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Nyberg, A., Jirwe, M., Fagerdahl, A., Otten, V. T. C., Haney, M. & Olofsson, B. (2025). Perioperative patient safety indicators: a Delphi study. Journal of Clinical Nursing, 34(4), 1351-1363
Open this publication in new window or tab >>Perioperative patient safety indicators: a Delphi study
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2025 (English)In: Journal of Clinical Nursing, ISSN 0962-1067, E-ISSN 1365-2702, Vol. 34, no 4, p. 1351-1363Article in journal (Refereed) Published
Abstract [en]

Aim: To identify, define and achieve consensus on perioperative patient safety indicators within a Swedish context.

Design: A modified Delphi method.

Methods: A purposeful sample of 22 experts, all experienced operating room nurse specialists, was recruited for this study. A questionnaire was constructed incorporating statements derived from a preceding study. The experts were asked to rate the importance of each statement concerning patient safety during the perioperative phase. The data collection occurred through an online survey platform between November 2022 and April 2023. The CREDES checklist guided the reporting of this study.

Results: The three-round Delphi study resulted in consensus on 73 statements out of 103, encompassing 74% process indicators and 26% structure indicators. Key areas of consensus included the use of the Surgical Safety Checklist and optimizing the operating room environment.

Conclusion: Consensus was reached on perioperative safety indicators, underscoring the intricate challenges involved in ensuring patient safety in the operating room. It emphasizes the important integration of both structure and process indicators for comprehensive safety assessment during surgical procedures. Recognizing the difficulty in measuring factors like teamwork and communication, essential for patient safety, the study offers practical guidance. It underlines a balanced approach and specific consensus areas applicable in clinical practice to enhance perioperative patient safety.

Implications for the profession and patient care:This study provides concrete practice guidance and establishes a structured framework for evaluating perioperative care processes. It emphasizes the critical role of professionals having the necessary skills and being present during surgical procedures. Additionally, the study underscores the paramount importance of effective communication and teamwork within the operating room team, substantively contributing to overall patient safety enhancement.

Impact: The study focused on addressing the challenge of ensuring patient safety in operating rooms, acknowledging the persistent complications related to surgery despite global efforts to eliminate avoidable harm in healthcare. Consensus was reached on 73 crucial indicators for perioperative patient safety, emphasizing a balanced approach integrating both process and structure indicators for a comprehensive assessment of safety during surgical procedures. The study has a broad impact on professionals and healthcare systems, providing concrete guidance for practice and offering a structured process for evaluating perioperative care.

Reporting Method: The study is reported informed by 'Guidance on Conducting and REporting DElphi Studies (CREDES) in palliative care: Recommendations derived from a methodological systematic review'.

Patient or Public Contribution: No patient or public contribution.

Place, publisher, year, edition, pages
John Wiley & Sons, 2025
Keywords
Delphi study, operating room, patient safety, perioperative care, process register, safety indicators
National Category
Nursing
Identifiers
urn:nbn:se:umu:diva-225089 (URN)10.1111/jocn.17212 (DOI)001224563000001 ()38757741 (PubMedID)2-s2.0-85193640680 (Scopus ID)
Funder
The Kempe FoundationsUmeå University
Available from: 2024-05-27 Created: 2024-05-27 Last updated: 2025-04-14Bibliographically approved
Åkerman, S., Nyqvist, F., Nygård, M., Snellman, F. & Olofsson, B. (2025). Risk factors for loneliness among older informal caregivers in regions of Finland and Sweden: a longitudinal study. Scandinavian Journal of Public Health
Open this publication in new window or tab >>Risk factors for loneliness among older informal caregivers in regions of Finland and Sweden: a longitudinal study
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2025 (English)In: Scandinavian Journal of Public Health, ISSN 1403-4948, E-ISSN 1651-1905Article in journal (Refereed) Epub ahead of print
Abstract [en]

Aims: This longitudinal study investigated the prevalence of and risk factors for loneliness among older new informal caregivers, long-term informal caregivers, former informal caregivers and non-caregivers in selected regions of Finland and Sweden over 5 years.

