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Karlsson, S., Björklund, I., Burman, A., Israelsson, L. & Cengiz, Y. (2024). Long-term follow-up after incisional hernia repair: dynamics of recurrence and patient-reported outcome. World Journal of Surgery, 48, 2109-2119
Open this publication in new window or tab >>Long-term follow-up after incisional hernia repair: dynamics of recurrence and patient-reported outcome
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2024 (English)In: World Journal of Surgery, ISSN 0364-2313, E-ISSN 1432-2323, Vol. 48, p. 2109-2119Article in journal (Refereed) Published
Abstract [en]

Background: Incisional hernia (IH) is common and recurrence rates remain high. Although the goal of treatment should be to improve quality of life, studies addressing this aspect are notably absent. We aimed to evaluate the long-term recurrence rate of open mesh repair of IH, investigate the burden of persisting discomfort, explore patient satisfaction, and identify risk factors for negative outcomes.

Methods: A single-center, retrospective study was conducted on all open mesh repairs of IH performed between January 2002 and October 2013. Clinical data were gathered from medical records and operative reports, while patient-reported outcome measures (PROMs) were obtained through telephone interviews. Risk factors for recurrence were assessed by survival analysis. PROMs were analyzed across patient subgroups by clinical and demographic variables.

Results: This study included 271 patients undergoing medical record review, with 136 patients completing the telephone interview. Recurrence rates at 2, 5, 10, and 15 years were 6%, 8%, 11%, and 12%, respectively. Risk factors for recurrence were obesity and an estimated mesh-defect overlap <7 cm. Bridged repair posed no increased risk. For PROMs, the median follow-up time was 13.6 years after which 78.7% of the patients reported no discomfort, and 89.0% were satisfied with their surgery. Patients <65 years and females experienced more long-term discomfort.

Conclusions: Recurrence rates were higher in obese patients and when the estimated mesh-defect overlap was <7 cm, but not in bridged repairs. Young patients and females are at increased risk for long-term discomfort. High satisfaction levels were reported.

Place, publisher, year, edition, pages
John Wiley & Sons, 2024
Keywords
follow-up, hernia recurrence, hernia repair, incisional hernia, patient-reported outcome, risk factor
National Category
Surgery
Identifiers
urn:nbn:se:umu:diva-228042 (URN)10.1002/wjs.12294 (DOI)001272881800001 ()39031947 (PubMedID)2-s2.0-85198959147 (Scopus ID)
Available from: 2024-07-25 Created: 2024-07-25 Last updated: 2025-04-24Bibliographically approved
Cengiz, Y., Lund, M., Jänes, A., Lundell, L., Sandblom, G. & Israelsson, L. (2019). Fundus first as the standard technique for laparoscopic cholecystectomy. Scientific Reports, 9, Article ID 18736.
Open this publication in new window or tab >>Fundus first as the standard technique for laparoscopic cholecystectomy
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2019 (English)In: Scientific Reports, E-ISSN 2045-2322, Vol. 9, article id 18736Article in journal (Refereed) Published
Abstract [en]

In previous studies the fundus first technique (FF) has been a cost-effective way to simplify the laparoscopic cholecystectomy (LC) and facilitate patient rehabilitation. The feasibility and safety profile when introducing FF as the standard technique were aimed in this study. Between 2004-2014, 29 surgeons performed 1425 LC with FF and 320 with a conventional technique. During the first year 56% were with FF and 98% during the last four years. More females, ultrasonic shears, urgent operations, daycare operations and a shorter operation time were found with FF. 63 (3.6%) complications occurred: 10 (0.6%) bleedings, 33 (1.9%) infections and 12 (0.7%) bile leakages. Leakage from cystic duct occurred in 4/112 (3.6%) when closed with ultrasonic shears and in 4/1633 (0.2%) with clips (p 0.008). A common bile duct lesion occurred in 1/1425 (0.07%) with FF and in 3/320 (0.9%) with the conventional approach (p 0.003). In a multivariate regression model, the conventional technique was a risk factor for bile duct injury with an odds ratio of 20.8 (95%CI 1.6-259.2). In conclusion FF was effectively established as the standard procedure and associated with lower rates of bile duct injuries. Clipless closure of the cystic duct increased the rate of leakage.

