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Occupational noise exposure and Raynaud's phenomenon: a nested case-control study
Umeå University, Faculty of Medicine, Department of Public Health and Clinical Medicine, Section of Sustainable Health.ORCID iD: 0000-0001-6082-8465
Umeå University, Faculty of Medicine, Department of Public Health and Clinical Medicine, Section of Sustainable Health.
Umeå University, Faculty of Medicine, Department of Public Health and Clinical Medicine, Section of Sustainable Health.ORCID iD: 0000-0001-7077-2389
2021 (English)In: International Journal of Circumpolar Health, ISSN 1239-9736, E-ISSN 2242-3982, Vol. 80, no 1, article id 1969745Article in journal (Refereed) Published
Abstract [en]

The primary aim of this study was to determine if self-reported occupational noise exposure was associated with Raynaud's phenomenon. In northern Sweden, a nested case-control study was performed on subjects reporting Raynaud's phenomenon (N=461), and controls (N=763) matched by age, sex and geographical location. The response rate to the exposure questionnaire was 79.2%. The study showed no statistically significant association between occupational noise exposure and reporting Raynaud's phenomenon (OR 1.10; 95% CI 0.83-1.46) in simple analyses. However, there was a trend towards increasing OR for Raynaud's phenomenon with increasing noise exposure, although not statistically significant. Also, there was a significant association between noise exposure and hearing loss (OR 2.76; 95% CI 2.00-3.81), and hearing loss was associated with reporting Raynaud's phenomenon (OR 1.52; 95% CI 1.03-2.23) in a multiple regression model. In conclusion, self-reported occupational noise exposure was not statistically significantly associated with Raynaud's phenomenon, but there was a dose-effect trend. In addition, the multiple model showed a robust association between hearing loss and Raynaud's phenomenon. These findings offer some support for a common pathophysiological background for Raynaud's phenomenon and hearing loss among noise-exposed workers, possibly through noise-induced vasoconstriction.

Place, publisher, year, edition, pages
Taylor & Francis Group, 2021. Vol. 80, no 1, article id 1969745
Keywords [en]
Raynaud disease, Sweden, hand-arm vibration syndrome, hearing loss, heredity, noise, occupational
National Category
Occupational Health and Environmental Health
Research subject
Occupational and Environmental Medicine
Identifiers
URN: urn:nbn:se:umu:diva-187081DOI: 10.1080/22423982.2021.1969745ISI: 000686792700001PubMedID: 34415235Scopus ID: 2-s2.0-85113766273OAI: oai:DiVA.org:umu-187081DiVA, id: diva2:1589804
Funder
Region Västerbotten, RV-646641Region Västerbotten, RV-834331Available from: 2021-09-01 Created: 2021-09-01 Last updated: 2021-09-16Bibliographically approved

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Stjernbrandt, AlbinPettersson, Hans

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