Methods: A longitudinal sample of 5083 respondents from the Gerontological Regional Database (GERDA) survey data in 2016 and 2021 was used. Bivariate correlation tests and multivariate logistic regression analyses were performed.

Results: Loneliness prevalence rates varied between 6% and 8% in 2016 and increased in all groups, although not significantly among new informal caregivers. In 2021, the prevalence of loneliness varied between 8% and 14%. Among the baseline variables, reporting loneliness, single/unmarried/bereaved civil status, infrequent contact with friends and neighbours, poor self-rated health, depressive symptoms, living in Finland and financial strain increased the likelihood of reporting loneliness in 2021. Among the change variables, being a long-term caregiver, a negative change in civil status, a reduced number of confidants, a negative change in self-rated health and depressive symptoms increased the likelihood of reporting loneliness.

Conclusions: Loneliness increased among all four groups of comparison. Being a long-term caregiver was a significant risk factor for reporting loneliness over time (odds ratio 2.00, 95% confidence interval 1.20–3.35), when controlling for several other social and health-related variables. To develop effective support, future research could address risk factors for loneliness among distinct groups of informal caregivers based on whether the care recipients have neurological or functional health limitations and examine the availability of support measures.

Place, publisher, year, edition, pages
Sage Publications, 2025
Keywords
Informal care, loneliness, longitudinal, social isolation, health, risk factors, old age, Nordic, Finland, Sweden
National Category
Social Work
Research subject
Sociology
Identifiers
urn:nbn:se:umu:diva-233826 (URN)10.1177/14034948241308029 (DOI)001391524300001 ()39772875 (PubMedID)2-s2.0-85214350113 (Scopus ID)
Funder
Swedish Research Council, 014- 99X-22610-01-6Umeå UniversityRegion Västerbotten
Available from: 2025-01-09 Created: 2025-01-09 Last updated: 2025-01-24
Jonsson, F., Olofsson, B., Söderberg, S. & Niklasson, J. (2024). Association between the COVID-19 pandemic and mental health in very old people in Sweden. PLOS ONE, 19(4), Article ID e0299098.
Open this publication in new window or tab >>Association between the COVID-19 pandemic and mental health in very old people in Sweden
2024 (English)In: PLOS ONE, E-ISSN 1932-6203, Vol. 19, no 4, article id e0299098Article in journal (Refereed) Published
Abstract [en]

Background: During the COVID-19 pandemic, Sweden implemented social distancing measures to reduce infection rates. However, the recommendation meant to protect individuals particularly at risk may have had negative consequences. The aim of this study was to investigate the impact of the COVID-19 pandemic on very old Swedish peoples' mental health and factors associated with a decline in mental health.

Methods: We conducted a cross-sectional study among previous participants of the SilverMONICA (MONItoring of Trends and Determinants of CArdiovascular disease) study. Of 394 eligible participants, 257 (65.2%) agreed to participate. Of these, 250 individuals reported mental health impact from COVID-19. Structured telephone interviews were carried out during the spring of 2021. Data were analysed using the χ2 test, t-test, and binary logistic regression.

Results: Of 250 individuals (mean age: 85.5 ± 3.3 years, 54.0% women), 75 (30.0%) reported a negative impact on mental health, while 175 (70.0%) reported either a positive impact (n = 4) or no impact at all (n = 171). In the binary logistic regression model, factors associated with a decline in mental health included loneliness (odds ratio [95% confidence interval]) (3.87 [1.83-8.17]) and difficulty adhering to social distancing recommendations (5.10 [1.92-13.53]). High morale was associated with positive or no impact on mental health (0.37 [0.17-0.82]).

Conclusions: A high percentage of very old people reported a negative impact on mental health from the COVID-19 pandemic, primarily from loneliness and difficulty adhering to social distancing measures, while high morale seemed to be a protective factor.