Place, publisher, year, edition, pages
Nature Publishing Group, 2019
National Category
Surgery
Identifiers
urn:nbn:se:umu:diva-167056 (URN)10.1038/s41598-019-55401-6 (DOI)000502008800001 ()31822771 (PubMedID)2-s2.0-85076381716 (Scopus ID)
Available from: 2020-01-09 Created: 2020-01-09 Last updated: 2023-03-23Bibliographically approved
Israelsson, L. & Janson, A. (2018). Parastomal hernia (5ed.). In: Karl A. Leblanc; Andrew Kingsnorth; David L. Sanders (Ed.), Management of abdominal hernias: (pp. 449-460). Springer
Open this publication in new window or tab >>Parastomal hernia
2018 (English)In: Management of abdominal hernias / [ed] Karl A. Leblanc; Andrew Kingsnorth; David L. Sanders, Springer, 2018, 5, p. 449-460Chapter in book (Refereed)
Place, publisher, year, edition, pages
Springer, 2018 Edition: 5
National Category
Surgery
Identifiers
urn:nbn:se:umu:diva-203511 (URN)10.1007/978-3-319-63251-3_34 (DOI)2-s2.0-85060438072 (Scopus ID)9783319632513 (ISBN)9783319632506 (ISBN)
Available from: 2023-01-18 Created: 2023-01-18 Last updated: 2023-01-19Bibliographically approved
Ahlqvist, S., Björk, D., Weisby, L., Israelsson, L. & Cengiz, Y. (2017). Trocar Site Hernia After Gastric Bypass. Surgical technology international, 30, 170-174
Open this publication in new window or tab >>Trocar Site Hernia After Gastric Bypass
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2017 (English)In: Surgical technology international, ISSN 1090-3941, Vol. 30, p. 170-174Article in journal (Refereed) Published
Abstract [en]

BACKGROUND: The 5.2% rate of trocar site incisional hernia (TSIH) reported appears low in view of the proportion of TSIH repairs being performed. Detecting TSIH by clinical examination may be difficult in the obese. The correlation between clinical examination and a novel radiological examination for the detection of TSIH in obese patients was studied.

MATERIALS AND METHODS: Twenty-six patients subjected to laparoscopic gastric bypass in 2010 underwent clinical and radiological examination by three independent assessors for each method, after a mean follow-up time of 33 months. The computed tomography was in the prone position upon a ring.

RESULTS: At clinical examination, a TSIH was regarded to be present in six out of 26 patients and at CT scan in four. The Fleiss' Kappa for multiple raters was 0.40 (p = 0.184) with clinical examination and 1 (p <0.05) with CT scan. With CT scan, herniation was diagnosed in three of 26 umbilical trocar sites that had been closed at the index operation, and in one of the 130 other trocar sites that had not been closed.

CONCLUSIONS: Clinical examination is not reliable when detecting TSIH in the obese. A CT scan in the prone position was extremely reliable and seems to have the potential of becoming the standard method for detecting TSIH in obese patients.

National Category
Surgery
Identifiers
urn:nbn:se:umu:diva-200193 (URN)28696492 (PubMedID)2-s2.0-85056973180 (Scopus ID)
Available from: 2022-10-13 Created: 2022-10-13 Last updated: 2022-10-13Bibliographically approved
Israelsson, L. A. (2015). Abdominal incision closure: small but important bites. The Lancet, 386(10000), 1216-1218
Open this publication in new window or tab >>Abdominal incision closure: small but important bites
2015 (English)In: The Lancet, ISSN 0140-6736, E-ISSN 1474-547X, Vol. 386, no 10000, p. 1216-1218Article in journal, Editorial material (Other academic) Published
Place, publisher, year, edition, pages
Elsevier, 2015
National Category
Surgery
Identifiers
urn:nbn:se:umu:diva-109907 (URN)10.1016/S0140-6736(15)60687-0 (DOI)000361700100006 ()2-s2.0-84943454211 (Scopus ID)
Available from: 2015-10-15 Created: 2015-10-09 Last updated: 2023-03-24Bibliographically approved
Björk, D., Cengiz, Y., Weisby, L. & Israelsson, L. (2015). Detecting incisional hernia at clinical and radiological examination. Surgical technology international, 26, 128-131
Open this publication in new window or tab >>Detecting incisional hernia at clinical and radiological examination
2015 (English)In: Surgical technology international, ISSN 1090-3941, Vol. 26, p. 128-131Article in journal (Refereed) Published
Abstract [en]

PURPOSE: In clinical studies, incisional hernia is usually diagnosed by clinical examination. No other modality has been proven an aid in the diagnosis. The aim was to investigate the correlation between findings at clinical examination and at computed tomography when detecting incisional hernia after midline incisions.

METHODS: Patients underwent clinical examination by three surgeons. Computed tomography was performed in both the supine position and in the prone position and was examined by three radiologists. The correlation between investigators and methods were estimated by calculating the Fleiss Kappa values.

RESULTS: Twenty-four patients were assessed. For the clinical examination, the Kappa was 0.81. For computed tomography with the patient in the supine position, the Kappa was 0.94 and in the prone position it was 0.89. The Kappa for clinical examination and computed tomography combined was 0.80.

