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Impact of bariatric surgery on moderate to severe psoriasis: A retrospective nationwide registry study
Department of Dermatology and Venereology, Institute of Clinical Sciences, The Sahlgrenska Academy, University of Gothenburg, Sweden; Department of Dermatology and Venereology, Region Västra Götaland, Sahlgrenska University Hospital, Sweden.
Occupational and Environmental Medicine, School of Public Health and Community Medicine, Institute of Medicine, The Sahlgrenska Academy, University of Gothenburg, Gothenburg, Sweden.
Department of Surgery, Faculty of Medicine and Health, Örebro University, Örebro, Sweden.
Umeå University, Faculty of Medicine, Department of Public Health and Clinical Medicine, Dermatology and Venerology.ORCID iD: 0000-0002-3858-8474
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2021 (English)In: Acta Dermato-Venereologica, ISSN 0001-5555, E-ISSN 1651-2057, Vol. 101, no 6, article id adv00487Article in journal (Refereed) Published
Abstract [en]

Studies of the effects of bariatric surgery on psoriasis are few, with conflicting results. By linking the Swedish National Register for Systemic Treatment of Psoriasis (PsoReg) with the Scandinavian Obesity Surgery Registry (SOReg), individuals with psoriasis who had undergone bariatric surgery in Sweden during 2008 to 2018 were identified, and matched with data for patients with psoriasis in PsoReg. Psoriasis Area Severity Index (PASI) and Dermatology Life Quality Index (DLQI) were compared between the groups. Altogether, 50 operated individuals (median body mass index (BMI) 38.7 kg/m2) and 91 non-operated individuals (median BMI 33.0 kg/m2) were included. Control of disease at baseline was good in both groups. Linear mixed models showed no significant difference in psoriasis disease burden, measured as changes in mean PASI (ΔPASI) (–1.2, p = 0.43) and DLQI (ΔDLQI) (–2.2, p = 0.34). In summary, this study demonstrated no significant effect of bariatric surgery on psoriasis disease burden in patients with relatively well-controlled moderate to severe psoriasis.

Place, publisher, year, edition, pages
2021. Vol. 101, no 6, article id adv00487
Keywords [en]
Bariatric surgery, Body mass index, Dermatology Life Quality Index, Obesity, Psoriasis, Psoriasis Area Severity Index, Scandinavian Obesity Surgery Registry, Swedish National Register for Systemic Treatment of Psoriasis
National Category
Dermatology and Venereal Diseases
Identifiers
URN: urn:nbn:se:umu:diva-186413DOI: 10.2340/00015555-3825PubMedID: 33954800Scopus ID: 2-s2.0-85110533564OAI: oai:DiVA.org:umu-186413DiVA, id: diva2:1582204
Funder
Forte, Swedish Research Council for Health, Working Life and WelfareAvailable from: 2021-07-29 Created: 2021-07-29 Last updated: 2021-07-29Bibliographically approved

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Schmitt-Egenolf, Marcus

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