Partnership signifies a key transition for social recognition in society. This study identifies long-term trends of disability and partnership in Sweden evidenced by the chances to marry or cohabit during two centuries (1800s–2010s). We compare results from studies within one comprehensive disability project, making use of quantitative life-course analysis and population records. Our findings uncover a remarkably persistent trend from the 1800s until the 2010s. Disability impeded both men and women’s partnership chances significantly (by about 60%), with some variations across disability types, genders, and periods. That disabled people did not enjoy greater access to a partner relative to others while Sweden moved from a poor country to a wealthy welfare state, suggests that disability persistently affords fewer possibilities to participate in social life and society. Our study is exceptional by combining disability with partnership and comparing recent results with the past.