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Publications (10 of 37) Show all publications
Carlsen, H. K., Haga, S. L., Olsson, D., Behndig, A. F., Modig, L., Meister, K., . . . Olin, A.-C. (2022). Birch pollen, air pollution and their interactive effects on airway symptoms and peak expiratory flow in allergic asthma during pollen season: a panel study in Northern and Southern Sweden. Environmental Health, 21(1), Article ID 63.
Open this publication in new window or tab >>Birch pollen, air pollution and their interactive effects on airway symptoms and peak expiratory flow in allergic asthma during pollen season: a panel study in Northern and Southern Sweden
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2022 (English)In: Environmental Health, E-ISSN 1476-069X, Vol. 21, no 1, article id 63Article in journal (Refereed) Published
Abstract [en]

Background: Evidence of the role of interactions between air pollution and pollen exposure in subjects with allergic asthma is limited and need further exploration to promote adequate preventive measures. The objective of this study was to assess effects of exposure to ambient air pollution and birch pollen on exacerbation of respiratory symptoms in subjects with asthma and allergy to birch.

Methods: Thirty-seven subjects from two Swedish cities (Gothenburg and Umeå) with large variation in exposure to both birch-pollen and air pollutants, participated in the study. All subjects had confirmed allergy to birch and self-reported physician-diagnosed asthma. The subjects recorded respiratory symptoms such as rhinitis or eye irritation, dry cough, dyspnoea, the use of any asthma or allergy medication and peak respiratory flow (PEF), daily for five consecutive weeks during two separate pollen seasons and a control season without pollen. Nitrogen oxides (NOx), ozone (O3), particulate matter (PM2.5), birch pollen counts, and meteorological data were obtained from an urban background monitoring stations in the study city centres. The data were analysed using linear mixed effects models.

Results: During pollen seasons all symptoms and medication use were higher, and PEF was reduced in the subjects. In regression analysis, exposure to pollen at lags 0 to 2 days, and lags 0 to 6 days was associated with increased ORs of symptoms and decreased RRs for PEF. Pollen and air pollution interacted in some cases; during low pollen exposure, there were no associations between air pollution and symptoms, but during high pollen exposure, O3 concentrations were associated with increased OR of rhinitis or eye irritation, and PM2.5 concentrations were associated with increased ORs of rhinitis or eye irritation, dyspnea and increased use of allergy medication. Conclusions: Pollen and air pollutants interacted to increase the effect of air pollution on respiratory symptoms in allergic asthma. Implementing the results from this study, advisories for individuals with allergic asthma could be improved, minimizing the morbidities associated with the condition.

Place, publisher, year, edition, pages
BioMed Central (BMC), 2022
Keywords
Allergic asthma, Betula, Birch, O3, Panel study, PM2.5, Pollen season
National Category
Occupational Health and Environmental Health Respiratory Medicine and Allergy
Identifiers
urn:nbn:se:umu:diva-198028 (URN)10.1186/s12940-022-00871-x (DOI)000821602700002 ()2-s2.0-85133417417 (Scopus ID)
Funder
Swedish Research Council FormasSwedish Heart Lung Foundation, 2013 − 0279Swedish Heart Lung Foundation, 2016 − 0250Swedish Research Council, 210-2013-805Swedish Asthma and Allergy Association
Available from: 2022-07-15 Created: 2022-07-15 Last updated: 2023-09-05Bibliographically approved
Wahlström, V., Nygren, M., Olsson, D., Bergman, F. & Lewis, C. A. (2022). Validity of Three Survey Questions for Self-Assessed Sedentary Time. International Journal of Environmental Research and Public Health, 19(7), Article ID 4269.
Open this publication in new window or tab >>Validity of Three Survey Questions for Self-Assessed Sedentary Time
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2022 (English)In: International Journal of Environmental Research and Public Health, ISSN 1661-7827, E-ISSN 1660-4601, Vol. 19, no 7, article id 4269Article in journal (Refereed) Published
Abstract [en]

