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End-of-life care in amyotrophic lateral sclerosis: A comparative registry study
Department of Surgery, Östersund Hospital, Östersund, Sweden.
Umeå University, Faculty of Medicine, Department of Radiation Sciences, Oncology.
2021 (English)In: Acta Neurologica Scandinavica, ISSN 0001-6314, E-ISSN 1600-0404, Vol. 143, no 5, p. 481-488Article in journal (Refereed) Published
Abstract [en]

Background: Amyotrophic lateral sclerosis (ALS) is a fatal disease requiring palliative care. End‐of‐life care has been well studied in patients with incurable cancer, but less is known about the quality of such care for patients with ALS.

Aim: To study whether the quality of end‐of‐life care the last week in life for patients dying from ALS differed compared to patients with cancer in terms of registered symptoms, symptom management, and communication.

Design: This retrospective comparative registry study used data from the Swedish Registry of Palliative Care for 2012–2016. Each patient with ALS (n = 825) was matched to 4 patients with cancer (n = 3,300).

Results: Between‐group differences in assessments for pain and other symptoms were significant (p < 0.01), and patients with ALS had fewer as‐needed injection drugs prescribed than patients with cancer. Patients with ALS also had dyspnea and anxiety significantly more often than patients with cancer. There was no significant difference in communication about transition to end‐of‐life care between the two groups. Patients dying from ALS received artificial nutrition on their last day of life significantly more often than patients with cancer.

Conclusions: The results indicate that patients with ALS receive poorer end‐of‐life care than patients dying from cancer in terms of validated symptom assessments, prescription of as‐needed drugs, and timely cessation of artificial nutrition. Educational efforts seem needed to facilitate equal care of dying patients, regardless of diagnosis.

Place, publisher, year, edition, pages
John Wiley & Sons, 2021. Vol. 143, no 5, p. 481-488
Keywords [en]
amyotrophic lateral sclerosis, palliative care, quality indicators, terminal care
National Category
Neurology Nursing
Identifiers
URN: urn:nbn:se:umu:diva-177498DOI: 10.1111/ane.13370ISI: 000591436100001PubMedID: 33141927Scopus ID: 2-s2.0-85096643895OAI: oai:DiVA.org:umu-177498DiVA, id: diva2:1508544
Available from: 2020-12-10 Created: 2020-12-10 Last updated: 2023-03-24Bibliographically approved

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Axelsson, Bertil

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