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Shayesteh, AlexanderORCID iD iconorcid.org/0000-0003-0700-7195
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Publications (10 of 27) Show all publications
Polesie, S., Paoli, J., Nielsen, K., Sonesson, A., Shayesteh, A., Josefson, A., . . . Hoppe, T. (2026). National learning objectives in dermatology and venereology for the new Swedish medical programme. Acta Dermato-Venereologica, 106, Article ID adv44059.
Open this publication in new window or tab >>National learning objectives in dermatology and venereology for the new Swedish medical programme
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2026 (English)In: Acta Dermato-Venereologica, ISSN 0001-5555, E-ISSN 1651-2057, Vol. 106, article id adv44059Article in journal (Refereed) Published
Abstract [en]

Effective medical education relies on clearly defined learning objectives that foster deep and meaningful learning. This article presents a consensus-driven proposal for national learning objectives in dermatology and venereology within Sweden's new medical programme qualifying for licensure. The primary aim is to harmonize educational standards across all medical faculties and to establish a common understanding of the expected level of knowledge and competence at the point of medical licensure. Using a structured approach, existing curricula were analysed and categorized according to a modified version of Bloom's taxonomy. The initial list of objectives and core conditions was then expanded through input from invited educators at all participating medical faculties as well as practising GPs. One designated assessor from each institution independently reviewed the expanded material to determine the expected knowledge level for each condition and to assess whether any items fell outside the intended scope. This process resulted in the identification of 36 learning objectives, along with a list of 124 core diagnoses and/or medications. The learning objectives encompass knowledge, practical skills, and professional attitudes in the management of dermatological and sexually transmitted diseases. The next step is to implement them with the aim of evaluating their impact on dermatology and venereology education. In this future work, student involvement should be prioritized to ensure a learner-centred approach throughout the process.

Place, publisher, year, edition, pages
MJS Publishing, 2026
Keywords
Clinical Competence, Curriculum, Dermatology/education, Education, Medical, Undergraduate, Learning, Professional Competence, Sexually Transmitted Diseases/education, Venereology/education
National Category
Dermatology and Venereal Diseases
Research subject
Dermatology and Venerology
Identifiers
urn:nbn:se:umu:diva-249074 (URN)10.2340/actadv.v106.44059 (DOI)41572869 (PubMedID)2-s2.0-105028339780 (Scopus ID)
Available from: 2026-01-26 Created: 2026-01-26 Last updated: 2026-02-09Bibliographically approved
Glas, B., Stachurska, M., Dunford, L. J. & Shayesteh, A. (2025). Food and beverage habits among individuals with primary hyperhidrosis: a case-control survey in Sweden. Clinical, Cosmetic and Investigational Dermatology, 18, 2769-2776
Open this publication in new window or tab >>Food and beverage habits among individuals with primary hyperhidrosis: a case-control survey in Sweden
2025 (English)In: Clinical, Cosmetic and Investigational Dermatology, ISSN 1178-7015, Vol. 18, p. 2769-2776Article in journal (Refereed) Published
Abstract [en]

Aim: Excessive sweat production in primary hyperhidrosis (PH) can lead to water and mineral loss, yet data on patients’ dietary habits are limited.

Purpose: To explore associations between food and beverage consumption and severe PH.

Patients and Methods: Participants with primary palmar and axillary hyperhidrosis (n=171) and without hyperhidrosis (n=165) completed a validated questionnaire on food and beverage habits at two hospitals in northern Sweden. Frequency and quantity of specific foods and beverages were compared between groups.

Results: A total of 336 individuals participated in this study (men, n=109; women, n=218; unspecified sex, n=9). Individuals with PH were younger (18–29 years, n=104 vs n=66; p<0.001) and more frequently female compared to controls (n=75 vs 58; p<0.001). Total caffeine consumption was higher in PH (median score: 186.6 vs.151.0; p<0.001), and 57% of individuals with PH consumed energy drinks weekly compared with 39.5% of controls (p<0.001). Spicy foods, fatty foods, fast foods, and sweets were reported to trigger sweating. Women with PH more often reported difficulties replenishing water loss, and increased thirst was the most reported symptom in both men and women.