Time spent in sedentary behavior (SB) has increased during the last decades. Accurate assessments are of importance when studying health consequences of SB. This study aimed to assess concurrent validity between three different questions for self-reported sitting and thigh worn accelerometer data. In total, 86 participants wore the ActivPAL accelerometer during three separate weeks, assessing sitting time with different questions each week. The questions used were Katzmarzyk, GIH stationary single-item question (SED-GIH), and a modified version of the singleitem from IPAQ short form. In total 64, 57, and 55 participants provided valid accelerometer and questionnaire data at each time-point, respectively, and were included for analysis. Spearman and Pearson correlation was used to assess the validity. The three questions, Katzmarzyk, SED-GIH, and a modified question from IPAQ all showed a weak non-significant correlation to ActivPAL with r-values of 0.26, 0.25, and 0.19 respectively. For Katzmarzyk and SED-GIH, 50% and 37% reported correctly, respectively. For the modified IPAQ, 53% over-reported and 47% under-reported their sitting time. In line with previous research, our study shows poor validity for self-reported sitting-time. For future research, the use of sensor-based data on SB are of high importance.

Place, publisher, year, edition, pages
MDPI, 2022
Keywords
questionnaire, sedentary behavior, self-reported, sensor-based measurements, sitting
National Category
Public Health, Global Health, Social Medicine and Epidemiology
Identifiers
urn:nbn:se:umu:diva-193800 (URN)10.3390/ijerph19074269 (DOI)000781088000001 ()35409948 (PubMedID)2-s2.0-85127438486 (Scopus ID)
Funder
AFA Insurance, 140308Region Västerbotten
Available from: 2022-05-06 Created: 2022-05-06 Last updated: 2023-05-26Bibliographically approved
Olsson, D., Forsberg, B., Bråbäck, L., Geels, C., Brandt, J., Christensen, J. H., . . . Oudin, A. (2021). Early childhood exposure to ambient air pollution is associated with increased risk of paediatric asthma: An administrative cohort study from Stockholm, Sweden. Environment International, 155, Article ID 106667.
Open this publication in new window or tab >>Early childhood exposure to ambient air pollution is associated with increased risk of paediatric asthma: An administrative cohort study from Stockholm, Sweden
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2021 (English)In: Environment International, ISSN 0160-4120, E-ISSN 1873-6750, Vol. 155, article id 106667Article in journal (Refereed) Published
Abstract [en]

Introduction: Asthma is a complex, heterogeneous disease and one of the most common chronic diseases among children. Exposure to ambient air pollution in early life and childhood may influence asthma aetiology, but it is uncertain which specific components of air pollution and exposure windows are of importance. The role of socioeconomic status (SES) is also unclear. The aims of the present study are, therefore, to investigate how various exposure windows of different pollutants affect risk-induced asthma in early life and to explore the possible effect SES has on that relationship.

Methods: The study population was constructed using register data on all singleton births in the greater Stockholm area between 2006 and 2013. Exposure to ambient black carbon (BC), fine particulate matter (PM2.5), primary organic carbon (pOC) secondary organic aerosols (SOA), secondary inorganic aerosols, and oxidative potential at the residential address was modelled as mean values for the entire pregnancy period, the first year of life and the first three years of life. Swedish national registers were used to define the outcome: asthma diagnosis assessed at hospital during the first six years of life. Hazard ratios (HRs) and their 95% confidence intervals (CIs) were modelled with Cox proportional hazards model with age as the underlying time-scale, adjusting for relevant potential confounding variables.

Results: An increased risk for developing childhood asthma was observed in association with exposure to PM2.5, pOC and SOA during the first three years of life. With an interquartile range increase in exposure, the HRs were 1.06 (95% CI: 1.01-1.10), 1.05 (95% CI: 1.02-1.09) and 1.02 (95% CI: 1.00-1.04), for PM2.5, pOC and SOA, respectively, in the fully adjusted models. Exposure during foetal life or the first year of life was not associated with asthma risk, and the other pollutants were not statistically significantly associated with increased risk. Furthermore, the increase in risk associated with PM2.5 and the components BC, pOC and SOA were stronger in areas with lower SES.

