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Ultra-fast, one-click radiotherapy treatment planning outside a treatment planning system
Department of Radiation Oncology, Medical University of Vienna, Vienna, Australia.
Department of Radiation Oncology, Medical University of Vienna, Vienna, Australia.
Umeå University, Faculty of Medicine, Department of Diagnostics and Intervention.ORCID iD: 0000-0002-8971-9788
Umeå University, Faculty of Medicine, Department of Diagnostics and Intervention.ORCID iD: 0000-0002-6321-8117
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2025 (English)In: Physics and Imaging in Radiation Oncology, E-ISSN 2405-6316, Vol. 33, article id 100724Article in journal (Refereed) Published
Abstract [en]

We present an automated radiation oncology treatment planning pipeline that operates between segmentation and plan review, minimizing manual interaction and reliance on traditional planning systems. Two AI models work in sequence: the first generates a dose distribution, and the second creates a deliverable DICOM-RT plan. Trained and validated on 276 plans, and tested on 151 datasets, the system produced clinically deliverable plans—complete with all VMAT parameters—in about 38 s. These plans met target coverage and most organ-at-risk constraints. This proof-of-concept demonstrates the feasibility of generating high-quality, deliverable DICOM plans within seconds.

Place, publisher, year, edition, pages
Elsevier, 2025. Vol. 33, article id 100724
Keywords [en]
Artificial intelligence, Auto-planning, Automation, Deep learning, Prostate, Treatment planning, VMAT
National Category
Radiology and Medical Imaging Cancer and Oncology
Identifiers
URN: urn:nbn:se:umu:diva-235676DOI: 10.1016/j.phro.2025.100724Scopus ID: 2-s2.0-85217390700OAI: oai:DiVA.org:umu-235676DiVA, id: diva2:1939278
Available from: 2025-02-21 Created: 2025-02-21 Last updated: 2025-02-21Bibliographically approved

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Nyholm, TufveSimkó, Attila

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