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Lewis, C. A., Jackson, J. A., Stjernbrandt, A., Andersson, G., Mukka, S., Wahlström, J. & Liv, P. (2025). Occupational risk factors for thumb carpometacarpal joint osteoarthritis: a register-based study of construction workers. Occupational and Environmental Medicine
Åpne denne publikasjonen i ny fane eller vindu >>Occupational risk factors for thumb carpometacarpal joint osteoarthritis: a register-based study of construction workers
Vise andre…
2025 (engelsk)Inngår i: Occupational and Environmental Medicine, ISSN 1351-0711, E-ISSN 1470-7926Artikkel i tidsskrift (Fagfellevurdert) Epub ahead of print
Abstract [en]

OBJECTIVES: The study investigated the association between occupational biomechanical risk factors and the occurrence of thumb carpometacarpal joint osteoarthritis (CMC1 OA) in construction workers.

METHODS: Male construction workers (n=237 525), participating in a Swedish occupational surveillance programme between 1971 and 1993, were followed between 1997 and 2019. CMC1 OA diagnoses were identified through linkage with national medical registries. Job title, smoking status, height, weight and age were collected from the surveillance programme. A job exposure matrix (JEM) was developed with exposure estimates on biomechanical risk factors for each occupational group. Relative risk (RR) of CMC1 OA diagnosis was calculated using a Poisson regression model.

RESULTS: There was an increased risk of CMC1 OA for all biomechanical risk factors (RR range 1.3-1.5). Exposure-response patterns were seen for repetitive wrist flexion and extension (low: RR 1.30 (95% CI 1.07 to 1.59), moderate: 1.32 (95% CI 1.07 to 1.62), high: 1.45 (95% CI 1.19 to 1.75)), wrist extension (low: 1.31 (95% CI 1.09 to 1.59), moderate: 1.41 (95% CI 1.17 to 1.70) and heavy lifting (low: 1.13 (95% CI 0.92 to 1.38), moderate: 1.45 (95% CI 1.18 to 1.77), high: 1.50 (95% CI 1.24 to 1.82). Electricians (1.29 (95% CI 1.03 to 1.89)), concrete workers (1.31 (95% CI 1.02 to 1.67)), plumbers (1.37 (95% CI 1.07 to 1.76)), sheet-metal workers (1.58 (95% CI 1.18 to 2.10)), wood workers (1.66 (95% CI 1.36 to 2.03)), repairers (1.75 (95% CI 1.06 to 2.90)) and glass workers (2.21 (95% CI 1.42 to 3.44) had an increased risk of CMC1 OA compared with the reference group.

CONCLUSION: Wrist movements and hand loading were associated with CMC1 OA.

sted, utgiver, år, opplag, sider
BMJ Publishing Group Ltd, 2025
Emneord
Ergonomics, Occupational Health, Osteoarthritis, Vibration, Workload
HSV kategori
Identifikatorer
urn:nbn:se:umu:diva-235337 (URN)10.1136/oemed-2024-109949 (DOI)39904624 (PubMedID)
Forskningsfinansiär
Forte, Swedish Research Council for Health, Working Life and Welfare, 2016-01016
Tilgjengelig fra: 2025-02-12 Laget: 2025-02-12 Sist oppdatert: 2025-02-13
Lundmark, R., Agrell, A., Simonsen Abildgaard, J., Wahlström, J. & Tafvelin, S. (2024). A joint training of healthcare line managers and health and safety representatives in facilitating occupational health interventions: a feasibility study protocol for the co-pilot project. Frontiers in Psychology, 15, Article ID 1340279.
Åpne denne publikasjonen i ny fane eller vindu >>A joint training of healthcare line managers and health and safety representatives in facilitating occupational health interventions: a feasibility study protocol for the co-pilot project
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2024 (engelsk)Inngår i: Frontiers in Psychology, E-ISSN 1664-1078, Vol. 15, artikkel-id 1340279Artikkel i tidsskrift (Fagfellevurdert) Published
Abstract [en]