Conclusion: Our results suggest that exposure to air pollution during the first three years of life may increase the risk for asthma in early childhood. The findings further imply a possible increased vulnerability to air pollutionattributed asthma among low SES children.

Place, publisher, year, edition, pages
Elsevier, 2021
Keywords
Air pollution, Asthma, Pediatric asthma, Socio-economy, Environmental medicine
National Category
Occupational Health and Environmental Health
Identifiers
urn:nbn:se:umu:diva-187363 (URN)10.1016/j.envint.2021.106667 (DOI)000679253400005 ()34077855 (PubMedID)2-s2.0-85111037041 (Scopus ID)
Funder
NordForsk, 75007Swedish Research Council Formas, 2017-00898
Available from: 2021-09-10 Created: 2021-09-10 Last updated: 2021-09-10Bibliographically approved
Öhrn, M., Wahlström, V., Harder, M. S., Nordin, M., Pettersson-Strömbäck, A., Bodin Danielsson, C., . . . Slunga Järvholm, L. (2021). Productivity, Satisfaction, Work Environment and Health after Relocation to an Activity-Based Flex Office: The Active Office Design Study. International Journal of Environmental Research and Public Health, 18(14), Article ID 7640.
Open this publication in new window or tab >>Productivity, Satisfaction, Work Environment and Health after Relocation to an Activity-Based Flex Office: The Active Office Design Study
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2021 (English)In: International Journal of Environmental Research and Public Health, ISSN 1661-7827, E-ISSN 1660-4601, Vol. 18, no 14, article id 7640Article in journal (Refereed) Published
Abstract [en]

Implementation of activity-based flex offices (AFOs) are becoming increasingly common. The aim of this study was to evaluate the effects of an AFO on perceived productivity, satisfaction, work environment and health. Questionnaire data from the longitudinal, quasi-experimental Active Office Design Study was used. The study evaluates a public organization relocating staff to either an AFO or to cell offices. Measures from baseline, 6 and 18 months after relocation, were analyzed. Employees in the AFO experienced a decreased productivity and satisfaction with the office design. Lack of privacy as well as increased noise disturbance, less satisfaction with sit comfort and work posture were reported. Employees in the AFO with work tasks requiring a high degree of concentration experienced lower productivity while those with a high proportion of teamwork rated productivity to be continually high. No significant group differences were found between the two office types in general health, cognitive stress, salutogenic health indicators or pain in the neck, shoulder or back. The study highlights the importance of taking work characteristics into account in the planning and implementation process of an AFO. Flexible and interactive tasks seem more appropriate in an AFO, whereas individual tasks demanding concentration seem less fit.

Place, publisher, year, edition, pages
MDPI, 2021
Keywords
activity-based work, job performance, longitudinal study, new ways of working, occupational health, office worker
National Category
Occupational Health and Environmental Health Architecture
Identifiers
urn:nbn:se:umu:diva-186923 (URN)10.3390/ijerph18147640 (DOI)000676147300001 ()34300090 (PubMedID)2-s2.0-85110122622 (Scopus ID)
Available from: 2021-08-26 Created: 2021-08-26 Last updated: 2021-08-27Bibliographically approved
Ekland, J., Olsson, D., Forsberg, B., Andersson, C. & Orru, H. (2021). The effect of current and future maternal exposure to near-surface ozone on preterm birth in 30 European countries: an EU-wide health impact assessment. Environmental Research Letters, 16(5), Article ID 055005.
Open this publication in new window or tab >>The effect of current and future maternal exposure to near-surface ozone on preterm birth in 30 European countries: an EU-wide health impact assessment
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2021 (English)In: Environmental Research Letters, E-ISSN 1748-9326, Vol. 16, no 5, article id 055005Article in journal (Refereed) Published
Abstract [en]

