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Hörnsten, Carl
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Publications (10 of 27) Show all publications
Holmlund, L., Hörnsten, C., Valham, F., Olsson, K., Hörnsten, Å. & Hellström Ängerud, K. (2024). Illness perceptions and health-related quality of life in women and men with atrial fibrillation. Journal of Cardiovascular Nursing, 39(1), 49-57
Open this publication in new window or tab >>Illness perceptions and health-related quality of life in women and men with atrial fibrillation
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2024 (English)In: Journal of Cardiovascular Nursing, ISSN 0889-4655, E-ISSN 1550-5049, Vol. 39, no 1, p. 49-57Article in journal (Refereed) Published
Abstract [en]

BACKGROUND: Health-related quality of life (HRQoL) is worse in patients with atrial fibrillation (AF) compared with other populations. Factors affecting HRQoL in patients with AF are not fully clarified. Illness perceptions are important determinants of disease management and may affect HRQoL.

OBJECTIVE: The aims of this study were to describe illness perceptions and HRQoL in women and men with AF and to explore the relationship between illness perceptions and HRQoL in patients with AF.

METHODS: This cross-sectional study included 167 patients with AF. Patients completed the Revised Illness Perception Questionnaire and HRQoL questionnaires: Arrhythmia-Specific questionnaire in Tachycardia and Arrhythmias, the three-level version of the EuroQol 5-dimensional questionnaire, and EuroQol visual analog scale. Subscales of the Revised Illness Perception Questionnaire significant in correlation analysis with the Arrhythmia-Specific questionnaire in Tachycardia and Arrhythmias HRQoL total scale were included in a multiple linear regression model.

RESULTS: Mean age was 68.7 ± 10.4 years, and 31.1% were women. Women reported lower personal control (P = .039) and worse HRQoL measured with the Arrhythmia-Specific questionnaire in Tachycardia and Arrhythmias physical subscale (P = .047) and the EuroQol visual analog scale (P = .044) compared with men. Illness identity (P < .001), consequences (P = .031), emotional representation (P = .014), and timeline cyclical (P = .022) were related to and adversely affected HRQoL.

CONCLUSIONS: This study found a relationship between illness perceptions and HRQoL. Some subscales of illness perceptions negatively affected HRQoL in patients with AF, which indicates that efforts to change illness perceptions may be helpful in improving HRQoL. Patients should be given the opportunity to talk about the disease, their symptoms, their emotions, and the consequences of the disease to enable increased HRQoL. A challenge for healthcare will be to design support for each patient based on his/her illness perceptions.

Place, publisher, year, edition, pages
Wolters Kluwer, 2024
Keywords
atrial fibrillation, health-related quality of life, illness perceptions
National Category
Nursing
Identifiers
urn:nbn:se:umu:diva-206996 (URN)10.1097/JCN.0000000000000995 (DOI)37074949 (PubMedID)2-s2.0-85178651164 (Scopus ID)
Available from: 2023-04-25 Created: 2023-04-25 Last updated: 2023-12-22Bibliographically approved
Holmlund, L., Hörnsten, C., Hörnsten, Å., Olsson, K., Valham, F. & Hellström Ängerud, K. (2024). More positive patient-reported outcomes in patients newly diagnosed with atrial fibrillation: a comparative longitudinal study. European Journal of Cardiovascular Nursing
Open this publication in new window or tab >>More positive patient-reported outcomes in patients newly diagnosed with atrial fibrillation: a comparative longitudinal study
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2024 (English)In: European Journal of Cardiovascular Nursing, ISSN 1474-5151, E-ISSN 1873-1953Article in journal (Refereed) Epub ahead of print
Abstract [en]

Aims: To compare patient-reported outcomes (PROs) in patients newly (<6 months) diagnosed with atrial fibrillation (AF) with those who have had a longer diagnosis (≥6 months) and to investigate whether or not these outcomes change over a 6-month period.

