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Higher-level gait disorders: a population-based study on prevalence, quality of life, depression and confidence in gait and balance
Umeå University, Faculty of Medicine, Department of Clinical Sciences, Neurosciences.ORCID iD: 0000-0002-4423-9465
Umeå University, Faculty of Medicine, Department of Clinical Sciences, Neurosciences.ORCID iD: 0000-0001-5614-7157
Umeå University, Faculty of Medicine, Department of Clinical Sciences, Neurosciences. Department of Health, Medicine and Caring Sciences, Division of General Practice, Linköping University, Linköping, Sweden.ORCID iD: 0000-0002-0125-9589
Umeå University, Faculty of Medicine, Department of Clinical Sciences, Neurosciences.ORCID iD: 0000-0003-3528-8502
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2025 (English)In: BMJ Neurology Open, ISSN 2632-6140, Vol. 7, no 1, article id e000992Article in journal (Refereed) Published
Abstract [en]

Background: Higher-level gait disorders (HLGDs) are slow, unsteady neurological GDs in older people. GDs can reduce quality of life (QoL) and cause depression. This has not been investigated in HLGD even though some HLGD causes are treatable, potentially affecting associated problems. We aimed to investigate gait and balance confidence, depressive symptoms and QoL in HLGD.

Methods: In a population (n=3769, 65-84y), 798 reported gait impairment (questionnaire) and were clinically examined together with 249 age- and sex-matched controls. Gait property groups were formed: 'HLGD', 'other neurological GD', 'non-neurological GD' or 'no GD'. Swedish Falls Efficacy Scale (FES(S)), Modified Gait Efficacy Scale (mGES), Euro Quality of Life 5-Dimension 5-Level index, Euro Quality of Life Visual Analogue Scale (EQ VAS) and Geriatric Depression Scale-15 (GDS-15) were compared.

Results: In the general population, 38% had GDs, of which 16% (n=87/561) were HLGDs, giving an HLGD prevalence of 5.8%; 26% (n=145/561) were other neurological GDs; and 59% (n=329/561) non-neurological GDs. HLGD had more depressive symptoms than non-neurological GD and no GD (GDS-15 HLGD, 3.9 +/- 3.4; non-neurological GD, 2.5 +/- 2.8; no GD, 1.4 +/- 2.0; p<0.05), lower EQ VAS (HLGD, 63 +/- 17; non-neurological GD, 71 +/- 18; no GD, 82 +/- 14; p<0.001), lower gait confidence (mGES HLGD, 60 +/- 22; non-neurological GD, 74 +/- 21; no GD, 90 +/- 13; p<0.001) and lower balance confidence (FES(S) HLGD, 93 +/- 32; non-neurological GD, 111 +/- 25; no GD, 124 +/- 13; p<0.001).

Conclusions: HLGDs are common and associated with reduced QoL, reduced confidence in gait and balance, and depressive symptoms, emphasising awareness of mental health among older people with slow unsteady gait.

Place, publisher, year, edition, pages
BMJ Publishing Group Ltd, 2025. Vol. 7, no 1, article id e000992
Keywords [en]
Gait, Quality of life, Depression, epidemiology, movement disorders
National Category
Neurosciences Psychiatry
Research subject
Geriatrics; Neurology; Psychiatry
Identifiers
URN: urn:nbn:se:umu:diva-243350DOI: 10.1136/bmjno-2024-000992ISI: 001445007200001PubMedID: 40092839Scopus ID: 2-s2.0-105025048113OAI: oai:DiVA.org:umu-243350DiVA, id: diva2:1990530
Funder
Swedish Foundation for Strategic ResearchSwedish Heart Lung Foundation, 19-21, 20180513The Swedish Brain Foundation, F2022-0216Available from: 2025-08-20 Created: 2025-08-20 Last updated: 2026-01-19Bibliographically approved

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Larsson, JennyHansson, WilliamIsraelsson Larsen, HannaKoskinen, Lars-Owe D.Eklund, AndersMalm, Jan

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