Place, publisher, year, edition, pages
Public Library of Science (PLoS), 2024
National Category
Public Health, Global Health and Social Medicine
Identifiers
urn:nbn:se:umu:diva-223268 (URN)10.1371/journal.pone.0299098 (DOI)38564616 (PubMedID)2-s2.0-85189507899 (Scopus ID)
Funder
Umeå University
Available from: 2024-04-17 Created: 2024-04-17 Last updated: 2025-02-20Bibliographically approved
Hasselgren, L., Conradsson, M., Lampinen, J., Toots, A., Olofsson, B., Nilsson, I., . . . Littbrand, H. (2024). Feasibility of a person-centred multidimensional interdisciplinary rehabilitation programme in community-dwelling people with dementia: a randomised controlled pilot trial. BMC Geriatrics, 24(1), Article ID 794.
Open this publication in new window or tab >>Feasibility of a person-centred multidimensional interdisciplinary rehabilitation programme in community-dwelling people with dementia: a randomised controlled pilot trial
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2024 (English)In: BMC Geriatrics, E-ISSN 1471-2318, Vol. 24, no 1, article id 794Article in journal (Refereed) Published
Abstract [en]

Background: A team-based, individualised rehabilitation approach may be required to meet the complex needs of people with dementia. This randomised controlled pilot trial evaluated the feasibility of a person-centred multidimensional interdisciplinary rehabilitation programme for community-dwelling older people with dementia and their informal primary caregivers.

Methods: Participants with dementia were randomised to an intervention group (n = 31, mean age (SD) 78.4 (6.0) years) or usual care (n = 30, mean age 79.0 (7.1)). The rehabilitation programme consisted of a 20-week rehabilitation period containing assessments and interventions based on each individual’s goals, and group-based physical exercise plus social interaction twice a week for 16 weeks at a rehabilitation unit. After 5 and 14 months, the interdisciplinary team followed up participants over two four-week periods. For both groups, dates of deaths and decision to move to nursing home over three years, as well as interventions for the relevant periods, were collected. Blinded assessors measured physical functions, physical activity, activities of daily living, cognitive functions, nutritional status, and neuropsychiatric symptoms at baseline and at 5, 12, 24, and 36 months.

Results: Participants in the intervention group received a mean of 70.7 (20.1) interventions during the 20-week rehabilitation period, delivered by all ten team professions. The corresponding figures for the control group were 5.8 (5.9). In the intervention group, all but one participated in rehabilitation planning, including goal setting, and attendance in the exercise and social interaction groups was 74.8%. None of the adverse events (n = 19) led to any manifest injury or disease. Cox proportional hazard regression showed a non-significant lower relative risk (HR = 0.620, 95% CI 0.27–1.44) in favour of the intervention for moving to nursing home or mortality during the 36-month follow-up period. Linear mixed-effect models showed non-significant but potentially clinically meaningful between-group differences in gait, physical activity, and neuropsychological symptoms in favour of the intervention.

Conclusions: The rehabilitation programme seems feasible among community-dwelling older people with dementia. The overall results merit proceeding to a future definitive randomised controlled trial, exploring effects and cost-effectiveness. One could consider to conduct the programme earlier in the course of dementia, adding cognitive training and a control attention activity.

Trial registration: The study protocol, ISRCTN59155421, was registered online 4/11/2015.