Conclusion: PH was associated with higher caffeine intake, distinct beverage consumption patterns, and self-reported fluid loss symptoms. These findings indicate potential associations between diet and PH and may inform patient education and future research, although causality cannot be inferred from this study.

Place, publisher, year, edition, pages
Dove Medical Press, 2025
Keywords
beverage habits, food habits, hyperhidrosis, questionnaire survey
National Category
Dermatology and Venereal Diseases Epidemiology Public Health, Global Health and Social Medicine
Identifiers
urn:nbn:se:umu:diva-246567 (URN)10.2147/CCID.S547497 (DOI)001601377500001 ()41164747 (PubMedID)2-s2.0-105019665029 (Scopus ID)
Available from: 2025-11-20 Created: 2025-11-20 Last updated: 2025-11-20Bibliographically approved
Shayesteh, A., af Klinteberg, M., Vrang, S., Sigurdardottir, G., Sandström Falk, M. & Alsterholm, M. (2025). Health care utilization in patients with atopic dermatitis experiencing topical steroid withdrawal: observational cross-sectional social media questionnaire study. JMIR Formative Research, 9, Article ID e85183.
Open this publication in new window or tab >>Health care utilization in patients with atopic dermatitis experiencing topical steroid withdrawal: observational cross-sectional social media questionnaire study
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2025 (English)In: JMIR Formative Research, E-ISSN 2561-326X, Vol. 9, article id e85183Article in journal (Refereed) Published
Abstract [en]

Background: Topical steroid withdrawal (TSW) is a controversial skin condition among health care providers due to a lack of evidence, but it has an impactful and growing presence on social media. There are few previous reports of health care utilization for symptoms attributed to TSW.

Objective: This study aims to investigate health care utilization and requests as well as information sources for TSW among patients with atopic dermatitis (AD).

Methods: This observational cross-sectional study used a questionnaire aimed at adults with AD, experiencing symptoms they attribute to TSW. The questionnaire was posted as a link, free to share with others, in a Swedish TSW-themed Facebook group and remained accessible for 4 weeks. Descriptive statistics and topical text analysis on open-ended items were used to present and interpret the results.

Results: The participants (n=82) reported dermatologists (n=41, 50%), general practitioners (n=40, 49%), and practitioners of complementary and alternative medicine (CAM; n=32, 39%) as the most frequent health care contacts for TSW. However, among participants with ongoing symptoms attributed to TSW (n=68), ongoing health care contacts with general practitioners, dermatologists, and practitioners of CAM were reported by only 10% (n=7), 22% (n=15), and 13% (n=11), respectively. For symptoms attributed to AD, the frequencies of health care provider contacts were higher. Almost all participants had sought help from a general practitioner (n=81, 99%) or a dermatologist (n=76, 93%) at some point, and many had also consulted a practitioner of CAM (n=59, 72%). Among those with ongoing symptoms attributed to AD, 43% (n=26) had an ongoing contact with a dermatologist. Participant-requested help and support from health care providers included understanding and confirmation of TSW impairments (n=45, 56%), treatment of symptoms (n=26, 32%), and increased awareness and information about TSW from health care providers (n=21, 26%). The most common TSW information sources were Facebook (n=78, 96%), websites (n=75, 93%), and Instagram (n=45, 56%), but YouTube (n=11, 14%), podcasts (n=7, 10%), and TikTok (n=5, 6%) were also reported.

Conclusions: This study investigates health care utilization patterns related to TSW. The results indicate that the participants received insufficient support from health care providers for symptoms they attributed to TSW. The participants initiated and maintained health care provider contacts for symptoms attributed to AD to a greater extent than for TSW and sought information and support for TSW elsewhere. Targeted interventions to overcome this could be educational efforts for general practitioners and dermatologists about the current scientific knowledge of TSW as well as the TSW discourse on social media. In addition, health care providers need to engage and contribute to evidence-based content about TSW on relevant social media platforms to prevent the spread of misinformation about topical glucocorticoids.