Healthcare employees are experiencing poor wellbeing at an increasing rate. The healthcare workforce is exposed to challenging tasks and a high work pace, a situation that worsened during and after the COVID-19 pandemic. In turn, exposure to these high demands contributes to poor health, increased turnover, reduced job satisfaction, reduced efficacy, and reduced patient satisfaction and safety. Therefore, it is imperative that we identify measures to mitigate this crisis. One piece of this puzzle is how to implement sustainable tools and processes to improve the work environment of healthcare organizations. In this paper, we present the study protocol for the outlining and piloting of a joint training for pairs of healthcare line managers and their associated health and safety representatives in a Swedish healthcare organization. The objective of the training is to aid and advance the implementation of interventions to improve the work environment at the unit level. Following recommendations in the literature, the training is based on a stepwise approach that considers the specific context and focuses on the involvement of employees in creating interventions based on their needs. A central component of the training is the development of the pairs’ collaboration in prioritizing, developing, implementing, and evaluating the interventions. The training is based on an on-the-job train-the-trainer approach in which participants are progressively trained during four workshops in the steps of a participatory intervention process. Between these workshops, the pairs follow the same progressive steps together with their employees to develop and implement interventions at their unit. The pilot will involve four pairs (i.e., eight participants) representing different parts and functions of the organization and will be conducted over a period of three months. We will use a mixed method design to evaluate preconditions, the process, and proximal transfer and implementation outcome factors of the training. The overall aim of the pilot is to appraise its feasibility and be able to adjust the training before a potential scale-up.

sted, utgiver, år, opplag, sider
Frontiers Media S.A., 2024
Emneord
intervention, pilot study, study protocol, health care, participatory, on-job, line managers, health and safety representatives
HSV kategori
Identifikatorer
urn:nbn:se:umu:diva-225125 (URN)10.3389/fpsyg.2024.1340279 (DOI)001243931200001 ()38860038 (PubMedID)2-s2.0-85195360385 (Scopus ID)
Tilgjengelig fra: 2024-05-28 Laget: 2024-05-28 Sist oppdatert: 2024-07-02bibliografisk kontrollert
Sun, M., da Silva, M., Bjørge, T., Fritz, J., Mboya, I. B., Jerkeman, M., . . . Stocks, T. (2024). Body mass index and risk of over 100 cancer forms and subtypes in 4.1 million individuals in Sweden: the obesity and disease development Sweden (ODDS) pooled cohort study. The Lancet Regional Health: Europe, 45, Article ID 101034.
Åpne denne publikasjonen i ny fane eller vindu >>Body mass index and risk of over 100 cancer forms and subtypes in 4.1 million individuals in Sweden: the obesity and disease development Sweden (ODDS) pooled cohort study
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2024 (engelsk)Inngår i: The Lancet Regional Health: Europe, E-ISSN 2666-7762, Vol. 45, artikkel-id 101034Artikkel i tidsskrift (Fagfellevurdert) Published
Abstract [en]

Background: Obesity, assessed by body mass index (BMI), is an established risk factor for 13 cancers. We aimed to identify further potential obesity-related cancers and to quantify their association with BMI relative to that of established obesity-related cancers.

Methods: Using Cox regression models on 4,142,349 individuals in Sweden (mean age 27.1 years at weight measurement), we calculated hazard ratios (HRs) for the association between BMI and the risk of 122 cancers and cancer subtypes, grouped by topography and morphology. Cancers with a positive association (i.e., HR >1) at an α-level of 0.05 for obesity (BMI ≥30 kg/m2) vs. normal weight (BMI 18.5–24.9 kg/m2) or per 5 kg/m2 higher BMI, for which obesity is not an established risk factor, were considered potentially obesity related.

