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Long-term health outcomes from inbreeding in a historical Swedish population: longevity, fertility, and impairments
Umeå universitet, Samhällsvetenskapliga fakulteten, Enheten för demografi och åldrandeforskning (CEDAR).ORCID-id: 0000-0002-1561-4094
Umeå universitet, Humanistiska fakulteten, Institutionen för idé- och samhällsstudier. Umeå universitet, Samhällsvetenskapliga fakulteten, Enheten för demografi och åldrandeforskning (CEDAR). (DISTIME)ORCID-id: 0000-0001-9042-9166
2024 (engelsk)Inngår i: Annals of Human Biology, ISSN 0301-4460, E-ISSN 1464-5033, Vol. 51, nr 1, artikkel-id 2369281Artikkel i tidsskrift (Fagfellevurdert) Published
Abstract [en]

Background: Inbreeding, arising from consanguinity between related parents, has been observed to impact the health of individuals, typically attributed to biological factors. Nevertheless, these effects may be influenced by the social and environmental conditions. The prevalence of consanguineous marriages increased in certain parts of Sweden after it became legal in 1844, which offers a unique opportunity to study and understand the effects of inbreeding on health.

Aim: The objective of this study is to explore the potential impact of inbreeding on the longevity, fertility, and impairments of individuals born in the Skellefteå region, Sweden, between 1890 and 1905, with a follow-up period extending until 1950.

Subjects and methods: The level of inbreeding is calculated using micro-level parish register data and related to longevity, fertility, and impairments using regression analysis.

Results: Inbreeding is shown to be associated with longevity, fertility, and impairments. It seems to affect the risk of stillbirth and impairments and male longevity and fertility.

Conclusion: Inbreeding seems to have had a detrimental effect on some health outcomes in this historical population under study.

sted, utgiver, år, opplag, sider
Taylor & Francis, 2024. Vol. 51, nr 1, artikkel-id 2369281
Emneord [en]
Human inbreeding, consanguinity, fertility, impairment, longevity
HSV kategori
Forskningsprogram
befolkningsstudier
Identifikatorer
URN: urn:nbn:se:umu:diva-227799DOI: 10.1080/03014460.2024.2369281ISI: 001268150500001PubMedID: 38979927Scopus ID: 2-s2.0-85198302674OAI: oai:DiVA.org:umu-227799DiVA, id: diva2:1883287
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DISTIMEDISLIFE
Forskningsfinansiär
Marcus and Amalia Wallenberg Foundation, 2019.0003EU, European Research Council, 647125Tilgjengelig fra: 2024-07-09 Laget: 2024-07-09 Sist oppdatert: 2025-02-20bibliografisk kontrollert

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Häggström Gunfridsson, ErlingVikström, Lotta

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