Umeå University's logo

umu.sePublications
Change search
Link to record
Permanent link

Direct link
Publications (10 of 35) Show all publications
Frykholm, E., Simonsson, E., Levik Sandström, S., Hedlund, M., Holmberg, H., Johansson, B., . . . Rosendahl, E. (2024). Applicability of a supramaximal high-intensity interval training program for older adults previously not engaged in regular exercise: analyses of secondary outcomes from the Umeå HIT Study. Psychology of Sport And Exercise, 73, Article ID 102647.
Open this publication in new window or tab >>Applicability of a supramaximal high-intensity interval training program for older adults previously not engaged in regular exercise: analyses of secondary outcomes from the Umeå HIT Study
Show others...
2024 (English)In: Psychology of Sport And Exercise, ISSN 1469-0292, E-ISSN 1878-5476, Vol. 73, article id 102647Article in journal (Refereed) Published
Abstract [en]

This analysis of secondary outcomes investigated the applicability of supramaximal high-intensity interval training (HIT) with individually prescribed external intensity performed on stationary bicycles. Sixty-eight participants with a median (min; max) age of 69 (66; 79), at the time not engaged in regular exercise were randomized to 25 twice-weekly sessions of supramaximal HIT (20-min session with 10 × 6-s intervals) or moderate-intensity training (MIT, 40-min session with 3 × 8-min intervals). The primary aim was outcomes on applicability regarding; adherence to prescribed external interval intensity, participant reported positive and negative events, ratings of perceived exertion (RPE 6–20), and affective state (Feeling Scale, FS -5–5). A secondary aim was to investigate change in exercise-related self-efficacy (Exercise Self-Efficacy Scale) and motivation (Behavioural Regulations in Exercise Questionnaire-2). Total adherence to the prescribed external interval intensity was [median (min; max)] 89 % (56; 100 %) in supramaximal HIT, and 100 % (95; 100 %) in MIT. The supramaximal HIT group reported 60 % of the positive (112 of 186) and 36 % of the negative (52 of 146) events. At the end of the training period, the median (min; max) session RPE was 15 (12; 17) for supramaximal HIT and 14 (9; 15) for MIT. As for FS, the median last within-session rating was 3 (−1; 5) for supramaximal HIT and 3 (1; 5) for MIT. Exercise-related motivation increased (mean difference in Relative Autonomy Index score = 1.54, 95 % CI [0.69; 2.40]), while self-efficacy did not change (mean difference = 0.55, 95 % CI [-0.75; 1.82]), regardless of group. This study provide support for supramaximal HIT in supervised group settings for older adults.

Place, publisher, year, edition, pages
Elsevier, 2024
Keywords
Feasibility, HIIT, Randomized controlled trial, SIT, Sprint interval training
National Category
Sport and Fitness Sciences
Identifiers
urn:nbn:se:umu:diva-223607 (URN)10.1016/j.psychsport.2024.102647 (DOI)38604572 (PubMedID)2-s2.0-85190305065 (Scopus ID)
Funder
Swedish Research Council, 2017–00912Forte, Swedish Research Council for Health, Working Life and Welfare, 2020–00159The Kamprad Family FoundationThe Dementia Association - The National Association for the Rights of the DementedFoundation for the Memory of Ragnhild and Einar LundströmThe Kempe Foundations
Available from: 2024-05-02 Created: 2024-05-02 Last updated: 2024-05-02Bibliographically approved
Holmberg, H., Glader, E.-L., Näslund, U., Carlberg, B., Sönnerstam, E., Norberg, M. & Själander, A. (2024). Improved adherence to statin treatment and differences in results between men and women after pictorial risk communication: a sub-study of the VIPVIZA RCT. European Journal of Clinical Pharmacology
Open this publication in new window or tab >>Improved adherence to statin treatment and differences in results between men and women after pictorial risk communication: a sub-study of the VIPVIZA RCT
Show others...
2024 (English)In: European Journal of Clinical Pharmacology, ISSN 0031-6970, E-ISSN 1432-1041Article in journal (Refereed) Epub ahead of print
Abstract [en]

Background: People with intermediate CVD risk constitute most of the population. Within this group, the proportion of events is lower compared to the high-risk group, but they contribute with the largest absolute number of events. Atherosclerosis is a dynamic process and progression can be slowed or even reversed with medication and lifestyle changes, but adherence to prescribed treatment is crucial.

