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Objectives: Chronic pain is a major health problem and is more common among women than men. Interdisciplinary pain rehabilitation programmes (IPR) are effective in reducing pain and restoring function for patients with chronic pain. However, in Sweden, immigrants who do not speak Swedish are commonly not selected for participation in IPR. There is thus a knowledge gap regarding whether IPR has positive effects for immigrants with chronic pain and inadequate Swedish language skills. The aim of this study was to investigate outcomes in patients with chronic pain and inadequate Swedish language skills at one-year follow-up after participation in an IPR with language interpreters, both on the whole group level and separately for women and men, and in comparison with a reference group of patients.

Methods: Design: prospective multi-centre cohort study. Patients: 74 patients (60 women and 14 men). Pain intensity, anxiety and depression, health-related quality of life, fear of movement and the number of doctor visits due to pain were evaluated at baseline, at treatment conclusion (except for doctor visits) and one year after the programme. Patients were compared with a reference group comprising Swedish-speaking patients in a standard interdisciplinary pain rehabilitation programme (135 patients (122 women and 13 men)).

Results: At one-year follow-up, the patients showed significant improvements in pain intensity, depression, and fear of movement, and when subgrouping, the female patients showed significant improvements in the same variables: pain intensity (p=0.002), depression (p=0.015), and fear of movement (p=0.007). Anxiety was significantly deteriorated, both for the whole group and for the female patients (p=0.011). The men did not improve, but low numbers preclude statistics or conclusions. On the whole group level, there was also a significantly reduced number of doctor visits due to pain (p<0.001) at one-year follow-up. Compared to those in the reference group, the patients rated themselves significantly poorer before the programme for the variables measured over time (p=/<0.004). All variables improved significantly for the patients in the reference group at one-year follow-up.

Conclusions: Patients with chronic pain and inadequate language skills in the Swedish language seem to benefit from participating in an interdisciplinary pain rehabilitation programme with language interpreters. The result could be of value for the further development of such rehabilitation programmes, but further studies are needed regarding meńs needs in and after a rehabilitation programme.

Background: Care should be neutral and equal, but normative beliefs may impact the interaction between patients and healthcare professionals in pain management.

Objectives: To explore how patients with jaw and neck pain perceive pain management and the interaction with healthcare professionals in relation to intersectionality, with a specific focus on gender.

Methods: Recruitment was performed at a specialist dentistry clinic in Sweden. Inclusion criteria were patients aged 18-70 years, reporting jaw and neck pain and understanding the Swedish language. Exclusion criteria were rheumatic disease, temporomandibular joint arthralgia or arthritis. Using purposive sampling, 16 patients (11 women) aged 19-56 were interviewed using individual semi-structured interviews. The analysis was performed using thematic analysis.

Results: The analysis resulted in the theme: 'Intersectional bias in healthcare - the inequity borne by the patients', with five subthemes that entailed different types of bias related to the participants' personal characteristics and their interaction with healthcare professionals. Health-related stigmata was one subtheme described among participants, resulting in labelling and burden in the encounter. Other subthemes also described bias in relation to biological differences among pain patients and patients not being taken seriously due to, for example, female gender and younger age. Two subthemes also described bias in relation to the healthcare professionals' gender and age.

Conclusion: Normative beliefs have a negative impact on the interaction between patients and healthcare professionals in pain management. Since patient-provider interaction should be neutral and equal, intersectional bias should be acknowledged to prevent health and care inequalities.Keywords: gender differences; healthcare disparities; intersectionality; neck pain; temporomandibular joint disorders.

Objective: To examine stroke survivors’ satisfaction with hospital-based outpatient rehabilitation and its association with life satisfaction and health-related quality of life (HRQoL), and whether sex and age affect possible associations. 

Design: A longitudinal national register study. 

Methods: Data from the Swedish national quality register were used and included 1,068 patients with stroke performing outpatient rehabilitation. Self-reported questionnaires collected on admission, discharge, and at 1-year follow-up were analysed. Regression analyses were used to assess possible associations between patient satisfaction and life satisfaction (Life Satisfaction Questionnaire, LiSat-11) and HRQoL (EuroQol Five Dimensions questionnaire, EQ-5D).

Results: Over 71% of the included patients were satisfied with their rehabilitation process on discharge. Satisfied patients also reported higher scores on global LiSat-11 and higher EQ-5D values. Older patients (> 58 years) satisfied with their rehabilitation process were more likely to be satisfied with global LiSat-11. Women dissatisfied with the rehabilitation process had lower EQ-5D values on discharge.

Conclusion: Patient satisfaction with hospital-based outpatient rehabilitation was associated with life satisfaction and HRQoL. Potential differences linked to sex and age support the importance of individually tailored rehabilitation strategies. Evaluating self-reported outcomes and experiences over time is essential for improving long-term recovery and for further development of person-centred stroke rehabilitation.

