This article explores the political space of the border through the experiences of Myanmar women activists, for whom the borderlands in Thailand have provided refuge as well as a conducive environment for political mobilization. At the same time, the border renders refugee activists insecure and precarious. Drawing on life history interviews, our analysis expands conceptualizations of the border as a dynamic political space by illustrating its dual capacity to both facilitate and constrain the political agency of refugee women from Myanmar. In particular, the spatial and temporal fluidity and in-betweenness of the border is shown to foster both repression and resistance. Exploring the character and salience of the border as a space for activism over time, we demonstrate how the political space of the border is relational, constituted in interaction with other political spaces, such as politics and governance in Myanmar, transnational activist networks, and the politics of international aid.