Place, publisher, year, edition, pages
BioMed Central (BMC), 2024
Keywords
Community-dwelling, Dementia, Feasibility study, Interdisciplinary, Rehabilitation
National Category
Geriatrics
Identifiers
urn:nbn:se:umu:diva-230590 (URN)10.1186/s12877-024-05372-9 (DOI)39342131 (PubMedID)2-s2.0-85205336926 (Scopus ID)
Funder
Forte, Swedish Research Council for Health, Working Life and Welfare, 2014−0897Promobilia foundationThe Dementia Association - The National Association for the Rights of the DementedThe Janne Elgqvist Family FoundationRegion VästerbottenAlzheimerfondenFoundation for the Memory of Ragnhild and Einar LundströmStiftelsen Gamla Tjänarinnor
Available from: 2024-10-08 Created: 2024-10-08 Last updated: 2024-10-08Bibliographically approved
Bergfrid, M., Gustafson, Y., Littbrand, H., Olofsson, B. & Weidung, B. (2024). Having plans for the future in very old people. The International Journal of Aging & Human Development, 99(3), 373-394
Open this publication in new window or tab >>Having plans for the future in very old people
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2024 (English)In: The International Journal of Aging & Human Development, ISSN 0091-4150, E-ISSN 1541-3535, Vol. 99, no 3, p. 373-394Article in journal (Refereed) Published
Abstract [en]

This study aimed to investigate the prevalence of having plans for the future among very old people and the factors associated with having such plans. A longitudinal population-based study with home visits for 85-, 90-, and ≥95-year-old participants in Sweden and Finland was used. Multivariate logistic regression and Cox proportional-hazards regression models with a maximum 5-year follow-up period were used. The prevalence of having plans for the future was 18.6% (174/936). More men than women and more people living in Sweden than in Finland had plans for the future. In multivariate models, having plans for the future was associated with speaking Swedish, being dentate, and living in the community in the total sample; speaking Swedish and being dentate among women; and speaking Swedish, having a lower Geriatric Depression Scale score, and urban residence among men. Having plans for the future was associated univariately, but not multivariately, with increased survival.

Place, publisher, year, edition, pages
Sage Publications, 2024
Keywords
aged 80 and over, future perception, gerontology, optimism, plans for the future, survival
National Category
Gerontology, specialising in Medical and Health Sciences Nursing
Identifiers
urn:nbn:se:umu:diva-221560 (URN)10.1177/00914150241231189 (DOI)001159569300001 ()38342991 (PubMedID)2-s2.0-85185275774 (Scopus ID)
Funder
Umeå UniversityThe Dementia Association - The National Association for the Rights of the DementedSwedish Research Council, K2014-99X-22610-01-6Visare NorrRegion VästerbottenKonung Gustaf V:s och Drottning Victorias Frimurarestiftelse
Available from: 2024-03-05 Created: 2024-03-05 Last updated: 2024-10-28Bibliographically approved
Nyberg, A., Olofsson, B., Fagerdahl, A., Haney, M. & Otten, V. T. (2024). Longer work experience and age associated with safety attitudes in operating room nurses: an online cross-sectional study. BMJ open quality, 13(1), Article ID bmjoq-2022-002182.
Open this publication in new window or tab >>Longer work experience and age associated with safety attitudes in operating room nurses: an online cross-sectional study
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2024 (English)In: BMJ open quality, E-ISSN 2399-6641, Vol. 13, no 1, article id bmjoq-2022-002182Article in journal (Refereed) Published
Abstract [en]

BACKGROUND: Patient safety is fundamental when providing care in the operating room. Still, adverse events and errors are a challenge for patient safety worldwide. To avoid preventable patient harm, organisations need a positive safety culture, the measurable component of which is known as the safety climate. To best improve the safety climate the current attitudes to safety must first be understood.

AIM: To explore operating room nurses' safety attitudes and their views on how to improve patient safety in operating rooms.

ETHOD: A cross-sectional study using the Swedish-translated version of the Safety Attitudes Questionnaire, Operating Room version. Data were collected using an online survey platform.

RESULTS: 358 operating room nurses completed the questionnaire. The results show that the older age group rated their working conditions and management support as better than the younger age groups. The older age group also rated their stress recognition as lower compared with the younger age groups. The same pattern was seen in terms of work experience, with more-experienced respondents showing a higher mean score for the factor working conditions and a lower mean score for the factor stress recognition as compared with their less-experienced colleagues. When comparing hospital types, county hospital employees had higher factor scores for safety climate, job satisfaction and working conditions than university hospital employees. The respondents' most recurring recommendations for improving patient safety were 'Having better and clearer communication' followed by 'Having enough time to do things the way they should be done'.