Preterm birth is the largest contributor to neonatal mortality globally and it is also associated with several adverse health outcomes. Recent studies have found an association between maternal exposure to air pollution and an increased risk for preterm birth. As a constituent of air pollution, ozone is a highly reactive molecule with several negative health effects when present near earth's surface. This health impact assessment aims to estimate the proportion of preterm births - in current and future situations - attributable to maternal ozone exposure in 30 European countries (EU30). A literature search was performed using relevant keywords, followed by meta-analysis with STATA software in which five studies investigating exposure-response relationship of interest were included. The attributable proportion, and number of cases, was modelled with the software AirQ+ against current and future European ozone concentrations. According to our meta-analysis, the relative risk for giving birth preterm was calculated to 1.027 (95% CI 1.009-1.046) per 10 μg m-3 increase in ozone concentration. This rendered 7.1% (95% CI 2.5-11.7) of preterm births attributable to maternal ozone exposure to in EU30 during 2010, which is equal to approximately 27 900 cases. By 2050, the projected decrease in ozone precursor emissions rendered an estimated 30% decrease of ozone attributable preterm births. Not taking emission change into account, due to climate change the ozone-related preterm birth burden might slightly increase by 2050 in Central and Southern Europe, and decrease in Eastern and Northern Europe. In summation, these numbers make a substantial impact on public health.

Place, publisher, year, edition, pages
Institute of Physics Publishing (IOPP), 2021
Keywords
air pollution, children, climate change, emissions, preterm birth
National Category
Occupational Health and Environmental Health
Identifiers
urn:nbn:se:umu:diva-183126 (URN)10.1088/1748-9326/abe6c4 (DOI)000641837700001 ()2-s2.0-85104926244 (Scopus ID)
Available from: 2021-05-18 Created: 2021-05-18 Last updated: 2024-01-17Bibliographically approved
Olsson, D., Johansson, C. & Forsberg, B. (2020). Associations between Vehicle Exhaust Particles and Ozone at Home Address and Birth Weight. International Journal of Environmental Research and Public Health, 17(11), Article ID 3836.
Open this publication in new window or tab >>Associations between Vehicle Exhaust Particles and Ozone at Home Address and Birth Weight
2020 (English)In: International Journal of Environmental Research and Public Health, ISSN 1661-7827, E-ISSN 1660-4601, Vol. 17, no 11, article id 3836Article in journal (Refereed) Published
Abstract [en]

We have studied the associations between exhaust particles and birth weight. Adjustments were made for ozone and potential confounding factors at the individual level. The study included all singletons conceived between August 2003 and February 2013 with mothers living in Greater Stockholm. We obtained record-based register data from the Swedish Medical Birth Register. Data concerning the parents were provided by Statistics Sweden. Exposure levels for nearly 187,000 pregnancies were calculated using a validated air quality dispersion model with input from a detailed emission database. A higher socioeconomic status was associated with higher levels of exhaust particles at the home address. In this region, with rather low air pollution levels, the associations between levels of exhaust particles and birth weight were negative for all three of the studied exposure windows (i.e., first and second trimester and full pregnancy). For the entire pregnancy, the linear decrease in birth weight was 7.5 grams (95% CI-12.0; -2.9) for an increase in exposure, corresponding to the inter quartile range (IQR = 209 ng/m3). We also found that the risk of being born small for gestational age increased with the level of exhaust particles in all three exposure windows, but these associations were not statistically significant.

Place, publisher, year, edition, pages
MDPI, 2020
Keywords
birth weight, environmental epidemiology, traffic pollution
National Category
Occupational Health and Environmental Health
Identifiers
urn:nbn:se:umu:diva-171641 (URN)10.3390/ijerph17113836 (DOI)000542629600089 ()32481677 (PubMedID)2-s2.0-85085678063 (Scopus ID)
Funder
NordForsk, 75007
Available from: 2020-06-08 Created: 2020-06-08 Last updated: 2023-03-24Bibliographically approved
Pettersson, H., Olsson, D. & Järvholm, B. (2020). Occupational exposure to noise and cold environment and the risk of death due to myocardial infarction and stroke. International Archives of Occupational and Environmental Health, 93(5), 571-575
Open this publication in new window or tab >>Occupational exposure to noise and cold environment and the risk of death due to myocardial infarction and stroke
2020 (English)In: International Archives of Occupational and Environmental Health, ISSN 0340-0131, E-ISSN 1432-1246, Vol. 93, no 5, p. 571-575Article in journal (Refereed) Published
Abstract [en]

PURPOSE: The present study examined a possible association between occupational exposure to noise, working and living in cold conditions, and the risk of mortality in myocardial infarction and stroke.

