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Fluoride releasing in polymerblends of poly(ethylene oxide) and poly(methyl methacrylate)
Umeå universitet, Medicinska fakulteten, Institutionen för odontologi.
Umeå universitet, Medicinska fakulteten, Institutionen för odontologi.
Umeå universitet, Medicinska fakulteten, Institutionen för odontologi.
Umeå universitet, Medicinska fakulteten, Institutionen för odontologi.ORCID-id: 0000-0002-1710-7715
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2024 (engelsk)Inngår i: Frontiers in Chemistry, E-ISSN 2296-2646, Vol. 12, artikkel-id 1356029Artikkel i tidsskrift (Fagfellevurdert) Published
Abstract [en]

Introduction: Polymethyl methacrylate is a polymer commonly used in clinicaldentistry, including denture bases, occlusal splints and orthodontic retainers.

Methods: To augment the polymethyl methacrylate-based dental appliances incounteracting dental caries, we designed a polymer blend film composed ofpolymethyl methacrylate and polyethylene oxide by solution casting and addedsodium fluoride.

Results: Polyethylene oxide facilitated the dispersion of sodium fluoride,decreased the surface average roughness, and positively influenced thehydrophilicity of the films. The blend film made of polymethyl methacrylate,polyethylene oxide and NaF with a mass ratio of 10: 1: 0.3 showed sustainedrelease of fluoride ions and acceptable cytotoxicity. Antibacterial activity of all thefilms to Streptococcus mutans was negligible.

Discussion: This study demonstrated that the polymer blends of polyethyleneoxide and polymethyl methacrylate could realize the relatively steady release offluoride ions with high biocompatibility. This strategy has promising potential toendow dental appliances with anti-cariogenicity.

sted, utgiver, år, opplag, sider
Frontiers Media S.A., 2024. Vol. 12, artikkel-id 1356029
Emneord [en]
dental materials, polymethyl methacrylate, polyethylene oxide, fluoride ion release, polymer blend
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Identifikatorer
URN: urn:nbn:se:umu:diva-220718DOI: 10.3389/fchem.2024.1356029Scopus ID: 2-s2.0-85185521631OAI: oai:DiVA.org:umu-220718DiVA, id: diva2:1836516
Forskningsfinansiär
Region Västerbotten, RV-937838The Kempe Foundations, JCSMK22-0122The Kempe Foundations, SMK-21-0015Swedish Research Council, 2021-04778Swedish Research Council, 2020-04437Tilgjengelig fra: 2024-02-09 Laget: 2024-02-09 Sist oppdatert: 2024-02-29bibliografisk kontrollert

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Wang, TianxiaoLi, MenghongGu, ZiyanQu, ChengjuanSegervald, JonasSalh, RoushdeyWågberg, ThomasWang, JiaKou, Wen

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Wang, TianxiaoLi, MenghongGu, ZiyanQu, ChengjuanSegervald, JonasSalh, RoushdeyWågberg, ThomasWang, JiaKou, Wen
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