Place, publisher, year, edition, pages
Toronto: JMIR Publications, 2025
Keywords
atopic dermatitis, red skin syndrome, topical steroid addiction, topical steroid withdrawal, topical steroid withdrawal syndrome
National Category
Dermatology and Venereal Diseases
Research subject
Dermatology and Venerology
Identifiers
urn:nbn:se:umu:diva-249073 (URN)10.2196/85183 (DOI)001659131900002 ()41474841 (PubMedID)2-s2.0-105027408004 (Scopus ID)
Available from: 2026-01-26 Created: 2026-01-26 Last updated: 2026-01-27Bibliographically approved
Dahlberg, J., Nylander, E., Persson, M. & Shayesteh, A. (2025). Struggles in accessing healthcare, the experiences made by women with lipedema in Sweden: a qualitative study. International Journal of Women's Health, Volume 17, 4949-4960
Open this publication in new window or tab >>Struggles in accessing healthcare, the experiences made by women with lipedema in Sweden: a qualitative study
2025 (English)In: International Journal of Women's Health, E-ISSN 1179-1411, Vol. Volume 17, p. 4949-4960Article in journal (Refereed) Published
Abstract [en]

Background: Lipedema is a relatively unknown condition, often leading to misdiagnosis and a lack of proper treatment.

Purpose: To explore the experiences of seeking healthcare support and treatment among women with a physician-verified diagnosis of lipedema.

Methods: Twelve women with lipedema, verified by medical examination, were interviewed using semi-structured interviews. The transcribed data was analyzed using qualitative content analysis with an inductive approach and abstracted to visualize manifest and latent meanings.

Results: The theme "Pushing the barricaded doors to treatment and care while fighting to illuminate the shadows of lipedema" describes the experiences of women being denied subsidized treatment and disregarded by healthcare professionals. The theme is based on three categories "Experiencing societal injustice and gatekeeping in healthcare services", "Combating prejudice and stigmatization with increased awareness", and "Having a solid desire for improved and affordable treatment options". Women with lipedema described feelings of being abandoned by decision-makers and healthcare. When in need of symptom relief, women with lipedema searched and attempted different therapies, and when treatment were available, the women would have to pay for it themselves.

Conclusion: Lipedema remains an unknown disease with few available treatments in subsidized healthcare. Lack of experience regarding lipedema among healthcare professionals and their failure to assess the condition risks damaging the confidence of affected women. Therefore, increased awareness and education of healthcare personnel to increase the clinical recognition of lipedema are necessary first steps to reducing misdiagnosis, improve patient satisfaction, and the availability of care among patients with lipedema.

Place, publisher, year, edition, pages
Dove Medical Press, 2025
Keywords
content analysis, women's health, treatment availability, patient experience
National Category
Nursing
Identifiers
urn:nbn:se:umu:diva-246867 (URN)10.2147/ijwh.s563416 (DOI)001628265500001 ()41333043 (PubMedID)2-s2.0-105023374849 (Scopus ID)
Funder
Region Västerbotten, RV-980786
Available from: 2025-11-27 Created: 2025-11-27 Last updated: 2025-12-11Bibliographically approved
Micu, E., Fragkou Dragka, M. & Shayesteh, A. (2025). Three-year results following microwave therapy in patients with severe primary axillary hyperhidrosis. Aesthetic Plastic Surgery
Open this publication in new window or tab >>Three-year results following microwave therapy in patients with severe primary axillary hyperhidrosis
2025 (English)In: Aesthetic Plastic Surgery, ISSN 0364-216X, E-ISSN 1432-5241Article in journal (Refereed) Epub ahead of print
Abstract [en]

Microwave therapy (Miradry®) is an approved treatment for axillary hyperhidrosis (AH). There are several studies in the literature that show favourable safety and efficacy profile, although a few follow up patients under longer period and on larger cohort patients. In the present study, we report three-year results after microwave therapy for AH. At dermatology clinic in Östergötland 103 patients with severe AH received one or two Miradry® treatments, between 2020 and 2022. Patients were examined at several intervals during study period. Between March 2024 and June 2025, 87 patients were contacted by post and asked to complete HDSS (Hyperhidrosis Disease Severity Scale) and Hyperhidrosis Quality of Life (HidroQoL©); 45 patients have responded to our survey (response rate 51.7%). Statistically significant improvement was observed in both HDSS (from medians 3 at the study inclusion to medians 2 at 3 year) and HidroQoL© (medians 26 at baseline and medians 6 at 3 year). As a conclusion, our data demonstrate that microwave therapy is a promising long-term efficient treatment for AH and significantly improves quality of life in patients suffering from severe AH.

