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Level of education modifies asthma mortality in Norway and Sweden. The Nordic EpiLung study
Umeå University, Faculty of Medicine, Department of Public Health and Clinical Medicine, Section of Sustainable Health.ORCID iD: 0000-0002-0553-8067
K.G. Jebsen Center for Genetic Epidemiology, Department of Public Health and Nursing, Faculty of Medicine and Health Sciences, Norwegian University of Science and Technology NTNU, Trondheim, Norway; Division of Mental Health Care, St. Olavs Hospital, Trondheim University Hospital, Trondheim, Norway.
Umeå University, Faculty of Medicine, Department of Public Health and Clinical Medicine, Section of Sustainable Health.ORCID iD: 0000-0002-1630-3167
K.G. Jebsen Center for Genetic Epidemiology, Department of Public Health and Nursing, Faculty of Medicine and Health Sciences, Norwegian University of Science and Technology NTNU, Trondheim, Norway.
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2024 (English)In: Journal of Asthma and Allergy, ISSN 1178-6965, Vol. 17, p. 209-218Article in journal (Refereed) Published
Abstract [en]

Background and Aim: The relationship between socioeconomic status (SES), asthma and mortality is complex and multifaceted, and it is not established if educational level modifies the association between asthma and mortality. The aim was to study the association between asthma and mortality in Sweden and Norway and to what extent educational level modifies this association.

Participants and Methods: Within the Nordic EpiLung Study, >56,000 individuals aged 30–69 years participated in population-based surveys on asthma and associated risk factors in Sweden and Norway during 2005–2007. Data on educational level and 10-year all-cause mortality were linked by national authorities. The fraction of mortality risk attributable to asthma was calculated, and Cox regression was used to estimate hazard ratios (HR) and 95% confidence intervals (95% CI) for mortality related to asthma, stratified by educational level.

Results: In total, 5.5% of all deaths was attributed to asthma. When adjusted for potential confounders, the HR for mortality related to asthma was 1.71 (95% CI 1.52–1.93). Those with primary level of education had higher hazard of all-cause death related to asthma than those with tertiary level (HR 1.80, 95% CI 1.48–2.18, vs HR 1.39, 95% CI 0.99–1.95).

Conclusion: Asthma was associated with an overall 71% increased all-cause mortality and 5.5% of deaths can be attributed to asthma. Educational levels modified the risk of mortality associated with asthma, with the highest risk among those with primary education.

Place, publisher, year, edition, pages
Dove Medical Press, 2024. Vol. 17, p. 209-218
Keywords [en]
cohort, epidemiology, prognosis
National Category
Respiratory Medicine and Allergy Public Health, Global Health and Social Medicine
Identifiers
URN: urn:nbn:se:umu:diva-222877DOI: 10.2147/JAA.S450103ISI: 001188357200001PubMedID: 38524102Scopus ID: 2-s2.0-85188309008OAI: oai:DiVA.org:umu-222877DiVA, id: diva2:1851078
Funder
Forte, Swedish Research Council for Health, Working Life and Welfare, Dnr 2022-00381Swedish Research CouncilSwedish Heart Lung FoundationRegion VästerbottenNorrbotten County CouncilSwedish Asthma and Allergy AssociationAvailable from: 2024-04-12 Created: 2024-04-12 Last updated: 2025-02-20Bibliographically approved

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Backman, HelenaHedman, LinneaLindberg, AnneRönmark, Eva

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