Until recently, few have critically examined how power relations and norms concerning disability and ability are depicted and negotiated in science fiction, even though many science fiction narratives seem preoccupied with non-normative bodies and minds. Likewise, in disability studies, the study of non-realist texts and questions of genre are also quite a new field of study. This chapter suggests ways in which the study of science fiction could benefit from a disability perspective by outlining some points of contact between disability studies and the study of science fiction. The chapter begins with a short introduction to disability studies and a brief overview of previous research on science fiction and disability. Drawing upon some key themes and issues within this rapidly expanding field of research, the chapter highlights some ways in which a disability perspective can be beneficial for the study of science fiction narratives. First, by applying a critique of the medical model of disability to narratives about the future. Second, reflecting on the importance to consider non-realist elements when reading and analyzing disability in science fiction. For example, by acknowledging not only the explicit presence of (realist) disabled bodies and minds, but also consider how norms and power relations related to ability and disability influence narratives even in absence of such representations.