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Epidemiology of fungaemia in Sweden: a nationwide retrospective observational survey
Vise andre og tillknytning
2018 (engelsk)Inngår i: Mycoses, ISSN 0933-7407, E-ISSN 1439-0507, Vol. 61, nr 10, s. 777-785Artikkel i tidsskrift (Fagfellevurdert) Published
Abstract [en]

Objectives:

To identify the epidemiology and antifungal susceptibilities of Candida spp. among blood culture isolates to identify the epidemiology and antifungal susceptibilities of Candida spp. among blood culture isolates in Sweden.

Methods: The study was a retrospective, observational nationwide laboratory-based surveillance for fungaemia and fungal meningitis and was conducted from September 2015 to August 2016.

Results: In total, 488 Candida blood culture isolates were obtained from 471 patients (58% males). Compared to our previous study, the incidence of candidaemia has increased from 4.2/100000 (2005-2006) to 4.7/100000 population/year (2015-2016). The three most common Candida spp. isolated from blood cultures were Candida albicans (54.7%), Candida glabrata (19.7%) and species in the Candida parapsilosis complex (9.4%). Candida resistance to fluconazole was 2% in C.albicans and between 0% and 100%, in non-albicans species other than C.glabrata and C.krusei. Resistance to voriconazole was rare, except for C.glabrata, C.krusei and C.tropicalis. Resistance to anidulafungin was 3.8% while no Candida isolate was resistant to amphotericin B.

Conclusions: We report an overall increase in candidaemia but a minor decrease of C.albicans while C.glabrata and C.parapsilosis remain constant over this 10-year period.

sted, utgiver, år, opplag, sider
Wiley-Blackwell, 2018. Vol. 61, nr 10, s. 777-785
Emneord [en]
antifungal susceptibility, Candida, candidaemia, Cryptococcus, fungaemia epidemiology, fungal meningitis epidemiology, incidence
HSV kategori
Identifikatorer
URN: urn:nbn:se:umu:diva-153718DOI: 10.1111/myc.12816ISI: 000445333300010PubMedID: 29920785Scopus ID: 2-s2.0-85050680986OAI: oai:DiVA.org:umu-153718DiVA, id: diva2:1266234
Tilgjengelig fra: 2018-11-27 Laget: 2018-11-27 Sist oppdatert: 2023-03-24bibliografisk kontrollert

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