 5 mm) of alumina ceramic (Procera AllCeram) were divided into untreated specimens (AF) as provided by the manufacturer and polished specimens (AP). Five groups of specimens (n=5 x 10) with different surface pretreatments were prepared. Groups 1 and 2: AF and AP without any pretreatment; Group 3: AF treated with silane, (AF-s); Group 4: AF treated with RF plasma spray (AF-RF); Group 5: AF treated with low fusing porcelain (AF-p) glass pearls. Composite cylinders (5 x 5 mm) were cemented to the test specimens with a resin luting agent. The specimens were loaded to failure in shear mode using a universal testing machine. Recorded loads were used to calculate SBS in MPa. The results were analyzed using one-way ANOVA and the Tukey HSD multiple comparison test at alpha = 0.05. Scanning electron microscopic micrographs (SEM) were used to characterize surfaces of interest. RESULTS: Polished surfaces had significantly lower SBS (p < 0.05) compared with untreated specimens (AP vs AF). Silanated, non-polished surfaces (AF-s) revealed lower SBS, even though the result was not significantly different from that of AF-s without silane treatment. Plasma treatment improved SBS by a factor of 2 (p<0.05) and treatment with low-fusing porcelain micro pearls increased SBS by a factor of 3 compared to untreated surfaces (p<0.05). The layer of glass pearls did not exceed 5 microm (SEM). CONCLUSIONS: Within the limitation of the conditions of this study, treatment of alumina oxide ceramic surfaces with a plasma spray coating or a low-fusing porcelain pearl layer significantly increased the SBS of a resin luting agent to the ceramic surface.

  • 11. Derand, Tore
    et al.
    Molin, Margareta
    Umeå universitet, Medicinsk fakultet, Odontologi, Protetik.
    Kvam, Ketil
    Bond strength of composite luting cement to zirconia ceramic surfaces.2005Inngår i: Dental Materials, ISSN 0109-5641, Vol. 21, nr 12, 1158-62 s.Artikkel i tidsskrift (Fagfellevurdert)
    Abstract [en]

    OBJECTIVES: To evaluate the bond strength of dental resin agent to zirconia ceramic after surface pre-treatment with different techniques. METHODS: Specimens of hot isostatic pressed yttrium-oxide-partially-stabilized zirconia blocks (ZF) were fabricated (Procera Zircon, Nobel Biocare, Sweden) and compared to glossy dense zirconia blocks (ZG). Four groups of specimens with different surface treatment were prepared. Group I: ZF (n = 5) and ZG (n = 5) without any pre-treatment, Group II: ZF-s (n = 5) and ZG-s (n = 5) treated with silane solution, Group III: ZF-P (n = 10) and ZG-P (n = 10) treated with RF plasma spraying (hexamethyldisiloxane) using a reactor (Plasma Electronic, Germany), Group IV: ZF-p (n = 10) and ZG-p (n = 10) treated with micro pearls of low fusing porcelain (720 degrees C) on the surfaces. Composite cylinders (Charisma, Hereus Kulzer, Dormagen, Germany) were luted with Variolink II (Ivoclar-Vivadent, Schaan, Liechtenstein) to the test specimens. The specimens were then stored in air for 1 h before shear loading in a universal testing machine (LRX, Lloyd Instruments, Farnham, England) until failure. RESULTS: No statistical difference was found between the untreated ZF and ZG specimens (Group I) neither between the specimens treated with silane (Group II). Plasma spraying treatment improved bond strength by a factor of three (p < 0.001). Treatment with low fusing porcelain micro pearls increased the bond strength by a factor of 10 compared to untreated surfaces (p < 0.001). No significant difference was seen between the surfaces treated ZF-p and ZG-p specimens. The thickness of the glass pearls layer did not exceed 5 microm. SEM showed dense grain borders of ZF and a flat glossy texture of ZG. SIGNIFICANCE: Treatment of zirconia ceramic surfaces with plasma spraying or a low fusing porcelain pearl layer significantly increased the bond strength of resin cement to the ceramic surface.

  • 12.
    Ebrahimi, Majid
    et al.
    Umeå universitet, Medicinska fakulteten, Institutionen för odontologi, Endodonti.
    Lundqvist, L.
    Umeå universitet, Medicinska fakulteten, Institutionen för folkhälsa och klinisk medicin, Dermatologi och venereologi.
    Wahlin, Ylva-Britt
    Umeå universitet, Medicinska fakulteten, Institutionen för odontologi, Protetik.
    Nylander, Elisabet
    Umeå universitet, Medicinska fakulteten, Institutionen för medicinsk biovetenskap.
    Mucosal lichen planus a systemic disease requiring multidisciplinary care2012Inngår i: Oral Diseases, ISSN 1354-523X, E-ISSN 1601-0825, Vol. 18, nr Special Issue, Suppl. 1, 21-21 s.Artikkel i tidsskrift (Annet vitenskapelig)
  • 13. Gotfredsen, K
    et al.
    Carlsson, G E
    Jokstad, A
    Arvidson Fyrberg, K
    Berge, M
    Bergendal, B
    Bergendal, T
    Ellingsen, J-E
    Gunne, J
    Umeå universitet, Medicinsk fakultet, Odontologi, Protetik.
    Hofgren, M
    Holm, B
    Isidor, F
    Karlsson, S
    Klemetti, E
    Lang, N P
    Lindh, T
    Midtbø, M
    Molin, M
    Umeå universitet, Medicinsk fakultet, Odontologi, Protetik.
    Närhi, T
    Nilner, K
    Owall, B
    Pjetursson, B
    Saxegaard, E
    Schou, S
    Stokholm, R
    Thilander, B
    Tomasi, C
    Wennerberg, A
    Implants and/or teeth: consensus statements and recommendations.2008Inngår i: Journal of oral rehabilitation, ISSN 1365-2842, Vol. 35 Suppl 1, 2-8 s.Artikkel i tidsskrift (Fagfellevurdert)
    Abstract [en]

    In August 23-25, 2007, the Scandinavian Society for Prosthetic Dentistry in collaboration with the Danish Society of Oral Implantology arranged a consensus conference on the topic 'Implants and/or teeth'. It was preceded by a workshop in which eight focused questions were raised and answered in eight review articles using a systematic approach. Twenty-eight academicians and clinicians discussed the eight review papers with the purpose to reach consensus on questions relevant for the topic. At the conference the consensus statements were presented as well as lectures based on the review articles. In this article the methods used at the consensus workshop are briefly described followed by the statements with comments.

  • 14.
    Gunne, Johan
    et al.
    Umeå universitet, Medicinsk fakultet, Odontologi, Protetik.
    Nyström, Elisabeth
    Umeå universitet, Medicinsk fakultet, Odontologi, Käkkirurgi.
    Kahnberg, Karl-Erik
    Bone grafts and implants in the treatment of the severely resorbed maxillae: a 3-year follow-up of the prosthetic restoration.1995Inngår i: International Journal of Prosthodontics, ISSN 0893-2174, Vol. 8, nr 1, 38-45 s.Artikkel i tidsskrift (Fagfellevurdert)
    Abstract [en]

    Thirty patients with severely resorbed maxillae were treated in a one-stage procedure using bone graft and implant placement. A horseshoe-shaped bone graft was taken from the iliac wing and fixed to the residual maxillary ridge using titanium implants, which supported the prostheses placed after a 6-month healing period. The material constituted two groups: a development group, the first 10 patients; and a routine group, the following 20 patients. At the 3-year follow-up, the implant survival was 87.5% and the prosthesis stability was 100% in the routine group. The probing depth did not change during the follow-up period, while the grafted region decreased in volume during the first postoperative year. The patients reported improved chewing ability and improved life quality. Very few technical and prosthodontic complications occurred.

