Educational attainment does not influence brain aging Department of Medicine, Faculty of Medicine and Health Sciences and Neurosciences Institute, University of Barcelona, Barcelona, Spain.
Center for Lifespan Changes in Brain and Cognition, University of Oslo, Oslo, Norway; Lübeck Interdisciplinary Platform for Genome Analytics, University of Lübeck, Lübeck, Germany.
Center for Lifespan Psychology, Max Planck Institute for Human Development, Berlin, Germany; Max Planck University College London Centre for Computational Psychiatry and Ageing Research, Berlin, Germany.
Vitas AS, Research Park, Oslo, Norway; Department of Nutrition, Institute of Basic Medical Sciences, Faculty of Medicine, Medicine/University of Oslo, Oslo, Norway.
Warneford Hospital, University of Oxford, Oxford, United Kingdom.
Faculté de Psychologie et des Sciences de l'Education, Université de Genève, Geneva, Switzerland.
Medical Research Council Cognition and Brain Sciences Unit, Department of Psychiatry, University of Cambridge, Cambridge, United Kingdom.
Department of Medicine, Faculty of Medicine and Health Sciences and Neurosciences Institute, University of Barcelona, Barcelona, Spain.
Medical Research Council Cognition and Brain Sciences Unit, Department of Psychiatry, University of Cambridge, Cambridge, United Kingdom; Cognitive Neuroscience Department, Donders Institute for Brain, Cognition and Behavior, Radboud University Medical Center, Nijmegen, Netherlands.
Center for Lifespan Psychology, Max Planck Institute for Human Development, Berlin, Germany.
Medical Research Council Cognition and Brain Sciences Unit, Department of Psychiatry, University of Cambridge, Cambridge, United Kingdom.
Center for Lifespan Psychology, Max Planck Institute for Human Development, Berlin, Germany; Department of Psychiatry and Psychotherapy, University Clinic Hamburg-Eppendorf, Hamburg, Germany.
Center for Lifespan Psychology, Max Planck Institute for Human Development, Berlin, Germany; Max Planck University College London Centre for Computational Psychiatry and Ageing Research, Berlin, Germany.
Department of Psychiatry, Amsterdam University Medical Center, Vrije Universiteit, Amsterdam, Netherlands.
Center for Lifespan Changes in Brain and Cognition, University of Oslo, Oslo, Norway.
Department of Medicine, Faculty of Medicine and Health Sciences and Neurosciences Institute, University of Barcelona, Barcelona, Spain.
Center for Lifespan Changes in Brain and Cognition, University of Oslo, Oslo, Norway; Department of Radiology and Nuclear Medicine, Oslo University Hospital, Oslo, Norway.
Center for Lifespan Changes in Brain and Cognition, University of Oslo, Oslo, Norway; Department of Radiology and Nuclear Medicine, Oslo University Hospital, Oslo, Norway.
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2021 (Engelska) Ingår i: Proceedings of the National Academy of Sciences of the United States of America, ISSN 0027-8424, E-ISSN 1091-6490, Vol. 118, nr 18, artikel-id 2101644118Artikel i tidskrift (Refereegranskat) Published
Abstract [en]
Education has been related to various advantageous lifetime outcomes. Here, using longitudinal structural MRI data (4,422 observations), we tested the influential hypothesis that higher education translates into slower rates of brain aging. Cross-sectionally, education was modestly associated with regional cortical volume. However, despite marked mean atrophy in the cortex and hippocampus, education did not influence rates of change. The results were replicated across two independent samples. Our findings challenge the view that higher education slows brain aging.
Ort, förlag, år, upplaga, sidor 2021. Vol. 118, nr 18, artikel-id 2101644118
Nyckelord [en]
Aging, Cerebral cortex, Education, Hippocampus, Reserve
Nationell ämneskategori
Neurovetenskaper
Identifikatorer URN: urn:nbn:se:umu:diva-183515 DOI: 10.1073/pnas.2101644118 ISI: 000647171500006 Scopus ID: 2-s2.0-85105651544 OAI: oai:DiVA.org:umu-183515 DiVA, id: diva2:1557328
Forskningsfinansiär Knut och Alice Wallenbergs Stiftelse 2021-05-252021-05-252023-09-05 Bibliografiskt granskad