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MUniverse: a simulation and benchmarking suite for motor unit decomposition
I-X Center for AI in Science, Imperial College London, UK; Department of Bioengineering, Imperial College London, UK.
Institute for Modelling and Simulation of Biomechanical Systems, University of Stuttgart, Germany.
Department of Bioengineering, Imperial College London, UK.
Department of Bioengineering, Imperial College London, UK.
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2025 (English)Conference paper, Published paper (Refereed)
Abstract [en]

Neural source separation enables the extraction of individual spike trains from complex electrophysiological recordings. When applied to electromyographic (EMG) signals, it provides a unique window into the motor output of the nervous system by isolating the spiking activity of motor units (MUs). MU decomposition from EMG signals is currently the only scalable neural interfacing approach available in behaving humans and has become foundational in motor neuroscience and neuroprosthetics. However, unlike related domains such as spike sorting or electroencephalography (EEG) analysis, decomposition of EMG signals lacks open benchmarks that reflect the diversity of muscles, movement contexts, and noise sources encountered in practice. To address this gap, we introduce MUniverse, a modular simulation and benchmarking suite for decomposing EMG signals into individual MU spiking activity. MUniverse provides: (1) a simulation stack with a user-friendly interface to a state-of-the-art EMG generator; (2) a curated library of datasets across synthetic, hybrid synthetic-real data with ground truth spikes, and experimental EMG; (3) a set of internal and external decomposition pipelines; and (4) a unified benchmark with well-defined tasks, standard evaluation metrics, and baseline results from established decomposition pipelines. MUniverse is designed for extensibility, reproducibility, and community use, and all datasets are distributed with standardised metadata (Croissant, BIDS). By standardising evaluation and enabling dataset simulation at scale, MUniverse aims to catalyze progress on this long-standing neural signal processing problem.

Place, publisher, year, edition, pages
2025. article id 1735
National Category
Algorithms Neurosciences Medical Modelling and Simulation
Identifiers
URN: urn:nbn:se:umu:diva-247124OAI: oai:DiVA.org:umu-247124DiVA, id: diva2:2017956
Conference
NeurIPS 2025 The Thirty-Ninth Annual Conference on Neural Information Processing Systems, Benchmarks Track, San Diego, USA, December 1, 2025
Funder
The Swedish Brain Foundation, PS2022-0021EU, Horizon Europe, 101055186German Research Foundation (DFG), 548605919Available from: 2025-12-01 Created: 2025-12-01 Last updated: 2025-12-02Bibliographically approved

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fulltext(7438 kB)107 downloads
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Rohlén, Robin

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CiteExportLink to record
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Citation style
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