  • 15. Holm, Charlotta
    et al.
    Tidehag, Per
    Tillberg, Anders
    Molin, Margareta
    Umeå universitet, Medicinsk fakultet, Odontologi, Protetik. Umeå universitet, Medicinsk fakultet, Odontologi.
    Longevity and quality of FPDs: a retrospective study of restorations 30, 20, and 10 years after insertion.2003Inngår i: International Journal of Prosthodontics, ISSN 0893-2174, Vol. 16, nr 3, 283-9 s.Artikkel i tidsskrift (Fagfellevurdert)
    Abstract [en]

    PURPOSE: The aim of this retrospective study was to investigate the longevity and clinical performance of fixed partial dentures (FPD) 30, 20, and 10 years after insertion. MATERIALS AND METHODS: A total of 289 FPDs were inserted in 1966/67, 1976/77, and 1986/87. For patients with FPDs presumably still in function, an evaluation according to the CDA criteria was made. RESULTS: For 64 of the FPDs (22%), no information was available. Seventy-nine patients with 94 FPDs (33%) were clinically examined, and 44 of the FPDs (15%) were reported to be still in function by the patients' current clinicians. The remaining 87 FPDs (30%) were considered lost to follow-up. These FPDs had either been removed for various reasons--in most cases dental caries, lost retention, or fractured abutment teeth--or the patient could not be contacted. Eighty-four percent of the FPDs inserted in 1966/67 were still in function after 20 years, compared to 64% of those inserted in 1976/77. Apart from an increase in wear and discoloration, the oldest FPDs had excellent marginal fit and anatomic shape. CONCLUSION: The survival rate of 30-year-old FPDs was high; 53% remained in function after 30 years. Based on the CDA criteria, 78% of the restorations were rated satisfactory in all subgroups. The FPDs placed in 1966/67 obtained the highest ratings in color, anatomy, and margin integrity.

  • 16.
    Håff, Anna
    et al.
    Umeå universitet, Medicinska fakulteten, Institutionen för odontologi, Odontologisk materialvetenskap.
    Löf, Hanna
    Umeå universitet, Medicinska fakulteten, Institutionen för odontologi, Odontologisk materialvetenskap.
    Gunne, Johan
    Umeå universitet, Medicinska fakulteten, Institutionen för odontologi, Protetik.
    Sjögren, Göran
    Umeå universitet, Medicinska fakulteten, Institutionen för odontologi, Odontologisk materialvetenskap.
    A retrospective evaluation of zirconia-fixed partial dentures in general practices: an up to 13-year study2015Inngår i: Dental Materials, ISSN 0109-5641, E-ISSN 1879-0097, Vol. 31, nr 2, 162-170 s.Artikkel i tidsskrift (Fagfellevurdert)
    Abstract [en]

    Objectives: To evaluate zirconia-based fixed partial dentures (FPDs) after more than 8 years in clinical service.

    Methods: Patients treated between 2000 and 2004 with zirconia FPDs were identified from the records of a manufacturer of FPD substructures. Of the 45 patients who met the inclusion criteria 30 attended the appointment and 33 FPDs were evaluated using modified California Dental Association (CDA) criteria. In addition, plaque and the bleeding index were registered. Patient satisfaction with the restorations was evaluated using a 10-point visual analog scale (VAS).

    Results: All the FPDs were made using CAD/CAM and hot isostatic pressed yttria-tetragonal zirconia polycrystal (HIPed Y-TZP) ceramic (Denzir) and were placed within general practices. The mean observation period was 9.6 ± 1.6 years (range 3.0–13.1 years). The CDA rating was 90% satisfactory for the surface. Corresponding figures for anatomic form, color and margin integrity were 94%, 100% and 94%, respectively. Regarding surface three (9.7%) FPDs exhibited veneer chipping and were rated ‘not acceptable’. For margin integrity two (6.5%) were rated ‘not acceptable’ because of caries. For anatomic form two (6.1%) were rated ‘not acceptable’ due to two lost FPDs. No significant differences were seen between the FPDs and controls for plaque and bleeding. The Kaplan–Meier survival rate (still in clinical function) was 94%, the success rate (technical events accounted for) 91% and (biological events accounted for) 73%. Based on the VAS the mean value for patient satisfaction was 9.3 ± 1.2.

    Significance: Ninety-four percent of the FPDs were still in clinical function. HIPed Y-TZP could serve as an alternative for FPD treatments similar to those in the current study.

  • 17. Karlsson, S
    et al.
    Molin, M
    Umeå universitet, Medicinsk fakultet, Odontologi, Protetik.
    Effects of gold and bonded ceramic inlays on the ability to perceive occlusal thickness.1995Inngår i: Journal of Oral Rehabilitation, ISSN 0305-182X, Vol. 22, nr 1, 9-13 s.Artikkel i tidsskrift (Fagfellevurdert)
    Abstract [en]

    Any crown or inlay preparation will be accompanied with pulpal involvement and possible altered biomechanical and/or viscoelastic properties concerning the treated tooth. This study was aimed to assess this influence in terms of differences in interocclusal discrimination threshold value, before and after rehabilitation with gold inlays and by composite resin bonded ceramic inlays. Twenty patients were included and treated with one gold and three ceramic inlays each. For purposes of determining the discrimination threshold between the inlays and antagonizing teeth, plastic foils of different thicknesses were used. Each inlay position, as well as a pair of control teeth, were tested before and after treatment. Before rehabilitation an interocclusal and discrimination threshold of 24 microns at the level of 80% right answers were determined. Treatment with inlays, however, resulted in a significantly different and increased threshold for every tooth/inlays combination. No significant differences between the sessions were recorded for the control teeth. It could be concluded that, in the short term, an oral rehabilitation with inlays and in particular bonded inlays will influence mechanosensitive afferents.

  • 18. Karlsson, S
    et al.
    Molin, M
    Umeå universitet, Medicinsk fakultet, Odontologi, Protetik.
    Myrvold, T
    Flexural strength of two electro-plated dental ceramics.1994Inngår i: Acta Odontologica Scandinavica, ISSN 0001-6357, Vol. 52, nr 5, 290-3 s.Artikkel i tidsskrift (Fagfellevurdert)
    Abstract [en]

    This study aimed to investigate the influence on flexural strength of electro-plating two dental porcelains, Vita Omega and Vita Omega 800. The porcelains were treated in accordance with the manufacturer's instructions, and the specimens were produced following the ISO 6872 standard for rectangular bars. Specimens were divided into three groups, of which none, one, or three of the surfaces were plated with a thin layer of gold. Flexural strength was tested with a three-point bending test. Ten specimens were tested for each combination of porcelain and plating, for a total of 60 test pieces. For both porcelains, a significantly higher flexural strength was found for the specimens furnished with a gold layer. The number of covered surfaces did not significantly influence the tested strength. This increase in strength is most likely due to decreased crack initiation and fracture propagation after the covering of random defects in the porcelain. A better stress distribution might also be anticipated and partly explain the results.

  • 19.
    Kou, Wen
    et al.
    Umeå universitet, Medicinska fakulteten, Institutionen för odontologi, Odontologisk materialvetenskap.
    Molin, Margareta
    Umeå universitet, Medicinska fakulteten, Institutionen för odontologi, Protetik.
    Sjögren, Göran
    Umeå universitet, Medicinska fakulteten, Institutionen för odontologi, Odontologisk materialvetenskap.
    Surface roughness of five different dental ceramic core materials after grinding and polishing2006Inngår i: Journal of Oral Rehabilitation, ISSN 0305-182X, E-ISSN 1365-2842, Vol. 33, nr 2, 117-124 s.Artikkel i tidsskrift (Fagfellevurdert)
    Abstract [en]

    In clinical practice, core materials can be exposed after adjustments are made to previously-luted all-ceramic restorations. The purpose of this study was to evaluate the surface roughness of five different dental ceramic core materials after grinding and polishing. Five different ceramic core materials, Vita In-Ceram Alumina, Vita In-Ceram Zirconia, IPS Empress 2, Procera AllCeram, and Denzir were evaluated. Vita Mark II was used as a reference material. The surface roughness, Ra value (mum), was registered using a profilometer. The measurements were made before and after grinding with diamond rotary cutting instruments and after polishing with the Sof-Lex system. The surface of representative specimens was evaluated qualitatively using scanning electron microscopy (SEM). Results were statistically analysed using analysis of variance (anova) supplemented with Scheffe's and Bonferroni multiple-comparison tests. Before grinding, Procera AllCeram and Denzir had the smoothest surfaces, while IPS Empress 2 had the coarsest. After grinding, all materials except IPS Empress 2 became coarser. Polishing with Sof-Lex provided no significant (P > 0.05) differences between Denzir, Vita Mark II and IPS Empress 2 or between Procera AllCeram and In-Ceram Zirconia. There were no significant differences (P > 0.05) either between the ground and the polished Procera AllCeram or In-Ceram Alumina specimens. Polishing of Denzir, IPS Empress 2 and In-Ceram Zirconia made the surfaces smoother compared with the state after grinding, whereas the polishing effect on Procera AllCeram and In-Ceram Alumina was ineffective. The findings of the SEM evaluation were consistent with the profilometer readings.

