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Chronic health conditions and trajectories of depressive symptoms in late adulthood: role of age-friendly community
Department of Aging Services and Management, Nanjing University of Chinese Medicine, Jiangsu, Nanjing, China; School of Public Health and Community Medicine, University of Gothenburg Sahlgrenska Academy, Västra Götaland County, Gothenburg, Sweden; Jiangsu Engineering Research Center for Intelligent TCM Health Services, Nanjing University of Chinese Medicine, Jiangsu, Nanjing, China.
Umeå University, Faculty of Medicine, Department of Epidemiology and Global Health. School of Public Health and Community Medicine, University of Gothenburg Sahlgrenska Academy, Västra Götaland County, Gothenburg, Sweden.ORCID iD: 0000-0003-0556-1483
Umeå University, Faculty of Medicine, Department of Clinical Sciences.
School of Public Health and Community Medicine, University of Gothenburg Sahlgrenska Academy, Västra Götaland County, Gothenburg, Sweden.
2026 (English)In: Journal of Epidemiology and Community Health, ISSN 0143-005X, E-ISSN 1470-2738, article id jech-2025-223769Article in journal (Refereed) Epub ahead of print
Abstract [en]

Background: Contextual factors influence how older adults perceive and adapt to chronic health conditions. We examined the impact of chronic health conditions on trajectories of depressive symptoms among older Chinese adults and investigated whether age-friendly communities buffer this effect.

Methods: We used panel data from the China Health and Retirement Longitudinal Study from 2011 to 2018, including 6122 adults aged ≥50 years (22 198 observations). Factor analysis of mixed data (FAMD) was performed to construct composite variables of community characteristics. The cross-level interactions between community variables and multimorbidity were included in growth curve models to assess the moderating effects.

Results: Individuals with multimorbidity had Centre for Epidemiologic Studies Depression Scale (CES-D) scores that were, on average, 1.60 points higher (95% CI 1.31 to 1.89) than those without chronic conditions, indicating a relatively modest effect size. Associations with depressive symptoms were weaker in more favourable community environments and among individuals with higher participation (all P for interaction<0.001). For multimorbidity, β coefficients were smaller in areas with better infrastructure (1.50 vs 1.73), stronger social services (1.47 vs 1.85) and higher participation (1.47 vs 2.09). A similar pattern was observed for individuals with a single condition, with smaller β coefficients in areas with better infrastructure (0.41 vs 0.79), stronger social services (0.35 vs 0.78) and higher participation (0.35 vs 0.89).

Conclusion: Age-friendly environments may ameliorate the effects of multimorbidity on depressive symptoms. Interventions can target modifiable community-level factors to better support older adults with chronic conditions.

Place, publisher, year, edition, pages
BMJ Publishing Group Ltd, 2026. article id jech-2025-223769
Keywords [en]
Aging, Cohort studies, Depression
National Category
Epidemiology Public Health, Global Health and Social Medicine Gerontology, specialising in Medical and Health Sciences
Identifiers
URN: urn:nbn:se:umu:diva-255474DOI: 10.1136/jech-2025-223769ISI: 001793186100001PubMedID: 42285745Scopus ID: 2-s2.0-105041853011OAI: oai:DiVA.org:umu-255474DiVA, id: diva2:2077248
Available from: 2026-06-23 Created: 2026-06-23 Last updated: 2026-06-23

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Ng, NawiJacobsson, Lars

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