Findings: After 100.2 million person-years of follow-up, 332,501 incident cancer cases were recorded. We identified 15 cancers in men and 16 in women as potentially obesity related. These were cancers of the head and neck, gastrointestinal tract, malignant melanoma, genital organs, endocrine organs, connective tissue, and haematological malignancies. Among these, there was evidence of differential associations with BMI between subtypes of gastric cancer, small intestine cancer, cervical cancer, and lymphoid neoplasms (P values for heterogeneity in HRs <0.05). The HR (95% confidence interval) per 5 kg/m2 higher BMI was 1.17 (1.15–1.20) in men and 1.13 (1.11–1.15) in women for potential obesity-related cancers (51,690 cases), and 1.24 (1.22–1.26) in men and 1.12 (1.11–1.13) in women for established obesity-related cancers (84,384 cases). Interpretation: This study suggests a large number of potential obesity-related cancers could be added to already established ones. Importantly, the magnitudes of the associations were largely comparable to those of the already established obesity-related cancers. We also provide evidence of specific cancer subtypes driving some associations with BMI. Studies accounting for cancer-specific confounders are needed to confirm these findings.

sted, utgiver, år, opplag, sider
Elsevier, 2024
Emneord
Body mass index, Cancer, Obesity
HSV kategori
Identifikatorer
urn:nbn:se:umu:diva-228809 (URN)10.1016/j.lanepe.2024.101034 (DOI)2-s2.0-85201383782 (Scopus ID)
Prosjekter
ODDSMONICASIMPLERSwedish Twin RegistryWICTORY
Forskningsfinansiär
Swedish Research Council, 2017-00650Swedish Research Council, 2017-00644Swedish Research Council, 2021-00160Swedish Research Council, 2021-00180Lund University, STYR 2019/2046).
Tilgjengelig fra: 2024-08-28 Laget: 2024-08-28 Sist oppdatert: 2024-08-28bibliografisk kontrollert
Lindegård, A., Grimby-Ekman, A., Wahlström, J. & Gustafsson, E. (2024). Can biofeedback training in combination with ergonomic information reduce pain among young adult computer users with neck and upper extremity symptoms?: A randomized controlled intervention study. Applied Ergonomics, 114, Article ID 104155.
Åpne denne publikasjonen i ny fane eller vindu >>Can biofeedback training in combination with ergonomic information reduce pain among young adult computer users with neck and upper extremity symptoms?: A randomized controlled intervention study
2024 (engelsk)Inngår i: Applied Ergonomics, ISSN 0003-6870, E-ISSN 1872-9126, Vol. 114, artikkel-id 104155Artikkel i tidsskrift (Fagfellevurdert) Published
Abstract [en]

The aim of this randomized controlled study was to explore if an intervention with biofeedback training in combination with ergonomic discussions, could improve working technique and work postures, and reduce pain intensity and perceived exertion in young adult computer users with ongoing neck and upper extremity symptoms. 39 participants were divided into an intervention group and a control group. The intervention consisted of 4 sessions during a three-month period. Working technique, working postures, rated perceived exertion, pain intensity, and duration of computer use were measured at baseline and follow ups after 6 and 12 months. The intervention did not significantly improve working technique and working postures, nor reduce pain intensity and perceived exertion in the intervention group compared to the control group. However, there was a statistically significant reduction in reported pain intensity in the neck/shoulder for the whole group. Also, there was a trend that time spent with computer work without breaks was more reduced in the intervention group than in the control group.

sted, utgiver, år, opplag, sider
Elsevier, 2024
Emneord
Musculoskeletal disorders, Perceived exertion, Working technique
HSV kategori
Identifikatorer
urn:nbn:se:umu:diva-215932 (URN)10.1016/j.apergo.2023.104155 (DOI)2-s2.0-85174540298 (Scopus ID)
Forskningsfinansiär
Forte, Swedish Research Council for Health, Working Life and Welfare
Tilgjengelig fra: 2023-11-02 Laget: 2023-11-02 Sist oppdatert: 2025-02-11bibliografisk kontrollert
da Silva, M., Fritz, J., Mboya, I. B., Sun, M., Wahlström, J., van Guelpen, B., . . . Stocks, T. (2024). Cohort profile: the Obesity and Disease Development Sweden (ODDS) study, a pooled cohort. BMJ Open, 14(7), Article ID e084836.
Åpne denne publikasjonen i ny fane eller vindu >>Cohort profile: the Obesity and Disease Development Sweden (ODDS) study, a pooled cohort
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2024 (engelsk)Inngår i: BMJ Open, E-ISSN 2044-6055, Vol. 14, nr 7, artikkel-id e084836Artikkel i tidsskrift (Fagfellevurdert) Published
Abstract [en]