  • 20. Lindh, T
    et al.
    Gunne, J
    Tillberg, A
    Molin, M
    Umeå universitet, Medicinsk fakultet, Odontologi, Protetik.
    A meta-analysis of implants in partial edentulism.1998Inngår i: Clinical Oral Implants Research, ISSN 0905-7161, Vol. 9, nr 2, 80-90 s.Artikkel i tidsskrift (Fagfellevurdert)
    Abstract [en]

    A meta-analytic technique was used to estimate the survival of implants supporting bridges or single crowns in partially edentulous patients. A survey of the literature revealed 66 studies, published between 1986 and 1996. Nine studies on single implants and 10 studies on fixed partial dentures met the inclusion criteria for the meta-analysis. Data from a total of 2686 implants, 570 single crowns (SC) and 2116 in fixed partial dentures (FPD), were analyzed. In order to calculate annual survival rates for individual studies a life-table analysis was conducted. Maximum follow-up time ranged between 1 and 8 years. After 1 year the success rate was calculated to be at least 85.7% for FPD and 97.2% for SC. When the results from the FPD studies were pooled the survival rate was 93.6% after 6-7 years. The corresponding value for SC was 97.5%.

  • 21. Lindh, Tomas
    et al.
    Bäck, Tomas
    Nyström, Elisabeth
    Umeå universitet, Medicinsk fakultet, Odontologi, Käkkirurgi.
    Gunne, Johan
    Umeå universitet, Medicinsk fakultet, Odontologi, Protetik.
    Implant versus tooth-implant supported prostheses in the posterior maxilla: a 2-year report.2001Inngår i: Clinical Oral Implants Research, ISSN 0905-7161, E-ISSN 1600-0501, Vol. 12, nr 5, 441-449 s.Artikkel i tidsskrift (Fagfellevurdert)
    Abstract [en]

    When implants are used for restoration of a jaw with a residual dentition, the possibility of combining implants with natural abutments may be considered. In a longitudinal comparative study, 26 patients (15 women & 11 men, age 49-84 years) with residual anterior dentitions were treated with two different designs of fixed partial dentures bilaterally in the posterior maxilla. On one side the reconstruction was supported by implants only, while on the contralateral side an implant and a tooth in combination were used. The patients were followed at intervals of 3, 6, 12 and 24 months after loading of the implants. 95 implants were placed, of which 11 non-loaded. A total of 10 implants failed, 7 prior to loading and three within the first three months of service (88.0+/-SE 6.7% cumulative survival for tested implants after two years' follow-up). There was no difference in failure rate for the implants in the two different prosthesis designs. The total mean loss of marginal bone height close to the implants was within acceptable standards, but was more pronounced at the implants not combined with teeth. The results indicate a correlation between the prosthesis design and the loss of marginal bone.

  • 22.
    Lundgren, Stefan
    et al.
    Umeå universitet, Medicinsk fakultet, Odontologi, Käkkirurgi.
    Nyström, Elisabeth
    Umeå universitet, Medicinsk fakultet, Odontologi, Käkkirurgi.
    Nilson, Hans
    Umeå universitet, Medicinsk fakultet, Odontologi, Protetik.
    Gunne, Johan
    Umeå universitet, Medicinsk fakultet, Odontologi, Protetik.
    Lindhagen, O
    Bone grafting to the maxillary sinuses, nasal floor and anterior maxilla in the atrophic edentulous maxilla. A two-stage technique.1997Inngår i: International Journal of Oral and Maxillofacial Surgery, ISSN 0901-5027, Vol. 26, nr 6, 428-434 s.Artikkel i tidsskrift (Fagfellevurdert)
    Abstract [en]

    This study presents the results from 20 consecutive patients treated with an autogenous bone graft from the iliac crest. In ten patients the graft was placed in the maxillary sinuses and the floor of the nose (inlay group). Ten patients, in addition to the inlay graft, had a corticocancellous bone block secured with mini-screws to the anterior maxillary ridge (inlay/onlay group). Endosteal implants (Brånemark) were placed six months after surgery. A total of 136 implants were placed, of which eight failed to integrate during the six-month healing period. A further 15 implants were lost during the follow-up period. For the inlay group the average follow-up period was 22 months and for the inlay/onlay group 19 months. Donor site morbidity was significantly less when iliac bone was harvested with a trephine (inlay group) than in patients treated with our routine procedure for bone harvesting (inlay/onlay group). Surgical technique, donor site morbidity, implant survival and patient acceptance are presented.

  • 23.
    Lundgren, Stefan
    et al.
    Umeå universitet, Medicinska fakulteten, Institutionen för odontologi, Käkkirurgi. Umeå universitet, Medicinska fakulteten, Institutionen för odontologi.
    Nyström, Elisabeth
    Umeå universitet, Medicinska fakulteten, Institutionen för odontologi, Käkkirurgi. Umeå universitet, Medicinska fakulteten, Institutionen för odontologi.
    Sennerby, Lars
    Sjöström, Mats
    Brechter, Magnus
    Umeå universitet, Medicinska fakulteten, Institutionen för odontologi, Käkkirurgi.
    Nilson, Hans
    Öberg, Sven
    Lundqvist, Peter
    Jungner, Måns
    Umeå universitet, Medicinska fakulteten, Institutionen för odontologi, Käkkirurgi.
    Tidehag, Per
    Gunne, Johan
    Umeå universitet, Medicinska fakulteten, Institutionen för odontologi, Protetik.
    Rekonstruktiv käkkirurgi 2: Behandling av den tandlösa atrofiska maxillan2008Inngår i: Tandläkartidningen, ISSN 0039-6982, Vol. 100, nr 5, 72-73 s.Artikkel i tidsskrift (Annet (populærvitenskap, debatt, mm))
  • 24.
    Molin, M
    Umeå universitet, Medicinsk fakultet, Odontologi, Protetik.
    Mercury release from dental amalgam in man. Influences on selenium, glutathione peroxidase and some other blood and urine components.1990Inngår i: Swedish dental journal. Supplement, ISSN 0348-6672, Vol. 71, 1-122 s.Artikkel i tidsskrift (Fagfellevurdert)
  • 25.
    Molin, M
    et al.
    Umeå universitet, Medicinsk fakultet, Odontologi, Protetik.
    Bergman, B
    Ericson, A
    A clinical evaluation of conical crown retained dentures.1993Inngår i: The Journal of prosthetic dentistry (Print), ISSN 0022-3913, Vol. 70, nr 3, 251-6 s.Artikkel i tidsskrift (Fagfellevurdert)
    Abstract [en]

    In an uncontrolled retrospective recall study of 57 patients treated with conical crown retained dentures, 60 restorations (37 in the maxillae and 23 in the mandible jaw) with a mean wearing time of 30.1 months (range 4 to 76) were evaluated. Of the 248 abutments, eight (3.2%) had been lost. Clinically healthy mucosa was seen in 35 jaws. The marginal fit of the copings was judged to be good. No caries or new restorations were observed in 44 patients. Thirteen patients had 19 surfaces with new restorations and 20 surfaces with caries lesions. Of these 39 surfaces, 38 were located subgingivally.

