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Can our experience with surveillance for inherited pancreatic cancer help to identify early pancreatic cancer in the general population?
Karolinska Comprehensive Cancer Center and Karolinska Institutet, Stockholm, Sweden; Div. of Surgery & amp; Oncology, Dept. of Upper Abdominal Diseases, CLINTEC Karolinska Institutet, Karolinska Comprehensive Cancer Center, Stockholm, Sweden.
Umeå University, Faculty of Medicine, Department of Radiation Sciences. Umeå University, Faculty of Medicine, Wallenberg Centre for Molecular Medicine at Umeå University (WCMM).ORCID iD: 0000-0002-5847-2778
Department of Learning, Informatics, Management and Ethics (LIME), Karolinska Institutet, Stockholm, Sweden.
Karolinska Comprehensive Cancer Center and Karolinska Institutet, Stockholm, Sweden.
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2024 (English)In: Familial Cancer, ISSN 1389-9600, E-ISSN 1573-7292Article, review/survey (Refereed) Epub ahead of print
Abstract [en]

Screening of the general population for cancer is a matter of primary prevention reducing the burden of disease. Whilst this is successful for several cancers including breast, colon and prostate, the situation to screen and hence prevent pancreatic cancer is different. The organ is not as accessible to simple physical exam or biological samples (fecal or blood test). Neither exists a blood test such as PSA that is cost-effective. Reviewing the evidence from screening risk groups for pancreatic cancer, one must conclude that there is no rational at present to screen the general population, for a lack of appropriate tests.

Place, publisher, year, edition, pages
Springer Nature, 2024.
Keywords [en]
General population, Incidental finding, Individuals at risk, Pancreatic cancer, Screening, Surveillance
National Category
Cancer and Oncology
Identifiers
URN: urn:nbn:se:umu:diva-222299DOI: 10.1007/s10689-024-00363-6ISI: 001174923700001PubMedID: 38441833Scopus ID: 2-s2.0-85186597174OAI: oai:DiVA.org:umu-222299DiVA, id: diva2:1844513
Funder
Signe and Olof Wallenius FoundationSwedish Cancer Society, 21 1585Swedish Cancer Society, 22 2318Swedish Cancer Society, 19 0273Swedish Cancer Society, 2011/1110Swedish Cancer Society, 2016/634Swedish Cancer Society, 2017/332Swedish Cancer Society, 2017/827Swedish Cancer Society, 20 1339Swedish Research Council, 2016–02990Swedish Research Council, 2019−01690Region Västerbotten, 583411Region Västerbotten, RV-583411Region Västerbotten, RV-549731Region Västerbotten, RV-841551Region Västerbotten, RV-930478Region Västerbotten, RV-930132Region Västerbotten, RV-99607108Region Västerbotten, RV-9960708Region Västerbotten, VLL-837731Region Västerbotten, RV-930167Region Västerbotten, VLL- 643451Region Västerbotten, RV-978812Sjöberg FoundationKnut and Alice Wallenberg FoundationMarianne and Marcus Wallenberg FoundationAvailable from: 2024-03-14 Created: 2024-03-14 Last updated: 2024-03-14Bibliographically approved

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Öhlund, DanielSund, Malin

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Department of Radiation SciencesWallenberg Centre for Molecular Medicine at Umeå University (WCMM)Surgery
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