Aim: To investigate the long-term effects of interventions with pictorial risk communication of cardiovascular (CVD) risk on average adherence in a group of statin users. Compare response in adherence over time between men and women after intervention.

Methods: Participants on active statin treatment were followed up to 5 years after being randomly assigned to an intervention program aimed at raising CVD risk awareness among participants and their physicians. Merging prescribed medication databases with VIPVIZA study to study adherence over time. A moving average adherence was used to compare groups.

Results: Generally, the average adherence to statins among the 512 participants was high. Men had a higher average adherence over time, while women had a sharper increase in adherence in conjuncture with the intervention program.

Conclusions: Both men and women were receptive to pictorial information regarding CVD risk, but the intervention effect was more pronounced in women. Sex differences are important when considering risk communication strategies. Periodically repeating the intervention was beneficial for maintaining the intervention effect over time.

Trial registration: The VIPVIZA study is registered with ClinicalTrials.gov, May 8, 2013, number NCT01849575.

Place, publisher, year, edition, pages
Springer, 2024
Keywords
Atherosclerosis, Cardiovascular disease prevention, Cardiovascular risk, Pictorial information, Statin initiation, Statins
National Category
Public Health, Global Health, Social Medicine and Epidemiology Cardiac and Cardiovascular Systems
Identifiers
urn:nbn:se:umu:diva-224129 (URN)10.1007/s00228-024-03694-6 (DOI)001209527900001 ()38684558 (PubMedID)2-s2.0-85191700644 (Scopus ID)
Funder
Region Västerbotten, ALFVLL-298001Region Västerbotten, ALFVLL-643391Swedish Research Council, 521-2013-2708Swedish Research Council, 2016-01891Swedish Heart Lung Foundation, 20150369Swedish Heart Lung Foundation, 20170481Swedish Society of MedicineNorrländska HjärtfondenThe Swedish Stroke AssociationSwedish Social Insurance AgencyVisare NorrThe Swedish Heart and Lung Association
Available from: 2024-05-14 Created: 2024-05-14 Last updated: 2024-05-14
Hemberg, A., Landén, J., Montgomery, A., Holmberg, H. & Nordin, P. (2024). Management of groin hernia repair in Sweden: a register-based comparative analysis of public and private healthcare providers. Scandinavian Journal of Surgery
Open this publication in new window or tab >>Management of groin hernia repair in Sweden: a register-based comparative analysis of public and private healthcare providers
Show others...
2024 (English)In: Scandinavian Journal of Surgery, ISSN 1457-4969, E-ISSN 1799-7267Article in journal (Refereed) Epub ahead of print
Abstract [en]

Background: Swedish healthcare is in a period of transition with an expanding private sector. This study compares quality of outcome after groin hernia repair performed in a public or private healthcare setting.

Methods: A cohort study based on data from the Swedish National Hernia Register combined with Patient-Reported Outcome Measures (PROMs) 1 year after groin hernia repair. Between September 2012 and December 2018, a questionnaire was sent to all patients registered in the hernia register 1 year after surgery. Endpoints were reoperation for recurrence, chronic pain, and patient satisfaction.