  • 26.
    Molin, M
    et al.
    Umeå universitet, Medicinsk fakultet, Odontologi, Protetik.
    Bergman, B
    Marklund, S L
    Schütz, A
    Skerfving, S
    Mercury, selenium, and glutathione peroxidase before and after amalgam removal in man.1990Inngår i: Acta Odontologica Scandinavica, ISSN 0001-6357, Vol. 48, nr 3, 189-202 s.Artikkel i tidsskrift (Fagfellevurdert)
    Abstract [en]

    In 10 healthy persons all amalgam fillings were replaced with gold inlays. Blood and urinary levels were measured on 10 occasions during a 4-month period before and a 12-month period after amalgam removal. These variables were also measured three times in 10 healthy controls. A strong statistically significant relation was found between plasma mercury values and both the total number of amalgam surfaces (r = 0.71, p = 0.0006) and the total surface area of the fillings (r = 0.73, p = 0.0004). In the immediate postremoval phase plasma mercury rose three- to four-fold, whereas the urinary and erythrocyte mercury rose about 50%. These peak values declined to the preremoval level at about 1 month. Twelve months after the removal the plasma and urinary mercury levels were significantly reduced to 50% and 25%, respectively, of the initial values for the experimental group. Apart from the significantly lower plasma selenium values 5 and 10 days after removal no significant differences were found with regard to plasma selenium or erythrocyte glutathione peroxidase either within or between the experimental and the control groups. A large number of supplementary biochemical analyses did not show any influence on organ functions or any differences between the groups before or after the amalgam removal. Amalgam fillings considerably contributed to the plasma and urinary mercury levels.

  • 27.
    Molin, M
    et al.
    Umeå universitet, Medicinsk fakultet, Odontologi, Protetik.
    Bergman, B
    Marklund, S L
    Schütz, A
    Skerfving, S
    The influence of dental amalgam placement on mercury, selenium, and glutathione peroxidase in man.1990Inngår i: Acta Odontologica Scandinavica, ISSN 0001-6357, Vol. 48, nr 4, 287-95 s.Artikkel i tidsskrift (Fagfellevurdert)
    Abstract [en]

    Amalgam restorations were inserted in eight healthy persons, previously unprovided with dental restorations, who had several severe carious lesions. The mean number of surfaces restored were 16.1 (range, 11 to 22). The total mean calculated amount of mercury inserted was 2.9 g (range, 1.5 to 4.3 g). Blood and urinary levels were measured on seven occasions during a 4-month period before and a 3-month period after amalgam placement. One and 3 months after placement, the P-mercury mean values were almost equal to the preplacement values (3.3 nmol/l). After placement U-mercury increased continuously; 3 months after placement a statistically significantly higher (p less than 0.05) mean U-mercury value (0.58 nmol/mmol creatinine) was found compared with the mean preplacement value (0.34 nmol/mmol creatinine). No statistically significant correlation was found between the P- and U-mercury concentrations and the total number of amalgam surfaces. Selenium levels in plasma and urine and erythrocyte glutathione peroxidase showed no systematic change of pattern. The results show that the insertion of amalgam fillings contributed to the U-mercury concentration, but apparently even more extensive amalgam therapy and/or longer exposure periods are needed to affect the P-mercury concentration. No negative effects on the P- and U-selenium or the erythrocyte glutathione peroxidase levels could be found during the 3 months immediately after an extensive amalgam placement. The supplementary blood and urine analyses were not influenced by the insertion of amalgam fillings.

  • 28.
    Molin, M
    et al.
    Umeå universitet, Medicinsk fakultet, Odontologi, Protetik.
    Karlsson, S
    A 3-year clinical follow-up study of a ceramic (Optec) inlay system.1996Inngår i: Acta Odontologica Scandinavica, ISSN 0001-6357, Vol. 54, nr 3, 145-9 s.Artikkel i tidsskrift (Fagfellevurdert)
    Abstract [en]

    To evaluate the clinical quality of ceramic (Optec) inlays, the inlay production of 10 dentists, served by 3 dental laboratories, was examined independently by 2 calibrated examiners. Of the 57 patients with 205 inlays participating in the first examination, 47 patients with 145 remaining inlays participated in the 3-year follow-up reexamination. For 14 of the participants in the reexamination, altogether 21 inlays had fractured. The mean time in service before fracture was 26.4 months (range, 12-53 months). The inlays were rated using the California Dental Association (CDA) quality evaluation system. This examination showed that the mismatch of color had increased from the first examination to the reexamination and registered slightly roughened surfaces. As to anatomic form, a reduced number of inlays did not receive an excellent CDA rating at the reexamination. Visible evidence of ditching along the margin had increased by almost 50%, and an apparent discoloration of the margin between the restoration and the tooth structure was seen in 73% of the reexamined inlays, compared with 7% at the first examination.

  • 29.
    Molin, M
    et al.
    Umeå universitet, Medicinsk fakultet, Odontologi, Protetik.
    Karlsson, S
    A clinical evaluation of the Optec inlay system.1992Inngår i: Acta Odontologica Scandinavica, ISSN 0001-6357, Vol. 50, nr 4, 227-33 s.Artikkel i tidsskrift (Fagfellevurdert)
    Abstract [en]

    To evaluate the clinical quality of ceramic (Optec) inlays, the inlay production of 10 dentists, served by 3 dental laboratories, was examined independently by 2 calibrated examiners. A total of 57 patients with 205 inlays (mean age, 8.1 months) were examined 1 to 32 months after placement by means of using a slightly modified form of the California Dental Association criteria. Periodontal variables such as plaque index, gingival index, and margin index were also recorded. Eight patients reported postoperative but not persistent hypersensitivity in relation to the Optec therapy. No differences between Optec proximal surfaces and homologous control surfaces were seen with regard to plaque or bleeding on probing. The examination using the CDA criteria showed that 59% of the inlays had a slight color mismatch. Slightly roughened surfaces were most common (86%). As to anatomic form and margin integrity, 24% and 67%, respectively, of the inlays were rated excellent. A difference between the dentist with regard to the clinical quality of the inlay treatment procedure was seen. The present results cannot allow a definitive judgement with regard to the long-term clinical quality of the Optec inlay system but will serve as a base for further studies.

  • 30.
    Molin, M
    et al.
    Umeå universitet, Medicinsk fakultet, Odontologi, Protetik.
    Karlsson, S
    The fit of gold inlays and three ceramic inlay systems. A clinical and in vitro study.1993Inngår i: Acta Odontologica Scandinavica, ISSN 0001-6357, Vol. 51, nr 4, 201-6 s.Artikkel i tidsskrift (Fagfellevurdert)
    Abstract [en]

    Four inlay systems--gold, Cerec, Mirage, and Empress inlays--were evaluated for their adaptation to stone die and clinically to the tooth by means of a replica technique. Twenty inlays of each system were placed on premolars and molars in the lower jaw. A microscope was used to measure the adaptation at the approximal margin, at the inner axial wall, and at the occlusal cavosurface area. An overall better fit was observed for the gold inlays than for the ceramic inlays. When the different measuring locations were compared, a better fit was found for the occlusal area. The greatest discrepancies were recorded for the Cerec inlays, whereas the Mirage and Empress inlays were comparable.

  • 31.
    Molin, M
    et al.
    Umeå universitet, Medicinsk fakultet, Odontologi, Protetik.
    Marklund, S
    Bergman, B
    Bergman, M
    Stenman, E
    Plasma-selenium, glutathione peroxidase in erythrocytes and mercury in plasma in patients allegedly subject to oral galvanism.1987Inngår i: Scandinavian journal of dental research, ISSN 0029-845X, Vol. 95, nr 4, 328-34 s.Artikkel i tidsskrift (Fagfellevurdert)
    Abstract [en]

    Twelve patients with subjective symptoms, ascribed by the patients themselves to mercury released from dental restorations, were investigated. In addition to a general dental examination the following parameters were registered: the total number of amalgam surfaces in the mouth; potential and polarization of existing and accessible dental metallic restorations for calculation of intraoral currents. As regards the highest calculated intraoral current for each individual there was a statistically significant difference between the patient group and a control group consisting of 12 persons. An analysis of the amount of selenium, glutathione-peroxidase and mercury in the blood showed no differences between the patient and the control group. However, a statistically significant positive correlation could be seen between the total number of amalgam surfaces and the plasma-mercury level for patients and controls pooled together. The numerous other blood parameters analyzed did not reveal any differences between the groups.

