Umeå universitets logga

umu.sePublikationer
Ändra sökning
RefereraExporteraLänk till posten
Permanent länk

Direktlänk
Referera
Referensformat
  • apa
  • ieee
  • modern-language-association-8th-edition
  • vancouver
  • Annat format
Fler format
Språk
  • de-DE
  • en-GB
  • en-US
  • fi-FI
  • nn-NO
  • nn-NB
  • sv-SE
  • Annat språk
Fler språk
Utmatningsformat
  • html
  • text
  • asciidoc
  • rtf
Neurodevelopment and growth until 6.5 years of infants who consumed a low-energy, low-protein formula supplemented with bovine milk fat globule membranes: a randomized controlled trial
Umeå universitet, Medicinska fakulteten, Institutionen för klinisk vetenskap, Pediatrik.
Umeå universitet, Medicinska fakulteten, Institutionen för klinisk vetenskap, Pediatrik.
Umeå universitet, Samhällsvetenskapliga fakulteten, Institutionen för psykologi.ORCID-id: 0000-0003-0240-3690
Umeå universitet, Medicinska fakulteten, Institutionen för klinisk vetenskap, Pediatrik.
Visa övriga samt affilieringar
2021 (Engelska)Ingår i: American Journal of Clinical Nutrition, ISSN 0002-9165, E-ISSN 1938-3207, Vol. 113, nr 3, s. 586-592Artikel i tidskrift (Refereegranskat) Published
Abstract [en]

BACKGROUND: We previously reported results from a randomized controlled trial in which we found that Swedish infants consuming an experimental low-energy, low-protein formula (EF) supplemented with bovine milk fat globule membranes (MFGMs) until 6 mo of age had several positive outcomes, including better performance in the cognitive domain of Bayley Scales of Infant and Toddler Development 3rd Edition at 12 mo of age, and higher plasma cholesterol concentrations during the intervention, than infants consuming standard formula (SF).

OBJECTIVES: We aimed to evaluate neurodevelopment, growth, and plasma cholesterol status at 6 and 6.5 y of age in the same study population.

METHODS: We assessed cognitive and executive functions using the Wechsler Intelligence Scale for Children 4th Edition (WISC-IV), Brown Attention-Deficit Disorder Scales for Children and Adolescents (Brown-ADD), and Quantified Behavior (Qb) tests, and behavior using the Child Behavior Checklist (CBCL) and Teacher's Report Form (TRF), at 6.5 y of age. Anthropometrics and plasma lipids were assessed at 6 y of age.

RESULTS: There were no differences between the EF and SF groups in any of the subscales in WISC-IV or Brown-ADD at 6.5 y of age, in the proportion of children with scores outside the normal range in the Qb test, nor in clinical or borderline indications of problems in adaptive functioning from parental and teacher's scoring using the CBCL and TRF. There were no differences between the EF and SF groups in weight, length, or head or abdominal circumferences, nor in plasma concentrations of homocysteine, lipids, insulin, or glucose.

CONCLUSIONS: Among children who as infants consumed a low-energy, low-protein formula supplemented with bovine MFGMs, there were no effects on neurodevelopment, growth, or plasma cholesterol status 6-6.5 y later.

Ort, förlag, år, upplaga, sidor
Oxford University Press, 2021. Vol. 113, nr 3, s. 586-592
Nyckelord [en]
behavior, breastfeeding, cholesterol, cognition, energy, executive functions, infant formula, milk fat globule membranes, protein
Nationell ämneskategori
Pediatrik Näringslära
Identifikatorer
URN: urn:nbn:se:umu:diva-181997DOI: 10.1093/ajcn/nqaa354ISI: 000628694500014Scopus ID: 2-s2.0-85102906283OAI: oai:DiVA.org:umu-181997DiVA, id: diva2:1543678
Tillgänglig från: 2021-04-12 Skapad: 2021-04-12 Senast uppdaterad: 2023-09-05Bibliografiskt granskad

Open Access i DiVA

fulltext(514 kB)112 nedladdningar
Filinformation
Filnamn FULLTEXT01.pdfFilstorlek 514 kBChecksumma SHA-512
e6f4a9760014e0e7359e214f0aa538eec3cd3c429dad9857dd61df6527b6d286d757b3c0229ff2c114c4d3366d223b90c1acba5e33524f21ae7c945bbf9ebf1e
Typ fulltextMimetyp application/pdf

Övriga länkar

Förlagets fulltextScopus

Person

Timby, NiklasAdamsson, MarieDomellöf, ErikGrip, ToveHernell, OlleDomellöf, Magnus

Sök vidare i DiVA

Av författaren/redaktören
Timby, NiklasAdamsson, MarieDomellöf, ErikGrip, ToveHernell, OlleDomellöf, Magnus
Av organisationen
PediatrikInstitutionen för psykologi
I samma tidskrift
American Journal of Clinical Nutrition
PediatrikNäringslära

Sök vidare utanför DiVA

GoogleGoogle Scholar
Totalt: 112 nedladdningar
Antalet nedladdningar är summan av nedladdningar för alla fulltexter. Det kan inkludera t.ex tidigare versioner som nu inte längre är tillgängliga.

doi
urn-nbn

Altmetricpoäng

doi
urn-nbn
Totalt: 338 träffar
RefereraExporteraLänk till posten
Permanent länk

Direktlänk
Referera
Referensformat
  • apa
  • ieee
  • modern-language-association-8th-edition
  • vancouver
  • Annat format
Fler format
Språk
  • de-DE
  • en-GB
  • en-US
  • fi-FI
  • nn-NO
  • nn-NB
  • sv-SE
  • Annat språk
Fler språk
Utmatningsformat
  • html
  • text
  • asciidoc
  • rtf