Results: From a total of 87,650 patients with unilateral groin hernia repair, 61,337 PROM answers (70%) were received from 71 public and 28 private healthcare providers. More females, acute and recurrent cases, and patients with high American Society of Anesthesiology (ASA) scores were operated under the national healthcare system. The private sector had more experience surgeons with higher annual volume per surgeon, shorter time on waiting lists, and shorter operation times. No difference was seen in patient satisfaction. Groin hernia repair performed in a private clinic was associated with less postoperative chronic pain (OR 0.85, 95% CI 0.8–0.91) but a higher recurrence rate (HR 1.41; 95% CI 1.26–1.59) in a multivariable logistic regression analysis.

Conclusion: Despite private clinics having a higher proportion of experienced surgeons and fewer complex cases, the recurrence rate was higher, whereas the risk for chronic postoperative pain was higher among patients treated in the public sector.

Place, publisher, year, edition, pages
Sage Publications, 2024
Keywords
chronic pain, Groin hernia repair, patient satisfaction, public and private healthcare, reoperation for recurrence
National Category
Surgery
Identifiers
urn:nbn:se:umu:diva-223629 (URN)10.1177/14574969241242312 (DOI)001198809800001 ()2-s2.0-85190448909 (Scopus ID)
Available from: 2024-04-25 Created: 2024-04-25 Last updated: 2024-04-25
Enblom-Larsson, A., Renlund, H., Andréasson, B., Holmberg, H., Liljeholm, M. & Själander, A. (2024). Thromboembolic events, major bleeding and mortality in essential thrombocythaemia and polycythaemia vera: a matched nationwide population-based study. British Journal of Haematology
Open this publication in new window or tab >>Thromboembolic events, major bleeding and mortality in essential thrombocythaemia and polycythaemia vera: a matched nationwide population-based study
Show others...
2024 (English)In: British Journal of Haematology, ISSN 0007-1048, E-ISSN 1365-2141Article in journal (Refereed) Epub ahead of print
Abstract [en]

Thromboembolic events and bleeding are known complications in essential thrombocythaemia (ET) and polycythaemia vera (PV). Using multiple Swedish health care registers, we assessed the rate of arterial and venous events, major bleeding, all-cause stroke and all-cause mortality in ET and PV compared to matched controls. For each patient with ET (n = 3141) and PV (n = 2604), five matched controls were randomly selected. In total, 327 and 405 arterial or venous events were seen in the group of ET and PV patients respectively. Compared to corresponding controls, the rate of venous thromboembolism, major bleeding and all-cause mortality per 100 treatment years was significantly increased among both ET (0.63, 0.79 and 3.70) and PV patients (0.94, 1.20 and 4.80). The PV patients also displayed a significantly higher rate of arterial events and all-cause stroke compared to controls. When dividing the cohort into age groups, we found a significantly higher rate of arterial and venous events in all age groups of PV patients, and the rate of all-cause mortality was significantly higher in both ET and PV patients in all ages above the age of 50. This study confirms that PV and ET are diseases truly marked by thromboembolic complications and bleeding.