Fatigue is common in patients with chronic pain, but the neural underpinning of this symptom is still poorly understood. In this study, we aimed to investigate resting state connectivity correlates of pain and fatigue in patients with chronic pain. Twenty-four women with chronic pain, and 22 age-matched healthy controls underwent resting state functional magnetic resonance imaging (fMRI), performed a 20-min fatiguing attention task, and underwent an additional resting state fMRI examination. Patients with chronic pain reported a higher degree of both fatigue (p < 0.001) and pain (p < 0.001) than healthy controls. Significant group differences in connectivity to the lateral visual network, the salience network, the auditory network, the executive control network, and especially in regions within the default mode network were detected before the task. After the task, these differences were no longer statistically detectable, and only differences in connectivity between the basal ganglia network and the prefrontal areas between groups were observed. While differences in functional connectivity related to pain were present before performance of the task, only differences related to fatigue were found after the task. This finding indicates that processing of fatigue might overshadow processing of pain after performance of a fatiguing attention task in patients with chronic pain.

Purpose: Cognitive reserve and neuropsychological test results are linked to outcomes after acquired brain injury (ABI), but their interaction and their impact on different types of outcomes remains to be explored. This study aimed to explore how cognitive reserve, measured by education, is related to neuropsychological outcomes, return-to-work and life satisfaction after ABI.

Methods: Long term follow-up of 83 patients with ABI, 5–15 years after specialized brain injury rehabilitation. Logistic regression was used to analyze the relationship between independent variables and outcomes (return-to-work and life satisfaction).

Results: Return-to-work was associated with cognitive reserve (OR = 1.31, p = 0.024), age (OR = 0.95, p = 0.042), general fatigue (OR = 0.77, p = 0.034), and Cognitive Profiency Index (measures of working memory and processing speed, OR = 1.06, p = 0.037). Verbal and spatial abilities were related to education, but not to return-to-work. General fatigue was related to satisfaction with mental health in both univariate (OR = 0.78, p = 0.008) and multivariate analyses (OR = 0.8, p = 0.037), but no other variables were significantly associated with life satisfaction in multivariate analyses.

Conclusion: Patients with lower cognitive reserve paired with slower processing speed and poor working memory may need additional support for successful return-to-work, while life satisfaction appears to depend more on other factors.

OBJECTIVES: Chronic pain is a major global public-health issue. In Sweden, 20% adults report moderate to severe chronic pain, with 7% continuously seeking healthcare. Shortcomings in treatment, accessibility, and knowledge in healthcare for chronic pain have previously been reported. A generic treatment structure from primary to specialized care and rehabilitation was missing. This study aims to describe the development process for the creation of a person-centered and coherent care (P3C) pathway for adults with chronic pain in Sweden.

METHODS: A National Action Group with expertise in pain medicine, rehabilitation medicine, psychiatry, anesthesiology, neurosurgery, general medicine, nursing, psychology, physiotherapy, occupational therapy, and patient representation was commissioned to develop the pathway following a stepwise co-designed approach, which included mapping current situation, goals, measures and indicators of the pathway, assessment of consequences and anchoring the process.

RESULTS: Goals were based on challenges identified in the mapping, including improvements in patient's well-being, continuity during and between care contacts, timely self-management, communication between levels of care, and knowledge about pain. Points of pathway entrance and exit were described. Measures focused on areas such as early pain analysis, biopsychosocial approach to assessment and treatment, early rehabilitation plan, teamwork, dialogue and joint plans between levels of care, patient participation, and education on pain and its consequences. Process and outcome indicators, and a report on benefits and risks for patients, ethical aspects, costs, and impacts of the pathway on other areas of healthcare were included.

CONCLUSIONS: The P3C pathway addressed the challenges described by patients and practitioners. By being person-centered and coherent, it can promote patient empowerment and equality in care, with emphasis on early and timely interventions, dialogue between patients and practitioners and between levels of care, self-management of pain instead of prolonged medical intervention, value-driven and coordinated care contacts, and increased knowledge about chronic pain, based on existing evidence and experience.

Objectives: Fatigue is common in patients with chronic pain. However, there is a knowledge gap concerning performance fatigue, cognitive fatigability, and its neural correlates in this patient group. In this study, we therefore aimed to investigate the presence of cognitive fatigability and its neural correlates in patients with chronic pain using functional magnetic resonance imaging (fMRI).

Methods: In this study 24 women with chronic pain and 22 healthy controls, aged 18–45 years, underwent a 20-minute psychomotor vigilance task (PVT) assessing reaction time during blood-oxygen-level dependent (BOLD) fMRI. Reaction time and BOLD signal changes were analyzed using dual regression.

Results: The patients showed significant cognitive fatigability, i.e., prolonged reaction time, during the PVT, while the controls maintained a stable performance (p = .018). No significant neural time on task effect was found on BOLD fMRI. There were however differences in the brain areas activated between the groups throughout task performance. Patients with chronic pain showed stronger activation primarily in prefrontal cortex, including motor areas, while healthy controls demonstrated stronger activation particularly in the left middle orbital gyrus and right insula.

