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Valid Exposure Protocols Needed in Magnetic Resonance Imaging Genotoxic Research
Umeå universitet, Medicinska fakulteten, Institutionen för strålningsvetenskaper, Radiofysik.ORCID-id: 0000-0002-8377-5703
Umeå universitet, Medicinska fakulteten, Institutionen för strålningsvetenskaper, Radiofysik.ORCID-id: 0000-0003-4084-6652
Umeå universitet, Medicinska fakulteten, Institutionen för strålningsvetenskaper, Radiofysik.ORCID-id: 0000-0001-7260-6819
2020 (engelsk)Inngår i: Bioelectromagnetics, ISSN 0197-8462, E-ISSN 1521-186X, Vol. 41, nr 3, s. 247-257Artikkel i tidsskrift, Letter (Fagfellevurdert) Published
Abstract [en]

Several in vitro and in vivo studies have investigated if a magnetic resonance imaging (MRI) examination can cause DNA damage in human blood cells. However, the electromagnetic field (EMF) exposure that the cells received in the MR scanner was not sufficiently described. The first studies looking into this could be regarded as hypothesis-generating studies. However, for further exploration into the role of MRI exposure on DNA integrity, the exposure itself cannot be ignored. The lack of sufficient method descriptions makes the early experiments difficult, if not impossible, to repeat. The golden rule in all experimental work is that a study should be repeatable by someone with the right knowledge and equipment, and this is simply not the case with many of the recent studies on MRI and genotoxicity. Here we discuss what is lacking in previous studies, and how we think the next generation of in vitro and in vivo studies on MRI and genotoxicity should be performed. Bioelectromagnetics.

sted, utgiver, år, opplag, sider
WILEY , 2020. Vol. 41, nr 3, s. 247-257
Emneord [en]
DNA, magnetic field, pulse sequence, isocenter, genotoxicity
HSV kategori
Identifikatorer
URN: urn:nbn:se:umu:diva-169358DOI: 10.1002/bem.22257ISI: 000519338000008PubMedID: 32157722Scopus ID: 2-s2.0-85081679643OAI: oai:DiVA.org:umu-169358DiVA, id: diva2:1422397
Tilgjengelig fra: 2020-04-07 Laget: 2020-04-07 Sist oppdatert: 2023-03-24bibliografisk kontrollert

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