Methods and results: In this longitudinal survey study, 129 patients with AF completed the Revised Illness Perception Questionnaire, the Arrhythmia-Specific questionnaire in Tachycardia and Arrhythmia, and the Hospital Anxiety and Depression Scale at baseline and after 6 months. At baseline, patients newly diagnosed with AF (n = 53), compared with patients with a previous diagnosis (n = 76), reported AF as more temporary (P = 0.003) and had a higher belief in personal and treatment control (P = 0.004 and P = 0.041, respectively). At a 6-month follow-up, patients newly diagnosed reported a lower symptom burden (P = 0.004), better health-related quality of life (HRQoL); (P = 0.015), and a higher personal control (P < 0.001) than patients previously diagnosed. Over time, in patients newly diagnosed, symptom burden and the anxiety symptom score decreased (P = 0.001 and P = 0.014, respectively) and HRQoL improved (P = 0.002).

Conclusion: Patients newly diagnosed with AF reported more positive PROs both at baseline and at a 6-month follow-up than patients with a previous diagnosis of AF. Therefore, it is important to quickly capture patients newly diagnosed to support their belief in their own abilities. Such support may, alongside medical treatments, help patients manage the disease, which may lead to reduced symptom burden and better HRQoL over time.

Place, publisher, year, edition, pages
Oxford University Press, 2024
Keywords
Anxiety, Atrial fibrillation, Depression, Health-related quality of life, Newly diagnosed, Patient-reported outcomes, Symptom burden
National Category
Nursing
Identifiers
urn:nbn:se:umu:diva-222452 (URN)10.1093/eurjcn/zvad139 (DOI)
Funder
Umeå UniversitySwedish Heart Lung Foundation
Available from: 2024-03-18 Created: 2024-03-18 Last updated: 2024-03-18
Snellman, S., Hörnsten, C., Olofsson, B., Gustafson, Y., Lövheim, H. & Niklasson, J. (2024). Validity and test–retest reliability of the Swedish version of the Geriatric Depression Scale among very old adults. BMC Geriatrics, 24(1), Article ID 261.
Open this publication in new window or tab >>Validity and test–retest reliability of the Swedish version of the Geriatric Depression Scale among very old adults
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2024 (English)In: BMC Geriatrics, E-ISSN 1471-2318, Vol. 24, no 1, article id 261Article in journal (Refereed) Published
Abstract [en]

Background: The Geriatric Depression Scale (GDS) has shown good validity and reliability, but few studies have examined the GDS among very old adults or the Swedish translation.

Objectives: Evaluate the validity and reliability of the Swedish version of GDS-15 among very old adults.

Methods: In the Umeå85 + /GErontological Regional DAtabase (GERDA) study, 387 participants were assessed with both the GDS-15 and the Montgomery-Åsberg Depression Rating Scale (MADRS). The mean age was 91 years. Concurrent validity between the scales was calculated using Spearman's correlation. We used the Diagnostic and Statistical Manual of Mental Disorders (DSM) V symptom criteria for depression based on MADRS item scores to define depression. We calculated the Area Under the Curve (AUC) and found an optimal cut-off. A convenience sample with 60 individuals was used to calculate test–retest reliability with Cohen’s kappa and Intraclass Correlation Coefficient (ICC).

Results: Spearman's correlation coefficients between total scores for GDS-15 and MADRS were 0.60. Cronbach's alpha for the whole scale was 0.73. The AUC was 0.90 for distinguishing major depression, and the recommended cut-off of ≥ 5 showed a sensitivity of 95.2% and specificity of 65.8%. The test–retest showed that Cohen’s kappa was substantial (0.71) and the ICC was excellent (0.95).

Conclusions: The Swedish version of the GDS-15 showed good validity and reliability among very old adults. The generally recommended cut-off of ≥ 5 seems reasonable to use with the Swedish version and among very old adults.