CONCLUSIONS: At clinical examination, incisional hernia can be defined as any detectable defect in the abdominal wall with intra-abdominal contents protruding beyond the aponeurosis. The same definition can be used at computed tomography with the addition that any visible hernia sac is also regarded an incisional hernia. With this definition, there is very good agreement between investigators at clinical investigation and at computed tomography in the prone or in the supine position. The highest agreement among investigators is achieved with computed tomography in the supine position. In clinical studies, clinical examination seems adequate for diagnosing herniation but in overweight patients a CT-scan may be a further aid.

Place, publisher, year, edition, pages
Surgical Technology Online, 2015
National Category
Surgery
Identifiers
urn:nbn:se:umu:diva-199959 (URN)26055000 (PubMedID)2-s2.0-84952769379 (Scopus ID)
Available from: 2022-10-14 Created: 2022-10-14 Last updated: 2024-08-23Bibliographically approved
Muysoms, F. E., Antoniou, S. A., Bury, K., Campanelli, G., Conze, J., Cuccurullo, D., . . . Berrevoet, F. (2015). European Hernia Society guidelines on the closure of abdominal wall incisions. Hernia, 19(1), 1-24
Open this publication in new window or tab >>European Hernia Society guidelines on the closure of abdominal wall incisions
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2015 (English)In: Hernia, ISSN 1265-4906, E-ISSN 1248-9204, Vol. 19, no 1, p. 1-24Article, review/survey (Refereed) Published
Abstract [en]

Background The material and the surgical technique used to close an abdominal wall incision are important determinants of the risk of developing an incisional hernia. Optimising closure of abdominal wall incisions holds a potential to prevent patients suffering from incisional hernias and for important costs savings in health care. Methods The European Hernia Society formed a Guidelines Development Group to provide guidelines for all surgical specialists who perform abdominal incisions in adult patients on the materials and methods used to close the abdominal wall. The guidelines were developed using the Grading of Recommendations Assessment, Development and Evaluation (GRADE) approach and methodological guidance was taken from Scottish Intercollegiate Guidelines Network (SIGN). The literature search included publications up to April 2014. The guidelines were written using the AGREE II instrument. An update of these guidelines is planned for 2017. Results For many of the Key Questions that were studied no high quality data was detected. Therefore, some strong recommendations could be made but, for many Key Questions only weak recommendations or no recommendation could be made due to lack of sufficient evidence. Recommendations To decrease the incidence of incisional hernias it is strongly recommended to utilise a non-midline approach to a laparotomy whenever possible. For elective midline incisions, it is strongly recommended to perform a continuous suturing technique and to avoid the use of rapidly absorbable sutures. It is suggested using a slowly absorbable monofilament suture in a single layer aponeurotic closure technique without separate closure of the peritoneum. A small bites technique with a suture to wound length (SL/WL) ratio at least 4/1 is the current recommended method of fascial closure. Currently, no recommendations can be given on the optimal technique to close emergency laparotomy incisions. Prophylactic mesh augmentation appears effective and safe and can be suggested in high-risk patients, like aortic aneurysm surgery and obese patients. For laparoscopic surgery, it is suggested using the smallest trocar size adequate for the procedure and closure of the fascial defect if trocars larger or equal to 10 mm are used. For single incision laparoscopic surgery, we suggest meticulous closure of the fascial incision to avoid an increased risk of incisional hernias.

Keywords
Guidelines, Abdominal wall closure, Laparotomy, Laparoscopy, Prophylactic mesh, Prevention, cisional hernia
National Category
Surgery
Identifiers
urn:nbn:se:umu:diva-102384 (URN)10.1007/s10029-014-1342-5 (DOI)000351701000001 ()25618025 (PubMedID)2-s2.0-84991389289 (Scopus ID)
Available from: 2015-05-22 Created: 2015-04-23 Last updated: 2023-03-24Bibliographically approved
Styrke, J., Johansson, M., Granåsen, G. & Israelsson, L. (2015). Parastomal hernia after Heal conduit with a prophylactic mesh: a 10 year consecutive case series. Scandinavian journal of urology, 49(4), 308-312
Open this publication in new window or tab >>Parastomal hernia after Heal conduit with a prophylactic mesh: a 10 year consecutive case series
2015 (English)In: Scandinavian journal of urology, ISSN 2168-1805, E-ISSN 2168-1813, Vol. 49, no 4, p. 308-312Article in journal (Refereed) Published
Abstract [en]