CONCLUSION: More focus on safety with increasing age and experience was observed in this cohort. Need for improvements is reported for patient safety in operating rooms, mainly when it comes to communication and workload. To improve and develop patient safety in the operating room, the organisational safety climate needs to be actively managed and developed. One step in actively managing the safety climate may be efforts to retain experienced operating room nurses.

Place, publisher, year, edition, pages
BMJ Publishing Group Ltd, 2024
Keywords
Attitudes, Nurses, Patient safety, Safety culture, Surgery
National Category
Nursing
Identifiers
urn:nbn:se:umu:diva-219813 (URN)10.1136/bmjoq-2022-002182 (DOI)38212132 (PubMedID)2-s2.0-85182094382 (Scopus ID)
Funder
The Kempe FoundationsUmeå University
Available from: 2024-01-23 Created: 2024-01-23 Last updated: 2024-09-23Bibliographically approved
Corneliusson, L., Gustafson, Y. & Olofsson, B. (2024). Prevalence of depressive disorders among the very old in the 21st century. Journal of Affective Disorders, 362, 706-715
Open this publication in new window or tab >>Prevalence of depressive disorders among the very old in the 21st century
2024 (English)In: Journal of Affective Disorders, ISSN 0165-0327, E-ISSN 1573-2517, Vol. 362, p. 706-715Article in journal (Refereed) Published
Abstract [en]

Background: The aim of this study is to explore the prevalence of depressive disorders in very old adults over time, in rural/urban environments, between men/women, as well as to explore other factors associated with depressive disorders.

Methods: This study was conducted utilizing the GERDA-database data, which consists of four cohorts of 85, 90 and 95+ year olds living in Northern Sweden. Participants could reside independently or in residential care. Data collections took place between 2000 and 2017. Descriptive data and logistic regression models were utilized to explore data.

Results: The prevalence of depressive disorders increased between 2000/02 and 2015/17 in all age groups, with the highest percentages observed in the 95+ age group, reaching 53.6 % in 2015/17. The prevalence varied from 20.3 % in those without dementia to 65.1 % in those with dementia. Sex or living in an urban/rural environment was not associated with an increased risk of depression in the fully adjusted models. Dementia and reduced capacity in activities of daily living were associated with depressive disorders among 85 and 90-year-olds, while living alone was associated with depressive disorders in the 95+ age group.

Limitations: Potentially limited generalizability, as this study took place in northern Sweden.

Conclusions: The prevalence of depressive disorders among very old adults increases with age and the prevalence also increases throughout cohorts and time. These alarming rates of depressive disorders among the very old require immediate measures and further investigation. Future studies are needed to explore and monitor trends and to plan and design tailored interventions.

Place, publisher, year, edition, pages
Elsevier, 2024
Keywords
Depressive disorder, Epidemiology, Oldest old, Rural health, Sex differences, Urban health
National Category
Psychiatry Public Health, Global Health and Social Medicine Geriatrics
Identifiers
urn:nbn:se:umu:diva-228033 (URN)10.1016/j.jad.2024.07.062 (DOI)39029671 (PubMedID)2-s2.0-85198954651 (Scopus ID)
Funder
Swedish Research Council, K2014–99X-22610–01–6Region VästerbottenThe Dementia Association - The National Association for the Rights of the DementedEU, European Research CouncilEuropean Regional Development Fund (ERDF)Interreg
Available from: 2024-07-25 Created: 2024-07-25 Last updated: 2025-02-20Bibliographically approved
Svahn, S., Appelblad, L., Lövheim, H., Gustafson, Y., Olofsson, B. & Gustafsson, M. (2024). Prevalence of heart failure and trends in its pharmacological treatment between 2000 and 2017 among very old people. BMC Geriatrics, 24(1), Article ID 701.
Open this publication in new window or tab >>Prevalence of heart failure and trends in its pharmacological treatment between 2000 and 2017 among very old people
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2024 (English)In: BMC Geriatrics, E-ISSN 1471-2318, Vol. 24, no 1, article id 701Article in journal (Refereed) Published
Abstract [en]

Purpose: The aim of this study was to describe a population of very old people with heart failure (HF), to analyse the use of cardiovascular drugs over time, and to explore factors influencing cardiovascular drug treatment for this group.

