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Survival after radical cystectomy during holiday periods
Department of Urology, Skåne University Hospital, Malmö, Sweden; Institution of Translational Medicine, Lund University, Malmö, Sweden.
Institution of Translational Medicine, Lund University, Malmö, Sweden; Regional Cancer Centre South, Region Skåne, Lund, Sweden.
Department of Clinical and Experimental Medicine, Division of Urology, Linköping University, Linköping, Sweden.
Department of Clinical Sciences, Danderyd Hospital, Karolinska Institute, Stockholm, Sweden.
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2021 (English)In: Scandinavian journal of urology, ISSN 2168-1805, E-ISSN 2168-1813, Vol. 55, no 4, p. 276-280Article in journal (Refereed) Published
Abstract [en]

OBJECTIVE: For patients undergoing radical cystectomy for bladder cancer, a procedure requiring complex urinary tract reconstruction prone to major postoperative complications, the timing and quality of the surgery have been associated with outcomes.

PATIENTS AND METHODS: This study investigated if radical cystectomy for bladder cancer performed during holiday periods had worse disease-specific (DSS) and overall survival (OS), higher 90-day mortality and risk of readmissions. All patients operated on with radical cystectomy for primary bladder cancer during 1997-2014 with holiday periods as exposure (with one narrow (7 weeks) and one wider (14 weeks) definition) in the Swedish population-based bladder cancer research-database (BladderBaSe) were studied. DSS and OS after radical cystectomy during holiday periods were analysed with Cox regression models adjusted for sex, age, comorbidity, marital status, T-stage and nodal metastases, neoadjuvant chemotherapy, hospital volume and year of cystectomy.

RESULTS: Surgery during the holiday periods (narrow and wide definitions) were not associated with DSS (Hazard ratio [HR] = 1.05, 95% confidence interval [95% CI] = 0.90-1.21 and HR = 1.04, 95% CI = 0.91-1.17), respectively. HRs for OS were similar, and no associations between radical cystectomy during any of the holiday period definitions and 90-day mortality and readmission were found.

CONCLUSION: Survival after radical cystectomy in Sweden is similar during holiday and non-holiday periods.

Place, publisher, year, edition, pages
Taylor & Francis Group, 2021. Vol. 55, no 4, p. 276-280
Keywords [en]
Bladder cancer, holiday periods, radical cystectomy, survival
National Category
Urology and Nephrology
Identifiers
URN: urn:nbn:se:umu:diva-184522DOI: 10.1080/21681805.2021.1938665ISI: 000661345900001PubMedID: 34124994Scopus ID: 2-s2.0-85107846587OAI: oai:DiVA.org:umu-184522DiVA, id: diva2:1566306
Funder
Swedish Cancer Society, 2019/62Swedish Cancer Society, 2017/278Region Skåne, [REGSKANE-622351Available from: 2021-06-15 Created: 2021-06-15 Last updated: 2022-05-12Bibliographically approved

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Sherif, AmirSöderkvist, KarinHäggström, Christel

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CiteExportLink to record
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