Place, publisher, year, edition, pages
BioMed Central (BMC), 2024
Keywords
Aged 80 and over, Depression, Psychiatric status rating scales, Psychometrics, ROC curve
National Category
Geriatrics Nursing
Identifiers
urn:nbn:se:umu:diva-222888 (URN)10.1186/s12877-024-04869-7 (DOI)001187389700003 ()38500031 (PubMedID)2-s2.0-85188072998 (Scopus ID)
Funder
Swedish Research Council, K2014– 99X-22610–01–6Region VästerbottenNorrbotten County CouncilThe Dementia Association - The National Association for the Rights of the Demented
Available from: 2024-04-08 Created: 2024-04-08 Last updated: 2024-04-08Bibliographically approved
Fjällström, P., Hörnsten, C., Lilja, M., Hultstrand, C., Coe, A.-B. & Hajdarevic, S. (2023). Reduction in the diagnostic interval after the introduction of cancer patient pathways for colorectal cancer in northern Sweden. Scandinavian Journal of Primary Health Care, 41(3), 287-296
Open this publication in new window or tab >>Reduction in the diagnostic interval after the introduction of cancer patient pathways for colorectal cancer in northern Sweden
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2023 (English)In: Scandinavian Journal of Primary Health Care, ISSN 0281-3432, E-ISSN 1502-7724, Vol. 41, no 3, p. 287-296Article in journal (Refereed) Published
Abstract [en]

Objective: To compare the diagnostic interval for patients with colorectal cancer before and after the introduction of cancer patient pathways in northern Sweden.

Design: A retrospective study comparing two cohorts (2012 and 2018) of patients diagnosed with colorectal cancer before and after the introduction of cancer patient pathways in 2016.

Setting: Three counties in northern Sweden with large sparsely populated areas and some cities (637143 residents ∼5.1 residents/km2).

Subjects: Patients were included from the Swedish Cancer Register. Electronic health records reviews were performed and linked to socioeconomic data from Statistics Sweden.

Main outcome measures: Differences in the diagnostic intervals, the patient intervals and the characteristics associated with the longest diagnostic intervals and investigations starting at the emergency department.

Results: The two cohorts included 411 patients in 2012 and 445 patients in 2018. The median diagnostic interval was reduced from 47 days (IQI 18–99) to 29 days (IQI 9–74) (p < 0.001) after the introduction of cancer patient pathways in general. Though for the cases of cancer in the right-side (ascended) colon, the reduction of the diagnostic interval was not observed and it remained associated with investigations starting at the emergency department.

Conclusion: Our results indicate that cancer patient pathways contributed to an improvement in the diagnostic interval for patients with colorectal cancer in general, yet not for patients with cancer in the right-side colon.

Implication: In general, cancer patient pathways seem to reduce the diagnostic interval for colorectal cancer but it is not a sufficient solution for all colorectal cancer localisations.

Place, publisher, year, edition, pages
Taylor & Francis, 2023
Keywords
cancer patient pathways, Colorectal cancer, diagnostic interval, primary healthcare, socioeconomic factors, symptoms, time to diagnosis
National Category
Cancer and Oncology Nursing
Identifiers
urn:nbn:se:umu:diva-212509 (URN)10.1080/02813432.2023.2234003 (DOI)001025227600001 ()37450480 (PubMedID)2-s2.0-85165303497 (Scopus ID)
Available from: 2023-08-01 Created: 2023-08-01 Last updated: 2023-09-04Bibliographically approved
Öhlin, J., Toots, A., Dahlin Almevall, A., Littbrand, H., Conradsson, M., Hörnsten, C., . . . Söderberg, S. (2022). Concurrent validity of the International Physical Activity Questionnaire adapted for adults aged ≥ 80 years (IPAQ-E 80 +) - tested with accelerometer data from the SilverMONICA study. Gait & Posture, 92, 135-143
Open this publication in new window or tab >>Concurrent validity of the International Physical Activity Questionnaire adapted for adults aged ≥ 80 years (IPAQ-E 80 +) - tested with accelerometer data from the SilverMONICA study
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2022 (English)In: Gait & Posture, ISSN 0966-6362, E-ISSN 1879-2219, Vol. 92, p. 135-143Article in journal (Refereed) Published
Abstract [en]

Background: Physical activity and sedentary behavior vary across the life span, and in very old people activity behavior can vary considerably over 24 h. A physical activity questionnaire adapted for this age group is lacking. This study was conducted to validate such a newly developed questionnaire suitable for use in very old people.

Research question: Is the International Physical Activity Questionnaire adapted for adults aged ≥ 80 years (IPAQ-E 80 +) a valid measure of physical activity in very old people?