Objective. There are no data on the frequency of parastomal hernia (PSH) after heal conduit with a prophylactic mesh. The primary objective of this study was to determine the prevalence of PSH. Secondary objectives were to elaborate whether age, gender, body mass index (BMI), previous laparotomy or diabetes influenced the outcome; and to find any mesh-related complications. Materials and methods. In a single centre during 2003-2012, a large-pore, lightweight mesh was placed in a sublay position in 114 consecutive patients with ileal conduits. Preoperative and postoperative patient data were retrospectively collected and cross-sectional follow-up was conducted. During the predefined clinical examination a PSH was defined as any protrusion in the vicinity of the ostomy with the patient straining in both an erect and a supine position. Results. Fifty-eight patients (24 women and 34 men, mean age 69 years) had follow-up examinations after a mean of 35 months (median 32 months). Bladder cancer was the most common cause for surgery. Eight patients (14%) had a PSH. Age, gender, BMI, previous laparotomy and diabetes did not affect the outcome. No mesh-related complications occurred among the 114 patients with a prophylactic mesh. Conclusions. The prevalence of PSH after ileal conduit with a prophylactic mesh corresponded to that of colostomies with a prophylactic mesh. A prophylactic mesh did not seem to be associated with complications. The degree to which a prophylactic mesh may reduce the rate of PSH after an ileal conduit should be established in randomized trials.

Keywords
bladder cancer, ostomy, parastomal hernia, surgical mesh, urinary diversion
National Category
Clinical Medicine
Identifiers
urn:nbn:se:umu:diva-107861 (URN)10.3109/21681805.2015.1005664 (DOI)000359170200007 ()25656978 (PubMedID)2-s2.0-84937554618 (Scopus ID)
Available from: 2015-09-16 Created: 2015-08-28 Last updated: 2025-02-18Bibliographically approved
Millbourn, D., Wimo, A. & Israelsson, L. A. (2014). Cost analysis of the use of small stitches when closing midline abdominal incisions. Hernia, 18(6), 775-780
Open this publication in new window or tab >>Cost analysis of the use of small stitches when closing midline abdominal incisions
2014 (English)In: Hernia, ISSN 1265-4906, E-ISSN 1248-9204, Vol. 18, no 6, p. 775-780Article in journal (Refereed) Published
Keywords
Cost analysis, Costs, Hernia, Postoperative complications, Surgical wound infection, Wound closure techniques
National Category
Surgery
Identifiers
urn:nbn:se:umu:diva-55174 (URN)10.1007/s10029-013-1135-2 (DOI)000345702100001 ()2-s2.0-84879755197 (Scopus ID)
Note

Originally included in thesis in manuscript form.

Available from: 2012-05-10 Created: 2012-05-10 Last updated: 2023-03-24Bibliographically approved
van Ramshorst, G. H., Klop, B., Hop, W. C., Israelsson, L. A. & Lange, J. F. (2013). Closure of midline laparotomies by means of small stitches: practical aspects of a new technique. Surgical technology international, 23(1), 34-38
Open this publication in new window or tab >>Closure of midline laparotomies by means of small stitches: practical aspects of a new technique
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2013 (English)In: Surgical technology international, ISSN 1090-3941, Vol. 23, no 1, p. 34-38Article in journal (Refereed) Published
Abstract [en]

Randomized studies support the closure of midline incisions with a suture length to wound length ratio (SL:WL) of more than 4, accomplished with small tissue bites and short stitch intervals to decrease the risk of incisional hernia and wound infection. We investigated practical aspects of this technique possibly hampering the introduction of this technique. Patient data, operative variables and SL:WL ratio were collected at two hospitals: Sundsvall Hospital (SH) and Erasmus University Medical Center (EMC). A structured implementation of the technique had been performed at SH but not at EMC. Personnel were interviewed by questionnaire. At each hospital, 18 closures were analyzed. Closure time was significantly longer (p = 0.023) at SH (median 18 minutes, range: 9-59) than at EMC (median 13 minutes, range: 5-23). An SL:WL ratio of more than 4 was achieved in 8 of 18 cases at EMC and in all 18 cases at SH. We conclude that calculation of an SL:WL ratio is easily performed. Suturing with the small bite-short stitch interval technique of SH required 5 minutes extra, outweighing the morbidity of incisional hernia. Without a structured implementation to suture with an SL:WL ratio of more than 4, a lower ratio is often achieved.

Place, publisher, year, edition, pages
Universal Medical Press, Incorporated, 2013
National Category
Surgery
Identifiers
urn:nbn:se:umu:diva-88085 (URN)24081841 (PubMedID)2-s2.0-84897574211 (Scopus ID)
Available from: 2014-04-23 Created: 2014-04-23 Last updated: 2023-03-23Bibliographically approved
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ORCID iD: ORCID iD iconorcid.org/0000-0003-0656-2779

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