PURPOSE: The Obesity and Disease Development Sweden (ODDS) study was designed to create a large cohort to study body mass index (BMI), waist circumference (WC) and changes in weight and WC, in relation to morbidity and mortality.

PARTICIPANTS: ODDS includes 4 295 859 individuals, 2 165 048 men and 2 130 811 women, in Swedish cohorts and national registers with information on weight assessed once (2 555 098 individuals) or more (1 740 761 individuals), in total constituting 7 733 901 weight assessments at the age of 17-103 years in 1963-2020 (recalled weight as of 1911). Information on WC is available in 152 089 men and 212 658 women, out of whom 108 795 have repeated information on WC (in total 512 273 assessments). Information on morbidity and mortality was retrieved from national registers, with follow-up until the end of 2019-2021, varying between the registers.

FINDINGS TO DATE: Among all weight assessments (of which 85% are objectively measured), the median year, age and BMI (IQR) is 1985 (1977-1994) in men and 2001 (1991-2010) in women, age 19 (18-40) years in men and 30 (26-36) years in women and BMI 22.9 (20.9-25.4) kg/m2 in men and 23.2 (21.2-26.1) kg/m2 in women. Normal weight (BMI 18.5-24.9 kg/m2) is present in 67% of assessments in men and 64% in women and obesity (BMI≥30 kg/m2) in 5% of assessments in men and 10% in women. The median (IQR) follow-up time from the first objectively measured or self-reported current weight assessment until emigration, death or end of follow-up is 31.4 (21.8-40.8) years in men and 19.6 (9.3-29.0) years in women. During follow-up, 283 244 men and 123 457 women died.

FUTURE PLANS: The large sample size and long follow-up of the ODDS Study will provide robust results on anthropometric measures in relation to risk of common diseases and causes of deaths, and novel findings in subgroups and rarer outcomes.

sted, utgiver, år, opplag, sider
BMJ Publishing Group Ltd, 2024
Emneord
Body Mass Index, EPIDEMIOLOGY, Obesity, Weight Gain
HSV kategori
Identifikatorer
urn:nbn:se:umu:diva-228073 (URN)10.1136/bmjopen-2024-084836 (DOI)001306358600001 ()39013647 (PubMedID)2-s2.0-85199015805 (Scopus ID)
Forskningsfinansiär
Swedish Research Council, 2021-01934Swedish Cancer Society, 230633 SIAMrs. Berta Kamprad's Cancer Foundation, FBKS-2021-12-343The Crafoord Foundation, 20210628 20220572 20230547Swedish Cancer Society, 232767 Pj
Tilgjengelig fra: 2024-07-31 Laget: 2024-07-31 Sist oppdatert: 2024-10-30bibliografisk kontrollert
Stjernbrandt, A., Pettersson, H., Wahlström, J., Rödin, I., Nilsson, T. & Burström, L. (2024). Hand cold stress testing among Arctic open-pit miners: a clinical study. International Journal of Occupational Safety and Ergonomics
Åpne denne publikasjonen i ny fane eller vindu >>Hand cold stress testing among Arctic open-pit miners: a clinical study
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2024 (engelsk)Inngår i: International Journal of Occupational Safety and Ergonomics, ISSN 1080-3548, E-ISSN 2376-9130Artikkel i tidsskrift (Fagfellevurdert) Epub ahead of print
Abstract [en]

Objectives: This study aimed to evaluate the influence of individual characteristics (sex, age, body mass index [BMI] and smoking habits) on the tolerance time, pain ratings and rewarming time of hand cold stress testing (CST).

