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The cost-effectiveness of treatments for attention deficit-hyperactivity disorder and autism spectrum disorder in children and adolescents: a systematic review
Department of Public Health and Caring Sciences, Uppsala University, Uppsala, Sweden.
Umeå University, Faculty of Medicine, Department of Epidemiology and Global Health. Department of Public Health and Caring Sciences, Uppsala University, Uppsala, Sweden.
Center for the Evaluation of Value and Risk, Institute for Clinical Research and Health Policy Studies, Tufts Medical Center, MA, Boston, United States.
Regional Centre for Child and Youth Mental Health and Child Welfare, IPH, Faculty of Medicine and Health Sciences, Norwegian University of Science and Technology, Trondheim, Norway; Child and Adolescent Mental Health Services, St. Olav Hospital, Trondheim, Norway.
2022 (English)In: European Child and Adolescent Psychiatry, ISSN 1018-8827, E-ISSN 1435-165X, Vol. 31, p. 1655-1670Article, review/survey (Refereed) Published
Abstract [en]

Economic evaluations can help decision makers identify what services for children with neurodevelopmental disorders provide best value-for-money. The aim of this paper is to review the best available economic evidence to support decision making for attention deficit-hyperactivity disorder (ADHD) and autism spectrum disorder (ASD) in children and adolescents. We conducted a systematic review of economic evaluations of ADHD and ASD interventions including studies published 2010–2020, identified through Econlit, Medline, PsychINFO, and ERIC databases. Only full economic evaluations comparing two or more options, considering both costs and consequences were included. The quality of the studies was assessed using the Drummond checklist. We identified ten studies of moderate-to-good quality on the cost-effectiveness of treatments for ADHD and two studies of good quality of interventions for ASD. The majority of ADHD studies evaluated pharmacotherapy (n = 8), and two investigated the economic value of psychosocial/behavioral interventions. Both economic evaluations for ASD investigated early and communication interventions. Included studies support the cost-effectiveness of behavioral parenting interventions for younger children with ADHD. Among pharmacotherapies for ADHD, different combinations of stimulant/non-stimulant medications for children were cost-effective at willingness-to-pay thresholds reported in the original papers. Early intervention for children with suspected ASD was cost-effective, but communication-focused therapy for preschool children with ASD was not. Prioritizing more studies in this area would allow decision makers to promote cost-effective and clinically effective interventions for this target group.

Place, publisher, year, edition, pages
Springer, 2022. Vol. 31, p. 1655-1670
Keywords [en]
Attention deficit-hyperactivity disorder, Autism spectrum disorder, Cost-effectiveness analysis, Intervention, Neurodevelopmental disorders, Treatment
National Category
Psychiatry Pediatrics
Identifiers
URN: urn:nbn:se:umu:diva-181648DOI: 10.1007/s00787-021-01748-zISI: 000626857700002PubMedID: 33751229Scopus ID: 2-s2.0-85102335990OAI: oai:DiVA.org:umu-181648DiVA, id: diva2:1564414
Available from: 2021-06-11 Created: 2021-06-11 Last updated: 2022-12-30Bibliographically approved

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Feldman, Inna

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CiteExportLink to record
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