Methods: All participants with information regarding HF diagnosis were selected from the Umeå 85+/Gerontological Regional Database (GERDA). The people in GERDA are all ≥85 years old. Trained investigators performed structured interviews and assessments. Information regarding medications and diagnoses was obtained from the participants and from medical records. Medical diagnoses were reviewed and confirmed by an experienced geriatrician.

Results: In this very old population, the prevalence of HF was 29.6% among women and 30.7% among men. Between 2000 and 2017, there was an increase in the use of renin-angiotensin (RAS) inhibitors (odds ratio [OR] 1.107, 95% confidence interval [CI] 1.072–1.144) and beta-blockers (BBs) (OR 1.123, 95% CI 1.086–1.161) among persons with HF, whereas the prevalence of loop diuretics (OR 0.899, 95% CI 0.868–0.931) and digitalis (OR 0.864, 95% CI 0.828–0.901) decreased (p < 0.001 for all drug classes). Higher age was associated with lower use of RAS inhibitors and BBs.

Conclusion: In this HF population, the use of evidence-based medications for HF increased over time. This may be a sign of better awareness among prescribers regarding the under-prescribing of guidelines-recommended treatment to old people. Higher age associated with a lower prevalence of RAS inhibitors and BBs. This might indicate that further improvement is possible but could also represent a more cautious prescribing among frail very old individuals.

Place, publisher, year, edition, pages
Springer Nature, 2024
Keywords
Cardiovascular drugs, Drug use, Heart failure, Very old people
National Category
Geriatrics Cardiology and Cardiovascular Disease
Identifiers
urn:nbn:se:umu:diva-229385 (URN)10.1186/s12877-024-05307-4 (DOI)001297617900008 ()39182036 (PubMedID)2-s2.0-85201929935 (Scopus ID)
Funder
Swedish Research Council, K2014–99X-22610–01–6The Dementia Association - The National Association for the Rights of the DementedInterreg
Available from: 2024-09-12 Created: 2024-09-12 Last updated: 2025-02-10Bibliographically approved
Almevall, A., Dahlin Almevall, A., Öhlin, J., Gustafson, Y., Zingmark, K., Niklasson, J., . . . Olofsson, B. (2024). Self-rated health in old age, related factors and survival: A 20-Year longitudinal study within the Silver-MONICA cohort. Archives of gerontology and geriatrics (Print), 122, Article ID 105392.
Open this publication in new window or tab >>Self-rated health in old age, related factors and survival: A 20-Year longitudinal study within the Silver-MONICA cohort
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2024 (English)In: Archives of gerontology and geriatrics (Print), ISSN 0167-4943, E-ISSN 1872-6976, Vol. 122, article id 105392Article in journal (Refereed) Published
Abstract [en]

Introduction: Self-rated health (SRH) offers insights into the evolving health demographics of an ageing population.

Aim: To assess change in SRH from old age to very old age and their associations with health and well-being factors, and to investigate the association between SRH and survival.

Methods: All participants in the MONICA 1999 re-examination born before 1940 (n = 1595) were included in the Silver-MONICA baseline cohort. The Silver-MONICA follow-up started in 2016 included participants in the Silver-MONICA baseline cohort aged 80 years or older. Data on SRH was available for 1561 participants at baseline with 446 of them also participating in the follow-up. The follow-up examination included a wide variety of measurements and tests.

