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Contact allergy to haptens in the Swedish baseline series: Results from the Swedish Patch Test Register (2010 to 2017)
Department of Dermatology, Central Hospital, Karlstad, Sweden; Centre for Clinical Research and Education, Region Värmland, Karlstad, Sweden.
Department of Occupational and Environmental Dermatology, Skåne University Hospital, Lund University, Malmö, Sweden.
Department of Occupational and Environmental Medicine, Faculty of Medicine and Health, Örebro University, Örebro, Sweden.
Department of Dermatology and Venereology, Institute of Clinical Sciences, Sahlgrenska Academy, University of Gothenburg, Gothenburg, Sweden; Department of Dermatology and Venereology, Sahlgrenska University Hospital, Region Västra Götaland, Gothenburg, Sweden.
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2022 (Engelska)Ingår i: Contact Dermatitis, ISSN 0105-1873, E-ISSN 1600-0536, Vol. 86, nr 3, s. 175-188Artikel i tidskrift (Refereegranskat) Published
Abstract [en]

Background: Allergic contact dermatitis has considerable public health impact and causative haptens vary over time.

Objectives: To report the prevalence of contact allergy to allergens in the Swedish baseline series 2010 to 2017, as registered in the Swedish Patch Test Register.

Methods: Results and demographic information for patients tested with the Swedish baseline series in 2010 to 2017 were analysed.

Results: Data for 21 663 individuals (females 69%) were included. Females had significantly more positive patch tests (54% vs 40%). The reaction prevalence rates were highest for nickel sulfate (20.7%), fragrance mix I (7.1%), Myroxylon pereirae (6.9%), potassium dichromate (6.9%), cobalt chloride (6.8%), methylchloroisothiazolinone/methylisothiazolinone (MCI/MI; 6.4%), MI (3.7%), colophonium (3.5%), fragrance mix II (3.2%), and formaldehyde (3.2%). Myroxylon pereirae reaction prevalence increased from 5% in 2010 to 9% in 2017 and that for methyldibromo glutaronitrile from 3.1% to 4.6%. MCI/MI and MI reactions decreased in prevalence after 2014. Nickel reaction prevalence decreased among females aged 10 to 19 years.

Conclusions: Nickel remains the most common sensitizing agent, with reaction prevalence decreasing among females younger than 20 years. The changes in MCI/MI and MI reaction prevalence mirrored those in Europe. The register can reveal changes in contact allergy prevalence over time among patients patch tested in Sweden.

Ort, förlag, år, upplaga, sidor
John Wiley & Sons, 2022. Vol. 86, nr 3, s. 175-188
Nyckelord [en]
contact allergy, contact dermatitis, eczema, fragrance, methylchloroisothiazolinone, methylisothiazolinone, nickel, patch test, preservative, Sweden, Swedish baseline series
Nationell ämneskategori
Dermatologi och venereologi
Identifikatorer
URN: urn:nbn:se:umu:diva-189622DOI: 10.1111/cod.13996ISI: 000716808600001PubMedID: 34704261Scopus ID: 2-s2.0-85125012294OAI: oai:DiVA.org:umu-189622DiVA, id: diva2:1612075
Tillgänglig från: 2021-11-17 Skapad: 2021-11-17 Senast uppdaterad: 2023-05-24Bibliografiskt granskad

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Glas, BoStenberg, Berndt

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