Methods: We included 153 subjects (63% men) working in a Swedish open-pit mine (participation rate 41%). The right hand was immersed in 3 °C circulating water for up to 45 s. Pain ratings were registered every fifth second using a visual analog scale.

Results: The tolerance time (mean ± standard deviation) was 35 ± 12 s for men and 29 ± 14 s for women (p = 0.007). The youngest age group (18–29 years) had the longest tolerance time, while the oldest group (54–65 years) had the shortest (p = 0.005). Women had significantly higher pain ratings than men after 5, 10 and 25 s. The group with the highest BMI had the shortest rewarming time (p < 0.001).

Conclusions: Age and sex influenced the tolerance time of hand CST, while only sex affected the pain ratings and BMI the rewarming time. When performing CST in future studies, these parameters should be considered.

sted, utgiver, år, opplag, sider
Taylor & Francis, 2024
Emneord
cold climate, cold sensitivity, cold stress testing, mining, peripheral nervous system diseases, Raynaud disease, Sweden, vibration
HSV kategori
Identifikatorer
urn:nbn:se:umu:diva-229050 (URN)10.1080/10803548.2024.2383051 (DOI)39185579 (PubMedID)2-s2.0-85202042649 (Scopus ID)
Forskningsfinansiär
Forte, Swedish Research Council for Health, Working Life and Welfare, 2011-0494Region Västerbotten, 967266Region Västerbotten, 979090
Tilgjengelig fra: 2024-09-03 Laget: 2024-09-03 Sist oppdatert: 2024-09-03
Stjernbrandt, A., Pettersson, H., Vihlborg, P., Wahlström, J. & Lewis, C. A. (2024). Occupational exposure to whole-body vibration and neck pain in the Swedish general population. Ergonomics, 67(2), 136-147
Åpne denne publikasjonen i ny fane eller vindu >>Occupational exposure to whole-body vibration and neck pain in the Swedish general population
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2024 (engelsk)Inngår i: Ergonomics, ISSN 0014-0139, E-ISSN 1366-5847, Vol. 67, nr 2, s. 136-147Artikkel i tidsskrift (Fagfellevurdert) Published
Abstract [en]

The primary aim of this study was to determine if occupational exposure to whole-body vibration (WBV) was associated with reporting neck pain. A cross-sectional study was conducted on a sample of the general population living in northern Sweden, aged 24-76 years. Data was retrieved through a digital survey that collected subjectively reported information on exposure to WBV and biomechanical exposures as well as neck pain. The study included 5,017 participants (response rate 44%). Neck pain was reported by 269 men (11.8%) and 536 women (20.2%). There was a statistically significant association between reporting occupational exposure to WBV half the time or more (adjusted OR 1.91; 95% CI 1.22-3.00) and reporting neck pain. In gender-stratified analyses, the same pattern was observed in men, while there were too few women to determine any association. We conclude that occupational exposure to whole-body vibration was associated with neck pain in men.

sted, utgiver, år, opplag, sider
Taylor & Francis Group, 2024
Emneord
Neck pain, Sweden, ergonomics, occupational health, vibration
HSV kategori
Identifikatorer
urn:nbn:se:umu:diva-208386 (URN)10.1080/00140139.2023.2210792 (DOI)000985155500001 ()37161844 (PubMedID)2-s2.0-85159142546 (Scopus ID)
Forskningsfinansiär
Region Västerbotten, 967266Region Västerbotten, 967867Region Västerbotten, 979090Region Västerbotten, 980109Visare Norr, 939839Visare Norr, 968706
Tilgjengelig fra: 2023-05-23 Laget: 2023-05-23 Sist oppdatert: 2024-07-02bibliografisk kontrollert
Stjernbrandt, A., Pettersson, H., Vihlborg, P., Höper, A. C., Aminoff, A., Wahlström, J. & Nilsson, T. (2024). Raynaud’s phenomenon in the feet of Arctic open-pit miners. International Journal of Circumpolar Health, 83(1), Article ID 2295576.
Åpne denne publikasjonen i ny fane eller vindu >>Raynaud’s phenomenon in the feet of Arctic open-pit miners
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2024 (engelsk)Inngår i: International Journal of Circumpolar Health, ISSN 1239-9736, E-ISSN 2242-3982, Vol. 83, nr 1, artikkel-id 2295576Artikkel i tidsskrift (Fagfellevurdert) Published
Abstract [en]

