3D spheroid and organoid models to study neuroinfection of RNA virusesVise andre og tillknytning
2024 (engelsk)Inngår i: Rift Valley Fever Virus: methods and protocols / [ed] Pierre-Yves Lozach, Humana Press, 2024, , s. 16s. 409-424Kapittel i bok, del av antologi (Fagfellevurdert)
Abstract [en]
Three-dimensional culture models of the brain enable the study of neuroinfection in the context of a complex interconnected cell matrix. Depending on the differentiation status of the neural cells, two models exist: 3D spheroids also called neurospheres and cerebral organoids. Here, we describe the preparation of 3D spheroids and cerebral organoids and give an outlook on their usage to study Rift Valley fever virus and other neurotropic viruses.
sted, utgiver, år, opplag, sider
Humana Press, 2024. , s. 16s. 409-424
Serie
Methods in Molecular Biology (MIMB), ISSN 1064-3745, E-ISSN 1940-6029 ; 2824
Emneord [en]
3D spheroid, Cerebral organoid, Induced pluripotent stem cells, Neural progenitor cells, Neuroinfection, Neurosphere, Neurotropic virus
HSV kategori
Identifikatorer
URN: urn:nbn:se:umu:diva-228953DOI: 10.1007/978-1-0716-3926-9_26Scopus ID: 2-s2.0-85201261011ISBN: 9781071639252 (tryckt)ISBN: 9781071639283 (tryckt)ISBN: 9781071639269 (digital)OAI: oai:DiVA.org:umu-228953DiVA, id: diva2:1893750
2024-08-302024-08-302024-08-30bibliografisk kontrollert