Umeå University's logo

umu.sePublications
Change search
CiteExportLink to record
Permanent link

Direct link
Cite
Citation style
  • apa
  • ieee
  • modern-language-association-8th-edition
  • vancouver
  • Other style
More styles
Language
  • de-DE
  • en-GB
  • en-US
  • fi-FI
  • nn-NO
  • nn-NB
  • sv-SE
  • Other locale
More languages
Output format
  • html
  • text
  • asciidoc
  • rtf
Outcomes of iStent inject versus kahook dual blade surgery in glaucoma patients undergoing cataract surgery
Umeå University, Faculty of Medicine, Department of Clinical Sciences, Ophthalmology.ORCID iD: 0000-0001-6025-2523
Division of Ophthalmology and Vision, Department of Clinical Neuroscience, Karolinska Institutet, Stockholm, Sweden; Department of Ophthalmology, Capio Sophiahemmet Hospital, Stockholm, Sweden.
Umeå University, Faculty of Medicine, Wallenberg Centre for Molecular Medicine at Umeå University (WCMM). Umeå University, Faculty of Medicine, Department of Clinical Sciences, Ophthalmology. Department of Ophthalmology, University of Iceland, Reykjavik, Iceland.ORCID iD: 0000-0003-0218-4563
2023 (English)In: Journal of glaucoma, ISSN 1057-0829, E-ISSN 1536-481X, Vol. 32, no 10, p. e121-e128Article in journal (Refereed) Published
Abstract [en]

Précis: iStent Inject implantation (iStent) or Kahook Dual Blade goniotomy (KDB) in combination with phacoemulsification have a similar IOP-lowering effect in all stages of glaucoma, and medications are significantly reduced, especially after KDB.

PURPOSE: To compare the 2-year efficacy and safety of iStent or KDB in combination with phacoemulsification in eyes with mild to advanced open angle glaucoma.

METHODS: A retrospective chart review of 153 patients that received iStent or KDB in combination with phacoemulsification at a single center between March 2019 and August 2020. The main outcome parameters at 2 years were: (1) intraocular pressure (IOP)-reduction ≥20%, with a postoperative IOP ≤18 mm Hg, and (2) a reduction of ≥1 medication. Results were stratified by glaucoma grade.

RESULTS: After 2 years, mean IOP was reduced from 20.3±6.1 to 14.2±4.1 mm Hg in the phaco-iStent group ( P <0.001) and from 20.1±6.1 to 14.7±3.6 mm Hg in the phaco-KDB group ( P <0.001). The mean number of medications was reduced from 3.0±0.9 to 2.6±1.1 in the Phaco-iStent group ( P =0.001) and from 2.3±1.0 to 1.5±1.3 in the Phaco-KDB group ( P <0.001). Success regarding IOP-reduction ≥20% with a postoperative IOP ≤18 mm Hg was met by 46% in the phaco-iStent group and by 51% in the phaco-KDB group. A reduction of ≥1 medication was met by 32% in the phaco-iStent group and by 53% in the phaco-KDB group ( P =0.013). Eyes with mild to moderate and advanced glaucoma responded equally well to the success criteria.

CONCLUSIONS: iStent and KDB, in combination with phacoemulsification, both lowered IOP effectively in all stages of glaucoma. More medications were reduced after KDB, suggesting that it may be a more effective procedure compared with iStent.

Place, publisher, year, edition, pages
Wolters Kluwer, 2023. Vol. 32, no 10, p. e121-e128
National Category
Ophthalmology
Identifiers
URN: urn:nbn:se:umu:diva-215079DOI: 10.1097/IJG.0000000000002243PubMedID: 37327470Scopus ID: 2-s2.0-85172940680OAI: oai:DiVA.org:umu-215079DiVA, id: diva2:1804670
Funder
Region Jämtland HärjedalenRegion VästerbottenKnut and Alice Wallenberg FoundationAvailable from: 2023-10-13 Created: 2023-10-13 Last updated: 2024-01-15Bibliographically approved

Open Access in DiVA

fulltext(348 kB)139 downloads
File information
File name FULLTEXT01.pdfFile size 348 kBChecksum SHA-512
cb0504bed5fa0ed3e274803ba29a2807118e195c6a360e2849bf1011a90c9d9e7dbbd8c1389704bf05bf11cc2c776ef7718721b6f701495a351383e61f47ac7e
Type fulltextMimetype application/pdf

Other links

Publisher's full textPubMedScopus

Authority records

Barkander, AnnaJóhannesson, Gauti

Search in DiVA

By author/editor
Barkander, AnnaJóhannesson, Gauti
By organisation
OphthalmologyWallenberg Centre for Molecular Medicine at Umeå University (WCMM)
In the same journal
Journal of glaucoma
Ophthalmology

Search outside of DiVA

GoogleGoogle Scholar
Total: 139 downloads
The number of downloads is the sum of all downloads of full texts. It may include eg previous versions that are now no longer available

doi
pubmed
urn-nbn

Altmetric score

doi
pubmed
urn-nbn
Total: 283 hits
CiteExportLink to record
Permanent link

Direct link
Cite
Citation style
  • apa
  • ieee
  • modern-language-association-8th-edition
  • vancouver
  • Other style
More styles
Language
  • de-DE
  • en-GB
  • en-US
  • fi-FI
  • nn-NO
  • nn-NB
  • sv-SE
  • Other locale
More languages
Output format
  • html
  • text
  • asciidoc
  • rtf