The article develops the concept of returnees' cultural jetlag as an aspect of highly skilled professionals' post-mobility experiences, based on an analysis of Swedish medical professionals' experiences of working abroad and returning to Sweden. Its focus is on the experience of the post-mobility phase upon return to the country of residence, and the process which we conceptualize as "returnees' cultural jetlag", consisting of initial bewilderment, estrangement, and the endeavour to re-establish one's cultural bearings, resulting in a new insights and perspectives on the taken-for-granted and a gradual, reflexive (re)adjustment. The article proposes theoretical refinements in relation to the more established concept of "reverse culture shock".