Place, publisher, year, edition, pages
John Wiley & Sons, 2024
Keywords
essential thrombocythaemia, polycythaemia vera, thrombosis (venous), thrombosis - arterial
National Category
Hematology Cardiac and Cardiovascular Systems
Identifiers
urn:nbn:se:umu:diva-221663 (URN)10.1111/bjh.19337 (DOI)38351734 (PubMedID)2-s2.0-85185487280 (Scopus ID)
Funder
The Swedish Stroke AssociationVisare Norr
Available from: 2024-03-04 Created: 2024-03-04 Last updated: 2024-03-04
Axman, E., Holmberg, H., Rutegård, M. & De La Croix, H. (2023). Association between previous inguinal hernia surgery and the risk of anastomotic leakage after colorectal surgery: nationwide registry-based study. BJS Open, 7(4), Article ID zrad076.
Open this publication in new window or tab >>Association between previous inguinal hernia surgery and the risk of anastomotic leakage after colorectal surgery: nationwide registry-based study
2023 (English)In: BJS Open, E-ISSN 2474-9842, Vol. 7, no 4, article id zrad076Article in journal (Refereed) Published
Place, publisher, year, edition, pages
Oxford University Press, 2023
National Category
Surgery
Identifiers
urn:nbn:se:umu:diva-215115 (URN)10.1093/bjsopen/zrad076 (DOI)001059215100001 ()37650245 (PubMedID)2-s2.0-85172005589 (Scopus ID)
Funder
Knut and Alice Wallenberg FoundationSwedish Society of Medicine, SLS-973834
Available from: 2023-10-20 Created: 2023-10-20 Last updated: 2024-02-01Bibliographically approved
Welander, F., Renlund, H., Dimény, E., Holmberg, H. & Själander, A. (2023). Direct oral anticoagulants versus warfarin in patients with non-valvular atrial fibrillation and CKD G3-G5D. Clinical Kidney Journal, 16(5), 835-844
Open this publication in new window or tab >>Direct oral anticoagulants versus warfarin in patients with non-valvular atrial fibrillation and CKD G3-G5D
Show others...
2023 (English)In: Clinical Kidney Journal, ISSN 2048-8505, E-ISSN 2048-8513, Vol. 16, no 5, p. 835-844Article in journal (Refereed) Published
Abstract [en]

Background: The use of direct oral anticoagulants (DOAC) in patients with non-valvular atrial fibrillation (NVAF) and advanced chronic kidney disease (CKD) including dialysis is growing. Several studies have shown favorable results of DOAC compared with warfarin regarding bleeding risk but no difference in stroke protection. However, these studies had poor time in therapeutic range (TTR), in the warfarin comparison group.

Methods: This was a Swedish national cohort study investigating the risk of ischemic stroke and major bleeding on DOAC compared with warfarin in patients with NVAF, glomerular filtration rate category 3-5D (G3-G5D), kidney transplant recipients excluded, between 2009 and 2018. Data extracted from high-quality national healthcare registries including the Swedish Renal Registry, AuriculA (the Swedish national quality register for AF and anticoagulation) and The Stroke Register.

Results: At enrolment, of 2453 patients 59% were treated with warfarin (mean TTR 67%) and 41% with DOAC. Overall, 693 (28.3%) had G3, 1113 (45.4%) G4, 222 (9.1%) G5 and 425 (17.3%) G5D. DOAC compared with warfarin showed lower hazard of major bleeding [hazard ratio 0.71 (95% confidence interval 0.53-0.96)] but no difference in ischemic stroke risk. Mortality was increased during DOAC treatment [1.24 (1.01-1.53)], presumably not a causal association since fewer fatal bleedings occurred on DOAC.

Conclusions: DOAC treatment, compared with warfarin, is associated with almost 30% lower risk of bleeding in patients with NVAF and CKD G3-G5D. The stroke risk is comparable between the treatments. This is the first study comparing DOAC and well-managed warfarin (TTR 67%) in advanced CKD. Ongoing and planned randomized controlled trials need to confirm the possible benefit of DOAC.

Place, publisher, year, edition, pages
Oxford University Press, 2023
Keywords
anticoagulants, atrial fibrillation, chronic kidney disease, dialysis
National Category
Cardiac and Cardiovascular Systems Urology and Nephrology
Identifiers
urn:nbn:se:umu:diva-214743 (URN)10.1093/ckj/sfad004 (DOI)000942734700001 ()37151425 (PubMedID)2-s2.0-85171785255 (Scopus ID)
Funder
Region Västernorrland, LVNFOU938547The Swedish Stroke AssociationThe Swedish Kidney Foundation, F2022-0084The Swedish Kidney Foundation, F2021-0105Swedish Heart Lung Foundation, 20200766
Available from: 2023-10-02 Created: 2023-10-02 Last updated: 2023-11-05Bibliographically approved
Simonsson, E., Levik Sandström, S., Hedlund, M., Holmberg, H., Johansson, B., Lindelöf, N., . . . Rosendahl, E. (2023). Effects of controlled supramaximal high-intensity interval training on cardiorespiratory fitness and global cognitive function in older adults: the Umeå hit study-a randomized controlled trial. The journals of gerontology. Series A, Biological sciences and medical sciences, 78(9), 1581-1590
Open this publication in new window or tab >>Effects of controlled supramaximal high-intensity interval training on cardiorespiratory fitness and global cognitive function in older adults: the Umeå hit study-a randomized controlled trial
Show others...
2023 (English)In: The journals of gerontology. Series A, Biological sciences and medical sciences, ISSN 1079-5006, E-ISSN 1758-535X, Vol. 78, no 9, p. 1581-1590Article in journal (Refereed) Published
Abstract [en]