  • 32.
    Molin, M
    et al.
    Umeå universitet, Medicinsk fakultet, Odontologi, Protetik.
    Marklund, S L
    Bergman, B
    Nilsson, B
    Mercury, selenium, and glutathione peroxidase in dental personnel.1989Inngår i: Acta Odontologica Scandinavica, ISSN 0001-6357, Vol. 47, nr 6, 383-90 s.Artikkel i tidsskrift (Fagfellevurdert)
    Abstract [en]

    Eighteen persons, dentists and nurses, with urinary mercury levels higher than the group median value of all dental personnel in the country of Västerbotten were compared with a group consisting of 15 persons with low urinary mercury levels working in the same clinics. A statistically significant difference between the high urinary mercury group and the low urinary mercury group could be seen in the plasma mercury level. In each group a statistically significant relation could be seen between the plasma mercury level and the total number of amalgam surfaces. The two groups did not differ with regard to the levels of plasma selenium and erythrocyte glutathione peroxidase, and no correlation between these two variables and the plasma mercury levels could be found. To evaluate organ functions, a large number of supplementary analyses were performed. These analyses did not indicate any influence on organ functions. Although the persons in the present study were occupationally exposed to mercury, none of the biologic variables analyzed seemed to be affected. Even among dental personnel who handle amalgam professionally the number of amalgam surfaces is a major contributory factor to the P-mercury level.

  • 33.
    Molin, M
    et al.
    Umeå universitet, Medicinsk fakultet, Odontologi, Protetik.
    Schütz, A
    Skerfving, S
    Sällsten, G
    Mobilized mercury in subjects with varying exposure to elemental mercury vapour.1991Inngår i: International Archives of Occupational and Environmental Health, ISSN 0340-0131, Vol. 63, nr 3, 187-92 s.Artikkel i tidsskrift (Fagfellevurdert)
    Abstract [en]

    In a mercury mobilization test, 0.3 g of the complexing agent sodium 2,3-dimercaptopropane-1-sulfonate (DMPS) was given orally to 10 workers with moderate occupational exposure to elemental mercury vapour, to 8 dentists with slight exposure, to 18 matched controls, and to 5 referents without amalgam fillings. In the workers, DMPS caused an increase in 24-h urinary mercury excretion by a factor of 10; in the dentists, 5.9; in the controls, 5.3; and in the amalgam-free referents, 3.8. Of the mercury excreted during 24 h, 59% appeared during the first 6 h. Close, albeit non-linear, associations were found between mobilized mercury and the premobilization mercury levels in plasma and urine, but not with the duration of occupational exposure or the rough estimate of the integrated function of blood levels vs time. The present data indicate that mercury mobilized after a single DMPS dose in close connection with exposure is mainly an index of recent exposure and is not significantly affected by slow body pools or long-term exposure.

  • 34.
    Molin, Margareta K
    et al.
    Umeå universitet, Medicinska fakulteten, Institutionen för odontologi, Protetik.
    Karlsson, Stig L
    Five-year clinical prospective evaluation of zirconia-based Denzir 3-unit FPDs2008Inngår i: International Journal of Prosthodontics, ISSN 0893-2174, E-ISSN 1139-9791, Vol. 21, nr 3, 223-227 s.Artikkel i tidsskrift (Fagfellevurdert)
    Abstract [en]

    Purpose: The aim of this prospective study was to evaluate the clinical performance of fully sintered hot isostatic pressed yttria-partially-stabilized zirconia (Denzir) 3-unit fixed partial dentures (FPDs).

    Materials and Methods: Nineteen 3-unit FPDs were placed in 18 patients. Ten FPDs were placed in the maxilla and 9 in the mandible. Two calibrated examiners evaluated the FPDs independently 1 week (baseline), 1 year, 3 years, and 5 years after placement using the California Dental Association quality evaluation system.

    Results: All FPDs were intact at the 5-year examination. One FPD lost retention after 12 months but remained intact; it was recemented and is still in function after 5 years. All FPDs were rated satisfactory over 5 years. No changes were seen in terms of color and anatomic form. The number of slightly rough or pitted occlusal surfaces increased approximately 30% over 5 years. Visible evidence of ditching along the margin increased over time, but only for those FPDs luted with zinc phosphate cement.

    Conclusion: The 5-year results indicate that yttria-partially-stabilized zirconia 3-unit FPDs with anatomically designed frameworks are promising prosthetic alternatives, even in the premolar and molar regions. However, for all-ceramic FPDs with more units in function, further studies are necessary.

  • 35.
    Molin, Margareta
    et al.
    Umeå universitet, Medicinsk fakultet, Odontologi, Protetik.
    Onesti, MP
    Pettersson, TB
    Dérand, TB
    Three-dimensional finite element analyses of all-ceramic posterior fixed partial dentures with different designs.2007Inngår i: The International Journal of Prosthodontics, Vol. 20, nr 1, 89-91 s.Artikkel i tidsskrift (Fagfellevurdert)
    Abstract [en]

    The aim was to evaluate the influence on the stress distribution patterns in and the magnitude of stresses on fixed partial dentures (FPDs) under different anatomic and design conditions. Three-dimensional finite element models of posterior 3-unit all-ceramic FPDs were created with and without periodontal ligaments, with different radii of curvature at the embrasure area, and in a curve shape with a periodontal ligament. The model with a periodontal ligament showed 40% higher stress values compared to the no-ligament model. A smaller radius of curvature resulted in 20% to 40% higher stress values. The curved model increased stress values at the distal connector by 65% compared to the straight model. Support by teeth, occlusal curvature, and a small radius of curvature at the embrasure area negatively affect stress distribution patterns in the connector area of all-ceramic FPDs.

  • 36.
    Nordström, Göran
    Umeå universitet, Medicinska fakulteten, Institutionen för odontologi, Protetik. Umeå universitet, Medicinska fakulteten, Institutionen för samhällsmedicin och rehabilitering, Geriatrik.
    Oral health and dietary habits in an elderly city population: a report from the Umeå longitudinal study1995Doktoravhandling, med artikler (Annet vitenskapelig)
  • 37.
    Nyström, Elisabeth
    et al.
    Umeå universitet, Medicinsk fakultet, Odontologi, Käkkirurgi.
    Kahnberg, Karl-Erik
    Gunne, Johan
    Umeå universitet, Medicinsk fakultet, Odontologi, Protetik.
    Bone grafts and Brånemark implants in the treatment of the severely resorbed maxilla: a 2-year longitudinal study.1993Inngår i: International Journal of Oral & Maxillofacial Implants, ISSN 0882-2786, Vol. 8, nr 1, 45-53 s.Artikkel i tidsskrift (Fagfellevurdert)
    Abstract [en]

    A combination of horseshoe-shaped iliac bone grafts and Brånemark implants was used in 30 patients with severely resorbed maxillary alveolar ridges. All patients were followed clinically for 2 years and evaluated with regard to prosthesis stability, fixture survival, wound healing complications, and soft tissue conditions. Surgery was performed by the same oral surgeons using identical procedures, and the prosthetic treatment was performed by the same prosthodontist. The development group included the first 10 patients and the routine group included the following 20. Fixture survival in the development group was 54.4%, whereas 88.3% of the fixtures in the routine group have survived after 2 years. The average fixture survival in the study was 77.4%. Three patients in the development group lost all fixtures, primarily the result of trauma to the grafted region. With respect to the difficult situation many of these patients experienced, the survival rate should be considered most acceptable.

