Chronic airway obstruction in a population-based adult asthma cohort: Prevalence, incidence and prognostic factorsShow others and affiliations
2018 (English)In: Respiratory Medicine, ISSN 0954-6111, E-ISSN 1532-3064, Vol. 138, p. 115-122Article in journal (Refereed) Published
Abstract [en]
BACKGROUND: Asthma and COPD may overlap (ACO) but information about incidence and risk factors are lacking. This study aimed to estimate prevalence, incidence and risk factors of chronic airway obstruction (CAO) in a population-based adult asthma cohort.
METHODS: /FVC<0.7.
RESULTS: decline and higher levels of neutrophils than asthma only. Smoking, older age and male sex were independently associated with increased risk for both prevalent and incident CAO, while obesity had a protective effect.
CONCLUSIONS: In this prospective adult asthma cohort, the majority did not develop CAO. Smoking, older age and male sex were risk factors for prevalent and incident CAO, similar to risk factors described for COPD in the general population.
Place, publisher, year, edition, pages
W.B. Saunders Ltd , 2018. Vol. 138, p. 115-122
Keywords [en]
ACO, Asthma, Epidemiology, Longitudinal study, Risk factors
National Category
Respiratory Medicine and Allergy
Identifiers
URN: urn:nbn:se:umu:diva-147915DOI: 10.1016/j.rmed.2018.03.036ISI: 000432442400017PubMedID: 29724382Scopus ID: 2-s2.0-85045212522OAI: oai:DiVA.org:umu-147915DiVA, id: diva2:1209150
2018-05-222018-05-222023-03-24Bibliographically approved