BACKGROUND: This study examined the effects of regulated and controlled supramaximal high-intensity interval training (HIT) adapted for older adults, compared to moderate-intensity training (MIT), on cardiorespiratory fitness; cognitive, cardiovascular, and muscular function; and quality of life.

METHODS: Sixty-eight nonexercising older adults (66-79 years, 44% males) were randomized to 3 months of twice-weekly HIT (20-minute session including 10 × 6-second intervals) or MIT (40-minute session including 3 × 8-minute intervals) on stationary bicycles in an ordinary gym setting. Individualized target intensity was watt controlled with a standardized pedaling cadence and individual adjustment of the resistance load. Primary outcomes were cardiorespiratory fitness (V̇o2peak) and global cognitive function (unit-weighted composite).

RESULTS: V̇o2peak increased significantly (mean 1.38 mL/kg/min, 95% CI [0.77, 1.98]), with no between-group difference (mean difference 0.05 [-1.17, 1.25]). Global cognition did not improve (0.02 [-0.05, 0.09]), nor differed between groups (0.11 [-0.03, 0.24]). Significant between-group differences in change were observed for working memory (0.32 [0.01, 0.64]), and maximal isometric knee extensor muscle strength (0.07 N·m/kg [0.003, 0.137]), both in favor of HIT. Irrespective of the group, there was a negative change in episodic memory (-0.15 [-0.28, -0.02]), a positive change in visuospatial ability (0.26 [0.08, 0.44]), and a decrease in systolic (-2.09 mmHg [-3.54, -0.64]) and diastolic (-1.27 mmHg [-2.31, -0.25]) blood pressure.

CONCLUSIONS: In nonexercising older adults, 3 months of watt-controlled supramaximal HIT improved cardiorespiratory fitness and cardiovascular function to a similar extent as MIT, despite half the training time. In favor of HIT, there was an improvement in muscular function and a potential domain-specific effect on working memory.

CLINICAL TRIAL REGISTRATION: NCT03765385.

Place, publisher, year, edition, pages
Oxford University Press, 2023
Keywords
Aerobic capacity, HIIT, Moderate-intensity training, SIT, Sprint interval training
National Category
Sport and Fitness Sciences
Identifiers
urn:nbn:se:umu:diva-214207 (URN)10.1093/gerona/glad070 (DOI)000959356800001 ()36972981 (PubMedID)2-s2.0-85169177109 (Scopus ID)
Funder
Swedish Research Council, 2017-00912Forte, Swedish Research Council for Health, Working Life and Welfare, 2020-00159The Kamprad Family FoundationThe Dementia Association - The National Association for the Rights of the DementedFoundation for the Memory of Ragnhild and Einar LundströmThe Kempe FoundationsUmeå University
Available from: 2023-09-08 Created: 2023-09-08 Last updated: 2023-09-08Bibliographically approved
Enblom, A., Andréasson, B., Holmberg, H., Liljeholm, M. & Själander, A. (2023). Erythrocytosis, thrombocytosis, and rate of recurrent thromboembolic event: a population based cohort study. European Journal of Haematology, 110(6), 608-617
Open this publication in new window or tab >>Erythrocytosis, thrombocytosis, and rate of recurrent thromboembolic event: a population based cohort study
Show others...
2023 (English)In: European Journal of Haematology, ISSN 0902-4441, E-ISSN 1600-0609, Vol. 110, no 6, p. 608-617Article in journal (Refereed) Published
Abstract [en]

Introduction: The management to reduce risk of thromboembolic complications in polycythemia vera and essential thrombocythemia are well established, but for other conditions with elevated hemoglobin, hematocrit, or platelets there are no consensus regarding treatment and follow up.

