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How do microbes evade neutrophil killing?
Umeå universitet, Medicinska fakulteten, Molekylär Infektionsmedicin, Sverige (MIMS). Umeå universitet, Medicinska fakulteten, Institutionen för molekylärbiologi (Medicinska fakulteten).
2006 (engelsk)Inngår i: Cellular Microbiology, ISSN 1462-5814, E-ISSN 1462-5822, Vol. 8, nr 11, s. 1687-1696Artikkel i tidsskrift (Fagfellevurdert) Published
Abstract [en]

Many microbial pathogens evolved to circumvent the attack of neutrophils, which are essential effector cells of the innate immune system. Here we review six major strategies that pathogenic bacteria and fungi use to evade neutrophil defences: (i) turning on survival and stress responses, (ii) avoiding contact, (iii) preventing phagocytosis, (iv) surviving intracellularly, (v) inducing cell death and (vi) evading killing by neutrophil extracellular traps. For each category we give examples and further focus on one particular pathogenic microbe in more detail. Pathogens include Candida albicans, Cryptococcus neoformans, Yersinia ssp., Helicobacter pylori, Staphylococcus aureus, Streptococcus pyogenes and Streptococcus pneumoniae.

sted, utgiver, år, opplag, sider
Blackwell Publishing, 2006. Vol. 8, nr 11, s. 1687-1696
HSV kategori
Identifikatorer
URN: urn:nbn:se:umu:diva-32552DOI: 10.1111/j.1462-5822.2006.00792.xISI: 000241191200001PubMedID: 16939535OAI: oai:DiVA.org:umu-32552DiVA, id: diva2:304076
Tilgjengelig fra: 2010-03-16 Laget: 2010-03-16 Sist oppdatert: 2019-01-23bibliografisk kontrollert

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