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A case of tongue twisting during screening of STN-DBS for Parkinson’s disease: a unique form of pyramidal tract activation
Istanbul Health and Technology University, Faculty of Medicine, Department of Neurology, Istanbul, Turkey.
University College London, Institute of Neurology and the National Hospital for Neurology and Neurosurgery, Department of Clinical and Movement Neurosciences, Neurosurgery, Queen Square, London, United Kingdom.
University College London, Institute of Neurology and the National Hospital for Neurology and Neurosurgery, Department of Clinical and Movement Neurosciences, Neurology, Queen Square, London, United Kingdom.
University College London, Institute of Neurology and the National Hospital for Neurology and Neurosurgery, Department of Clinical and Movement Neurosciences, Neurosurgery, Queen Square, London, United Kingdom.
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2025 (English)In: Turkish Neurosurgery, ISSN 1019-5149, Vol. 35, no 6, p. 974-976Article in journal (Refereed) Published
Abstract [en]

Subthalamic nucleus deep brain stimulation (STN-DBS) is a safe and effective therapy for Parkinson’s disease (PD) in selected patients. However, various side effects such as paraesthesia, diplopia, ataxia, worsened akinesia, emotional changes, dysarthria, and muscle contractions can occur due to the current spread to the adjacent structures during the STN-DBS programming sessions. Muscle contractions result from the corticospinal and corticobulbar side effects, which can manifest due to the current spread to the pyramidal tract during DBS programming. Here, we report a case of tongue-twisting movement as a unique corticobulbar side effect of the STN-DBS programming in a patient with PD.

Place, publisher, year, edition, pages
Turkish Neurosurgical Society , 2025. Vol. 35, no 6, p. 974-976
Keywords [en]
Corticobulbar side effects, Parkinson’s disease, STN-DBS
National Category
Neurology
Identifiers
URN: urn:nbn:se:umu:diva-246963DOI: 10.5137/1019-5149.JTN.46831-24.3PubMedID: 41165375Scopus ID: 2-s2.0-105022821380OAI: oai:DiVA.org:umu-246963DiVA, id: diva2:2019340
Available from: 2025-12-05 Created: 2025-12-05 Last updated: 2025-12-05Bibliographically approved

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Hariz, Marwan

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