Aims: To assess frequency of elevated blood values in patients with thromboembolic event, how many of these should be investigated further regarding myeloproliferative neoplasm and if the risk of recurrent event is depending on underlying condition.

Methods: Retrospective cohort study of 3931 adult patients in the county of Norrbotten, Sweden, with thromboembolism during 2017 and 2018.

Results: Of the 3931 patients, 1195 had either elevated Hb, HCT, or platelets fulfilling the 2016 revised WHO criteria for PV and ET, and out of these 411 should be evaluated regarding underlying myeloproliferative neoplasms. Unexplained thrombocytosis and secondary erythrocytosis were associated with the highest rate of recurrent event as well as the most inferior restricted mean survival time.

Conclusion: Elevated blood values are common in patients with thromboembolic event and the high risk of recurrent event and inferior restricted mean survival time in patients with unexplained thrombocytosis and secondary erythrocytosis implicates the importance of finding and managing the underlying condition.

Place, publisher, year, edition, pages
John Wiley & Sons, 2023
Keywords
essential thrombocythemia, polycythemia, polycythemia vera, thrombocytosis, thromboembolism
National Category
Hematology
Identifiers
urn:nbn:se:umu:diva-205189 (URN)10.1111/ejh.13938 (DOI)000932888700001 ()36725666 (PubMedID)2-s2.0-85147986248 (Scopus ID)
Funder
Norrbotten County Council
Available from: 2023-02-28 Created: 2023-02-28 Last updated: 2023-07-12Bibliographically approved
Welander, F., Renlund, H., Dimény, E., Holmberg, H. & Själander, A. (2023). Warfarin treatment quality and outcomes in patients with non-valvular atrial fibrillation and CKD G3-G5D. Thrombosis Research, 229, 131-138
Open this publication in new window or tab >>Warfarin treatment quality and outcomes in patients with non-valvular atrial fibrillation and CKD G3-G5D
Show others...
2023 (English)In: Thrombosis Research, ISSN 0049-3848, E-ISSN 1879-2472, Vol. 229, p. 131-138Article in journal (Refereed) Published
Abstract [en]

Introduction: Warfarin treatment quality is calculated as time in therapeutic range (TTR). TTR ≥ 70 % is considered reducing the risk of adverse events for patients with atrial fibrillation (AF). The association of TTR and adverse events in chronic kidney disease (CKD) is however poorly investigated. The aim is to explore this further.

Materials and methods: Swedish cohort study based on national healthcare registers between 2009 and 2018, including Swedish Renal Registry, Swedish Stroke Register and AuriculA - the Swedish national quality register for AF and anticoagulation. Investigating the effect of individual TTR (iTTR) and iTTR ≥ 70 % versus <70 % on the risk of ischemic stroke, major bleeding and death for patients with CKD GFR category 3–5 (G3-G5) including patients on dialysis (G5D) and non-valvular AF (NVAF).

Results: Of 2379 included patients 21.9 % had G3, 47.5 % G4, 10.8 % G5 and 19.8 % G5D. TTR in G3 was 75.6 %, G4 72.2 %, G5 67.6 % and G5D 62.0 %. Increase by 10 percentage points iTTR conferred lower risk of major bleeding, ischemic stroke and death for all patients (hazard ratio 0.91 (95 % Confidence interval 0.87–0.94), 0.92 (0.85–0.99) and 0.88 (0.85–0.90)). iTTR≥ 70 % versus <70 % was associated with lower risk of bleeding and death in all patients (0.63 (0.51–0.77) and (0.51 (0.43–0.61)), and a non-significant tendency towards lower stroke risk (0.67 (0.43–1.06)).