  • 38.
    Nyström, Elisabeth
    et al.
    Umeå universitet, Medicinsk fakultet, Odontologi, Käkkirurgi.
    Lundgren, Stefan
    Umeå universitet, Medicinsk fakultet, Odontologi, Käkkirurgi.
    Gunne, Johan
    Umeå universitet, Medicinsk fakultet, Odontologi, Protetik.
    Nilson, Hans
    Umeå universitet, Medicinsk fakultet, Odontologi, Protetik.
    Interpositional bone grafting and Le Fort I osteotomy for reconstruction of the atrophic edentulous maxilla. A two-stage technique.1997Inngår i: International Journal of Oral and Maxillofacial Surgery, ISSN 0901-5027, Vol. 26, nr 6, 423-427 s.Artikkel i tidsskrift (Fagfellevurdert)
    Abstract [en]

    This study presents the results from ten consecutive patients who, because of insufficient bone volume for conventional implant placement in the maxilla, were treated with an interpositional bone graft and Le Fort I osteotomy. The endosteal implants were placed six months after the osteotomy. A total of 60 screw-shaped titanium implants (Brånemark) were placed, of which three failed to integrate during the six-month healing period. No further implants were lost during the follow-up period, ranging from 15 to 39 months after placement of the implants. All patients received fixed bridges and all have continued to function efficiently.

  • 39.
    Nyström, Elisabeth
    et al.
    Umeå universitet, Medicinska fakulteten, Institutionen för odontologi, Käkkirurgi.
    Nilson, Hans
    Umeå universitet, Medicinska fakulteten, Institutionen för odontologi, Protetik.
    Gunne, Johan
    Umeå universitet, Medicinska fakulteten, Institutionen för odontologi, Protetik.
    Lundgren, Stefan
    Umeå universitet, Medicinska fakulteten, Institutionen för odontologi, Käkkirurgi.
    A 9-14 year follow-up of onlay bone grafting in the atrophic maxilla.2009Inngår i: International Journal of Oral and Maxillofacial Surgery, ISSN 0901-5027, E-ISSN 1399-0020, Vol. 38, nr 2, 111-116 s.Artikkel i tidsskrift (Fagfellevurdert)
    Abstract [en]

    Treatment of the atrophic edentulous maxilla is challenging especially when bone graft procedures are necessary. In this study an onlay bone graft, a saddle or veneer, with or without maxillary sinus floor inlay graft, harvested from the anterior iliac crest, in combination with implants was used in the reconstruction of patients with extreme atrophy in their maxillae. The aim was to investigate treatment outcome, and the impact of gender and smoking, in 44 patients in a prospective, long-term, follow-up study concerning implant survival rate and marginal bone loss adjacent to the surfaces of the implant. Mean follow-up time was 11 years. Of 334 inserted Brånemark implants, with machined surface, 27 failed. Estimated implant survival rate was 90%. Marginal bone loss was 1.8 mm 1 year after implant surgery; 2.3 mm after 5 years; and 2.4 mm after 10 years. There was a significant difference between genders in implant survival. Marginal bone loss differed significantly between smokers and non-smokers up to the 5-year examination and between genders after the 4-year examination. The onlay bone graft, with or without a maxillary inlay graft, results in high implant survival rate, good oral function and stabilised marginal bone. All patients are still wearing their original fixed bridges.

  • 40.
    Nyström, Elisabeth
    et al.
    Umeå universitet, Medicinska fakulteten, Institutionen för odontologi, Käkkirurgi.
    Nilson, Hans
    Umeå universitet, Medicinska fakulteten, Institutionen för odontologi, Protetik.
    Gunne, Johan
    Umeå universitet, Medicinska fakulteten, Institutionen för odontologi, Protetik.
    Lundgren, Stefan
    Umeå universitet, Medicinska fakulteten, Institutionen för odontologi, Käkkirurgi.
    Reconstruction of the atrophic maxilla with interpositional bone grafting/Le Fort I osteotomy and endosteal implants: A 11-16 year follow-up.2009Inngår i: International Journal of Oral and Maxillofacial Surgery, ISSN 0901-5027, E-ISSN 1399-0020, Vol. 38, nr 1, 1-6 s.Artikkel i tidsskrift (Fagfellevurdert)
    Abstract [en]

    A Le Fort I osteotomy and interpositional bone graft in combination with implants was used in the reconstruction of patients with extreme atrophy in their maxillae. Surgery was performed in a two-stage procedure. The patients in this study had conditions with reversed intermaxillary relationships with or without increased vertical intermaxillary distance. The aim of the study was to investigate treatment outcome for patients in a prospective, long-term, follow-up with a mean of 13 years (range 11-16 years), concerning implant survival rate and marginal bone loss adjacent to the surfaces of the implant. The impact of gender and smoking was also investigated. Twenty-six patients were included in the study. Of 167 implants, 24 failed. The implant estimated survival rate was 85% at the end of the follow-up. There was no significant difference between smokers and non-smokers or genders concerning implant survival. Marginal bone loss was 2.5, 2.9, 3.0 and 3.1mm from the implant-abutment junction, after 1, 2, 5 and 10 years, respectively. The bone level stabilised after 2 years. This technique results in good facial morphology, good oral function and aesthetics. All patients are still wearing their original fixed bridges.

  • 41.
    Sjögren, G
    et al.
    Umeå universitet, Medicinsk fakultet, Odontologi, Odont materialvetenskap.
    Bergman, M
    Molin, M
    Umeå universitet, Medicinsk fakultet, Odontologi, Protetik.
    Bessing, C
    A clinical examination of ceramic (Cerec) inlays.1992Inngår i: Acta Odontologica Scandinavica, ISSN 0001-6357, Vol. 50, nr 3, 171-8 s.Artikkel i tidsskrift (Fagfellevurdert)
    Abstract [en]

    Two hundred and five Cerec ceramic inlays placed by 8 dentists in 72 patients were examined independently by 3 calibrated evaluators 12-24 months after insertion, using the criteria of the California Dental Association (CDA) and also certain periodontal variables. Proximal dental plaque and bleeding on probing were not seen more often on Cerec surfaces than on control homologous surfaces. Ten patients reported postoperative sensitivity after treatment with Cerec inlays. Excellent CDA ratings for Color and Surface were obtained in 57% and 26%, respectively, and for Anatomic Form and Margin Integrity in 55% and 83%, respectively. Obvious differences were seen among the participating dentists with regard to the clinical quality of Cerec inlays. At present, the long-term performance of the Cerec technique cannot be predicted.

  • 42. Sjögren, G
    et al.
    Molin, M
    Umeå universitet, Medicinsk fakultet, Odontologi, Protetik.
    van Dijken, J
    Bergman, M
    Ceramic inlays (Cerec) cemented with either a dual-cured or a chemically cured composite resin luting agent. A 2-year clinical study.1995Inngår i: Acta Odontologica Scandinavica, ISSN 0001-6357, Vol. 53, nr 5, 325-30 s.Artikkel i tidsskrift (Fagfellevurdert)
    Abstract [en]

    On the basis of the criteria of the California Dental Association (CDA), 66 CAD/CAM-manufactured ceramic class-II inlays (Cerec) were compared intraindividually after they had been cemented with either a chemically cured or a dual-cured composite resin luting agent in 27 patients. Plaque and gingival conditions, the overall time consumption for producing each inlay, and the frequency of postoperative sensitivity were also evaluated. There was no statistically significant difference between the two luting agents with regard to the properties evaluated. One inlay was replaced owing to fracture of the restored tooth just before the 24-month re-examination. After 2 years excellent CDA ratings were obtained for color in 92% of the remaining 65 inlays. The corresponding figures for surface and for anatomic form were 100% and 85%, respectively. For margin integrity 85% of the 33 inlays cemented with the dual-cured luting agent and 88% of the 33 inlays cemented with the chemically cured luting agent were rated excellent after 2 years.

  • 43. Sjögren, G
    et al.
    Molin, M
    Umeå universitet, Medicinsk fakultet, Odontologi, Protetik.
    van Dijken, J W
    A 5-year clinical evaluation of ceramic inlays (Cerec) cemented with a dual-cured or chemically cured resin composite luting agent.1998Inngår i: Acta Odontologica Scandinavica, ISSN 0001-6357, Vol. 56, nr 5, 263-7 s.Artikkel i tidsskrift (Fagfellevurdert)
    Abstract [en]

    Sixty-six class-II CAD/CAM-manufactured ceramic inlays (Cerec) were placed in 27 patients. Each patient received at least one inlay luted with a dual-cured resin composite and one inlay luted with a chemically cured resin composite. The inlays were examined 5 years after luting using the California Dental Association (CDA) criteria. Eighty-nine percent of the 66 inlays were rated 'satisfactory'. During the follow-up period replacement was required for 3 inlays because of inlay fractures (4.5%) and 1 inlay because of fracture of the tooth substance (1.5%). All those inlays were luted with the dual-cured resin composite luting agent. Of the remaining 62 inlays the CDA rating 'excellent' was given to 84% for color, 97% for surface, and 81% for anatomic form. 'Excellent' margin integrity was seen in 52% of the dual-cured resin composite luted inlays and in 61% of the chemically cured resin composite luted inlays. No statistically significant (P> 0.05) difference was observed between the two luting agents.