METHODS: The present cohort study consists of 194,501 workers in the Swedish construction industry that participated in health examinations between 1971 and 1993. Noise exposure was defined on a job-exposure matrix based on a survey of the working conditions carried out during the mid 1970s. All workers were categorised into three main regions of Sweden, differing in temperature: Reference (Götaland), colder (Svealand), and coldest (Norrland). Relative risks (RR) were analysed by negative binomial regression adjusting for age, BMI, and smoking habits.

RESULTS: Moderate and high noise exposure was associated with increased risk of myocardial infarction (RR 1.10-1.13 with 95% CI over unit) and stroke mortality (RR 1.15 to 1.19 with 95% CI over unit). There was an increased risk for myocardial infarction (RR 1.10, 95% CI 1.01-1.20), but not for stroke mortality (RR 1.09, 95% CI 0.94-1.25) associated with living and working in the coldest region. There was an interaction on the risk of myocardial infarction mortality between different regions and noise exposure (p = 0.016), but not for stroke mortality (p = 0.88).

CONCLUSIONS: The study indicates an interaction between working at hazardous noise levels and living and working in cold conditions for increased mortality in myocardial infarction.

Place, publisher, year, edition, pages
Springer, 2020
Keywords
Cerebrovascular disease, Ischemic heart disease, Mortality, Prospective cohort study, Work environment
National Category
Occupational Health and Environmental Health
Identifiers
urn:nbn:se:umu:diva-167217 (URN)10.1007/s00420-019-01513-5 (DOI)000536364100005 ()31915923 (PubMedID)2-s2.0-85077587840 (Scopus ID)
Funder
AFA Insurance, 150070
Available from: 2020-01-13 Created: 2020-01-13 Last updated: 2020-07-01Bibliographically approved
Wahlström, V., Olsson, D., Öhberg, F., Olsson, T. & Slunga-Järvholm, L. (2020). Underlying Factors Explaining Physical Behaviors among Office Workers-An Exploratory Analysis. International Journal of Environmental Research and Public Health, 17(24), Article ID 9158.
Open this publication in new window or tab >>Underlying Factors Explaining Physical Behaviors among Office Workers-An Exploratory Analysis
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2020 (English)In: International Journal of Environmental Research and Public Health, ISSN 1661-7827, E-ISSN 1660-4601, Vol. 17, no 24, article id 9158Article in journal (Refereed) Published
Abstract [en]

Studies using technical measurements of physical behavior show wide interindividual variations. This study aimed to explore underlying factors related to sitting, standing and walking among office workers. Cross-sectional data for background characteristics, work-related variables, and device-based measures for sitting, standing and walking were collected among office workers in either a cell office or a flex office with activity-based work. Data were analyzed by Factor Analysis of Mixed Data (FAMD) and multiple robust linear regression. The FAMD resulted in the combination of underlying factors describing six character types. The (1) harmonic and healthy, (2) disabled with poor health, (3) manager that spend a lot of time in meetings and has very high workload, (4) engaged with high workload, (5) employee with creative and computer intense work, with high workload and, (6) employee with high BMI with creative and collaborative work. Regression analysis showed that the character type that was "engaged with high workload" sat more and stood less, while the character type with "high BMI and with creative and collaborative work" sat less. The results suggest that physical behavior among office workers is influenced by a complex combination of factors, which should be taken into account in the evaluation of future studies of larger cohorts.