Place, publisher, year, edition, pages
Springer, 2025
Keywords
Hyperhidrosis; Microwave; Miradry®; Quality of life.
National Category
Dermatology and Venereal Diseases
Research subject
Dermatology and Venerology; Plastic Surgery
Identifiers
urn:nbn:se:umu:diva-247128 (URN)10.1007/s00266-025-05469-5 (DOI)001628551800001 ()41326743 (PubMedID)2-s2.0-105023572345 (Scopus ID)
Funder
Medical Research Council of Southeast Sweden (FORSS), FORSS-932159Medical Research Council of Southeast Sweden (FORSS), FORSS-969108Linköpings universitet
Available from: 2025-12-02 Created: 2025-12-02 Last updated: 2025-12-12
Alsterholm, M., af Klinteberg, M., Vrang, S., Sigurdardottir, G., Sandström Falk, M. & Shayesteh, A. (2025). Topical steroid withdrawal in atopic dermatitis: patient-reported characterization from a Swedish social media questionnaire. Acta Dermato-Venereologica, 105, Article ID adv40187.
Open this publication in new window or tab >>Topical steroid withdrawal in atopic dermatitis: patient-reported characterization from a Swedish social media questionnaire
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2025 (English)In: Acta Dermato-Venereologica, ISSN 0001-5555, E-ISSN 1651-2057, Vol. 105, article id adv40187Article in journal (Refereed) Published
Abstract [en]

Topical steroid withdrawal (TSW) is described as an adverse reaction to topical glucocorticoids (TGCs). A pathophysiological mechanism has not been identified. There are no diagnostic criteria. The aim was to describe patient-reported characteristics of TSW in atopic dermatitis (AD). An observational cross-sectional study was performed by posting a questionnaire for participants, aged ≥18 years, reporting both AD and TSW, in a Swedish TSW-themed Facebook group during 4 weeks in 2023. The questionnaire was accessed by 98 participants, with 82 completing it. Most were female (95%), 18-39 years old (74%), self-diagnosed with TSW (84%), and reported current symptoms of AD and TSW. They defined TSW as dependency on TGCs and adverse reactions to their use. Erythema, desquamation, dryness, and oozing affecting the face, neck, and upper extremities were the most reported signs. Pruritus, sleep disturbance, and signs of anxiety and depression were the most reported symptoms. Recurring episodes of manifestations attributed to TSW were reported by 60%. The personal trigger factor was believed to be TGCs by 93%, and 33% also identified oral glucocorticoids. TGCs were currently used by 21%. Self-reported manifestations of TSW are similar to those of AD but appeared to be distinguishable for the participants and caused considerable morbidity.

Place, publisher, year, edition, pages
Medical Journals Sweden, 2025
Keywords
atopic dermatitis, red skin syndrome, topical steroid addiction, topical steroid withdrawal, topical steroid withdrawal syndrome
National Category
Dermatology and Venereal Diseases
Identifiers
urn:nbn:se:umu:diva-234320 (URN)10.2340/actadv.v105.40187 (DOI)39749386 (PubMedID)2-s2.0-85214590123 (Scopus ID)
Available from: 2025-01-22 Created: 2025-01-22 Last updated: 2025-01-22Bibliographically approved
Stjernbrandt, A.-L., Burstedt, M., Holmbom, E. & Shayesteh, A. (2024). Acral peeling skin syndrome: two unusual cases and the therapeutic potential of botulinum toxin. Acta Dermato-Venereologica, 104, Article ID adv24305.
Open this publication in new window or tab >>Acral peeling skin syndrome: two unusual cases and the therapeutic potential of botulinum toxin
2024 (English)In: Acta Dermato-Venereologica, ISSN 0001-5555, E-ISSN 1651-2057, Vol. 104, article id adv24305Article in journal (Refereed) Published
Abstract [en]

