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Goal-dependent tuning of muscle spindle receptors during movement preparation
Umeå University, Faculty of Medicine, Department of Integrative Medical Biology (IMB).
Umeå University, Faculty of Medicine, Department of Integrative Medical Biology (IMB).ORCID iD: 0000-0001-9890-2974
2021 (English)In: Science Advances, E-ISSN 2375-2548, Vol. 7, no 9, article id eabe0401Article in journal (Refereed) Published
Abstract [en]

Voluntary movements are believed to undergo preparation before they are executed. Preparatory activity can benefit reaction time and the quality of planned movements, but the neural mechanisms at work during preparation are unclear. For example, there are no overt changes in muscle force during preparation. Here, using an instructed-delay manual task, we demonstrate a decrease in human muscle afferent activity (primary spindles) when preparing to reach targets in directions associated with stretch of the spindle-bearing muscle. This goal-dependent modulation of proprioceptors began early after target onset but was markedly stronger at the latter parts of the preparatory period. Moreover, whole-arm perturbations during reach preparation revealed a modulation of stretch reflex gains (shoulder and upper arm muscles) that reflected the observed changes in spindle activity. We suggest that one function of central preparatory activity is to tune muscle stiffness according to task goals via the independent control of muscle spindle sensors.

Place, publisher, year, edition, pages
2021. Vol. 7, no 9, article id eabe0401
National Category
Physiology
Identifiers
URN: urn:nbn:se:umu:diva-181741DOI: 10.1126/sciadv.abe0401ISI: 000622481300024Scopus ID: 2-s2.0-85102097912OAI: oai:DiVA.org:umu-181741DiVA, id: diva2:1539251
Available from: 2021-03-23 Created: 2021-03-23 Last updated: 2023-09-05Bibliographically approved

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Papaioannou, StylianosDimitriou, Michael

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CiteExportLink to record
Permanent link

Direct link
Cite
Citation style
  • apa
  • ieee
  • modern-language-association-8th-edition
  • vancouver
  • Other style
More styles
Language
  • de-DE
  • en-GB
  • en-US
  • fi-FI
  • nn-NO
  • nn-NB
  • sv-SE
  • Other locale
More languages
Output format
  • html
  • text
  • asciidoc
  • rtf