  • 44.
    Sjöström, Mats
    et al.
    Umeå universitet, Medicinska fakulteten, Institutionen för odontologi, Käkkirurgi.
    Lundgren, Stefan
    Umeå universitet, Medicinska fakulteten, Institutionen för odontologi, Käkkirurgi.
    Nilson, Hans
    Umeå universitet, Medicinska fakulteten, Institutionen för odontologi, Protetik.
    Sennerby, Lars
    Umeå universitet, Medicinska fakulteten, Institutionen för odontologi, Käkkirurgi.
    Monitoring of implant stability in grafted bone using resonance frequency analysis: A clinical study from implant placement to 6 months of loading.2005Inngår i: International Journal of Oral and Maxillofacial Surgery, ISSN 0901-5027, E-ISSN 1399-0020, Vol. 34, nr 1, 45-51 s.Artikkel i tidsskrift (Fagfellevurdert)
    Abstract [en]

    The aim of this prospective study was to compare implants placed in grafted and normal non-grafted maxilla by means of resonance frequency analysis (RFA), clinical stability and implant failure. Twenty-nine patients with severe atrophy of the edentulous maxilla were treated with autogenous bone grafts as onlay (24 patients) or as interpositional grafts in conjunction with a Le Fort I osteotomy (five patients) 6 months prior to placement of 222 implants. Ten non-grafted patients treated with 75 Brånemark implants in the edentulous maxillae served as a control group. RFA was performed at implant placement, abutment connection and after 6 months of bridge loading. Seventeen (8%) implants were lost in the grafted bone and one (1%) in normal bone. RFA revealed a similar pattern in both grafted and normal maxillae, i.e. increasing resonance frequency (RF) with time (Wilcoxon Signed Rank test for paired data). Twenty implants that were rotation mobile (low primary stability) at the time of insertion showed a significantly lower value at implant placement according to RFA (Mann-Whitney U-test, P = 0.020). The RF for the failed implants revealed a tendency towards lower values (Mann-Whitney U-test, P = 0.072), compared to the successful implants. It is concluded that implants placed in grafted bone when using a two-stage technique achieve a stability similar to that of implants placed in normal non-grafted bone.

  • 45.
    Sjöström, Mats
    et al.
    Umeå universitet, Medicinska fakulteten, Institutionen för odontologi, Käkkirurgi.
    Sennerby, Lars
    Umeå universitet, Medicinska fakulteten, Institutionen för odontologi, Käkkirurgi.
    Nilson, Hans
    Umeå universitet, Medicinska fakulteten, Institutionen för odontologi, Protetik.
    Lundgren, Stefan
    Umeå universitet, Medicinska fakulteten, Institutionen för odontologi, Käkkirurgi.
    Reconstruction of the atrophic edentulous maxilla with free iliac crest grafts and implants: a 3-year report of a prospective clinical study.2007Inngår i: Clinical Implant Dentistry and Related Research, ISSN 1523-0899, E-ISSN 1708-8208, Vol. 9, nr 1, 46-59 s.Artikkel i tidsskrift (Fagfellevurdert)
    Abstract [en]

    PURPOSE: The purpose of this study was to perform a longitudinal follow-up study of implant stability in grafted maxillae with the aid of clinical, radiological, and resonance frequency analysis (RFA) parameters. MATERIALS AND METHODS: The atrophic edentulous maxillae in 29 patients were reconstructed with free iliac crest grafts using onlay/inlay or interpositional grafting techniques. The endpoint of the resorption pattern in the maxilla determined the grafting technique used. Endosteal implants were placed after 6 months of bone-graft healing. Implant stability was measured four times using RFA: when the implants were placed, after 6 to 8 months of healing, after 6 months and 3 years of bridge loading. Individual checkups were performed at the two later RFA registrations after removal of the supraconstructions (Procera Implant Bridge, Nobel Biocare AB, Goteborg, Sweden). Radiological follow up of marginal bone level was performed annually. RESULTS: Twenty-five patients remained for the follow-up period. A total of 192 implants were placed and with a survival rate of 90% at the 3-year follow up. Women and an implant position with a class 6 resorption prior to reconstruction were factors with significant increased risk for implant failure (multivariate logistic regression). Twelve of the 20 failed implants were lost before loading (early failures). The change in the marginal bone level was 0.3 +/- 0.3 mm between baseline (bridge delivery) and the 3-year follow up. The implant stability quotient (ISQ) value for all implants differed significantly between abutment connection (60.2 +/- 7.3) and after 6 months of bridge loading (62.5 +/- 5.5) (Wilcoxon signed ranks test for paired data, p=.05) but were nonsignificant between 6 months of bridge loading and 3 years of bridge loading (61.8 +/- 5.5). There was a significant difference between successful and failed implants when the ISQ values were compared for individual implants at placement (Mann-Whitney U test, p=.004). All 25 patients were provided with fixed implant bridges at the time of the 3-year follow up. CONCLUSION: This clinical follow up using radiological examinations and RFA measurements indicates a predictable and stable long-term result for patients with atrophic edentulous maxillae reconstructed with autogenous bone and with delayed placement of endosteal implants. The ISQ value at the time of placement can probably serve as an indicator of level of risk for implant failure.

  • 46.
    Sulniute, Rima
    et al.
    Umeå universitet, Medicinska fakulteten, Institutionen för medicinsk kemi och biofysik.
    Lindh, Tomas
    Umeå universitet, Medicinska fakulteten, Institutionen för odontologi, Protetik. Umeå universitet, Medicinska fakulteten, Institutionen för medicinsk kemi och biofysik.
    Wilczynska, Malgorzata
    Umeå universitet, Medicinska fakulteten, Institutionen för medicinsk kemi och biofysik.
    Li, Jinan
    Umeå universitet, Medicinska fakulteten, Institutionen för medicinsk kemi och biofysik.
    Ny, Tor
    Umeå universitet, Medicinska fakulteten, Institutionen för medicinsk kemi och biofysik.
    Plasmin is essential in preventing periodontitis in mice2011Inngår i: American Journal of Pathology, ISSN 0002-9440, E-ISSN 1525-2191, Vol. 179, nr 2, 819-828 s.Artikkel i tidsskrift (Fagfellevurdert)
    Abstract [en]

    Periodontitis involves bacterial infection, inflammation of the periodontium, degradation of gum tissue, and alveolar bone resorption, which eventually leads to loss of teeth. To study the role of the broad-spectrum protease plasmin in periodontitis, we examined the oral health of plasminogen (Plg)-deficient mice. In wild-type mice, the periodontium was unaffected at all time points studied; in Plg-deficient mice, periodontitis progressed rapidly, within 20 weeks. Morphological study results of Plg-deficient mice revealed detachment of gingival tissue, resorption of the cementum layer, formation of necrotic tissue, and severe alveolar bone degradation. IHC staining showed massive infiltration of neutrophils in the periodontal tissues. Interestingly, doubly deficient mice, lacking both tissue- and urokinase-type plasminogen activators, developed periodontal disease similar to that in Pig-deficient mice; however, mice lacking only tissue- or urokinase-type plasminogen activator remained healthy. Supplementation by injection of Pig-deficient mice with human plasminogen for 10 days led to necrotic tissue absorption, inflammation subsidence, and full regeneration of gum tissues. Notably, there was also partial regrowth of degraded alveolar bone. Taken together, our results show that plasminogen is essential for the maintenance of a healthy periodontium and plays an important role in combating the spontaneous development of chronic periodontitis. Moreover, reversal to healthy status after supplementation of Pig-deficient mice with plasminogen suggests the possibility of using plasminogen for therapy of periodontal diseases. (Am J Pathol 2011, 179:819-828; DOI: 10.1016/j.ajpath.2011.05.003)

