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Educational attainment does not influence brain aging
Umeå University, Faculty of Medicine, Department of Integrative Medical Biology (IMB). Umeå University, Faculty of Medicine, Umeå Centre for Functional Brain Imaging (UFBI). Umeå University, Faculty of Medicine, Department of Radiation Sciences, Diagnostic Radiology. Center for Lifespan Changes in Brain and Cognition, University of Oslo, Oslo, Norway.
Center for Lifespan Changes in Brain and Cognition, University of Oslo, Oslo, Norway.
Umeå University, Faculty of Medicine, Umeå Centre for Functional Brain Imaging (UFBI).ORCID iD: 0000-0003-1524-0851
Danish Research Centre for Magnetic Resonance, Centre for Functional and Diagnostic Imaging and Research, Copenhagen University Hospital, Amager and Hvidovre, Hvidovre, Denmark.
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2021 (English)In: Proceedings of the National Academy of Sciences of the United States of America, ISSN 0027-8424, E-ISSN 1091-6490, Vol. 118, no 18, article id 2101644118Article in journal (Refereed) Published
Abstract [en]

Education has been related to various advantageous lifetime outcomes. Here, using longitudinal structural MRI data (4,422 observations), we tested the influential hypothesis that higher education translates into slower rates of brain aging. Cross-sectionally, education was modestly associated with regional cortical volume. However, despite marked mean atrophy in the cortex and hippocampus, education did not influence rates of change. The results were replicated across two independent samples. Our findings challenge the view that higher education slows brain aging.

Place, publisher, year, edition, pages
2021. Vol. 118, no 18, article id 2101644118
Keywords [en]
Aging, Cerebral cortex, Education, Hippocampus, Reserve
National Category
Neurosciences
Identifiers
URN: urn:nbn:se:umu:diva-183515DOI: 10.1073/pnas.2101644118ISI: 000647171500006Scopus ID: 2-s2.0-85105651544OAI: oai:DiVA.org:umu-183515DiVA, id: diva2:1557328
Funder
Knut and Alice Wallenberg FoundationAvailable from: 2021-05-25 Created: 2021-05-25 Last updated: 2023-09-05Bibliographically approved

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Lundquist, AndersBoraxbekk, Carl-JohanPudas, Sara

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