The literature on Raynaud’s phenomenon (RP) in the feet is scarce, especially in the occupational setting. The primary aim of our study was to investigate the occurrence of RP in the feet of miners. As part of the MineHealth project, written surveys and clinical examinations were completed by 260 Arctic open-pit miners working in northern Sweden and Norway (participation rate 53.6%). Data on RP were collected using standardised colour charts and questionnaire items. Clinical examination included assessing the perception of vibration and pain in both feet. There were eight women and three men who reported RP in the feet. Four also had RP in their hands but none acknowledged any first-degree relatives with the condition. Nine reported exposure to foot-transmitted vibration and one to hand-arm vibration. Seven showed signs of neurosensory injury in the feet. To conclude, the occurrence of RP in the feet of miners was 4.4%. Most cases with RP in the feet did not report the condition in the hands and were exposed to vibration transmitted directly to the feet. There were no reports of a hereditary component. Most cases with RP in the feet also had clinical findings suggestive of peripheral neuropathy in the feet.

sted, utgiver, år, opplag, sider
Taylor & Francis, 2024
Emneord
Cold climate, foot-transmitted vibration, mining, Norway, peripheral nervous system diseases, Raynaud Disease, Sweden, vibration, white toes, whole-body vibration
HSV kategori
Identifikatorer
urn:nbn:se:umu:diva-218867 (URN)10.1080/22423982.2023.2295576 (DOI)38109321 (PubMedID)2-s2.0-85180384200 (Scopus ID)
Forskningsfinansiär
Forte, Swedish Research Council for Health, Working Life and Welfare, 2011-0494Region Västerbotten, 967266Region Västerbotten, 979090
Tilgjengelig fra: 2024-01-05 Laget: 2024-01-05 Sist oppdatert: 2024-07-02bibliografisk kontrollert
Peyre-Costa, D., Stjernbrandt, A., Wahlström, J., Ikäheimo, T. M. & Höper, A. C. (2024). Self-reported exposure to dust and diesel exhaust, respiratory symptoms, and use of respiratory protective equipment among Arctic miners. International Journal of Circumpolar Health, 83(1), Article ID 2343125.
Åpne denne publikasjonen i ny fane eller vindu >>Self-reported exposure to dust and diesel exhaust, respiratory symptoms, and use of respiratory protective equipment among Arctic miners
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2024 (engelsk)Inngår i: International Journal of Circumpolar Health, ISSN 1239-9736, E-ISSN 2242-3982, Vol. 83, nr 1, artikkel-id 2343125Artikkel i tidsskrift (Fagfellevurdert) Published
Abstract [en]

Arctic miners face significant risks from diesel exhaust and dust exposure, potentially leading to adverse respiratory health. Employers must limit harmful exposures, using personal protective equipment (PPE) as a last line of defense. This study explored the association between reported respiratory exposure and symptoms, and PPE training and usage. Data from the MineHealth study (2012–2014) included a total of 453 Arctic open pit miners in Norway, Sweden, and Finland. Participants answered questions on exposure to dust and diesel exhaust, respiratory symptoms, and PPE use, in addition to age, gender, BMI, smoking, and self-rated health. Estimated exposure to dust was common, reported by 91%, 80%, and 82% and that of diesel exhaust by 84%, 43%, and 47% of workers in Sweden, Finland, and Norway, respectively. Reported dust exposure was significantly related to respiratory symptoms (OR 2.2, 95% CI 1.3–3.7), diesel exposure increased the occurrence of wheezing (OR 2.6, 95% CI 1.3–5.4). PPE use varied between the studied mines. Non-use was common and related to reduced visibility, wetness, skin irritation and fogging of the respiratory PPE. Future research should employ more precise exposure assessment, respiratory function as well as explore the reasons behind the non-compliance of PPE use.

