Although studies on trust as an organizing principle have advanced our understanding of organizing in the context of interdependency and uncertainty, research has not yet explored the distinct roles of trust and distrust, and how they simultaneously, and synergistically affect interorganizational interactions under interpartner uncertainty. We enrich the theorizing based on a case study of the Swedish robotics and automation ecosystem where interpartner uncertainty—due to complex interdependencies, frequent coopetitive interactions, and temporal alignment of actors in multiple projects—is a key organizing challenge. We identify distinct orienting and enabling mechanisms of trust and distrust respectively, which both individually and synergistically support firms in maintaining fruitful interactions in the face of uncertainty. Furthermore, we integrate the mechanisms of trust and distrust into a model explaining how trust and distrust as organizing principles interact to give rise to watchful blindness.