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2023 (English)In: Acta Odontologica Scandinavica, ISSN 0001-6357, E-ISSN 1502-3850, Vol. 81, no 4, p. 325-331Article in journal (Refereed) Published
Abstract [en]
Objective: The aim of this case-control study was to investigate whether cognitively impaired individuals have a higher burden of calcified carotid artery atheroma (CCAA) than controls without cognitive impairment.
Material and methods: The study included 154 cases with Alzheimer’s disease (n = 52), mild cognitive impairment (n = 51), or subjective cognitive decline (n = 51) diagnosed at a university memory clinic. Seventy-six cognitively healthy controls were sampled through the Swedish population register. All participants underwent clinical oral and panoramic radiographic examinations. Two oral and maxillofacial radiologists performed blinded analyses of the panoramic radiographs for signs of CCAA, which was registered as absent or present and, if present, unilateral or bilateral. Consensus assessment was used for all statistical analyses.
Results: CCAA was common (40%) in this middle-aged and older Swedish population. We found no differences in the prevalence of CCAA between cases and controls (40% vs. 42%).
Conclusion: Cognitively impaired patients do not have a higher burden of CCAA than matched controls without cognitive impairment.
Place, publisher, year, edition, pages
Taylor & Francis Group, 2023
Keywords
Alzheimer’s disease, cardiovascular disease, cognitive disorders, dentistry, panoramic radiography
National Category
Dentistry Radiology, Nuclear Medicine and Medical Imaging Geriatrics
Research subject
Odontology
Identifiers
urn:nbn:se:umu:diva-201842 (URN)10.1080/00016357.2022.2152863 (DOI)000900707600001 ()36538364 (PubMedID)2-s2.0-85144537909 (Scopus ID)
Funder
Stockholm County Council
2022-12-212022-12-212023-06-19Bibliographically approved