Findings: Most participants rated their health as "Quite good" (54.5 %) at baseline. Over the study period, 42.6 % had stable SRH, 40.6 % had declined, and 16.8 % had improved. Changes in SRH were at follow-up significantly associated with age, pain, nutrition, cognition, walking aid use, self-paced gait speed, lower extremity strength, independence in activities of daily living, weekly physical exercise, outdoor activity, participation in organized activities, visiting others, morale, and depressive symptoms. SRH at baseline was significantly associated with survival (p < 0.05).

Conclusion: This study demonstrates associations between changes in SRH and a multitude of health- and wellbeing-related factors, as well as a relation between survival and SRH, accentuating their relevance within the ageing population.

Place, publisher, year, edition, pages
Elsevier, 2024
Keywords
Aged 80 and over, Aging/psychology, Diagnostic self evaluation, Longitudinal studies, Population characteristics, Self-rated health, Survival analysis
National Category
Public Health, Global Health and Social Medicine
Identifiers
urn:nbn:se:umu:diva-222682 (URN)10.1016/j.archger.2024.105392 (DOI)38492492 (PubMedID)2-s2.0-85187986768 (Scopus ID)
Funder
Forte, Swedish Research Council for Health, Working Life and Welfare, 2016-01074Swedish Research Council, K2014-99X-22610-01-6Visare NorrNorrbotten County CouncilRegion VästerbottenSwedish Dementia CentreFoundation for the Memory of Ragnhild and Einar LundströmSwedish Society of MedicineKonung Gustaf V:s och Drottning Victorias Frimurarestiftelse
Available from: 2024-04-09 Created: 2024-04-09 Last updated: 2025-02-20Bibliographically approved
Corneliusson, L., Öhlin, J., Toots, A., Gustafson, Y. & Olofsson, B. (2024). The association between gait speed and depressive disorders: A cross-sectional analysis of very old adults in the 21st century. Aging & Mental Health
Open this publication in new window or tab >>The association between gait speed and depressive disorders: A cross-sectional analysis of very old adults in the 21st century
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2024 (English)In: Aging & Mental Health, ISSN 1360-7863, E-ISSN 1364-6915Article in journal (Refereed) Epub ahead of print
Abstract [en]

Objectives: To investigate the association between gait speed and depressive disorders among very old adults (≥85 years).

Method: This study utilized the GERDA-database, which encompasses a representative sample of those aged 85, 90, and 95+ years residing in northern Sweden and western Finland. From four data collections between 2000 and 2017, this study included 1794 participants. Self-paced gait speed was measured over 2.4-m and depressive disorders was evaluated by a specialist in geriatric medicine according to the DSM-IV-TR criteria. T-tests and multivariable logistic regressions were used to explore differences and associations between gait speed and depressive disorders.

Results: Gait speed was independently associated with depressive disorders among very old adults (p <.001). The results showed significantly different mean gait speeds (m/s) between individuals with/without a depressive disorder (0.34 ± 0.24/0.52 ± 0.26, p <.001), between individuals with a depressive disorder with/without antidepressant treatment (0.35 ± 0.24/0.44 ± 0.24, p <.001) and between non-responders/responders to antidepressants (0.36 ± 0.21/0.42 ± 0.22, p =.020).

Conclusion: This is the first study focusing on very old adults that has shown an independent association between gait speed and depressive disorders. Responders to antidepressant medication had a higher mean gait speed than non-responders, which may imply shifts in function upon successful treatment.

Place, publisher, year, edition, pages
Routledge, 2024
Keywords
antidepressants, depressive disorders, Gait speed, oldest old
National Category
Geriatrics
Identifiers
urn:nbn:se:umu:diva-233324 (URN)10.1080/13607863.2024.2436479 (DOI)001374443900001 ()39648653 (PubMedID)2-s2.0-85211210948 (Scopus ID)
Funder
Swedish Research Council, K2014–99X-22610–01–6Umeå UniversityVästerbotten County Council
Available from: 2025-01-02 Created: 2025-01-02 Last updated: 2025-01-02
Organisations
Identifiers
ORCID iD: ORCID iD iconorcid.org/0000-0002-3754-5026

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