Place, publisher, year, edition, pages
MDPI, 2020
Keywords
occupational health, office design, sedentary behavior, technical measurements, variance, workplace
National Category
Occupational Health and Environmental Health
Identifiers
urn:nbn:se:umu:diva-177992 (URN)10.3390/ijerph17249158 (DOI)000603479100001 ()33302452 (PubMedID)2-s2.0-85097561502 (Scopus ID)
Funder
AFA Insurance, 140308Region Västerbotten
Available from: 2020-12-29 Created: 2020-12-29 Last updated: 2023-03-24Bibliographically approved
Bråbäck, L., Olsson, D. & Forsberg, B. (2019). Grandmaternal smoking during pregnancy and asthma in grandchildren [Letter to the editor]. Journal of Allergy and Clinical Immunology, 144(2), Article ID 624.
Open this publication in new window or tab >>Grandmaternal smoking during pregnancy and asthma in grandchildren
2019 (English)In: Journal of Allergy and Clinical Immunology, ISSN 0091-6749, E-ISSN 1097-6825, Vol. 144, no 2, article id 624Article in journal, Letter (Refereed) Published
National Category
Occupational Health and Environmental Health
Identifiers
urn:nbn:se:umu:diva-162528 (URN)10.1016/j.jaci.2019.03.036 (DOI)000478789300039 ()31213286 (PubMedID)2-s2.0-85069848930 (Scopus ID)
Available from: 2019-08-21 Created: 2019-08-21 Last updated: 2023-03-23Bibliographically approved
Jackson, J. A., Olsson, D., Burdorf, A., Punnett, L., Järvholm, B. & Wahlström, J. (2019). Occupational biomechanical risk factors for radial nerve entrapment in a 13-year prospective study among male construction workers. Occupational and Environmental Medicine, 76(5), 326-331
Open this publication in new window or tab >>Occupational biomechanical risk factors for radial nerve entrapment in a 13-year prospective study among male construction workers
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2019 (English)In: Occupational and Environmental Medicine, ISSN 1351-0711, E-ISSN 1470-7926, Vol. 76, no 5, p. 326-331Article in journal (Refereed) Published
Abstract [en]

OBJECTIVES: The aim was to assess the association between occupational biomechanical exposure and the occurrence of radial nerve entrapment (RNE) in construction workers over a 13-year follow-up period.

METHODS: A cohort of 229 707 male construction workers who participated in a national occupational health surveillance programme (1971-1993) was examined prospectively (2001-2013) for RNE. Height, weight, age, smoking status and job title (construction trade) were obtained on health examination. RNE case status was defined by surgical release of RNE, with data from the Swedish national registry for out-patient surgery records. A job exposure matrix was developed, and biomechanical exposure estimates were assigned according to job title. Highly correlated exposures were summed into biomechanical exposure scores. Negative binomial models were used to estimate the relative risks (RR) (incidence rate ratios) of RNE surgical release for the biomechanical factors and exposure sum scores. Predicted incidence was assessed for each exposure score modelled as a continuous variable to assess exposure-response relationships.

RESULTS: The total incidence rate of surgically treated RNE over the 13-year observation period was 3.53 cases per 100 000 person-years. There were 92 cases with occupational information. Increased risk for RNE was seen in workers with elevated hand-grip forces (RR=1.79, 95% CI 0.97 to 3.28) and exposure to hand-arm vibration (RR=1.47, 95% CI 1.08 to 2.00).

CONCLUSIONS: Occupational exposure to forceful handgrip work and vibration increased the risk for surgical treatment of RNE.

Place, publisher, year, edition, pages
BMJ Publishing Group Ltd, 2019
Keywords
elbow flexion/extension, hand tools, hand-arm vibration, job exposure matrix, nerve entrapment, neuropathy, repetitive, static work, upper extremity load
National Category
Occupational Health and Environmental Health
Identifiers
urn:nbn:se:umu:diva-157109 (URN)10.1136/oemed-2018-105311 (DOI)000471888700007 ()30850390 (PubMedID)2-s2.0-85062728256 (Scopus ID)
Funder
Forte, Swedish Research Council for Health, Working Life and Welfare
Available from: 2019-03-11 Created: 2019-03-11 Last updated: 2023-09-05Bibliographically approved
Organisations
Identifiers
ORCID iD: ORCID iD iconorcid.org/0000-0002-8965-4312

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