Methods: Seventy-six participants (55.3% women) with a mean age of 84.4 ± 3.8 years wore accelerometers for ≥ 5 consecutive days, and completed the IPAQ-E 80 +. Spearman's rho and Bland-Altman plots were used to analyze the validity of IPAQ-E 80 + against accelerometer measures. Analyses were conducted for the separate items sitting, laying down at daytime and nighttime, walking, moderate to vigorous (MV) walking, and moderate to vigorous physical activity (MVPA), and the summary measures: total inactive time, sedentary time (i.e. lying down at daytime + sitting), total active time, and total MVPA + MV walking.

Results: The IPAQ-E 80 + correlated with the accelerometer measures of total inactive- (r = 0.55, p < 0.001), sedentary- (r = 0.28, p = 0.015), walking- (r = 0.54 p < 0.001) and total active- (r = 0.60, p < 0.001) times, but not with measures of intensity of walking or physical activity; MV walking (r = 0.06, p = 0.58), MVPA (r = 0.17, p = 0.13).

Significance: In this study the IPAQ-E 80 + showed fair to substantial correlations with accelerometers, and it therefore seems able to rank very old people according to levels of PA (total inactive-, sedentary-, and total active time, and walking time). The IPAQ-E 80 + seems promising for use in studies investigating associations between activity behavior and health in this population. Further investigation is needed to determine whether the IPAQ-E 80 + can accurately measure PA intensity.

Place, publisher, year, edition, pages
Elsevier, 2022
Keywords
Validity, Physical activity questionnaire, Sedentary behavior, Very old people, Accelerometry
National Category
Physiotherapy Geriatrics Public Health, Global Health, Social Medicine and Epidemiology
Research subject
physiotherapy
Identifiers
urn:nbn:se:umu:diva-187217 (URN)10.1016/j.gaitpost.2021.11.019 (DOI)000788079500011 ()34847411 (PubMedID)2-s2.0-85120962874 (Scopus ID)
Funder
Swedish Research Council Formas, 2016-01074Swedish Research Council, K2014-99X-22610-01-6
Note

Originally included in thesis in manuscript form.

Available from: 2021-09-06 Created: 2021-09-06 Last updated: 2023-09-05Bibliographically approved
Burman, M., Hörnsten, C., Gustafson, Y., Olofsson, B. & Nordström, P. (2022). Obesity may increase survival, regardless of nutritional status: a Swedish cohort study in nursing homes. BMC Geriatrics, 22(1), Article ID 655.
Open this publication in new window or tab >>Obesity may increase survival, regardless of nutritional status: a Swedish cohort study in nursing homes
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2022 (English)In: BMC Geriatrics, ISSN 1471-2318, E-ISSN 1471-2318, Vol. 22, no 1, article id 655Article in journal (Refereed) Published
Abstract [en]

Background: To investigate the associations between the body mass index (BMI), Mini Nutritional Assessment-Short Form (MNA-SF) scores, and 2-year mortality.

Methods: A nationwide cohort study using data from a national quality register of older (age ≥ 65 years) nursing home residents (N = 47,686). Individuals were categorized according to BMI as underweight (< 18.5 kg/m2), normal-weight (18.5-24.9 kg/m2), overweight (25.0-29.9 kg/m2), and obese (class I, 30.0-34.9 kg/m2; class II, 35.0-39.9 kg/m2; class III, ≥ 40.0 kg/m2). Participants' nutritional status were categorized as good (MNA-SF score 12-14), at risk of malnutrition (MNA-SF score 8-11), or malnutrition (MNA-SF score 0-7). Associations with mortality were analysed using Cox proportional-hazards models.

Results: At baseline, 16.0% had obesity, and 14.6% were malnourished. During 2 years of follow-up, 23,335 (48.9%) individuals died. Compared with normal-weight individuals, mortality was greater among underweight individuals [hazard ratio (HR) 1.62, 95% confidence interval (CI) 1.55-1.69] and lesser among individuals with class I (HR 0.63, 95% CI 0.60-0.66), class II (HR 0.62, 95% CI 0.56-0.68), and class III (HR 0.80, 95% CI 0.69-0.94) obesity. Compared with individuals with good nutritional status, mortality was increased for those with malnutrition (HR 2.98,95% CI 2.87-3.10). Lower mortality among obese individuals was also seen in subgroups defined according to MNA-SF scores.

Conclusions: Among older nursing home residents, obesity, including severe obesity, was associated with lower 2-year mortality. Higher BMIs were associated with better survival, regardless of nutritional status according to MNA-SF.

