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Does sensorimotor function predict graft rupture, contra-lateral injury or failure to return to sports after ACL reconstruction?: A protocol for the STOP Graft Rupture study
Umeå University, Faculty of Medicine, Department of Community Medicine and Rehabilitation. Department of Health Sciences, Lund University, Lund, Sweden.ORCID iD: 0000-0002-3282-6320
Umeå University, Faculty of Medicine, Department of Community Medicine and Rehabilitation, Section of Physiotherapy.ORCID iD: 0000-0002-0366-4609
2021 (English)In: BMJ Open, E-ISSN 2044-6055, Vol. 11, article id e042031Article in journal (Refereed) Published
Abstract [en]

Introduction: People with anterior cruciate ligament (ACL) reconstruction (ACLR) are at high risk of sustaining a graft rupture and/or contra-lateral ACL injury. The main factors that may predispose individuals for subsequent ACL injuries are, however, not established. To reduce the risk of reinjuries, it is of particular interest to identify modifiable risk-factors, for instance, those related to sensorimotor control which are responsive to training. The aim of the current study protocol is to present the design of our prospective cohort study STOP Graft Rupture investigating sensorimotor function as predictors for graft rupture, contra-lateral ACL injury and/or failure to return to sport (RTS) within 3 years following ACLR.

Methods and analysis: We aim to recruit 200 individuals (15–35 years, ~50% women) with ACLR from Norrland University Hospital, Umeå and Lund University Hospital, Lund, Sweden. Participants will be assessed with a comprehensive test battery for sensorimotor muscle function, including hop performance, muscle strength, muscle activation, hip and ankle range of motion and postural orientation as well as patient-reported function 1 year after ACLR (baseline). For a subgroup of individuals (Umeå cohort), 3D kinematics and joint position sense will also be evaluated. At follow-up (≥3 years post-ACLR), the participants will be asked to answer questions related to new ACL injuries to either knee and about RTS. Separate logistic regression models, adjusting for possible confounders, will be used to evaluate the influence of the different sensorimotor predictors on the prospective outcomes (graft rupture, contra-lateral ACL injury, RTS).

Ethics and dissemination: This study was approved by the Swedish Ethical Review Board (Dnr 2016/319 and Dnr 2019-04037). The results will be published in international peer-reviewed scientific journals and presented at clinical and scientific congresses.

Trial registration number: NCT04162613.

Place, publisher, year, edition, pages
BMJ Publishing Group Ltd, 2021. Vol. 11, article id e042031
National Category
Physiotherapy
Identifiers
URN: urn:nbn:se:umu:diva-178522DOI: 10.1136/bmjopen-2020-042031ISI: 000610242100006PubMedID: 33419913Scopus ID: 2-s2.0-85099198116OAI: oai:DiVA.org:umu-178522DiVA, id: diva2:1517384
Available from: 2021-01-13 Created: 2021-01-13 Last updated: 2023-08-28Bibliographically approved

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Cronström, AnnaHäger, Charlotte

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