Conclusion: The study indicates that the phenomenon of cognitive fatigability is present in patients with chronic pain. Also, the presence of chronic pain was associated with increased activation in brain regions related to motor and cognitive control, possibly reflecting compensatory mechanisms. Conversely, healthy controls showed higher activity in regions active in motivation, reward, and decision-making, suggesting more motivation-driven and efficient processing.

Further studies are needed to validate the results.

Background: Individuals with more education com-monly have better outcome after brain injury, often attributed to cognitive reserve. However, evidence suggests that individuals with more education have better access to specialized care, potentially affec-ting outcomes.

Objective: To investigate differences in healthcare usage based on cognitive reserve and examine the relationship between healthcare usage and outcomes after stroke and traumatic brain injury.

Design: An observational cohort study with health-care usage data from 3 years before to 4 years after injury, interviewing patients 5–15 years after injury. Patients: A total of 83 participants suffering a stroke or traumatic brain injury.

Results: Healthcare usage over time varied based on educational level (repeated measures ANOVA, F(2, 227) = 4.17, p = 0.008). The differences in healthcare usage between educational levels was significant during the injury year (F(81) = –5.47, p = 0.022). Higher education implied more healthcare usage. Linear regression, controlling for possible confoun-ders, confirmed the relationship between education and healthcare usage, (β = 4.3, p = 0.022). Health-care usage was significantly related to long-term life satisfaction, but not to return to work.

Conclusion: Individuals with more education recei-ved more healthcare in the year after traumatic brain injury or stroke. However, this was not related to long-term outcome regarding return to work, but we found a relationship between healthcare usage and life satisfaction.

Introduction: The objective of this study was to evaluate the effects of Constraint-Induced Movement Therapy (CIMT) on hemiplegic shoulder pain (HSP), shoulder range of motion (ROM) and upper extremity motor function in stroke patients.

Methods: This longitudinal intervention cohort study was performed in an outpatient clinic without a control group. Participants underwent individually tailored CIMT with a patient therapist ratio of 4:1 for 6 h/day, 5 days/week for 2 consecutive weeks, including daily shoulder strength and joint motion training. A total of 221 (101 with and 120 without pre-CIMT HSP) middle-aged (median 54 years) persons at sub-acute or chronic phases after stroke were included in the study. The Fugl-Meyer Assessment (FMA) subscale for pain was used for defining and scoring HSP at passive motion (sum of four directions of movement, maximum 8 points indicating no pain). Passive and active shoulder ROM (sum of flexion and abduction) were assessed. Upper extremity motor function was assessed with B. Lindmark Motor Assessment. Assessments were done pre- and post-CIMT and at 3-month follow-up. Comparisons were stratified by subgroups with- and without HSP.

Results: In the subgroup with pre-CIMT HSP, median HSP score at passive movement was reduced (FMA shoulder pain score increased) from pre- to post-CIMT from 5 points to 7 points post-CIMT, (p < 0.001, Effect size (ES) 0.68). Median active ROM increased from 230° to 308° (p < 0.001, ES 0.72) and median passive ROM increased from 350° to 360° (p < 0.001, ES 0.44). Median motor function improved from 42 to 49 points (p < 0.001, ES 0.92). In the subgroup without pre-CIMT HSP no statistically significant increase of HSP was seen and no clinically significant changes observed for active or passive ROM after CIMT. Median motor function improved from 52 to 56 points (p < 0.001, ES 0.71). All improvements persisted at 3-month follow-up.

Conclusion: CIMT in an outpatient clinical setting may be a feasible treatment to decrease HSP and to improve shoulder ROM and upper extremity motor function among middle-aged persons in the subacute and chronic phases after stroke. Results need to be confirmed in an RCT setting.

OBJECTIVES: Most patients with chronic pain are identified and managed in primary care (PC). Chronic pain management is challenging, which is manifested by increased healthcare utilization (HCU) in this patient group. The interdisciplinary pain rehabilitation program (IPRP) is the gold standard treatment for patients with chronic pain but is scarcely used in PC. The aim of this study was to evaluate the HCU of patients with chronic pain in PC 1 year before and 1 year after an IPRP by examining the distribution of costs and resources.

METHODS: This retrospective cohort study combined data from a national pain registry and HCU data from regional administrative registries, including 146 patients who participated in an IPRP in PC. The outcome measure was the number of outpatient healthcare contacts. Costs and the distribution of resources were compared across the two measurement intervals using paired t-tests. HCU costs were described from a healthcare provider perspective.

RESULTS: HCU decreased by 16% in the year following IPRP compared to the year before. Costs for outpatient visits dropped by 12% or €434 per participant. Visits to physiotherapists and general practitioners decreased the most, by 31% (p = 0.048) and 23% (p < 0.001) respectively. Visits to nurses, occupational therapists, and psychologists/social workers in turn increased marginally (6%, 5% vs 10%).

CONCLUSIONS: IPRP in PC may lead to reduced HCU, freed resources, and streamlined chronic pain management. The study offers valuable insights into expected changes in HCU for chronic pain patients after an IPRP and how these changes may impact daily activities at the PC center.