  • 47.
    Sundh, Anders
    et al.
    Umeå universitet, Medicinska fakulteten, Institutionen för odontologi.
    Molin, Margareta
    Umeå universitet, Medicinska fakulteten, Institutionen för odontologi, Protetik.
    Sjögren, Göran
    Umeå universitet, Medicinska fakulteten, Institutionen för odontologi, Odontologisk materialvetenskap.
    Fracture resistance of yttrium oxide partially-stabilized zirconia all-ceramic bridges after veneering and mechanical fatigue testing2005Inngår i: Dental Materials, ISSN 0109-5641, E-ISSN 1879-0097, Vol. 21, nr 5, 476-482 s.Artikkel i tidsskrift (Fagfellevurdert)
    Abstract [en]

    OBJECTIVES: Yttria-stabilized zirconia (Y-TZP) ceramic is a high-performance material with excellent mechanical properties suitable for fixed partial dentures. The purpose of this study was to evaluate after fatigue testing, the effect of heat-treatment and veneering on the fracture resistance of frameworks manufactured using sintered and subsequently hot isostatic pressed yttrium oxide partially-stabilized zirconia (Denzir).

    METHODS: The specimens were subjected to dynamic loading in water. Thereafter, using a universal testing machine, the fracture resistance of three-unit fixed partial dentures was determined; (i) of the frameworks as delivered after machining, (ii) after the frameworks had been subjected to heat-treatment similar to veneering with a glass-ceramic (Eris) or a feldspar-based ceramic (Vita D) and (iii) after the frameworks had been veneered with these ceramics. In addition, the fracture resistance of frameworks as delivered after machining not subjected to dynamic loading in water was determined.

    RESULTS: Cyclic loading in water did not significantly (p>0.05) affect the fracture resistance. The load necessary to fracture the frameworks as delivered after machining was significantly (p<0.001) higher than for the heat-treated and veneered specimens. No significant difference was seen between the specimens veneered with Eris and those veneered with Vita D (p>0.05). For all but three specimens the fractures were located in the loading point and through one of the connectors.

    SIGNIFICANCE: Heat-treatment and veneering reduce fracture resistance of hot isostatic pressed zirconia. Nevertheless, the results obtained indicate that it is an interesting material for potential in all-ceramic restorations.

  • 48.
    Tidehag, Per
    Umeå universitet, Medicinska fakulteten, Institutionen för odontologi, Protetik. Umeå universitet, Medicinska fakulteten, Institutionen för folkhälsa och klinisk medicin, Näringsforskning.
    Iron absorption and iron status related to diet: an experimental and epidemiological study1995Doktoravhandling, med artikler (Annet vitenskapelig)
    Abstract [en]

    The absorption of iron from the diet is a major determinant of the iron status of an individual. Accurate measures of iron absorption are thus essential in the determination of the effects of diet composition on iron absorption and status.

    The aim of these studies have firstly been to investigate different methods to measure iron absorption and effects of diet in both rats and humans. Secondly to describe variations in iron status in a general population and to relate the variations to diet.

    Experimental studies in rats: The most important factors determining the availability of iron from the diet to growing rats appears to be the concentration of iron in the diet and the iron status of the rats. The type of cereal |rain in the diet and the diet phytate and fiber concentrations were of far less importance. The absorption of Fe from test meals, the iron balance over a period of a few days and the blood hemoglobin and serum and liver iron concentrations were in good general agreement on the effects of diet and iron status on the bioavailability of iron from grain diets. The extent of coprophagy in rats is not affected by diet or iron status and did not affect iron absorption appreciably.

    Effect of dairy products on iron absorption in man: The effect of milk and fermented milk on iron absorption was studied in nine ileostomy subjects. We found no decrease in iron absorption during two three-week periods on a high calcium (milk) diet. The results of the present study differ from those studies in which the absorption of radioiron from test meals was measured, which have shown a pronounced effect of high calcium levels. We believe that these differences in results were caused by differences in experimental design and choice of measurement method. Our results support earlier findings that the iron status of the subject rather than the bioavailability of dietary iron is the major factor determining absorption of dietary non-heme iron.

    Measurement of iron absorption from single meals and daily diets in humans using radioiron: Ten ileostomy subjects were given the same composite diet for all three meals each day for five consecutive days (meal proportion ratio 1:2:4 for breakfast, lunch and dinner respectively). The iron absorption from a low-fiber diet measured from the morning meals (55Fe) was almost 80% higher than the average iron absorption measured from all meals (59Fe) during the last two days on this diet. The iron absorption from a high fiber diet eaten at breakfast was almost 50% higher than the daily average absorption. This suggests that all meals of the day should be labeled with radioiron and not just the morning meal.

    Population studies of diet and iron status: In a randomly selected population in Northern Sweden lower iron status was associated with a high intake of dairy products in women (25-44 yr.). The striking result was however that iron status was not related to other major variations in dietary intake, particularly intake of energy and iron. No correlation could be demonstrated between iron status measured as ferritin, serum iron or TIBC and the estimated intakes of calcium, fiber, ascorbic acid, meat, tea or coffee, all of which are known to be factors which influence the bioavailability of iron. On the population level, factors other than diet, e.g. menstruation and metabolic factors, were more important than diet as determinants of iron status.

  • 49. Åstrand, Per
    et al.
    Ahlqvist, Jan
    Umeå universitet, Medicinska fakulteten, Institutionen för odontologi, Oral diagnostisk radiologi.
    Gunne, Johan
    Umeå universitet, Medicinska fakulteten, Institutionen för odontologi, Protetik.
    Nilsson, Hans
    Umeå universitet, Medicinska fakulteten, Institutionen för odontologi, Protetik.
    Implant treatment of patients with edentulous jaws: a 20-year follow-up2008Inngår i: Clinical Implant Dentistry and Related Research, ISSN 1523-0899, E-ISSN 1708-8208, Vol. 10, nr 4, 207-217 s.Artikkel i tidsskrift (Fagfellevurdert)
    Abstract [en]

    BACKGROUND: Implant-supported prostheses are today often used in rehabilitation of partially or totally edentulous patients. Both patients and the dental profession often regard implant treatment as successful in a life perspective. Therefore, studies with a long-term follow-up are important.

    PURPOSE: The aim was to investigate the outcome of implant treatment with fixed prostheses in edentulous jaws after 20 years, with special reference to survival rate of implants and prostheses and frequency of peri-implantitis.

    MATERIALS AND METHODS: The patient material was a group of patients treated in the early 1980s. The original patient group comprised the first 48 consecutive patients treated with implant-supported prostheses at Umeå University. All patients were edentulous in one or two jaws. The patients had a mean age at the implant insertion of 54.3 years (range 40-74). At the planning of this study 20 years after treatment, 19 of the 48 patients were found to be deceased. Of the 29 patients still alive, 21 patients with altogether 23 implant-supported prostheses could be examined clinically and radiographically. All patients were treated ad modum Brånemark (Nobel Biocare AB, Göteborg, Sweden) with a two-stage surgical procedure. The implants had a turned surface. Abutment connections were performed 3 to 4 months after fixture insertion in the mandible, and after a minimum of 6 months in the maxilla. The prostheses were fabricated with a framework of gold alloy and acrylic artificial teeth.

    RESULTS: The 21 patients (with 23 implant prostheses) examined had at the time of treatment got 123 implants (27 in the upper jaw and 96 in the lower jaw) inserted. Only one of these implants had been lost (about 2 years after loading) giving a survival rate of 99.2%. Very small changes occurred in the marginal bone level. Between the 1 and 20-year examinations, the mean bone loss was 0.53 mm and the mean bone level at the final examination was 2.33 mm below the reference point.

    CONCLUSIONS: This follow-up over two decades of implant-supported prostheses demonstrates a very good prognosis for the treatment performed. The frequencies of peri-implantitis, implant failures, or other complications were very small, and the original treatment concept with a two-stage surgery and a turned surface of the implants will obviously give very good results.

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