No abstract available

Place, publisher, year, edition, pages
Uppsala: Medical Journals Sweden, 2024
Keywords
Acral Peeling Skin Syndrome, genetic counseling, botulinumtoxin, case-reports
National Category
Dermatology and Venereal Diseases
Research subject
Dermatology and Venerology; Clinical Genetics
Identifiers
urn:nbn:se:umu:diva-223205 (URN)10.2340/actadv.v104.24305 (DOI)2-s2.0-85190342839 (Scopus ID)
Available from: 2024-04-11 Created: 2024-04-11 Last updated: 2024-04-24Bibliographically approved
Dahlberg, J., Nylander, E., Persson, M. & Shayesteh, A. (2024). An uncertain uphill battle: experiences and consequences of living with lipedema. International Journal of Qualitative Studies on Health and Well-being, 19(1), Article ID 2300152.
Open this publication in new window or tab >>An uncertain uphill battle: experiences and consequences of living with lipedema
2024 (English)In: International Journal of Qualitative Studies on Health and Well-being, ISSN 1748-2623, E-ISSN 1748-2631, Vol. 19, no 1, article id 2300152Article in journal (Refereed) Published
Abstract [en]

Purpose: To describe and analyse experiences of living with lipedema. Methods: Individual, semi-structured interviews with a purposive sample of 12 women diagnosed with lipedema and analysed by qualitative content analysis utilizing an inductive approach.

Results: The overarching theme, “An uncertain uphill battle against a divergent body and societal ignorance”, covers the experiences of living with lipedema and is based on five categories; “Captivated by a disintegrating body”, “Face the impairments of a chronic condi-tion”, “Experience social exclusion”, “Need emotional support to go on” and “Mull over an insecure future”. The women felt entrapped within their bodies and experienced social exclusion due to the chronic symptoms and the progressive body shape alteration caused by their illness. Having experienced deficient information on the illness, varying support from other people, and a deteriorating economic situation, the women face an uncertain future.

Conclusions: Symptoms and restrictions caused by lipedema affect women’s livelihood and future, as there are no indications for disease improvement. Preventive work aimed at reducing health deterioration should be a priority. More research is needed to raise health-care awareness regarding difficulties experienced by patients with lipedema.

Place, publisher, year, edition, pages
Taylor & Francis, 2024
Keywords
Lipedema, Women, Qualitative research, Content analysis, Body Image
National Category
Dermatology and Venereal Diseases
Research subject
Dermatology and Venerology
Identifiers
urn:nbn:se:umu:diva-218759 (URN)10.1080/17482631.2023.2300152 (DOI)001133286800001 ()38159285 (PubMedID)2-s2.0-85181414770 (Scopus ID)
Funder
Region Västerbotten
Available from: 2023-12-31 Created: 2023-12-31 Last updated: 2024-08-14Bibliographically approved
Pissa, M., Hashem, R., Shayesteh, A., Wrisley, S. & Micu, E. (2024). Evaluation of quality of life, anxiety, and depression in patients with primary axillary hyperhidrosis undergoing treatment with a microwave device: one-year follow-up. Acta Dermato-Venereologica, 104
Open this publication in new window or tab >>Evaluation of quality of life, anxiety, and depression in patients with primary axillary hyperhidrosis undergoing treatment with a microwave device: one-year follow-up
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2024 (English)In: Acta Dermato-Venereologica, ISSN 0001-5555, E-ISSN 1651-2057, Vol. 104Article in journal (Refereed) Published
Abstract [en]

Hyperhidrosis is associated with social and emotional stress, affecting quality of life. Microwave energy technology treats primary axillary hyperhidrosis by thermolysis of sweat glands. The successful reduction of sweating in patients with primary axillary hyperhidrosis after microwave treatment has been studied, but there is limited evidence on the psychological and long-term effects. This study examined patient- reported outcome measures including depression and anxiety in patients with primary axillary hyperhidrosis and the effect of microwave therapy on these parameters. Patients received 1 or 2 microwave-based treatments, within 3-month intervals. All patients were finally examined at approximately 1 year after the first treatment using the Hyperhidrosis Disease Severity Scale, Hyperhidrosis Quality of Life©, Dermatology Life Quality Index, and Hospital Anxiety and Depression Scale©. A total of 103 individuals with primary axillary hyperhidrosis were included in the study, with a Hyperhidrosis Disease Severity Scale score of 3 or 4. Statistically significant improvement in quality of life, anxiety, and depression scores were observed at 1-year follow-up. The primary endpoint, Hyperhidrosis Disease Severity Scale of 2 or less 1 year after the first treatment, was achieved by 88.2% of patients. No serious adverse side effects were observed.