Place, publisher, year, edition, pages
BioMed Central, 2022
Keywords
Mortality, Nutritional status, Obesity, Older nursing home residents
National Category
Geriatrics
Identifiers
urn:nbn:se:umu:diva-182792 (URN)10.1186/s12877-022-03356-1 (DOI)000838662600003 ()35948885 (PubMedID)2-s2.0-85135815690 (Scopus ID)
Funder
Swedish Research Council, K2014-99X-22610-01-6Västerbotten County Council
Note

Originally included in thesis in manuscript form. 

Available from: 2021-05-04 Created: 2021-05-04 Last updated: 2022-09-09Bibliographically approved
Öhlin, J., Toots, A., Littbrand, H., Wennberg, P., Olofsson, B., Gustafson, Y., . . . Söderberg, S. (2022). Physical activity in late middle- to older-aged people and dementia, cognitive, and physical function two decades later. Dementia and Geriatric Cognitive Disorders, 51, 135-141
Open this publication in new window or tab >>Physical activity in late middle- to older-aged people and dementia, cognitive, and physical function two decades later
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2022 (English)In: Dementia and Geriatric Cognitive Disorders, ISSN 1420-8008, E-ISSN 1421-9824, Vol. 51, p. 135-141Article in journal (Refereed) Published
Abstract [en]

Introduction: Low physical activity (PA) is a potential risk factor for dementia and cognitive impairment. However, few studies have focused on very old people (aged ≥80 years), the age group with highest prevalence of dementia. The aim was to investigate if PA associated with subsequent dementia, cognitive function, and gait speed (GS), in very old people.

Methods: A population-based survey was conducted in 1999 and followed-up between 2016 and 2019 in participants ≥80 years. Altogether 541 individuals (56.2% women), 64.9 ± 4.2 years of age at baseline participated. Self-rated baseline PA was categorized into low, medium, or high. Cognitive function was assessed with the Mini-Mental State Examination (MMSE), executive function with the Frontal Assessment Battery (FAB), and GS (in meters/second) was measured over 2.4 m at follow-up.

Results: During a mean of 19.0 ± 1.1 years, 175 (32.3%) developed dementia. Low or medium PA compared to high PA did not associate with subsequent dementia, and PA did not associate with future cognitive function (MMSE). PA associated with executive function (FAB) (unstandardized beta [95% confidence interval]) (0.67 [0.07–1.27]), but not after adjustments. PA associated with subsequent GS in the unadjusted model and after adjustment for age, sex, smoking, and education (0.06 [0.02–0.09], and 0.04 [0.01–0.08], respectively), but not after adding adjustment for hypertension, obesity, and glucose intolerance.

Conclusion: No support was found for the hypothesis that low PA is a potential risk factor for dementia in very high age. However, PA and executive function were associated in unadjusted analyses which indicate that PA may be important for at least one aspect of cognitive function. The association between PA and GS around 2 decades later seems attenuated by cardiometabolic risk factors. Future investigations regarding PA, dementia, and cognitive decline may consider cardiometabolic risk factors such as hypertension, obesity, and glucose intolerance, and include repeated measures of PA over the life course.

Place, publisher, year, edition, pages
S. Karger, 2022
Keywords
cognitive function, dementia, executive function, gait speed, physical activity, very old people
National Category
Physiotherapy Geriatrics
Research subject
physiotherapy
Identifiers
urn:nbn:se:umu:diva-187213 (URN)10.1159/000523726 (DOI)000779096600001 ()2-s2.0-85128538079 (Scopus ID)
Funder
Forte, Swedish Research Council for Health, Working Life and Welfare, 2016-01074Swedish Research Council, K2014-99X22610-01-6The Dementia Association - The National Association for the Rights of the DementedKonung Gustaf V:s och Drottning Victorias Frimurarestiftelse
Note

Originally included in thesis in manuscript form.