Conclusions: Warfarin treatment quality worsens with decreasing GFR. Higher iTTR confers lower risk of bleeding, ischemic stroke and death in patients with NVAF and G3-G5D. iTTR ≥ 70 % was associated with better safety profile. Close monitoring of patients with CKD on warfarin is recommended.

Place, publisher, year, edition, pages
Elsevier, 2023
Keywords
Anticoagulation, Atrial fibrillation, Bleeding, Chronic kidney disease, Dialysis, Ischemic stroke, Warfarin
National Category
Cardiac and Cardiovascular Systems
Identifiers
urn:nbn:se:umu:diva-212400 (URN)10.1016/j.thromres.2023.07.003 (DOI)37453255 (PubMedID)2-s2.0-85165087883 (Scopus ID)
Funder
Swedish Heart Lung Foundation, 20200766Region Västernorrland
Available from: 2023-07-28 Created: 2023-07-28 Last updated: 2023-11-05Bibliographically approved
Jakobsson, E., Lundström, K.-J., Holmberg, H., De La Croix, H. & Nordin, P. (2022). Chronic Pain After Groin Hernia Surgery in Women: A Patient-reported Outcome Study Based on Data From the Swedish Hernia Register. Annals of Surgery, 275(2), 213-219
Open this publication in new window or tab >>Chronic Pain After Groin Hernia Surgery in Women: A Patient-reported Outcome Study Based on Data From the Swedish Hernia Register
Show others...
2022 (English)In: Annals of Surgery, ISSN 0003-4932, E-ISSN 1528-1140, Vol. 275, no 2, p. 213-219Article in journal (Refereed) Published
Abstract [en]

Objective:The aim of this study was to evaluate chronic pain 1 year after surgery, and risk factors for chronic pain after groin hernia repair in women.Background:Groin hernia surgery in women is less frequently studied than in men. Chronic pain is common after groin hernia surgery and remains an important area with room for improvement. Previous studies are small or inconclusive. Guidelines recommend timely repair of all female groin hernias.

Methods:From the Swedish Hernia Register 4021 female and 37,542 male patients operated between September 1, 2012 and August 30, 2017 responded to a patient-reported outcome questionnaire (response rate 70.0%) 1 year after primary groin hernia surgery. Multivariable analysis was performed to compare chronic postoperative pain in women with men as a control group, and to evaluate risk factors for chronic pain in women.

Results:Among women operated for groin hernia, 18% suffered chronic postoperative pain. The risk for chronic pain was significantly higher for women [odds ratio 1.3 (95% confidence interval 1.16-1.46). Three risk factors for chronic pain in women were found: High body mass index, high American Society of Anesthesiologists classification, and femoral hernia. No differences in chronic pain in women were seen when comparing surgical methods or emergency versus elective surgery.

Conclusions:Almost one-fifth of women suffered of chronic pain affecting daily activity after groin hernia repair. Chronic pain was more common for women than men. In view of the high-rate chronic postoperative pain, further research on management strategies in female groin hernia is warranted.

Place, publisher, year, edition, pages
Lippincott Williams & Wilkins, 2022
Keywords
chronic pain, femoral hernia, inguinal hernia, women
National Category
Surgery
Research subject
Surgery
Identifiers
urn:nbn:se:umu:diva-192081 (URN)10.1097/SLA.0000000000005194 (DOI)000740824400004 ()35007224 (PubMedID)2-s2.0-85123222296 (Scopus ID)
Available from: 2022-02-02 Created: 2022-02-02 Last updated: 2024-04-09Bibliographically approved
Organisations
Identifiers
ORCID iD: ORCID iD iconorcid.org/0000-0001-6206-3099

Search in DiVA

Show all publications