Place, publisher, year, edition, pages
Uppsala: Medical Journals Sweden, 2024
Keywords
axillary, hyperhidrosis, microwave, quality of life, anxiety
National Category
Dermatology and Venereal Diseases
Research subject
Dermatology and Venerology
Identifiers
urn:nbn:se:umu:diva-229239 (URN)10.2340/actadv.v104.40543 (DOI)001314683800005 ()39235052 (PubMedID)2-s2.0-85203322221 (Scopus ID)
Funder
Medical Research Council of Southeast Sweden (FORSS), FORSS-932159, FORSS-969108
Available from: 2024-09-05 Created: 2024-09-05 Last updated: 2025-04-24Bibliographically approved
Shayesteh, A., Boman, J. & Nylander, E. (2024). Impostor phenomenon is a common feature among individuals with primary hyperhidrosis. SAGE Open Medicine, 12, Article ID 20503121231220828.
Open this publication in new window or tab >>Impostor phenomenon is a common feature among individuals with primary hyperhidrosis
2024 (English)In: SAGE Open Medicine, E-ISSN 2050-3121, Vol. 12, article id 20503121231220828Article in journal (Refereed) Published
Abstract [en]

Background: Primary hyperhidrosis consists of excessive focal sweating. Affected individuals camouflage the sweating on their body, avoiding stigmatisation. Hence, misrepresentation in social interactions is a common feature in patients with hyperhidrosis. The aim of this study was to investigate impostor phenomenon, perfectionism, self-compassion, stress and anxiety among individuals with primary hyperhidrosis.

Methods: A cross-sectional study was conducted at our clinic among 100 participants with axillary and palmar primary hyperhidrosis. The questionnaire contained a hyperhidrosis part and Perceived Stress Scale-4, Generalised Anxiety Disorder Scale-2, Clinical Perfectionism Questionnaire-6, Self-Compassion Scale Short form and Clance Impostor Phenomenon Scale. Descriptive statistics was used for analyses of categorical variables. As data were normally distributed independent t-test and one-way analysis of variance with post hoc Tukey test were used to compare the mean values for the questionnaires with other variables. Pearson's correlation was used, and a forward multiple linear regression model was performed to predict presence of impostor phenomenon with gender, age and other scales in this study.

Results: Impostor phenomenon occurred in almost half of our patients (48%) with hyperhidrosis. While feelings of impostor phenomenon were more common in women, there was no difference between gender regarding its intensity levels (p = 0.07). In addition, we found a significant (p < 0.001) negative correlation between impostor phenomenon and self-compassion, while feelings of impostor phenomenon increased with stress, anxiety and perfectionism (p < 0.001).

Conclusions: Feelings of impostor phenomenon was found in 48% of individuals with hyperhidrosis which indicates that it is a common feature in this patient group. Future research is warranted regarding the prevalence of impostor phenomenon in hyperhidrosis and other medical conditions, among men and women, seeking medical healthcare. Psychological interventions in hyperhidrosis may be beneficial both for the individual and in public health, by facilitating management of patients' daily lives and saving considerable resources in healthcare regarding pharmacological interventions and medical consultations.

Place, publisher, year, edition, pages
Sage Publications, 2024
Keywords
Primary hyperhidrosis, impostor phenomenon, perfectionism, self-compassion, questionnaires, Hyperhidros, Impostor fenomen, Stress, Perfektionism, Ångest
National Category
Dermatology and Venereal Diseases
Research subject
Psychology; Dermatology and Venerology
Identifiers
urn:nbn:se:umu:diva-220178 (URN)10.1177/20503121231220828 (DOI)001152422600001 ()38283646 (PubMedID)2-s2.0-85183639679 (Scopus ID)
Available from: 2024-01-29 Created: 2024-01-29 Last updated: 2024-06-25Bibliographically approved
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ORCID iD: ORCID iD iconorcid.org/0000-0003-0700-7195

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