Available from: 2021-09-06 Created: 2021-09-06 Last updated: 2023-05-26Bibliographically approved
Burman, M., Hörnsten, C., Öhlin, J., Olofsson, B., Nordström, P. & Gustafson, Y. (2022). Prevalence of obesity and malnutrition in four cohorts of very old adults, 2000–2017. The Journal of Nutrition, Health & Aging, 26(7), 706-713
Open this publication in new window or tab >>Prevalence of obesity and malnutrition in four cohorts of very old adults, 2000–2017
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2022 (English)In: The Journal of Nutrition, Health & Aging, ISSN 1279-7707, E-ISSN 1760-4788, Springer Link, Vol. 26, no 7, p. 706-713Article in journal (Refereed) Published
Abstract [en]

Objectives: Investigate trends in the prevalence of obesity and malnutrition among very old adults (age ≥ 85 years) between 2000 and 2017.

Design, Setting, Participants, Measurements: A study with data from the Umeå 85+/Gerontological regional database population-based cohort study of very old adults in northern Sweden. Every 5 years from 2000–2002 to 2015–2017, comprehensive assessments of participants were performed during home visits (N=1602). Body mass index (BMI) classified participants as underweight (<18.5 kg/m2), normal weight (18.5–24.9 kg/m2), overweight (25.0–29.9 kg/m2), and obese (≥30.0 kg/m2). Mini Nutritional Assessment (MNA) scores classified participants as malnourished (0 to <17), at risk of malnutrition (17–23.5), and having good nutritional status (24–30). Prevalence and trends were examined using analysis of variance and chi-squared tests, including subgroup analyses of nursing home residents.

Results: Between 2000–2002 and 2015–2017, the mean BMI increased from 24.8± 4.7 to 26.0± 4.7 kg/m2. The prevalence of obesity and underweight were 13.4% and 7.6%, respectively, in 2000–2002 and 18.3% and 3.0%, respectively, in 2015–2017. The mean MNA score increased between 2000–2002 and 2010–2012 (from 23.2± 4.7 to 24.2± 3.6), and had decreased (to 23.3± 4.2) by 2015–2017. The prevalence of malnutrition was 12.2%, 5.1%, and 8.7% in 2000–2002, 2010–2012, and 2015–2017, respectively. Subgroup analyses revealed similar BMI and MNA score patterns among nursing home residents.

Conclusions: Among very old adults, the mean BMI and prevalence of obesity seemed to increase between 2000–2002 and 2015–2017. Meanwhile, the nutritional status (according to MNA scores) seemed to improve between 2000–2002 and 2010–2012, it declined by 2015–2017.

Place, publisher, year, edition, pages
Springer, 2022
Keywords
Body mass index, malnutrition, Mini Nutritional Assessment, obesity, very old adult
National Category
Geriatrics Nursing
Identifiers
urn:nbn:se:umu:diva-182795 (URN)10.1007/s12603-022-1820-x (DOI)000824821500002 ()35842761 (PubMedID)2-s2.0-85133502496 (Scopus ID)
Funder
Swedish Research Council, K2014-99X-22610-01-6Umeå UniversityVästerbotten County Council
Note

Originally included in thesis in manuscript form. 

Available from: 2021-05-04 Created: 2021-05-04 Last updated: 2023-09-05Bibliographically approved
Hultstrand Ahlin, C., Hörnsten, C., Lilja, M., Coe, A.-B., Fjällström, P. & Hajdarevic, S. (2022). The association between sociodemographic factors and time to diagnosis for colorectal cancer in northern Sweden. European Journal of Cancer Care, 31(6), Article ID e13687.
Open this publication in new window or tab >>The association between sociodemographic factors and time to diagnosis for colorectal cancer in northern Sweden
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2022 (English)In: European Journal of Cancer Care, ISSN 0961-5423, E-ISSN 1365-2354, Vol. 31, no 6, article id e13687Article in journal (Refereed) Published
Abstract [en]

OBJECTIVES: This study examined whether sociodemographic factors, including distance to hospital, were associated with differences in the diagnostic interval and the treatment interval for colorectal cancer in northern Sweden.

METHODS: Data were retrieved from the Swedish cancer register on patients (n = 446) diagnosed in three northern regions during 2017-2018, then linked to data from Statistics Sweden and medical records. Also, Google maps was used to map the distance between patients' place of residence and nearest hospital. The different time intervals were analysed using Mann-Whitney U-test and Cox regression.

