ACGM: attribute-centric graph modeling network for concurrent missing tabular data imputation and COVID-19 prognosisShow others and affiliations
2026 (English)In: IEEE journal of biomedical and health informatics, ISSN 2168-2194, E-ISSN 2168-2208, Vol. 30, no 4, p. 3307-3320Article in journal (Refereed) Published
Abstract [en]
COVID-19 prognosis using clinical tabular data faces significant challenges due to missing values and class imbalance issues. Existing methods often overlook the complex high-order interrelationship among clinicalattributes and struggle with training stability on imbalanced datasets. We propose ACGM, an attribute-centric graph modeling network that simultaneously addresses missing data imputation and COVID-19 prognosis. ACGM consists of three key modules: an attributes preprocessing module (APM) for coarse-grained imputation initialization, a graph-enhanced attributes imputation module (GEAIM) that models high-order inter-attribute relationships through graph structures, and a graph-enhanced disease prognosis module (GEDPM) that leverages these complex attribute interactions for final prediction. GEAIM and GEDPM employ a mean-teacher strategy with attributes graph matching to preserve high-order relationships, enhance training stability, and maintain structural integrity of attribute interactions. Extensive experiments are conducted on four public COVID-19 tabular datasets, demonstrating the superiority of our ACGM over existing methods. Through comprehensive interpretability analysis, we identify that attributes such as LDH, Difficulty In Breathing, and SaO2 significantly impact COVID-19 prognosis, aligning well with clinical insights and radiologist assessments.
Place, publisher, year, edition, pages
IEEE, 2026. Vol. 30, no 4, p. 3307-3320
Keywords [en]
attribute-centric, COVID-19 prognosis, graph, missing tabular data imputation
National Category
Computer Sciences
Identifiers
URN: urn:nbn:se:umu:diva-252258DOI: 10.1109/JBHI.2025.3618935PubMedID: 41056179Scopus ID: 2-s2.0-105018503443OAI: oai:DiVA.org:umu-252258DiVA, id: diva2:2054141
2026-04-202026-04-202026-04-20Bibliographically approved