sted, utgiver, år, opplag, sider
Taylor & Francis Group, 2024
Emneord
air pollutant, Arctic, open-pit mining, personal protective equipment, respiratory symptoms
HSV kategori
Identifikatorer
urn:nbn:se:umu:diva-223626 (URN)10.1080/22423982.2024.2343125 (DOI)38626426 (PubMedID)2-s2.0-85190506069 (Scopus ID)
Forskningsfinansiär
Forte, Swedish Research Council for Health, Working Life and Welfare, 2011–0494
Tilgjengelig fra: 2024-04-25 Laget: 2024-04-25 Sist oppdatert: 2024-07-02bibliografisk kontrollert
Mboya, I. B., Fritz, J., da Silva, M., Sun, M., Wahlström, J., Magnusson, P. K. .., . . . Stocks, T. (2024). Time trends of the association of body mass index with mortality in 3.5 million young Swedish adults. Annals of Epidemiology, 97, 23-32
Åpne denne publikasjonen i ny fane eller vindu >>Time trends of the association of body mass index with mortality in 3.5 million young Swedish adults
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2024 (engelsk)Inngår i: Annals of Epidemiology, ISSN 1047-2797, E-ISSN 1873-2585, Vol. 97, s. 23-32Artikkel i tidsskrift (Fagfellevurdert) Published
Abstract [en]

Purpose: We investigated time trends of the obesity-mortality association, accounting for age, sex, and cause-specific deaths.

Methods: We analysed pooled nationwide data in Sweden for 3,472,310 individuals aged 17–39 years at baseline in 1963–2016. Cox regression and flexible parametric survival models investigated BMI-mortality associations in sub-groups of sex and baseline calendar years (men: <1975, 1975–1985, ≥1985 and women: <1985, 1985–1994, ≥1995).

Results: Comparing men with obesity vs. normal weight, all-cause and “other-cause” mortality associations decreased over periods; HR (95% CI) 1.92 (1.83–2.01) and 1.70 (1.58–1.82) for all-cause and 1.72 (1.58–1.87) and 1.40 (1.28–1.53) for “other-cause” mortality in <1975 and ≥1985, but increased for CVD mortality; HR 2.71 (2.51–2.94) and 3.91 (3.37–4.53). Higher age at death before 1975 coincided with more obesity-related deaths at higher ages. Furthermore, the all-cause mortality association for different ages in men showed no clear differences between periods (p-interaction=0.09), suggesting no calendar effect after accounting for attained age. Similar, but less pronounced, results were observed in women. Associations with cancer mortality showed no clear trends in men or in women.

Conclusions: Accounting for differences in age and death causes between calendar periods when investigating BMI-mortality time trends may avoid misinterpreting the risks associated with obesity over time.

sted, utgiver, år, opplag, sider
Elsevier, 2024
Emneord
Body mass index, Mortality, Time trends
HSV kategori
Identifikatorer
urn:nbn:se:umu:diva-228070 (URN)10.1016/j.annepidem.2024.07.043 (DOI)39019242 (PubMedID)2-s2.0-85199035309 (Scopus ID)
Prosjekter
MONICABiobank SwedenSIMPLER
Forskningsfinansiär
Swedish Research Council, 2017–00650Swedish Research Council, 2017–00644Swedish Research Council, 2021–00160Swedish Cancer Society, 23 0633 SIASwedish Research Council, 2021-01934Lund University, STYR 2019/2046Karolinska Institute, 2021–00180
Tilgjengelig fra: 2024-07-31 Laget: 2024-07-31 Sist oppdatert: 2025-02-11bibliografisk kontrollert
Prosjekter
Orsaker till sjukdomar i rörelseorganen och dess långsiktiga konsekvenser ? en registerstudie [2016-01016_Forte]; Umeå universitet
Organisasjoner
Identifikatorer
ORCID-id: ORCID iD iconorcid.org/0000-0002-2359-509X