RESULTS: Differences in time to diagnosis were found between groups for income and distance to hospital, favouring those with higher income and shorter distance. The unadjusted regression analysis showed higher income to be associated with more rapid diagnosis (HR 1.004, CI 1.001-1.007). This association remained in the fully adjusted model for income (HR 1.004, CI 1.000-1.008), but not for distance. No differences between sociodemographic groups were found in the treatment interval.

CONCLUSION: Higher income and shorter distance to hospital were in the unadjusted models associated with shorter time to diagnosis for patients with CRC in northern Sweden. The association remained for income when adjusting for other variables even though the difference was small.

Place, publisher, year, edition, pages
John Wiley & Sons, 2022
Keywords
colorectal cancer, distance to hospital, socio-economic factors, time intervals, time to diagnosis
National Category
Anesthesiology and Intensive Care
Identifiers
urn:nbn:se:umu:diva-198737 (URN)10.1111/ecc.13687 (DOI)000840669900001 ()35970596 (PubMedID)2-s2.0-85135949135 (Scopus ID)
Funder
Region Västerbotten, RV-855211Region Västerbotten, RV-731891Region Västerbotten, RV-931881Cancerforskningsfonden i Norrland, LP-18-2193Visare Norr, 838121Visare Norr, 939897Kempe-Carlgrenska Foundation
Available from: 2022-08-23 Created: 2022-08-23 Last updated: 2023-05-25Bibliographically approved
Hörnsten, C., Littbrand, H., Boström, G., Rosendahl, E., Lundin-Olsson, L., Nordström, P., . . . Lövheim, H. (2021). Measurement error of the Mini-Mental State Examination among individuals with dementia that reside in nursing homes. European Journal of Ageing, 18(1), 109-115
Open this publication in new window or tab >>Measurement error of the Mini-Mental State Examination among individuals with dementia that reside in nursing homes
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2021 (English)In: European Journal of Ageing, ISSN 1613-9372, E-ISSN 1613-9380, Vol. 18, no 1, p. 109-115Article in journal (Refereed) Published
Abstract [en]

Few studies have investigated the measurement error of the Mini-Mental State Examination (MMSE) in the same unit of measurement, also known as absolute reliability. This measurement can help determine whether an observed score change for an individual is likely to represent true change. The aim of this study was to investigate the absolute reliability of the MMSE among individuals with dementia that reside in nursing homes. Among 88 participants, 19 (21.6%) were men, 35 (39.8%) had Alzheimer's disease, 35 (39.8%) had vascular dementia, and the mean age was 84.0 years (range 65-98). The participants were tested and retested with the MMSE within 1-6 days. Both tests were administered by the same assessor at the same time of day. The mean MMSE score was 13.7 (range 0-28). The absolute difference between MMSE scores varied from 0 to 6 points, and the differences did not correlate with the corresponding score means (p = 0.874). The smallest detectable change (SDC) between two measurements was 4.00. The SDC was independent of depression, impaired vision and hearing, delirium within the last week, dementia type and age. However, the SDC was 5.56 among men and 3.50 among women (p = 0.003). In conclusion, for individuals with dementia that reside in nursing homes, it seems like their MMSE score needs to change by four or more points between two measurements in order for their score change to be reliably higher than the measurement error.

Place, publisher, year, edition, pages
Springer, 2021
Keywords
Absolute reliability, Mini-Mental State Examination, Test-retest reliability, Intra-rater reliability, Dementia, Nursing homes
National Category
Geriatrics Gerontology, specialising in Medical and Health Sciences
Identifiers
urn:nbn:se:umu:diva-172500 (URN)10.1007/s10433-020-00572-9 (DOI)000537668800001 ()2-s2.0-85085951902 (Scopus ID)
Funder
Swedish Research Council, K2009-69P-21298-01-4Swedish Research Council, K2009-69X-21299-01-1Swedish Research Council, K2009-69P-21298-04-4Swedish Research Council, K2014-99X-22610-01-6Forte, Swedish Research Council for Health, Working Life and WelfareVårdal FoundationThe Dementia Association - The National Association for the Rights of the DementedSwedish Society of MedicineVästerbotten County Council
Available from: 2020-07-02 Created: 2020-07-02 Last updated: 2022-01-03Bibliographically approved
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